Abstract：
:An analysis of the way the pharyngeal musculature modulates the caliber of the pharynx is important to better understand and treat obstructive sleep apnea syndromes. The caliber of the pharynx at the soft palate depends on the action of the tensor veli, the palatoglossus, the palatopharyngeus and the uvula muscles. At the ligual level, the action of the genioglossus and the geniohyoideus predominate. These different muscle groups contract in co-ordination before the diaphragm contracts. Their activity is diminished and disorganized during sleep. These muscles appears to have a histological composition adapted to short-duration intense contractions making them vulnerable to fatigue. In apneic patients, these muscles are solicited constantly. Muscular lesions related to overwork have been suggested. The histological composition of these muscles is modified in apneic patients compared with non-apneic subjects (increased number of type IIa fibres), the expression of an adaptive process. The degree of adaptation varies depending of the pharyngeal level considered. Similar to their reflex stimulation, the response of these pharyngeal muscles to increased resistance is probably greater at the soft palate level. Greater solicitation of palatine muscles associated with their greater vulnerability to fatigue could explain why obstruction is particularly important at this level. A study of the mechanical and histological properties of the pharyngeal musculature is required for a better understanding of the occlusive mechanisms of the upper airways and must be undertaken before initiating therapeutic stimulation of these muscles.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Fleury Bsubject
Has Abstractpub_date
1999-02-01 00:00:00pages
51-6issue
1eissn
0761-8425issn
1776-2588pii
MDOI-RMR-02-1999-16-1-0761-8425-101019-ART51journal_volume
16pub_type
杂志文章,评审abstract：INTRODUCTION:Spinal metastases of lung cancer occur frequently and lead to the risk of spinal cord compression. Our objective is to clarify the management of this disease, emphasizing, in particular the use of prognostic scores. BACKGROUND:The first step is to evaluate the characteristics of the spinal lesion and its ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2012.12.016
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:The management of COPD aims to improve integrated indices such as health-related quality of life (HRQoL). Experts recommend repeated and methodical assessment of HRQoL, particularly by the use of questionnaires. Though these tools give pertinent information for groups of patients, they have limitations in des...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2010.03.020
更新日期：2010-05-01 00:00:00
abstract：:Invasive pulmonary aspergillosis is an opportunistic pneumonia which is particularly common in immuno-depressed subjects. The most frequent risk factors are the intensity and duration of leucopaenia, cytotoxic drugs and steroid therapy. In the respiratory tract, the proliferation of Aspergillus fumigatus becomes possi...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1988-01-01 00:00:00
abstract：INTRODUCTION:The aim of our study was to examine the practices and performance of a team working in a respiratory unit concerning the palliative care of patients with COPD, in a group of patients who died in hospital as a result of their disease. METHODOLOGY:The first step was focused on those patients who died in the...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2012.04.010
更新日期：2012-11-01 00:00:00
abstract：:The implication of "slow reacting substance of Anaphylaxis" SRS-A in the pathogenesis of asthma was realised in 1950. In recent years SRS-A has been shown to be a mixture of varied composition: The Leukotrienes (LT) C4, D4 and E4. These substances derive their arachidonic acid through the 5-lipoxygenase. The LT B4, wh...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Inhaled corticosteroid is the first choice antiinflammatory therapy for chronic asthma. International guidelines are based upon data obtained in the non-smokers with asthma. The objective of this review is to highlight the interaction between cigarette smoking and metabolism of steroids and to consider the consequence...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/s0761-8425(08)71516-x
更新日期：2008-02-01 00:00:00
abstract：:Bronchiolitis obliterans organizing pneumonia (BOOP) is defined by endoluminal obstruction of distal airspaces by a fibrous granulation tissue consisting of inflammatory cells, fibroblasts, and connective tissue. The morphogenesis of the process is the following: diffuse alveolar injury leading to basement membrane de...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：:The occurrence is reported of a bronchial epidermoid cancer appearing 13 years after irradiation for an intra-thoracic paraganglioma. Four criteria are required when considering the carcinogenic effects of radiation: a documented history or irradiation, a latent period of 8 to 20 years, histological evidence of the de...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:Patients with clinical stage IIIAN2 non-small cell lung cancer (NSCLC) are a heterogeneous subgroup in term of prognosis and therapeutic management. The optimal management of this patient group is a major focus for thoracic oncology research and the concept of multimodality treatment has recently been introduced. This...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2011.05.017
更新日期：2012-02-01 00:00:00
abstract：:We report the observation of a 78 year old patient who had a plexiform ameloblastoma since the age of 38. A systematic pulmonary radiographic examination revealed multiple dense nodules like "cannon ball secondaries". However the histology of these pulmonary nodules, obtained by open lung biopsy, was identical with th...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：INTRODUCTION:We report a case of extensive pulmonary nocardiosis in a patient infected with HIV. CASE REPORT:It presented as bilateral cavitated masses and bulky necrotic mediastinal lymphadenopathy causing broncho-oesophageal fistulae. There was associated infection with Mycobacterium Avium. There was satisfactory pr...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(04)71247-4
更新日期：2004-02-01 00:00:00
abstract：INTRODUCTION:Intensivists are increasingly implementing end-of-life decisions in patients who remain dependent on life sustaining therapies without hope for recovery. STATE OF THE ART:Descriptive studies have provided epidemiological data on ICU end-of-life care, identifying areas for improvement. Qualitative studies ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2006-09-01 00:00:00
abstract：:We report seven cases of seven pulmonary varicella occurring in seven adults without any previous history of known immunological deficit. In all the cases the vesicular eruption was diffuse, occurring after contact with a child presenting with benign varicella. The respiratory signs appeared five to seven days after t...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：INTRODUCTION:The anti-Hu associated syndrome is a rare paraneoplastic neurological syndrome, which is principally associated with small-cell lung cancer. OBSERVATION:We report the case of a patient with the following clinical features: dysautonomia with severe gastroparesis, sensory neuropathy and a rhombencephalitis....
