Abstract:
:In 10 patients with chronic autonomic failure, the sympathetic perivascular nerve plexuses from quadriceps muscle biopsies were studied by catecholamine fluorescence and electronmicroscopy. There was almost complete absence of catecholamine fluorescence and fewer than normal numbers of small granular (noradrenergic) vesicles in all nerves studied. The most marked depletion of noradrenergic vesicles was seen in two of the patients with pure autonomic failure, but more studies are needed for a full quantitative comparison of pure autonomic failure and autonomic failure with multiple system atrophy (Shy-Drager syndrome).
journal_name
Neurologyjournal_title
Neurologyauthors
Bannister R,Crowe R,Eames R,Burnstock Gdoi
10.1212/wnl.31.12.1501subject
Has Abstractpub_date
1981-12-01 00:00:00pages
1501-6issue
12eissn
0028-3878issn
1526-632Xjournal_volume
31pub_type
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