[Severe pneumonia due to cytomegalovirus in chronic obstructive pulmonary disease].

Abstract:

UNLABELLED:Severe pneumonia due to cytomegalovirus in chronic obstructive pulmonary disease. INTRODUCTION:We describe two cases of immunocompetent patients with chronic obstructive pulmonary disease (COPD) who developed severe cytomegalovirus (CMV) pneumonia. The clinical and radiological context and CMV replication in broncho-alveolar lavage suggested a diagnosis of CMV pneumonia. CASE HISTORIES:We report two cases in patients with moderate chronic obstructive pulmonary disease not treated with long-term steroid therapy who developed bilateral pneumonia with hypoxaemia. The only pathogen identified was CMV with replication of the virus in the broncho-alveolar lavage. Investigation failed to detect any associated immune deficiency. CONCLUSION:Severe cytomegalovirus pneumonia could be encouraged by the existence of chronic obstructive pulmonary disease due to local inflammatory changes.

journal_name

Rev Mal Respir

authors

Bosc C,Clement M,Deroux A,Mammar A,Pison C,Camara B

doi

10.1016/j.rmr.2013.09.013

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

435-8

issue

5

eissn

0761-8425

issn

1776-2588

pii

S0761-8425(13)00261-1

journal_volume

31

pub_type

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