[Lung cancer and HIV infection].

Abstract:

:AIDS was the cause of the majority of deaths from HIV infection before 1996 but since the introduction of antiretroviral therapies the causes of mortality have changed considerably. In 2010, 75 % of deaths were due to diseases other than AIDS, the majority being cancers. Lung cancer is the most common in terms of both incidence and mortality. It shows specific features when compared to the general population: there is an excess risk due to heavy smoking but also probably due to immunosuppression. The age of onset is younger and the prognosis worse than in the general population. Management is difficult, partly due to the aggressive nature of the tumor and partly to co-morbidities and potential interactions between anticancer and antiretroviral therapies. A phase II therapeutic trial (IFCT-CHIVA 1001) is under way nationally.

journal_name

Rev Mal Respir

authors

Lavolé A,Toper C,Belmont L,Ruppert AM,Wislez M,Cadranel J

doi

10.1016/j.rmr.2013.07.009

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

133-41

issue

2

eissn

0761-8425

issn

1776-2588

pii

S0761-8425(13)00246-5

journal_volume

31

pub_type

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