Abstract：
OBJECTIVES:To analyze experimentation with and use of e-cigarette by middle school and high school students in Paris. METHOD:Since 2012, questions about e-cigarette use have been included in the cross-sectional survey on tobacco that is administered annually since 1991 by the Paris sans tabac association. Overall, 2% of the 12-19 years-old attending school in Paris were surveyed. RESULTS:Of the 10,051 teenagers aged 12-19 surveyed in 2012-2014, 21.8% (n=2194) had tried e-cigarettes. Among these experimenters, 58.9% (n=1292) were smokers, 37.4% (n=820) were non-smokers and 3.7% (n=82) were ex-smokers. From 2012 to 2014, the rate of e-cigarette experimenters increased significantly (from 7.9% to 26.3% for 12-15 years and from 12.2% to 47.2% for 16-19 years-old). The rate of regular e-cigarettes users increased in the same proportion. However over this time, there has been a decline from 15.3% to 10.9% in the rate of 12-15 year old smokers (regular or occasional) and from 38.3% to 33.5% of smokers aged 16-19. Other consumption (cannabis, alcohol abuse) also decreased but no causal relationship can be established. CONCLUSION:The annual doubling of e-cigarette experimentation and regular use rates has been associated with a decrease in the consumption of tobacco and other products. These data should provide some reassurance against fears that e-cigarette use among young people will provide a significant gateway to tobacco smoking.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Dautzenberg B,de Souza Moura MA,Rieu N,Dautzenberg MD,Birkui Pdoi
10.1016/j.rmr.2015.05.010subject
Has Abstractpub_date
2016-03-01 00:00:00pages
225-34issue
3eissn
0761-8425issn
1776-2588pii
S0761-8425(15)00230-2journal_volume
33pub_type
杂志文章abstract：:Epidermal growth factor receptor (EGFR) is a cell membrane tyrosine kinase receptor. Activating mutations at exon 19 and 21 of the EGFR gene are associated with the occurrence and development of lung adenocarcinoma. These gain of function mutations predict responsiveness to EGFR tyrosine kinase inhibitors (TKis), erlo...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2011.03.005
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:To update full time educated youth data on smoking prevalence related to gender and to assess perception and behaviour related to smoking, we have led a self-administrated question-study from January to June 2002 in Abidjan with students from 8 to 22 years old. METHODS:Our population was divided in 3 groups...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(04)71410-2
更新日期：2004-09-01 00:00:00
abstract：INTRODUCTION:Pulmonary arterial hypertension (PAH) is related to hypertrophic remodelling of the pulmonary vessels. Proliferation of pulmonary vascular smooth muscle cells (PA-SMCs) plays a key role in these changes. BACKGROUND:The PA-SMCs of patients suffering from idiopathic or secondary PAH are characterized by abn...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-01 00:00:00
abstract：:Since 1975, 340 patients were treated by tracheal sleeve resection for tracheal or subglottic laryngeal iatrogenic stenoses in our unit. Preoperative iterative Nd YAG laser sessions have usually been performed, without success. The length of the sleeve specimen was an average of 3 1/4 cm. Twelve patients died on the p...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：:General reviews about occupational asthma divide the susceptible allergens capable of initiating asthma into two distinct groups: those of high and of low molecular weight. Atopy would be a risk factor for developing occupational asthma to high molecular weight allergens but not to those of low molecular weight. In th...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：INTRODUCTION:In France, long-term follow-up after occupational exposure to asbestos is recommended. This study looked at the psychological consequences in the longer term following a CT-scan, in particular the impact of having received compensation for an occupational disease. METHODS:As part of an asbestos post-expos...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2019.06.009
更新日期：2019-10-01 00:00:00
abstract：:Treatment of patients with small-cell lung cancer (SCLC) remains disappointing despite high initial complete response rate. The dramatic initial chemosensitivity of tumor cells is frustrated by the early emergence of drug resistant clonogenic cells, regardless of front line treatments. Enhancement of dose-intensity (D...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1997-09-01 00:00:00
abstract：:The article has as purpose to propose a systematic approach for the reading of meta-analysis. Using a particular example, a literature search is proposed to identify the two types of meta-analyses: those based on individual data of the patients and those performed in systematic reviews of the literature. The proposed ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
abstract：:The long term outcome for 88 patients with bullous emphysema who had operations was analysed from the clinical, respiratory function and occupational point of view. In order to reduce to the minimum any bias which would be likely to appear as a result of a decrease in the number of patients with time respiratory funct...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1999-11-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2011.05.016
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
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abstract：:Inhaled medications are widely used in patients suffering from bronchial diseases. Beside their pharmacological properties, nebulised solutions have physico-chemical characteristics that can alter bronchial reactivity. Non-isotonic solutions can induce a bronchial hyperresponsiveness and/or a severe bronchonconstricti...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2013.09.019
更新日期：2015-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2013.07.009
更新日期：2014-02-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2013.09.014
更新日期：2013-12-01 00:00:00
abstract：INTRODUCTION:Alpha-1 antitrypsin deficiency is a hereditary disease defined at the biological level by a serum alpha-1 antitrypsin level below 11μM/L. The null variants are characterized by undetectable circulating alpha-1 antitrypsin levels. Suspicion of a null variant requires the use of appropriate diagnostic techni...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2016.10.878
更新日期：2017-09-01 00:00:00
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journal_title：Revue des maladies respiratoires
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doi：
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
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更新日期：2020-06-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2016.05.001
更新日期：2017-03-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2008-10-01 00:00:00
abstract：:Recent multi-centre studies have shown that high doses of Almitrine (100-200 mg per day), lead to a significant improvement in the hypoxaemia of patients presenting with chronic airflow obstruction, but that a high blood level (greater than 500 ng/ml) is often seen after 1 year, sometimes associated with signs of peri...
journal_title：Revue des maladies respiratoires
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：1992-01-01 00:00:00
abstract：:The authors explain the different types of legislation, according to dissimilar systems, which enable the Social Security or private services to take charge of the care required for occupationally acquired asthma. They emphasize that compensation is currently specified in the different countries by official internatio...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:Chest radiograph and computed tomography are the most appropriate imaging tools for detecting asbestos-related pleural and parenchymal disease due to their availability and performances. The cost and irradiation delivery of conventional chest X-rays are limited. Technical parameters and reading should be standardized....
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1999-12-01 00:00:00
abstract：:This article reports an exchange of unbiased arguments between Mr Guy Postiaux speaking in favour of respiratory physiotherapy in acute viral bronchiolitis in the newborn and Prof. Jean-Christoph Dubus arguing against. A review of the literature suggests that traditional methods of physiotherapy should be abandoned be...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2017.08.003
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Optimal duration of first line chemotherapy for non surgical non small cell lung cancer (NSCLC) is still debated. It concerns the length of initial chemotherapy and the use of maintenance treatments. METHODS:Literature review was performed on maintenance and duration of chemotherapy. RESULTS:The use of mai...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2006-11-01 00:00:00
