[Perioperative treatment for resected non-small cell lung cancer: Which option in 2020?]

Abstract:

:Surgery is the ultimate curative treatment for resectable non-small cell lung cancer (NSCLC). However, the prognosis for operated patients remains disappointing. Multiple randomized studies have shown that administering perioperative chemotherapy improves the prognosis and increases the cure rate by around 3-5%. The purpose of this article is to take stock of the role of perioperative treatments for NSCLC, which can be completely resected. Six questions were evaluated: 1) What is the place of (neo) adjuvant chemotherapy in 2020, among others in the early stages (IB)? 2) Can new chemotherapy agents be combined with a platinum derivative? 3) What is the place of radiochemotherapy for resectable NSCLC? 4) Is there a place for postoperative radiotherapy (PORT)? 5) Is there a place for targeted therapies for resectable NSCLC? 6) What is the place of immunotherapies in the perioperative period?

journal_name

Rev Mal Respir

authors

Coureau M,Berghmans T

doi

10.1016/j.rmr.2020.12.002

subject

Has Abstract

pub_date

2021-01-01 00:00:00

pages

74-86

issue

1

eissn

0761-8425

issn

1776-2588

pii

S0761-8425(20)30382-X

journal_volume

38

pub_type

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