Abstract:
INTRODUCTION:Rates of lung cancer in women have been increasing continually for several years. The basic surgical management of this condition is the same in both sexes but a number of differences are apparent. METHODS:We analysed data entered onto the Epithor database between June 2002 and June 2006 concerning 8535 surgical resections performed in primary lung cancer. RESULTS:22.5 percent of patients were women. They were significantly younger (59.6 years vs 62.7 years) and had a lower BMI (24.7 kg x m(-2) vs 25.5 kg x m(-2)). They were in a better physical condition in terms of American Society of Anaesthesiology score and performance status, with better preserved lung function and fewer co-morbidities (1.8 vs 2.1) compared to men. The percentage of adenocarcinomas was higher in women and a higher proportion had early stage disease. 30 day mortality was three times as high in men who also experienced much greater post-operative morbidity. Multivariate analysis revealed an odds ratio of 0.49 (95% CI 0.3-0.8) for mortality and 0.54 (95% CI 0.4-0.6) for morbidity in women compared to men. CONCLUSION:Women with lung cancer have less risk of post-operative morbidity and mortality than men. These data suggest that they might be able to benefit from more aggressive perioperative therapy.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Brouchet L,Mazieres J,Bauvin E,Bigay-Game L,Renaud C,Berjaud J,Dahan Mdoi
10.1016/s0761-8425(07)91390-xsubject
Has Abstractpub_date
2007-09-01 00:00:00pages
877-82issue
7eissn
0761-8425issn
1776-2588pii
MDOI-RMR-09-2007-24-7-0761-8425-101019-200720093journal_volume
24pub_type
杂志文章abstract::We report a case of thrombo-embolic disease in which we were able to detect the presence of serum antiphospholipid auto-antibodies. The existence of antiphospholipid auto-antibodies has already been described in cases of recurrent thrombo-embolism. The thrombogenic role is only partially explained, but would for the g...
journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
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doi:10.1016/j.rmr.2015.07.001
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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journal_title:Revue des maladies respiratoires
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doi:
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
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journal_title:Revue des maladies respiratoires
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doi:
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journal_title:Revue des maladies respiratoires
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更新日期:2001-10-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 临床试验,杂志文章
doi:
更新日期:2003-11-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2010.06.022
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2010.07.003
更新日期:2010-09-01 00:00:00
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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更新日期:2017-03-01 00:00:00