Abstract:
:Functional studies of bronchial smooth muscle contractility, particularly in humans, are now well standardized regarding to tissues collection, tension setting and results expression. This type of model is usually considered as simple for analysis of pharmacological interactions between ligands and receptors. In fact, the multiplicity of cell types implicated in the bronchial response makes of isolated bronchi preparation a complex model. Examples are given with studies on endothelin or tachykinins. Inflammation and bronchial hyperresponsiveness models were proposed. Models of passive sensitization or pretreatment with cytokines are described. Functional studies of contractility are included in larger investigations including the analysis of the associated biochemical and electrical phenomenon.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Advenier C,Naline E,Molimard M,Marthan Rsubject
Has Abstractpub_date
2000-06-01 00:00:00pages
534-8issue
2 Pt 2eissn
0761-8425issn
1776-2588journal_volume
17pub_type
杂志文章,评审abstract:INTRODUCTION:C2 spinal cord hemisection interrupts descending bulbospinal respiratory axons coursing through the cervical spinal cord. One consequence of this type of spinal cord injury is the partial deafferentation of the ipsilateral phrenic nucleus, which renders the hemidiaphragm paralysed. The biochemical properti...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::We report a case of lipoid pneumonia complicated by supra-infection with Mycobacterium fortuitum. The diagnosis of a lipoid pneumonia was suggested by the CT Scanner which showed a negative density in the pneumonic tissue. The supra-infection by the mycobacterium dit not change the radiological opacities which stayed ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:In order to achieve a better definition of the indications for surgical excision of pulmonary metastases in colorectal cancer (CCR), a retrospective study of the eight year survival of patients who had been operated on was carried out with reference to the principal prognostic factors. METHODS AND RESULTS:Be...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract:INTRODUCTION:Cardiopulmonary exercise testing (CPET) is used to evaluate the severity of interstitial lung diseases, particularly when lung function is normal. The aim of this study was to analyse exercise capacity of patients with alveolar proteinosis. METHODS:We studied 7 patients undergoing alveolar proteinosis (ag...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1019/200530119
更新日期:2005-12-01 00:00:00
abstract::Several filters specific for respiratory function tests have been on the market for several years. Recommended by the manufacturers to avoid contaminating the equipment and thus improve patient safety, these filters require a considerable financial investment. We studied the passage of diluted blood into artificial sa...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract::Asbestos-related benign pleural lesions can involve the parietal pleura (pleural plaques), and/or visceral pleura as focal or diffuse (diffuse pleural thickening) fibrosis. Benign asbestos pleurisy and rounded atelectasis are linked with visceral pachypleuritis, the former as a cause, the latter as a consequence. The ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1999-12-01 00:00:00
abstract::In order to achieve mediastinal lymph node staging in bronchial cancer, axial mediastinoscopy (combined with left anterior mediastinoscopy for cancers of the left upper lobe) is by far the most efficient and the most reliable technique. Since mediastinoscopy has been part of the investigations that can be made before ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::The authors report an "analytic epidemiological" study, showing the risk of relapse in tuberculous patients in the Bas-Rhin in 1967 to 1977. This was possible thanks to statutory notification of tuberculous cases, with an index updated by annual returns. The study relates to French subjects notified as new cases of al...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The diaphragm is the muscle most implicated in breathing. Its morphological exploration usually depends on pulmonary radiography, fluoroscopy, CT-scanning and MRI. Its function is evaluated by the classical respiratory functional tests, the measurement of maximum inspiratory and expiratory pressures, the transdiaphrag...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2017.02.005
更新日期:2017-06-01 00:00:00
abstract:INTRODUCTION:Many pregnant women are asthmatics and maternal asthma is a source of questions and complications concerning both the progress of the pregnancy itself and the impact on the foetus. In this situation good asthma control is essential as the disease can deteriorate with acute exacerbations, possibly precipita...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/s0761-8425(09)74042-2
更新日期:2009-04-01 00:00:00
abstract::This review highlights the numerous molecular biology findings in the field of lung cancer with potential therapeutic impact in both the near and distant future. Abundant pre-clinical and clinical data indicate that BRCA1 mRNA expression is a differential modulator of chemotherapy sensitivity. Low levels predict cispl...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:2006-11-01 00:00:00
abstract::Spiral scanning (BSV) is a newly acquired scanning technique for all or part of the thoracic volume in a single breath-hold. It offers many advantages when compared to conventional CT scanning. The study of the lungs with a single breath-hold avoids the inconvenience of an anatomical discontinuity while acquiring the ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:Knowledge of prognostic factors is important for therapeutic decision making but above all, at a population level, for the interpretation of data in the literature and as a guide to clinical research. To be useful in practice they must be both independent and reproducible. Despite an impressive number of p...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:2005-12-01 00:00:00
abstract:INTRODUCTION:In western countries, community-acquired pneumonias due to Klebsiella pneumoniae (Kp) are rare and associated with a poor prognosis and a high mortality. The severity is in part linked to the virulence of Kp. Immuno-depression, sepsis and visceral abscesses are frequently found, constituting other classica...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(09)72429-5
更新日期:2009-09-01 00:00:00
abstract:INTRODUCTION:This article is devoted to the critical appraisal of cost-effectiveness analysis. METHODS:The example chosen concerns the choice of first line chemotherapy for a patient with stage IV non small cell bronchial carcinoma; a common problem in thoracic oncology. It compares three chemotherapy regimes: vinorel...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:While wheezing disorders are common in preschool children, their management is not well defined. The aim of this study was to assess the use of medical health care resources due to wheezing disorders in infants aged 18 months followed up in the Pollution and Asthma Risk: an Infant Study (PARIS) birth cohort....
