[Dynamic lung hyperinflation and its clinical implication in COPD].

Abstract:

:Static lung hyperinflation is defined as the elevation of end- expiratory lung volume above its predicted value, with no increase in end-expiratory alveolar pressure, which remains equal to atmospheric pressure. Dynamic hyperinflation is the transient increase of this volume above the relaxation volume. In patients with COPD, dynamic hyperinflation is mainly determined by the mechanical properties of the respiratory system. Its measurement relies on plethysmography and, during exercise, inspiratory capacity. During exercise, dynamic hyperinflation attenuates expiratory flow limitation but increases the inspiratory loading and induces functional weakness of the diaphragm. It also has haemodynamic consequences and results in more rapid, shallow breathing and progressive reduction in dynamic lung compliance. These events explain exercise intolerance. Several approaches may help combat dynamic hyperinflation and its deleterious clinical effects: bronchodilators, hyperoxia, helium-oxygen mixtures, lung volume reduction surgery...

journal_name

Rev Mal Respir

authors

O'donnell DE

doi

10.1016/s0761-8425(08)75094-0

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

1305-18

issue

10

eissn

0761-8425

issn

1776-2588

pii

S0761-8425(08)75094-0

journal_volume

25

pub_type

杂志文章,评审
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  • [Bronchiolitis obliterans organizing pneumonia (BOOP). Characteristics and boundaries of an anatomo-clinical entity].

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    authors: Cordier JF,Loire R,Peyrol S

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  • [Bronchoscopy in the diagnosis of complicated pulmonary hydatid cyst in children].

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    doi:

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    doi:

    authors: Fleury B

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  • [Indications of bronchial endoscopy in suspected tracheo-bronchial foreign body in children].

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    journal_title:Revue des maladies respiratoires

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    doi:

    authors: Martinot A,Deschildre A,Brichet A,Leclerc F

    更新日期:1999-11-01 00:00:00

  • [Tobacco consumption of students ages 8 to 22 in Abidjan, 2002].

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    pub_type: 杂志文章

    doi:

    authors: Van Denhove A,Freymond N,Isaac S,Marrou K,Balme B,Gormand F,Guibert B,Pacheco Y,Devouassoux G

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    journal_title:Revue des maladies respiratoires

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    doi:10.1016/j.rmr.2011.05.019

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    journal_title:Revue des maladies respiratoires

    pub_type: 杂志文章

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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:

    authors: Weitzenblum E,Arnaud F,Bignon J,Boutin C,Brune J,Castaing Y,Courty G,Derenne J,Duroux P,Fréour P

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  • [Epidemiology of obstructive sleep apnoea syndrome].

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  • [Diagnostic and therapeutic strategies in exacerbations of chronic bronchitis in city practice].

    abstract::The consensus conference convened by the French Language Society for Infectious Disease at Lille in 1991 stressed the fact that two germs were most often the cause of exacerbation in chronic bronchitis (Streptococcus pneumoniae and Haemophilus influenzae) and that antibiotic therapy was the "safe solution" and that th...

    journal_title:Revue des maladies respiratoires

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    authors: Taytard A,Vernejoux JM,Villanueva P,Tunon De Lara JM

    更新日期:1995-01-01 00:00:00

  • [Disseminated histoplasmosis in an HIV seropositive patient].

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    journal_title:Revue des maladies respiratoires

    pub_type: 杂志文章,评审

    doi:

    authors: Herry I,Antoine M,Roux P,Girard PM,Mayaud C,Cadranel J

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  • [Experimental study in the cat on the alveolar density and heterogeneity in the obstructed lung. Comparison with the emphysematous lung in the aged].

    abstract::An experimental model of lung obstruction has been achieved in the cat reared in our laboratory. 30 young adults (J) and one adult subject (A) had tracheal stenosis from 8 to 15 weeks and were the object of a study of pulmonary airways and were compared with four young controls and seven older controls. The presence o...

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    authors: Reichart E,Martin JC

    更新日期:1989-01-01 00:00:00

  • [Manual airway clearance techniques in adults and adolescents: What level of evidence?]

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    journal_title:Revue des maladies respiratoires

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    doi:

    authors: Lulin J,Laidet B,Fur JL,Lezoraine C,Quere O,Rivoallan N

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  • [The importance of lung volumes in the investigation of heavy smokers].

    abstract:INTRODUCTION:Lung hyperinflation (LH) has become a major concern in the management of chronic obstructive pulmonary disease (COPD). MAIN AIM:To evaluate the role of lung volumes in the positive diagnosis of COPD and in the assessment of airway obstruction reversibility. POPULATION AND METHODS:Three hundred and sixty-...

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  • [Bronchial provocation tests in 59 asthmatic children. Comparison with skin tests and specific serum allergens].

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    doi:

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    abstract::Diaphragmatic strength, which can be roughly estimated by non invasive techniques such as maximal inspiratory pressure or sniff nasal pressure, is specifically assessed by the measurement of transdiaphragmatic pressure during electric or magnetic phrenic nerve stimulation. However, muscle endurance is probably a more ...

    journal_title:Revue des maladies respiratoires

    pub_type: 杂志文章,评审

    doi:

    authors: Perez T

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  • [Study of forced expiratory flow rates in respiratory paralysis].

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    doi:

    authors: Leroy M,Jaeger-Denavit O,Liot F

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  • [Longitudinal follow-up of contact subjects of cases of tuberculosis in Paris].

    abstract:AIM:To our knowledge, the proportion of active tuberculosis diagnosed after 12-18 months during a screening tuberculosis process in a specialized centre (centre de lutte antituberculeuse [CLAT]) has not been described in France. The majority of other countries do not have any recommendation to screen at this time. MET...

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  • [In vivo kinetics of cotrimoxazole in alveolar macrophages].

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    doi:

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  • [The e-cigarette disrupts other consumptions in Parisian teenagers (2012-2014)].

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    pub_type: 杂志文章,评审

    doi:

    authors: Manenti A,Gibertini G,Buttazzi A,Barbieri A

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