Abstract：
:The implication of "slow reacting substance of Anaphylaxis" SRS-A in the pathogenesis of asthma was realised in 1950. In recent years SRS-A has been shown to be a mixture of varied composition: The Leukotrienes (LT) C4, D4 and E4. These substances derive their arachidonic acid through the 5-lipoxygenase. The LT B4, which is not conjugated to glutathione (as compared to LT C4, D4 and E4) possesses powerful chemotactic activity and an (indirect) contractile effect on smooth muscle. LTC4, D4, E4 in vitro and in vivo, both by inhalation or intravenously, are powerful bronchoconstrictors clearly superior to histamine. The effects of C4 and LTD4 predominantly affect the peripheral airways.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Leitch AGsubject
Has Abstractpub_date
1984-01-01 00:00:00pages
329-36issue
6eissn
0761-8425issn
1776-2588journal_volume
1pub_type
杂志文章abstract：INTRODUCTION:Exercise testing is useful in the respiratory evaluation of patients with cystic fibrosis. The shuttle walk test (SWT) is a progressive, externally paced, exercise test requiring the subject to walk/run back and forth between two fixed points. The aim is to assess the reproductibility of the SWT in paediat...
journal_title：Revue des maladies respiratoires
pub_type： 临床试验,杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：INTRODUCTION:Breath-hold diving has been practised since the dawn of humanity but is open to many risks. The consequences mainly involve the respiratory system. The pathophysiological mechanisms are complex because of the multiple forces applied to the body during breath-hold diving. OBSERVATION:The case reported here...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(07)74263-8
更新日期：2007-11-01 00:00:00
abstract：:We report on a 45-year old woman with daytime sleepiness, polycythemia, hypoxemia and hypercapnia, admitted to hospital on three occasions in a 10 month period for acute respiratory failure. Polysomnography demonstrated apneas of central type, testing of the respiratory drive suggested central alveolar hypoventilation...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:There is no standard second-line treatment for small cell lung cancer (SCLC). The prognosis of these patients is poor and special attention should be paid to both quality of life and economic factors. METHODS:The aim of this phase II randomised trial (GFPC0501) is to compare, in patients with progressive SC...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/s0761-8425(07)91136-5
更新日期：2007-05-01 00:00:00
abstract：INTRODUCTION:The anti-Hu associated syndrome is a rare paraneoplastic neurological syndrome, which is principally associated with small-cell lung cancer. OBSERVATION:We report the case of a patient with the following clinical features: dysautonomia with severe gastroparesis, sensory neuropathy and a rhombencephalitis....
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2010.02.006
更新日期：2010-03-01 00:00:00
abstract：INTRODUCTION:Cancer and venous thromboembolism are frequently associated. STATE OF THE ART:Venous thromboembolism is associated with a worse prognosis in patients with cancer. Thrombosis in cancer patients is related to the expression of tissue factor and other procoagulants by tumour cells. Surgery, chemotherapy and ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2011.02.007
更新日期：2011-04-01 00:00:00
abstract：INTRODUCTION:In France, long-term follow-up after occupational exposure to asbestos is recommended. This study looked at the psychological consequences in the longer term following a CT-scan, in particular the impact of having received compensation for an occupational disease. METHODS:As part of an asbestos post-expos...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2019.06.009
更新日期：2019-10-01 00:00:00
abstract：:Excessive widening of the alveolar-arterial gradient for oxygen, with respect to the subject's age and oxygen uptake, is the most sensitive signal of a disturbance in pulmonary gas exchange, whether it is due to ventilation, circulation or diffusion. During incremental exercise, simultaneous measurements of metabolic ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2012.05.018
更新日期：2012-12-01 00:00:00
abstract：:Nowadays the diagnosis of pulmonary embolism (PE) is based on a "diagnostic strategy" rather than a single test. The first step, after identifying patients with suspicion of PE, is to establish the pre-test clinical probability. Several scores are available to make a standardised and reproducible assessment of the cli...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2010.10.039
更新日期：2011-06-01 00:00:00
abstract：INTRODUCTION:Synovial sarcoma is an uncommon tumour and thoracic involvement is rare and of varying location. Clinical characteristics are dominated by pain, with a slow progression over years. Pathological and immuno-histochemical characteristics are helpful in the diagnosis but a specific translocation between chromo...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2009.11.006
更新日期：2010-01-01 00:00:00
abstract：:The authors report a case of a patient presenting with a bronchogenic mediastinal cyst, which presented as a super-infection of the cyst. The cyst was associated with malformation of the cervical vertebra, cardiovascular abnormalities and congenital deafness, placing this in the group of rare complex polymalformation ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVES:To report the results of minimally invasive surgery in patients with stage I or II thymoma in the Masaoka classification. The reference technique is partial or complete thymectomy by sternotonomy. METHODS:A retrospective single-center study of a prospective database including all cases of thymoma operated f...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2017.01.002
更新日期：2017-05-01 00:00:00
abstract：:The purpose of this study was to investigate the utility of 18fluorodeoxyglucose (FDG) coincidence detection position emission tomography (CDET) in the evaluation of metastatic mediastinal lymph nodes in patients with potentially operable non-small-cell lung cancer (NSCLC). A prospective study was performed in thirty ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:General reviews about occupational asthma divide the susceptible allergens capable of initiating asthma into two distinct groups: those of high and of low molecular weight. Atopy would be a risk factor for developing occupational asthma to high molecular weight allergens but not to those of low molecular weight. In th...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:Thirteen patients with a tracheostomy who were undergoing artificial ventilation at home were included in a study covering 62 episodes, during a month of treatment, which was undertaken with three different humidification systems: A Puritan Bennet Cascade humidifier (C), a Swedish nose Vygon-(V) (a hydroscopic condens...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：INTRODUCTION:Aeromonas pneumonia associated with near-drowning, though uncommon, is serious and a major morbidity factor for patients. CLINICAL CASE:A healthy 30-year-old man nearly drowned in a pound. He was admitted to the medical intensive care unit and required intubation and mechanical ventilation. He was given a...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2018.08.004
更新日期：2018-11-01 00:00:00
abstract：STATE OF THE ART:The IRAD2 trial is evaluating a 3-month home intervention which includes education, oral supplements, exercise and androgenic steroids in undernourished patients with chronic respiratory failure. The main objective is to increase the six-minute walking distance by more than 50 m with an improvement in ...
