Abstract：
:The imaging techniques used to investigate patients with asthma and to assess the effects of asthma treatments include computed tomography (CT), helium magnetic resonance imaging (MRI), single-photon emission computed tomography (SPECT), and positron-emission tomography (PET). Only MRI does not involve radiation exposure. Technical improvements in CT, together with the imaging advantages inherent in the presence of air in the lung, have diminished the radiation exposure required for lung CT. High-resolution low-dose lung CT protocols deliver a dose roughly equal to 1 year of natural radiation exposure and can be used even in paediatric patients. To date, CT is the most extensively studied lung imaging method, the simplest to perform, and the least expensive. In patients with asthma, CT may show several structural changes related to small-airway disease including cylindrical bronchiolectasis, bronchial wall thickening, and air trapping; an indirect marker for bronchiolar obstruction. A robust body of evidence indicates that valid CT markers for small-airway disease can be derived from quantitative lung density measurements and that these markers correlate with clinical severity and lung function test results. In addition, these CT markers are sufficiently sensitive to demonstrate therapeutic effects.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Laurent F,Tunon de Lara Mdoi
10.1016/j.rmr.2011.05.001subject
Has Abstractpub_date
2011-06-01 00:00:00pages
e7-10issue
6eissn
0761-8425issn
1776-2588pii
S0761-8425(11)00207-5journal_volume
28pub_type
杂志文章,评审abstract：:The development of fibreoptic bronchoscopy has enabled significant progress in the understanding of the pathogenesis of asthma. It has brought to the fore the importance of bronchial inflammation even in asymptomatic patients and/or in patients who have only mild disease. The practice of bronchial biopsy in vivo is an...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1998-06-01 00:00:00
abstract：:One out of two smokers who smoke throughout their lifetime will die from a disease related to smoking. Tobacco smoking therefore represents a major global public health issue. Smoking is the leading cause of chronic obstructive pulmonary disease (COPD). Projections for 2020 indicate that by then, COPD will have become...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2014.07.001
更新日期：2014-12-01 00:00:00
abstract：INTRODUCTION:The correct use of medication and the ability to assess the severity of the disease and to react appropriately in the case of exacerbation are essential objectives in the management of asthma patients. This study, conducted in a school of asthma in Seine-Saint-Denis, aims to measure the influence of socio-...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2014.02.008
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:Hypersensitivity pneumonitis (HP) are typically subacute in their presentation and the diagnosis may be difficult. METHOD:We report a case of a hypersensitivity pneumonitis in a 27-years-old woman, caused by exposure to mould in an insalubrious mobile home. The initial presentation was with acute respirat...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2017.12.006
更新日期：2019-06-01 00:00:00
abstract：:Sarcoidosis is a granulomatous disorder of unknown aetiology accompanied by variable immunological changes which concern both the monocyte and lymphocyte cell line. During the course of this disease anomalies of distribution (with accumulation in the disease tissue contrasting with a peripheral lymphopenia) and also o...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：INTRODUCTION:Although guidelines recommend the prescription of written asthma action plans (WAAP), their use remains limited. METHODS:A prospective survey was performed from 2013 to 2014. We interviewed respiratory physicians, paediatric respiratory physicians and allergologists taking care of asthmatic patients and p...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2015.10.001
更新日期：2016-05-01 00:00:00
abstract：:Latent tuberculosis infection is a pathophysiological and clinical entity. The diagnosis is based on immunological tests such as the tuberculin skin test or interferon-gamma release assays. Interpretation of the results depends on the clinical context. Their predictive value for the occurrence of tuberculous disease i...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2011.05.019
更新日期：2012-02-01 00:00:00
abstract：:Treatment of patients with small-cell lung cancer (SCLC) remains disappointing despite high initial complete response rate. The dramatic initial chemosensitivity of tumor cells is frustrated by the early emergence of drug resistant clonogenic cells, regardless of front line treatments. Enhancement of dose-intensity (D...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1997-09-01 00:00:00
abstract：INTRODUCTION:Six minutes walking test (6MWT) is regularly used in pulmonology. To minimize the risk of cross-infection, some patients must wear surgical mask at rest and sometimes during exercise. AIM OF THE STUDY:To evaluate the effect of wearing a surgical mask during 6MWT in healthy subjects. MATERIAL AND METHOD:I...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.rmr.2017.01.010
更新日期：2018-03-01 00:00:00
abstract：:We report the results of a retrospective study of a group of 27 patients with a myopathy who were ventilated at home using a nasal mask over a period of 5 years. Twelve patients were ventilated in a preventive fashion before any orthopaedic surgical intervention and 15 out of necessity because of respiratory failure a...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：INTRODUCTION:Positron emission tomography (PET) with 18F-FDG has become an important tool for the characterization of solitary pulmonary nodules (SPN). BACKGROUND:The results of the main meta-analyses show that the sensitivity and specificity of 18F-FDG PET for determining malignancy of SPN are close to 95% and 80% re...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/s0761-8425(09)73531-4
更新日期：2009-12-01 00:00:00
abstract：:The authors describe a case of drug-induced cytolytic hepatitis probably secondary to hypersensitivity to allopurinol which was prescribed incorrectly for secondary hyperuricaemia during treatment with pyrazinamide. The diagnosis was reviewed in view of the late occurrence of hepatitis in relation to the onset of the ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:This review highlights the numerous molecular biology findings in the field of lung cancer with potential therapeutic impact in both the near and distant future. Abundant pre-clinical and clinical data indicate that BRCA1 mRNA expression is a differential modulator of chemotherapy sensitivity. Low levels predict cispl...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2006-11-01 00:00:00
