[Targeted screening of COPD in primary care: Feasibility and effectiveness].

Abstract:

INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a common but under-diagnosed pathology in primary care. The objective was to study the feasibility of a randomized controlled trial in general practice to detect new cases of COPD at an earlier stage. METHODS:A cluster randomized, controlled, multicenter intervention study comparing, according to a 2×2 factorial plan, two case finding strategies: a systematic GOLD-HAS hetero-questionnaire and coordination of the patient's path to facilitate access to spirometry. The PIL-DISCO pilot study took place in 2017. Patients between 40 and 80 years old, with no previous history of COPD, consulting their GP on a given day regardless of the reason, were included. RESULTS:176 patients were included in 1.5 days. Spirometry was performed in none of the control arm, in 13 (29.5%) of the questionnaire arm, in 22 (50%) in the coordination arm and in 32 (72.7%) with the combination of the two strategies. Two cases of stage 2 COPD and thirteen other respiratory diseases were diagnosed. CONCLUSIONS:This study confirms the feasibility of the protocol in primary care in terms of speed of inclusion and acceptability. An extension phase aiming to include 3200 patients will assess the diagnostic value of the two strategies tested in general practice.

journal_name

Rev Mal Respir

authors

Chapron A,Pelé F,Andres É,Fiquet L,Laforest C,Veislinger A,Fougerou C,Turmel V,Fouchard J,Yourish B,Oumari S,Allory E,Banâtre A,Schweyer FX,Pommier J,Brinchault G,Guillot S,Laviolle B,Jouneau S

doi

10.1016/j.rmr.2018.08.023

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

162-170

issue

2

eissn

0761-8425

issn

1776-2588

pii

S0761-8425(18)30977-X

journal_volume

36

pub_type

杂志文章,多中心研究,随机对照试验
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  • [Management of wheezing disorders in infants participating in the PARIS birth cohort].

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    authors: Depagne C,Nesme P,Pérol M,Guérin JC

    更新日期:1999-11-01 00:00:00

  • [Attitude of private pharmacists in the dispensation of asthma drugs].

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  • [Is the asthmatic patient competent to manage his disease? A study of 280 patients in Seine-Saint-Denis, France].

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    pub_type: 杂志文章

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  • [Respiratory resuscitation in Quebec. General aspects and implications of pneumologists in intensive care units in "New France"].

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    doi:

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  • [Digital action plan for asthma exacerbations (PANAME)].

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    journal_title:Revue des maladies respiratoires

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.rmr.2016.10.881

    authors: Beydon N,Delclaux C,Groupe PANAME.

    更新日期:2017-11-01 00:00:00

  • [Radiological screening for lung cancer].

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    journal_title:Revue des maladies respiratoires

    pub_type: 杂志文章,评审

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    authors: Lemarié E

    更新日期:2005-12-01 00:00:00

  • [Lipid pneumonia and superinfection by Mycobacterium fortuitum. Apropos of a case].

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    journal_title:Revue des maladies respiratoires

    pub_type: 杂志文章

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    更新日期:1987-01-01 00:00:00

  • [Pulmonary metastasis of an ameloblastoma].

    abstract::We report the observation of a 78 year old patient who had a plexiform ameloblastoma since the age of 38. A systematic pulmonary radiographic examination revealed multiple dense nodules like "cannon ball secondaries". However the histology of these pulmonary nodules, obtained by open lung biopsy, was identical with th...

    journal_title:Revue des maladies respiratoires

    pub_type: 杂志文章

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    更新日期:1985-01-01 00:00:00

  • [Metalloproteinases in the extracellular matrix: structure and activity].

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    pub_type: 杂志文章,评审

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    authors: Cuvelier A,Kuntz C,Sesboüé R,Muir JF,Martin JP

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  • [Epidermoid bronchial cancer induced by radiotherapy].

    abstract::The occurrence is reported of a bronchial epidermoid cancer appearing 13 years after irradiation for an intra-thoracic paraganglioma. Four criteria are required when considering the carcinogenic effects of radiation: a documented history or irradiation, a latent period of 8 to 20 years, histological evidence of the de...

    journal_title:Revue des maladies respiratoires

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    doi:

    authors: de Crevoisier R,le Cesne A,le Chevalier T

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  • [Mucoviscidosis: current diagnostic possibilities. Applications in perinatology].

    abstract::The gene of cystic fibrosis is localised on the long arm of chromosome 7. DNA probes placed close to the gene enable a study of restriction polymorphism to follow the transmission of the gene in index families. It is now possible to counsel those families, who already have an affected child, with an early antenatal di...

