Stress-mediated hormetic modulation of aging, wound healing, and angiogenesis in human cells.

abstract：:Both hereditary and environmental factors influence the risk of cancer. Four risk categories, or oncodemes, can exist for a particular kind of cancer, depending upon the presence of neither, one, or both factors: (1) spontaneous, or background; (2) hereditary; (3) environmental; (4) interactive. In the second, mutatio...

journal_title：Annals of the New York Academy of Sciences

authors： Knudson AG

更新日期：1997-12-29 00:00:00

abstract：:Sponsored by the New York Academy of Sciences and with support from the National Institute of Mental Health, the Life Technologies Foundation, and the Josiah Macy Jr. Foundation, "Advancing Drug Discovery for Schizophrenia" was held March 9-11 at the New York Academy of Sciences in New York City. The meeting, comprisi...

journal_title：Annals of the New York Academy of Sciences

authors： Marder SR,Roth B,Sullivan PF,Scolnick EM,Nestler EJ,Geyer MA,Welnberger DR,Karayiorgou M,Guidotti A,Gingrich J,Akbarian S,Buchanan RW,Lieberman JA,Conn PJ,Haggarty SJ,Law AJ,Campbell B,Krystal JH,Moghaddam B,Sawa A

更新日期：2011-10-01 00:00:00

abstract：:Considerable clinical and experimental evidence indicates that loss of vestibular function results in cognitive deficits, especially deficits in spatial memory. These studies demonstrate the importance of balance for the most fundamental of cognitive processes and suggest that information about head acceleration and o...

journal_title：Annals of the New York Academy of Sciences

authors： Smith PF,Brandt T,Strupp M,Darlington CL,Zheng Y

更新日期：2009-05-01 00:00:00

abstract：:An apparently macromolecular factor is isolated from aqueous skin extracts which inhibits DNA synthesis in vivo and in vitro with high efficacy (ID50 in vivo 0.2 pmol/g, in vitro 0.2 pM) and in a highly specific manner showing a point of attack in the late G1-phase of the cell cycle (epidermal G1-chalone). Preliminary...

journal_title：Annals of the New York Academy of Sciences

authors： Richter KH,Clauss M,Höfle W,Schnapke R,Marks F

更新日期：1988-01-01 00:00:00

abstract：:Though several studies show that genetic factors influence individual differences in musical engagement, aptitude, and achievement, no study to date has investigated whether specialization among musically active individuals in terms of choice of instrument and genre is heritable. Using a large twin cohort, we explored...

journal_title：Annals of the New York Academy of Sciences

authors： Mosing MA,Ullén F

更新日期：2018-05-09 00:00:00

abstract：:In this experiment, we investigated the influence of the photoperiod upon androgen receptor (AR) distribution and steroid concentrations in ovaries of 21-day-old bank vole females. Sections (6 mum) were assayed immunohistochemically. ARs were localized in the nuclei of granulosa cells. The strongest immunoreaction was...

journal_title：Annals of the New York Academy of Sciences

authors： Galas J,Slomczynska M,Kwasnik A

更新日期：2005-04-01 00:00:00

abstract：:Classical swine fever (CSF) is a viral transboundary animal disease that is highly contagious among domestic and wild pigs, such as boars and peccaries. Today, far from being what was classically described historically, the disease is characterized as having a varied clinical picture, and its diagnosis depends on reso...

journal_title：Annals of the New York Academy of Sciences

authors： Vargas Terán M,Calcagno Ferrat N,Lubroth J

更新日期：2004-10-01 00:00:00

abstract：:Our earlier studies of translation have led us to a specific numeric coding of nucleotides (A = 0, C = 1, G = 2, and U = 3)--that is, a quaternary numeric system; to ordering of digrams and codons (read right to left: .yx and Z.yx) as ordinal numbers from 000 to 111; and to seek hypothetic transformation of mRNA to 20...

journal_title：Annals of the New York Academy of Sciences

authors： Damjanović ZM,Rakocević MM

更新日期：2005-06-01 00:00:00

abstract：:The electron microscopical studies presented here show that characteristic morphological alterations in mitochondria are a very early hallmark of the hepatocellular apoptotic program. Before chromatin condensation occurs, the outer mitochondrial membrane is focally disrupted and the inner membrane protrudes through th...

journal_title：Annals of the New York Academy of Sciences

authors： Angermüller S,Schümann J,Fahimi HD,Tiegs G

更新日期：1999-01-01 00:00:00

abstract：:CD40 ligand (CD40L) is expressed by activated T cells and interacts with the CD40 molecule present on B cells and endothelial cells, promoting immunoglobulin switching in the former and cytokine upregulation in the latter. CD40L exists in both a soluble (sCD40L) and a membrane-bound form. Because primary biliary cirrh...