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2011.05.016
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Blunt chest trauma is a frequent injury and it can be difficult to evaluate its seriousness. The risk of acute decompensation because of an occult thoracic lesion is a significant and justified cause for concern. STATE OF ART:As is common in the case of trauma to the torso, few studies are available to gu...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2010.09.028
更新日期:2011-02-01 00:00:00
abstract::The authors report a case of a plasma cell granuloma in a young woman of 19 with a past history of congenital rubella, presenting with repeated small haemoptyses related to a pedunculated endo-bronchial tumour. The diagnosis was only made per-operatively, permitting an effective excision. ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:INTRODUCTION:Mechanical ventilation is associated with ventilator-induced diaphragmatic dysfunction (VIDD) in animal models and also in humans. BACKGROUND:The main pathophysiological pathways implicated in VIDD seems to be related to muscle inactivity but may also be the consequence of high tidal volumes. Systemic ins...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2014.08.013
更新日期:2015-04-01 00:00:00
abstract::The house-dust mites are responsible for the majority of allergic asthma. It is currently possible to measure the exposure to their allergens, and this allows for a better guide as to the indications for eviction measures; there is also a more objective appreciation of the efficacy of these measures. A decrease in the...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:INTRODUCTION:Bronchoalveolar lavage (BAL) was previously considered as the standard diagnostic procedure to investigate pneumonia occurring in immunocompromised patients, and it is probably still widely used. However, the development of new microbiological diagnostic tools, applicable to samples obtained non-invasively...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2020.06.016
更新日期:2020-10-01 00:00:00
abstract::Sarcoidosis is a granulomatous disorder of unknown aetiology accompanied by variable immunological changes which concern both the monocyte and lymphocyte cell line. During the course of this disease anomalies of distribution (with accumulation in the disease tissue contrasting with a peripheral lymphopenia) and also o...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::Our study aimed to assess the impact of acute respiratory failure (ARF) on survival of patients with chronic obstructive pulmonary disease (COPD) receiving long-term oxygen therapy (LTOT) plus nasal intermittent positive pressure ventilation (NIPPV). Survival was analysed retrospectively in 24 patients with severe COP...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract::Computed tomography is important for the diagnosis and follow-up of chronic diffuse interstitial lung diseases. Image quality has improved from each generation of scanner to the next and this continues to allow a better characterization of extent of pathology, or even the nature of the pathological process (potentiall...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2011.04.016
更新日期:2011-12-01 00:00:00
abstract::The matrix metalloproteinases (MMP) are a multigenic family involving 14 enzymes which can cleave most, if not all, the components of the extracellular matrix (interstitium and basement membranes). The present work reports on the main structural characteristics, the substrate preference and the site synthesis of these...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract::Surgery is the ultimate curative treatment for resectable non-small cell lung cancer (NSCLC). However, the prognosis for operated patients remains disappointing. Multiple randomized studies have shown that administering perioperative chemotherapy improves the prognosis and increases the cure rate by around 3-5%. The p...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2020.12.002
更新日期:2021-01-01 00:00:00
abstract::Congenital bronchial atresia is a rare congenital obliteration of a segmental or lobar bronchus resulting in distension of the corresponding parenchyma. It is seldom diagnosed in the adult. It may lead to infectious complications and, in the long term, to damage to the adjacent lung parenchyma. A surgical resection is...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2010.12.005
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:To describe the residual broncho-pulmonary lesions and evaluate the role of CT scanning at the end of treatment of pulmonary tuberculosis. MATERIALS AND METHODS:Analysis of the initial and end of treatment CT scans of 56 patients with pulmonary tuberculosis according to a reading grid including parenchymato...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2018.08.005
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Pulmonary arterial hypertension is a pulmonary vascular disease with a poor prognosis. Continuous intravenous treatment with prostacyclin analogues requires the placement of a tunnelled catheter. The occurrence of catheter-related infections in this context is unusual due to the alkaline pH of the prostacy...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2017.03.037
更新日期:2018-03-01 00:00:00
abstract::Pleurisies due to the syndrome of ovarian hyperstimulation typically accompany ascites and in their most severe form are associated with haemoconcentration, hypovolaemia and thromboembolic phenomena. It is not unusual in this context for pleural effusions to be isolated. They may occur during treatment for sterility b...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00