Abstract:
:Surgery is the ultimate curative treatment for resectable non-small cell lung cancer (NSCLC). However, the prognosis for operated patients remains disappointing. Multiple randomized studies have shown that administering perioperative chemotherapy improves the prognosis and increases the cure rate by around 3-5%. The purpose of this article is to take stock of the role of perioperative treatments for NSCLC, which can be completely resected. Six questions were evaluated: 1) What is the place of (neo) adjuvant chemotherapy in 2020, among others in the early stages (IB)? 2) Can new chemotherapy agents be combined with a platinum derivative? 3) What is the place of radiochemotherapy for resectable NSCLC? 4) Is there a place for postoperative radiotherapy (PORT)? 5) Is there a place for targeted therapies for resectable NSCLC? 6) What is the place of immunotherapies in the perioperative period?
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Coureau M,Berghmans Tdoi
10.1016/j.rmr.2020.12.002subject
Has Abstractpub_date
2021-01-01 00:00:00pages
74-86issue
1eissn
0761-8425issn
1776-2588pii
S0761-8425(20)30382-Xjournal_volume
38pub_type
杂志文章,评审abstract::We report a case of eosinophilic pneumonia secondary to taking Tetracycline whose severity required the use of mechanical ventilation and steroid therapy. On the basis of this case, we review the characteristics of drug-induced pneumonia as well as the differential diagnosis which are evoked. ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND:The natural history and optimal therapeutic management of emphysema associated with alpha-1 antitrypsin deficiency are poorly understood. The purpose of this cohort of patients with emphysema associated with alpha-1 antitrypsin deficiency is to describe their characteristics and to study the factors associat...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,多中心研究
doi:10.1019/200530093
更新日期:2005-12-01 00:00:00
abstract:INTRODUCTION:Aeromonas pneumonia associated with near-drowning, though uncommon, is serious and a major morbidity factor for patients. CLINICAL CASE:A healthy 30-year-old man nearly drowned in a pound. He was admitted to the medical intensive care unit and required intubation and mechanical ventilation. He was given a...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2018.08.004
更新日期:2018-11-01 00:00:00
abstract::Since 1975, 340 patients were treated by tracheal sleeve resection for tracheal or subglottic laryngeal iatrogenic stenoses in our unit. Preoperative iterative Nd YAG laser sessions have usually been performed, without success. The length of the sleeve specimen was an average of 3 1/4 cm. Twelve patients died on the p...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::The occurrence is reported of a bronchial epidermoid cancer appearing 13 years after irradiation for an intra-thoracic paraganglioma. Four criteria are required when considering the carcinogenic effects of radiation: a documented history or irradiation, a latent period of 8 to 20 years, histological evidence of the de...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::We report two cases of paratracheal cystic tumors where no preoperative diagnosis could be established. Mediastinoscopy provided the diagnosis of pleuropericardial cyst. The mediastinoscopic approach allowed partial removal in one case and complete removal in the other. ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00
abstract::The long term outcome for 88 patients with bullous emphysema who had operations was analysed from the clinical, respiratory function and occupational point of view. In order to reduce to the minimum any bias which would be likely to appear as a result of a decrease in the number of patients with time respiratory funct...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The matrix metalloproteinases (MMP) are a multigenic family involving 14 enzymes which can cleave most, if not all, the components of the extracellular matrix (interstitium and basement membranes). The present work reports on the main structural characteristics, the substrate preference and the site synthesis of these...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract::60 patients were studied with severe chronic respiratory failure (IRC) and a permanent tracheostomy treated with domiciliary ventilation (VADT). The study commenced from the time of the tracheostomy and included length of survival (by the actuarial method) quality of life, subjectively and objectively (progress of blo...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:INTRODUCTION:The aim of the article is to present a summary of current knowledge on tobacco smoking in France available through representative population surveys. STATE OF ART:Smoking is very common in France as more than a quarter (28.7%) of 15-75years old individuals reported daily smoking in 2016. The rate is also ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2018.01.008
更新日期:2018-06-01 00:00:00
abstract::Inhaled corticosteroid is the first choice antiinflammatory therapy for chronic asthma. International guidelines are based upon data obtained in the non-smokers with asthma. The objective of this review is to highlight the interaction between cigarette smoking and metabolism of steroids and to consider the consequence...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/s0761-8425(08)71516-x
更新日期:2008-02-01 00:00:00
abstract::The aim of this work was to study the kinetic of intramacrophage penetration of cotrimoxazole in guinea pigs which had received 100 mg/kg of sulfamethoxazole and 20 mg/kg of trimethoprim after a single intraperitoneal injection. 30 minutes, 1, 3, 6 and 24 hours after this injection an intra-cardiac blood sample was ta...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Right ventricular failure (RVF) is a common cause of admission to the intensive care unit and its presence is a major prognostic factor in acute pulmonary embolism (PE) and chronic pulmonary hypertension (PH). RVF results from an incapacity of the RV to adapt to an increase in afterload so it can become critical in ac...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2019.07.012
更新日期:2020-02-01 00:00:00
abstract::Severe asthma required high dose of corticosteroids combined with biotherapies to control more or less asthma symptoms and lead to the decrease of patients' quality of life on long term. Recent studies show that hypoallergenic peptides derived from allergen can prevent airway hyperresponsiveness, decrease Th2 response...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2019.03.005