journal_title：Annals of the New York Academy of Sciences

authors： Oertelt S,Invernizzi P,Selmi C,Podda M,Gershwin ME

更新日期：2005-06-01 00:00:00

abstract：:The molecular biological approach has provided important information toward understanding the complexities of the F0F1 ATPase. This article focuses on our recent results on the ATPase catalytic site contained in the beta subunit and the role of the gamma subunit in regulation of proton transport. We used a combination...

journal_title：Annals of the New York Academy of Sciences

authors： Nakamoto RK,Shin K,Iwamoto A,Omote H,Maeda M,Futai M

更新日期：1992-11-30 00:00:00

abstract：:Acanthamoeba castellanii (A. castellanii) is a common soil- or water-borne protozoon that feeds on bacteria by phagocytosis. A. castellanii can grow between 4 and 32 degrees C and has to adapt quickly to chilling in order to survive. We have identified a Delta12-fatty acid desaturase as key to low temperature adaptati...

journal_title：Annals of the New York Academy of Sciences

authors： Harwood JL

更新日期：2007-10-01 00:00:00

abstract：:Natural systems cannot be closed to the environment. At the same time there is a necessity for closure in order to build the system. It is this quint-essential tension between openness and closure that drives systems to unfold into further stages or levels of growth and development. In other words, the emergence of or...

journal_title：Annals of the New York Academy of Sciences

authors： Alvarez De Lorenzana JM

更新日期：2000-01-01 00:00:00

abstract：:In amphibians, alpha-MSH secreted by the pars intermedia of the pituitary plays a pivotal role in the process of skin color adaptation. Reciprocally, the skin of amphibians contains a number of regulatory peptides, some of which have been found to regulate the activity of pituitary melanotrope cells. In particular, th...

journal_title：Annals of the New York Academy of Sciences

authors： Vaudry H,Chartrel N,Desrues L,Galas L,Kikuyama S,Mor A,Nicolas P,Tonon MC

更新日期：1999-10-20 00:00:00

abstract：:To test the utility of the UCLA posttraumatic stress disorder (PTSD) Index for DSM-IV (U-PTSD-I)(c) for predicting PTSD diagnosis in children with and without medical illnesses. The U-PTSD-I and a standard psychiatric interview were administered to medically ill children (n = 76) and children who experienced other tra...

journal_title：Annals of the New York Academy of Sciences

authors： Shemesh E,Annunziato RA,Newcorn JH,Rockmore L,Bierer LM,Cohen JA,Schmeidler J,Yehuda R

更新日期：2006-07-01 00:00:00

abstract：:In rats, arginine vasopressin augments bradycardia associated with baroreflex activation. We investigated whether modulation of peripheral cardiac parasympathetic nerve function by AVP may play a role in this effect. To accomplish this we utilized an in vivo model with which we previously demonstrated both adrenergic ...

journal_title：Annals of the New York Academy of Sciences

authors： Pardini BJ,Lund DD,Schmid PG

更新日期：1993-07-22 00:00:00

abstract：:The sensory and hedonic evaluation of most food-related flavors is mainly dependent on olfactory perception. The sense of smell is able to recognize and discriminate myriads of airborne molecules with great accuracy and sensitivity. The primary processes of odor perception are mediated by the chemosensory olfactory ne...

journal_title：Annals of the New York Academy of Sciences

authors： Breer H

更新日期：2008-04-01 00:00:00

abstract：:A high index of suspicion is essential in arriving at the correct diagnosis of Lambert-Eaton myasthenic syndrome (LEMS). LEMS should be considered in the differential in any patient who has proximal weakness, reduced or absent muscle stretch reflexes, and dry mouth. Weakness predominates in hip and shoulder muscles, b...

journal_title：Annals of the New York Academy of Sciences

authors： Sanders DB

更新日期：2003-09-01 00:00:00

abstract：:TT virus (TTV) is a recently described circular DNA virus of about 3.8 kb, which is related to the circoviridae viruses. It is commonly detected in healthy subjects and no association with any specific disease has been established. TTV was initially thought to be hepatotropic, but subsequent reports have shown that it...

journal_title：Annals of the New York Academy of Sciences

authors： Zhong S,Yeo W,Tang MW,Lin XR,Mo F,Ho WM,Hui P,Johnson PJ

更新日期：2001-09-01 00:00:00

abstract：:Membrane phospholipid metabolism is abnormal in Alzheimer's disease (AD) brain. Phosphatidylcholine and phosphatidylethanolamine levels are decreased as are choline and ethanolamine, while glycerophosphocholine (GPC) and glycerophosphoethanolamine are increased. To develop a rat model for these changes, we examined th...