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2010.02.006
更新日期：2010-03-01 00:00:00
abstract：INTRODUCTION:Alpha-1 antitrypsin deficiency is a hereditary disease defined at the biological level by a serum alpha-1 antitrypsin level below 11μM/L. The null variants are characterized by undetectable circulating alpha-1 antitrypsin levels. Suspicion of a null variant requires the use of appropriate diagnostic techni...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2015.10.007
更新日期：2016-09-01 00:00:00
abstract：:Bradykinin and related kinins formed in tissues and fluids during inflammation, exert many physiological effects mediated by two receptor subtypes: B1 and B2. The involvement of kinins in bronchial asthma has been speculated in numerous clinicals reports. The effects of bradykinin on airways have been studied in vivo ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：:Numerous types of cells have a capacity for movement in physiological or pathological situations. For example, this is the case for inflammatory cells in the lung, during acute lobar pneumonia, sarcoidosis and idiopathic pulmonary fibrosis. Cellular migration is a general process which rests on the interaction between...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：AIM:To our knowledge, the proportion of active tuberculosis diagnosed after 12-18 months during a screening tuberculosis process in a specialized centre (centre de lutte antituberculeuse [CLAT]) has not been described in France. The majority of other countries do not have any recommendation to screen at this time. MET...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2014.06.031
更新日期：2015-09-01 00:00:00
abstract：:Acquired hemophilia A (AHA) is a rare disease, defined by the production of anti-factor VIII antibodies causing disordered hemostasis. It is idiopathic in 50% of cases, but sometimes associated with solid tumors. We report a case where AHA led to the diagnosis of lung cancer. CASE REPORT:An 82-year-old man with spont...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2017.08.005
更新日期：2018-09-01 00:00:00
abstract：INTRODUCTION:Lung hyperinflation (LH) has become a major concern in the management of chronic obstructive pulmonary disease (COPD). MAIN AIM:To evaluate the role of lung volumes in the positive diagnosis of COPD and in the assessment of airway obstruction reversibility. POPULATION AND METHODS:Three hundred and sixty-...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2013.05.009
更新日期：2014-01-01 00:00:00
abstract：:Pleurisies due to the syndrome of ovarian hyperstimulation typically accompany ascites and in their most severe form are associated with haemoconcentration, hypovolaemia and thromboembolic phenomena. It is not unusual in this context for pleural effusions to be isolated. They may occur during treatment for sterility b...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The consensus conference convened by the French Language Society for Infectious Disease at Lille in 1991 stressed the fact that two germs were most often the cause of exacerbation in chronic bronchitis (Streptococcus pneumoniae and Haemophilus influenzae) and that antibiotic therapy was the "safe solution" and that th...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：INTRODUCTION:Lung neuroendocrine large-cell carcinoma (LNELCC) is a rare tumour with a poor prognosis. There are very few guidelines for LNELCC treatment but a better knowledge of its biology could improve the treatment and prognosis of this malignancy. OBSERVATIONS:We present the cases of 2 patients who presented ini...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2016.05.010
更新日期：2017-01-01 00:00:00
abstract：:Pollinosis is now called seasonal allergic rhinitis by the international terminology but pollinosis includes many other symptoms and so we will use the term Ambrosia pollinosis in this article. The characteristics of ragweed pollinosis are: severity, duration from August to September and the presence of asthma and/or ...
journal_title：Revue des maladies respiratoires
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.rmr.2012.10.632
更新日期：2013-04-01 00:00:00
abstract：INTRODUCTION:Pleural effusions are common in ICU patients. Causes include massive fluid resuscitation in shock, pneumonia--either community acquired or nosocomial, cardiac insufficiency, hypoalbuminemia and hepatic impairment. Pleural effusions frequently complicate cardiac and abdominal surgery and haemothorax may com...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/s0761-8425(05)85438-5
更新日期：2005-02-01 00:00:00
abstract：INTRODUCTION:Patients suffering from sarcoidosis sometimes report dyspnoea of effort. The restrictive or obstructive ventilatory problems contribute to this disability, but the systemic manifestations of sarcoidosis should be considered as other possible causes of the dyspnoea. CASE REPORT:We report a case of systemic...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：INTRODUCTION:Exercise testing is useful in the respiratory evaluation of patients with cystic fibrosis. The shuttle walk test (SWT) is a progressive, externally paced, exercise test requiring the subject to walk/run back and forth between two fixed points. The aim is to assess the reproductibility of the SWT in paediat...
journal_title：Revue des maladies respiratoires
pub_type： 临床试验,杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：:We report a case of eosinophilic pneumonia secondary to taking Tetracycline whose severity required the use of mechanical ventilation and steroid therapy. On the basis of this case, we review the characteristics of drug-induced pneumonia as well as the differential diagnosis which are evoked. ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:The authors describe a case of drug-induced cytolytic hepatitis probably secondary to hypersensitivity to allopurinol which was prescribed incorrectly for secondary hyperuricaemia during treatment with pyrazinamide. The diagnosis was reviewed in view of the late occurrence of hepatitis in relation to the onset of the ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：INTRODUCTION:Whereas numerous case reports have described statin-induced lung injuries, statin-induced pleural effusions are uncommon. CASE REPORT:An 84-year-old man presented with bilateral pleural effusions two years after starting treatment with atorvastatin. No other cause of pleural effusion was found and all sym...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2015.12.010
更新日期：2016-09-01 00:00:00
