Abstract：
INTRODUCTION:The evolution of the microbial epidemiology of pleuropulmonary infections complicating community-acquired pneumonia has resulted in a change in empirical or targeted antibiotic therapy in children in the post Prevenar 13 era. The three main pathogens involved in pleural empyema in children are Streptococcus pneumoniae, Staphylococcus aureus and group A Streptococcus. METHODS:A questionnaire according to the DELPHI method was sent to experts in the field (paediatric pulmonologists and infectious disease specialists) in France with the purpose of reaching a consensus on the conservative antibiotic treatment of pleural empyema in children. Two rounds were completed as part of this DELPHI process. RESULTS:Our work has shown that in the absence of clinical signs of severity, the prescription of an intravenous monotherapy is consensual but there is no agreement on the choice of drug to use. A consensus was also reached on treatment adjustment based on the results of blood cultures, the non-systematic use of a combination therapy, the need for continued oral therapy and the lack of impact of pleural drainage on infection control. On the other hand, after the second round of DELPHI, there was no consensus on the duration of intravenous antibiotic therapy and on the treatment of severe pleural empyema, especially when caused by Staphylococci. CONCLUSIONS:The result of this work highlights the needed for new French recommendations based on the evolution of microbial epidemiology in the post PCV13 era.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Leoni MC,Hau I,Biscardi S,Jung C,Delestrain C,Mangiapan G,Nattes E,Madhi F,Epaud Rdoi
10.1016/j.rmr.2020.04.010subject
Has Abstractpub_date
2020-06-01 00:00:00pages
443-450issue
6eissn
0761-8425issn
1776-2588pii
S0761-8425(20)30144-3journal_volume
37pub_type
杂志文章abstract：:We report the results of a retrospective study of a group of 27 patients with a myopathy who were ventilated at home using a nasal mask over a period of 5 years. Twelve patients were ventilated in a preventive fashion before any orthopaedic surgical intervention and 15 out of necessity because of respiratory failure a...
journal_title：Revue des maladies respiratoires
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更新日期：1991-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
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journal_title：Revue des maladies respiratoires
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doi：
更新日期：1999-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
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journal_title：Revue des maladies respiratoires
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journal_title：Revue des maladies respiratoires
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doi：
更新日期：1998-10-01 00:00:00
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journal_title：Revue des maladies respiratoires
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更新日期：2010-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2003-09-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
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journal_title：Revue des maladies respiratoires
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doi：10.1016/j.rmr.2015.02.004
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2010.10.006
更新日期：2010-12-01 00:00:00
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journal_title：Revue des maladies respiratoires
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doi：10.1016/j.rmr.2010.06.022
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2000-11-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2003-12-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
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journal_title：Revue des maladies respiratoires
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更新日期：2006-11-01 00:00:00
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journal_title：Revue des maladies respiratoires
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doi：10.1016/j.rmr.2012.04.010
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journal_title：Revue des maladies respiratoires
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journal_title：Revue des maladies respiratoires
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更新日期：2006-12-01 00:00:00
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journal_title：Revue des maladies respiratoires
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journal_title：Revue des maladies respiratoires
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更新日期：2011-04-01 00:00:00