更新日期:2019-04-01 00:00:00
abstract::The imaging techniques used to investigate patients with asthma and to assess the effects of asthma treatments include computed tomography (CT), helium magnetic resonance imaging (MRI), single-photon emission computed tomography (SPECT), and positron-emission tomography (PET). Only MRI does not involve radiation expos...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2011.05.001
更新日期:2011-06-01 00:00:00
abstract::Pleurisies due to the syndrome of ovarian hyperstimulation typically accompany ascites and in their most severe form are associated with haemoconcentration, hypovolaemia and thromboembolic phenomena. It is not unusual in this context for pleural effusions to be isolated. They may occur during treatment for sterility b...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Busulfan or Misulban is considered by many the treatment of choice in chronic myeloid leukemia, for which it is used as a single agent. An interstitial fibrosing lung disease occurring after Busulfan was first described in 1961 and to date 56 cases have been published and are the object of this review. The clinical pi...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::The phospholipid content of bronchoalveolar lavage (LBA) has been little studied till now. This work involved 96 LBA on 7 cases of allergic alveolitis, 11 cases of diffuse interstitial fibrosis (FID) and 42 of sarcoidosis. The liquid collected was submitted to a cellular study (cellularity, total and differential) and...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract:INTRODUCTION:The nerve growth factor (NGF) is known as a factor involved in neuronal growth and survival. From recent studies it may also be considered as a mediator of inflammation, in particular in the airways. STATE OF ART:Several animal studies have shown that NGF may increase the sensory innervation, and particip...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/s0761-8425(04)71290-5
更新日期:2004-04-01 00:00:00
abstract::The authors report the results of a multi-centre trial on 500 cases of lymph-epithelial thymoma (TLE) treated by 14 surgical teams. Most typically a tumour of the adult in the fifth decade, occurring most commonly in women (60%), one in every two cases of TLE occurs in auto-immune disease: usually myasthenia. Most oft...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Clinical data support the hypothesis that aggressivity is inhibited amongst asthmatics. The relationship of violence, as a marker of aggressiveness, to asthma was examined in a population-based sample of 12.466 students of secondary schools in France (Enquête sur la Santé de l'adolescent 1993/1994) using an epidemiolo...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract:INTRODUCTION:The main aim of this study is to evaluate the effectiveness of preventive actions regarding influenza in the studied populations. The secondary objective is to analyze and understand the mechanisms which bring about a behavioural change regarding influenza vaccination. METHODS:The interventional and prosp...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2017.11.003
更新日期:2018-03-01 00:00:00
abstract::Urinary antigen tests are quick and simple tests helping to provide an etiological diagnosis in community-acquired pneumonia. However, their prescription is sometimes excessive and performed in unjustified situations. The therapeutic benefit is limited. Indeed, studies show that appropriate antibiotic therapy based on...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2015.06.004
更新日期:2015-10-01 00:00:00
abstract:INTRODUCTION:To prevent and control chronic respiratory diseases, the WHO has outlined a programme to be applied in all the countries. In Sub-Saharan countries like Senegal, its application faces many barriers. METHODS:This work is a detailed analysis of the main areas of the programme based on the socio-economic, cul...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/s0761-8425(04)71352-2
更新日期:2004-06-01 00:00:00
abstract::Bronchiolitis obliterans organizing pneumonia (BOOP) is defined by endoluminal obstruction of distal airspaces by a fibrous granulation tissue consisting of inflammatory cells, fibroblasts, and connective tissue. The morphogenesis of the process is the following: diffuse alveolar injury leading to basement membrane de...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract:INTRODUCTION:Synovial sarcoma is an uncommon tumour and thoracic involvement is rare and of varying location. Clinical characteristics are dominated by pain, with a slow progression over years. Pathological and immuno-histochemical characteristics are helpful in the diagnosis but a specific translocation between chromo...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2009.11.006
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Lung hyperinflation (LH) has become a major concern in the management of chronic obstructive pulmonary disease (COPD). MAIN AIM:To evaluate the role of lung volumes in the positive diagnosis of COPD and in the assessment of airway obstruction reversibility. POPULATION AND METHODS:Three hundred and sixty-...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2013.05.009
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Evaluation of clinical practice in pulmonary oncology aims to improve both the quality of care and the control of costs. REVIEW OF THE LITERATURE:A Medline search of the literature allowed analysis of the published studies of the evaluation of clinical practice. They showed that though 82-95% of patients ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/s0761-8425(06)72080-0
更新日期:2006-12-01 00:00:00
abstract::We report the case of a 73 year old man presenting with severe hypoxaemia due to an anatomical right to left shunt from a persistent left superior vena cava (VCSG) anastomosing with the left auricle. This was fortuitously discovered while placing a left sub clavicular catheter; the diagnosis of the VCSG draining into ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Asbestos-related benign pleural lesions can involve the parietal pleura (pleural plaques), and/or visceral pleura as focal or diffuse (diffuse pleural thickening) fibrosis. Benign asbestos pleurisy and rounded atelectasis are linked with visceral pachypleuritis, the former as a cause, the latter as a consequence. The ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1999-12-01 00:00:00