abstract：:Bradykinin and related kinins formed in tissues and fluids during inflammation, exert many physiological effects mediated by two receptor subtypes: B1 and B2. The involvement of kinins in bronchial asthma has been speculated in numerous clinicals reports. The effects of bradykinin on airways have been studied in vivo ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：:The authors report the case of chronic destructive polychondritis (PCA) with extensive and predominant laryngo-tracheal involvement. The respiratory localisation of PCA is apparent in around 50% of cases. In a quarter of patients presenting with this type of localisation, the outcome is fatal. Tracheal disorders as th...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：INTRODUCTION:Exhaled carbon monoxide (ECO) concentration provides an easy, fast and non invasive means of assessing smoking status. However, some difficulties have to be considered when interpreting ECO levels. BACKGROUND:CO is a non-specific biomarker of tobacco exposure. Its half-life is short (2-6 hours). CO reflec...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2009.09.004
更新日期：2010-04-01 00:00:00
abstract：:Hypersensitivity pneumonitis (HP) is an interstitial lung disease caused by an immune response to a variety of antigens to which patients have been previously sensitised. It can occur at any age. In children, it is a rare disease, probably under-diagnosed, with an estimated prevalence of 4 per million. The paediatric ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2018.06.010
更新日期：2019-04-01 00:00:00
abstract：:The objective of this work was to describe the profile of routinely managed tuberculosis patients whose sputum smear did not become negative after the initial phase of anti-tuberculous treatment and to analyze the factors associated with this. With this aim a cross-sectional, retrospective, descriptive and analytical ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2017.06.004
更新日期：2018-05-01 00:00:00
abstract：INTRODUCTION:The initiation of oxygen therapy for acute or chronic respiratory failure is a common medical intervention, both for hospital in-patients and in out-of-hospital emergency settings. Oxygen therapy is also frequently initiated by paramedics or nurses, without any initial medical prescription, in acutely ill ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:Utilization of Diagnosis Related Groups (DRGs') for hospital payments in France. OBJECTIVES:To search the variations and the explicative factors of length of stay in a pneumologic unit, to analyse the relevance of the indicators by using the DRG's and the supplementary variables in a medical and economical ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：INTRODUCTION:Mycobacterium avium complex can be responsible for a number of different radio-clinical presentations, ranging from invasive infections to hypersensitivity pneumonitis due to repeated inhalation of antigens. The diagnosis of hypersensitivity pneumonitis is clinical, radiological, biological and microbiolog...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2017.10.670
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:To estimate the prevalence of treated chronic obstructive pulmonary disease (COPD) and its associated costs by stage of severity. METHODS:The study was conducted on the 2011 data of the french general beneficiary sample database (EGB). EGB is a 1/97th sample of the whole population of the beneficiaries of t...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2014.10.731
更新日期：2015-09-01 00:00:00
abstract：INTRODUCTION:Patients suffering from sarcoidosis sometimes report dyspnoea of effort. The restrictive or obstructive ventilatory problems contribute to this disability, but the systemic manifestations of sarcoidosis should be considered as other possible causes of the dyspnoea. CASE REPORT:We report a case of systemic...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：INTRODUCTION:Chest physiotherapy is regularly prescribed for children, particularly in cystic fibrosis. Gastro-oesophageal reflux is common in this disease and is associated with certain chest physiotherapy manoeuvres. AIM OF THE STUDY:To evaluate the influence of two chest physiotherapy techniques on gastro-oesophage...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2015.02.004
更新日期：2015-05-01 00:00:00
abstract：:Bronchial provocation tests are useful for the detection of subclinical bronchial hyper-reactivity. Their standardisation is vital, in particular the method of administration of the bronchoconstrictor agent. Our study compares two systems of histamine delivery: an aerosol propellant with freons and a jet nebuliser lin...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:60 patients were studied with severe chronic respiratory failure (IRC) and a permanent tracheostomy treated with domiciliary ventilation (VADT). The study commenced from the time of the tracheostomy and included length of survival (by the actuarial method) quality of life, subjectively and objectively (progress of blo...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：METHODS:A questionnaire was sent to 50 000 general practicioners (GP) and specialists. RESULTS:4,898 physicians (9.4%) responded, including 59.1% GP, 16.9% pneumologists, 13% pediatricians and about 10% other specialists, ENT, allergologists, and intensivists. The main reason for pneumologists to prescribe nebulizatio...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(08)70465-0
更新日期：2008-01-01 00:00:00
abstract：:The authors review the literature about respiratory burns and their initial and late functional repercussions. Upper airway oedema induces initial upper airway obstructive impairment. Pulmonary parenchymal failure is characterised by the functional consequences observed with adult respiratory distress syndrome. Surviv...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Functional studies of bronchial smooth muscle contractility, particularly in humans, are now well standardized regarding to tissues collection, tension setting and results expression. This type of model is usually considered as simple for analysis of pharmacological interactions between ligands and receptors. In fact,...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2000-06-01 00:00:00
abstract：BACKGROUND:Patients with chronic hypercapnic respiratory failure due to chronic obstructive pulmonary disease (COPD) are very likely to develop acute exacerbations. Non-invasive ventilation is often used to treat acute respiratory failure but little information is available about the benefits of domiciliary non-invasiv...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.rmr.2012.09.006
更新日期：2012-11-01 00:00:00