journal_title：Annals of the New York Academy of Sciences

authors： Holmes TC,Nitsch RM,Erfurth A,Wurtman RJ

更新日期：1993-09-24 00:00:00

abstract：:Gene expression regulation, in particular at the level of transcription, has been demonstrated to play a key role in the development of human diseases, including cancer, and in bacteria it is crucial for proliferation as well as for pathogenicity. Transcriptional regulation is based on complex networks of interactions...

journal_title：Annals of the New York Academy of Sciences

authors： Zorrilla S,Lillo MP,Chaix D,Margeat E,Royer CA,Declerck N

更新日期：2008-01-01 00:00:00

abstract：:Atherosclerotic coronary heart disease and other forms of cardiovascular disease (CVD) are the major cause of mortality in type II diabetes (T2DM) as well as a major contributor to morbidity and lifetime costs. The purpose of this article is the identification of the biochemical parameters in plasma, which may serve a...

journal_title：Annals of the New York Academy of Sciences

authors： Kalofoutis C,Piperi C,Zisaki A,Singh J,Harris F,Phoenix D,Alaveras A,Kalofoutis A

更新日期：2006-11-01 00:00:00

abstract：:In summary, immediate hypersensitivity reactions to luminal antigens occur in the intestine and result in pathophysiology including increased permeability and ion secretion. The mechanism involves activation of mast cells with neural amplification (FIG. 5). Released mediators/neurotransmitters may act independently or...

journal_title：Annals of the New York Academy of Sciences

authors： Perdue MH,Kosecka U,Crowe S

更新日期：1992-01-01 00:00:00

abstract：:Cold-restraint stress reduces gastric blood flow and produces acute gastric ulcers. We studied the role of Angiotensin II (Ang II) on gastric blood flow and gastric ulceration during stress. Spontaneously hypertensive rats, a stress-sensitive strain, were pretreated for 14 days with the AT(1) receptor antagonist cande...

journal_title：Annals of the New York Academy of Sciences

authors： Bregonzio C,Armando I,Ando H,Jezova M,Baiardi G,Saavedra JM

更新日期：2004-06-01 00:00:00

abstract：:Diverse mutations in the gene encoding the copper transporter ATP7A lead to X-linked recessive Menkes disease or occipital horn syndrome. Recently, two unique ATP7A missense mutations, T994I and P1386S, were shown to cause isolated adult-onset distal motor neuropathy. These mutations induce subtle defects in ATP7A int...

journal_title：Annals of the New York Academy of Sciences

authors： Yi L,Kaler S

更新日期：2014-05-01 00:00:00

abstract：:Despite new technological advances in the rehabilitation of audition in profoundly deaf children, auditory training remains a fundamental part of their education. Consequently, it is necessary to learn what kind of stimuli, what kind of auditory tasks, and what kind of learning procedures generate faster and more long...

journal_title：Annals of the New York Academy of Sciences

authors： Rochette F,Bigand E

更新日期：2009-07-01 00:00:00

abstract：:Obesity has various deleterious effects on health largely associated with metabolic abnormalities including abnormal glucose and lipid homeostasis that are associated with vascular injury and known cardiac, renal, and cerebrovascular complications. Advanced age is also associated with increased adiposity, decreased le...

journal_title：Annals of the New York Academy of Sciences

authors： Lee EB

更新日期：2011-12-01 00:00:00

abstract：:Research on nonhuman primates has produced compelling evidence for reconciliation and consolation, that is, postconflict contacts that serve to respectively repair social relationships and reassure distressed individuals, such as victims of attack. This has led to a view of conflict and conflict resolution as an integ...

journal_title：Annals of the New York Academy of Sciences

authors： de Wall FB,Aureli F

更新日期：1997-01-15 00:00:00

abstract：:A fraction with lymphokine properties was isolated from supernatant medium of the continuous cultured human lymphoblast cell line, 1788. Culture medium containing 2% human serum was used for cell growth in order to minimize antigenicity of supernatant fractions isolated from the medium. The culture medium was passed t...

journal_title：Annals of the New York Academy of Sciences

authors： Papermaster BW,Holtermann OA,McDaniel MC,Klein E,Djerassi I,Rosner D,Dao T,Costanzi JJ

更新日期：1976-01-01 00:00:00

abstract：:The fatty acid (FA) compositions of liver and skeletal muscle structural lipids, overall phospholipids and phosphatidylcholine, and triglycerides (TG) were determined in the hereditary hypertriglyceridemic (HTG) rat, a nonobese animal model of the insulin resistance syndrome. Four groups of HTG rats and four groups of...

journal_title：Annals of the New York Academy of Sciences

authors： Bohov P,Seböková E,Gasperíková D,Langer P,Klimes I

更新日期：1997-09-20 00:00:00