[Small cell lung cancer and anti-Hu syndrome].

Abstract:

INTRODUCTION:The anti-Hu associated syndrome is a rare paraneoplastic neurological syndrome, which is principally associated with small-cell lung cancer. OBSERVATION:We report the case of a patient with the following clinical features: dysautonomia with severe gastroparesis, sensory neuropathy and a rhombencephalitis. Tumour regression was obtained with chemotherapy but the patient ultimately died from the neurological complications. CONCLUSION:Neurological syndromes associated in small cell lung cancer with anti-Hu antibodies are very diverse. Cancer evolution is generally speaking more benign than usual with the prognosis linked to the severity of the neurological involvement.

journal_name

Rev Mal Respir

authors

Prim N,Mennecier B,Behr C,Fraisse P,Echaniz-Laguna A,Tranchant C,Quoix E

doi

10.1016/j.rmr.2010.02.006

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

261-5

issue

3

eissn

0761-8425

issn

1776-2588

pii

S0761-8425(10)00124-5

journal_volume

27

pub_type

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