journal_title：Revue des maladies respiratoires
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0761-8425(04)71362-5
更新日期：2004-06-01 00:00:00
abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a common but under-diagnosed pathology in primary care. The objective was to study the feasibility of a randomized controlled trial in general practice to detect new cases of COPD at an earlier stage. METHODS:A cluster randomized, controlled, multicenter int...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.rmr.2018.08.023
更新日期：2019-02-01 00:00:00
abstract：:The measurement of non-allergic bronchial hyperreactivity brings limited information in the diagnosis of asthma, whether for epidemiological purposes or for an individual patient. Its sensitivity and specificity in the general population amount to 46 and 89% respectively. It follows that the positive and negative pred...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：INTRODUCTION:The major obstacle to long-term survival after lung transplantation is chronic graft rejection (CR) which is defined histologically by obliterative bronchiolitis (OB). STATE OF THE ART:The causes of post-transplant OB are not fully understood, but there is evidence that this chronic process is influenced ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2003-04-01 00:00:00
abstract：:Primary malignant melanoma of the lower airways is very rare. 24 cases have been collected over the past century. Our case was a patient of 52 years of age who had been discovered to have a tracheal tumour which was found to be a malignant melanoma and was treated with a Laser. The major problem is to establish that t...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：INTRODUCTION:Spinal metastases of lung cancer occur frequently and lead to the risk of spinal cord compression. Our objective is to clarify the management of this disease, emphasizing, in particular the use of prognostic scores. BACKGROUND:The first step is to evaluate the characteristics of the spinal lesion and its ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2012.12.016
更新日期：2013-06-01 00:00:00
abstract：:An experimental model of lung obstruction has been achieved in the cat reared in our laboratory. 30 young adults (J) and one adult subject (A) had tracheal stenosis from 8 to 15 weeks and were the object of a study of pulmonary airways and were compared with four young controls and seven older controls. The presence o...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Surgery is the current standard treatment of early-stage non-small cell lung cancer (stage I and II tumors). Contrary to adjuvant chemotherapy, which was recently demonstrated to decrease systemic tumor recurrences as well as increasing overall survival, postoperative radiotherapy did not benefit from an actualized ev...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2008-10-01 00:00:00
abstract：:A 28-year-old girl suffering from lysinuric protein intolerance was referred on account of severe chronic respiratory failure. Since childhood she had failure to thrive with chronic hyperammonaemia and interstitial lung disease but normal respiratory function. At the age of 21, she experienced haemoptysis and worsenin...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2010.06.022
更新日期：2010-09-01 00:00:00
abstract：:Bronchial provocation tests are useful for the detection of subclinical bronchial hyper-reactivity. Their standardisation is vital, in particular the method of administration of the bronchoconstrictor agent. Our study compares two systems of histamine delivery: an aerosol propellant with freons and a jet nebuliser lin...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：INTRODUCTION:The number of lung transplantations performed is increasing worldwide. With an improved experience and outcomes, the age of the recipient on its own has ceased to be an absolute contra-indication. We report our first experience with lung transplantation in patients aged 65 years or older. METHODS:From Jan...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2020.08.012
更新日期：2020-12-01 00:00:00
abstract：:The phospholipid content of bronchoalveolar lavage (LBA) has been little studied till now. This work involved 96 LBA on 7 cases of allergic alveolitis, 11 cases of diffuse interstitial fibrosis (FID) and 42 of sarcoidosis. The liquid collected was submitted to a cellular study (cellularity, total and differential) and...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The authors report a case of a ruptured right subphrenic abscess causing a diffuse peritonitis complicating a chronic empyema. The authors recommend active treatment of purulent pleurisies, particularly when they are associated with a bronchopleural fistula. ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：:Amongst the elements which contributed to the success of the early lung transplants at the beginning of the 1980's we feel that the careful selection of candidates probably played a predominant role. If some of the selection criteria initially described remain somewhat intangible, others have either been eased or have...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