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    authors: Ferec C,Chabaud JJ,Parent P,Dewitte JD,Verlingue C,Clavier J,Saleun JP

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  • [Acute eosinophilic pneumonia and the larva migrans syndrome: apropos of a case in an adult].

    abstract::Toxocariasis is a frequent disease in children, but the severe clinical manifestations are rare in the literature (diffuse interstitial pneumonia with hypoxaemia and acute severe asthma). The diagnosis is made thanks to the reliability of serological techniques (the ELISA test and using antigen excretion-secretion tes...

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    doi:

    authors: Bouchard O,Arbib F,Paramelle B,Brambilla C

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  • [Study of forced expiratory flow rates in respiratory paralysis].

    abstract::Subjects with a complete paralysis of the abdominal muscles and severe or lesser involvement of the intercostals were studied. The author analysed, under electromyographic control, the flow-volume curves by measuring flow at 50% (V50) and at 25% (V25) of the observed and theoretical vital capacity (CV) above observed ...

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    doi:

    authors: Leroy M,Jaeger-Denavit O,Liot F

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  • [Clinical investigation of diaphragmatic function. Relationships with the biology of muscle].

    abstract::Diaphragmatic strength, which can be roughly estimated by non invasive techniques such as maximal inspiratory pressure or sniff nasal pressure, is specifically assessed by the measurement of transdiaphragmatic pressure during electric or magnetic phrenic nerve stimulation. However, muscle endurance is probably a more ...

    journal_title:Revue des maladies respiratoires

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    doi:

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    更新日期:2000-06-01 00:00:00

  • [Retrospective analysis of 50 thymic epithelial tumors in Rennes university hospital].

    abstract:BACKGROUND:Thymic epithelial tumors (TET), including thymomas and thymic carcinomas, are rare and characterized by very different evolutionary patterns depending on histology and invasion stage. The therapeutic management is not well defined but is a subject of increasing interest. The descriptive and analytic objectiv...

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  • [Lung neuroendocrine large-cell carcinoma in young women - An unusual presentation].

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    pub_type: 杂志文章

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    authors: Proux A,Greillier L,Barlesi F,Tomasini P

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  • [Surgical management and outcomes of lung cancer in women - results from the Epithor database].

    abstract:INTRODUCTION:Rates of lung cancer in women have been increasing continually for several years. The basic surgical management of this condition is the same in both sexes but a number of differences are apparent. METHODS:We analysed data entered onto the Epithor database between June 2002 and June 2006 concerning 8535 s...

    journal_title:Revue des maladies respiratoires

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    doi:10.1016/s0761-8425(07)91390-x

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    doi:10.1016/j.rmr.2010.02.006

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  • [Prescription of asthma action plans in the Aquitaine region of France].

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    更新日期:2008-02-01 00:00:00

  • [Anaesthesia for bronchial echoendoscopy: experience with the laryngeal mask].

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  • [Skin sensitisation profiles of outpatients with symptoms of respiratory allergies].

    abstract:AIM:The main objective of the survey was to determine the frequency of the mono and polysensitizations in patients consulting for respiratory allergy, rhinitis or/and asthma. The secondary objectives were to evaluate the severity, the number and the type of the sensitizations, the frequency of the asthma or rhinitis as...

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  • [Corticoid therapy and bronchial inflammation in asthma. The use of bronchial biopsy].

    abstract::The development of fibreoptic bronchoscopy has enabled significant progress in the understanding of the pathogenesis of asthma. It has brought to the fore the importance of bronchial inflammation even in asymptomatic patients and/or in patients who have only mild disease. The practice of bronchial biopsy in vivo is an...

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    doi:

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  • [Unusual pulmonary presentation of lysinuric protein intolerance].

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  • [Screening for bronchial carcinoma].

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    doi:

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