Quantification of interstitial fibrosis by image analysis on routine renal biopsy in patients receiving cyclosporine.

abstract：BACKGROUND:Ventricular assist devices (VADs) are increasingly being used in pediatric patients to provide long-term cardiac support. One potential complication of VAD therapy is the development of antibodies directed against human leukocyte antigens (HLA). This phenomenon has not been well described with the Berlin Hea...

journal_title：Transplantation

authors： O'Connor MJ,Harville TO,Rhodes-Clark B,Pye SE,Knecht KR,Imamura M,Frazier EA,Morrow WR

更新日期：2013-06-27 00:00:00

abstract：:In vivo cell-mediated effector mechanisms of allograft destruction were investigated in a canine single-lung transplantation model. This large animal model permits direct longitudinal studies of immune effector cells from the grafts of individual recipients by bronchoalveolar lavage (BAL). Evidence was obtained that t...

journal_title：Transplantation

authors： Norin AJ,Kamholz SL

更新日期：1989-11-01 00:00:00

abstract：:Mixed lymphocyte culture--lymphocyte-mediated cytotoxicity (MLC-LMC) reactions by recipient spleen cells were strongly and specifically increased shortly after primarily vascularized heart grafts were placed in mice. Subsequently, in strain combinations in which eventual long-term graft survival occurred, the MLC-LMC ...

journal_title：Transplantation

authors： Burdick JF,Clow LW

更新日期：1987-04-01 00:00:00

abstract：:Patients who require cystectomy are usually treated with an ileal conduit or intestinal neobladder for urinary control. In some of them, however, the bowel segment cannot be used because of previous abdominal surgery or radiation treatment. Bladder transplantation from cadavers may be beneficial to these patients, if ...

journal_title：Transplantation

authors： Takeuchi K,Takechi S,Ohoka H,Yokoyama M,Iwata H,Takeuchi M,Matsuda S

更新日期：1997-04-15 00:00:00

abstract：:Biliary tract problems remain an important cause of complication following orthotopic hepatic transplantation. We describe 12 liver transplantation patients who developed bile peritonitis secondary to a biliary leak after T tube removal. Each of these patients underwent an urgent ERCP that exhibited leakage outside th...

journal_title：Transplantation

authors： Ostroff JW,Roberts JP,Gordon RL,Ring EJ,Ascher NL

更新日期：1990-05-01 00:00:00

abstract：:Three strains of miniature swine, each homozygous for a different allele of the major histocompatibility locus (MHC), have been developed by a selective breeding scheme based on tissue typing of the offspring of each generation. Prior to breeding, the original parents were reciprocally immunized by skin grafts and lym...

journal_title：Transplantation

authors： Sachs DH,Leight G,Cone J,Schwarz S,Stuart L,Rosenberg S

更新日期：1976-12-01 00:00:00

abstract：:EBVirus-associated B cell lymphoproliferative disorder (BLPD) is a recognized complication of primary immunodeficiency and organ as well as bone marrow transplantation. Although the nature of the immune defects that predispose to the development of BLPD are unknown, it is postulated that aberrant T cell responses are ...

journal_title：Transplantation

authors： Mathur A,Kamat DM,Filipovich AH,Steinbuch M,Shapiro RS

更新日期：1994-04-15 00:00:00

abstract：BACKGROUND:Neutrophilic tubulitis accompanied by intratubular neutrophil clusters in the renal allograft is a surrogate marker for urinary tract infection (UTI). Overlapping histologic findings can occur in antibody-mediated rejection, which is characterized by peritubular capillary (PTC) deposition of C4d. This study ...

journal_title：Transplantation

authors： Gupta G,Shapiro R,Girnita A,Batal I,McCauley J,Basu A,Tan H,Randhawa P

更新日期：2009-04-15 00:00:00

abstract：BACKGROUND:Liver transplant recipients suffer many postoperative complications. Few studies evaluated the effects of fluid management on these complications. We conducted an observational cohort study to evaluate the association between intraoperative fluid balance and postoperative acute kidney injury (AKI) and other ...

journal_title：Transplantation

authors： Carrier FM,Chassé M,Sylvestre MP,Girard M,Legendre-Courville L,Massicotte L,Bilodeau M

更新日期：2020-07-01 00:00:00

abstract：:Monoclonal antibodies to CD3 have been shown to activate T cells in vivo and in vitro but have also been shown to render T cells anergic in vitro. In this study G4.18, a mouse IgG3 mAb, was produced that appeared to recognize CD3 by its binding to all peripheral T cells, including a population not recognized by mAb to...

journal_title：Transplantation

authors： Nicolls MR,Aversa GG,Pearce NW,Spinelli A,Berger MF,Gurley KE,Hall BM

更新日期：1993-03-01 00:00:00

abstract：:Little is known of the host immune mechanisms responsible for initiation and progression of chronic rejection. We describe immunopathologic features associated with progressively deteriorating function of kidney allografts in the F344-to-Lewis rat strain combination, which differ at MHC and non-MHC loci. Initial rejec...

journal_title：Transplantation

authors： Hancock WH,Whitley WD,Tullius SG,Heemann UW,Wasowska B,Baldwin WM 3rd,Tilney NL

更新日期：1993-09-01 00:00:00

abstract：:Organ shortage in liver transplantation has led the transplant community to expand the donor organ pool and reduce waiting list mortality by using so-called marginal donor or extended criteria donor (ECD) livers. The exact impact of these criteria on graft function and recipient survival are still under investigation....

journal_title：Transplantation

authors： Mittler J,Pascher A,Neuhaus P,Pratschke J

更新日期：2008-10-15 00:00:00

abstract：:Enhancement of skin grafts in mice by passively administered alloantiserum was examined in conjunction with the simultaneous use of other immunosuppressive regimens. It could be clearly shown that when a "weak" antilymphocyte serum (ALS) was used, a significant further prolongation of graft survival occurred over that...

journal_title：Transplantation

authors： Koene RA,Gerlag PG,McKenzie IF,Hagemann JF,Wijdeveld PG

更新日期：1975-09-01 00:00:00

abstract：:Experiments have been carried out to investigate whether the continued survival of rat kidney allografts induced by two different methods-namely, immunological enhancement or a limited course of drug treatment with cyclosporine or cyclophosphamide, is maintained by similar mechanisms. (AS X AUG)F1 or AUG strain kidney...

journal_title：Transplantation

authors： Chui YL,Batchelor JR

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Chronic allograft dysfunction (CAD) is a complex phenomenon caused by underlying kidney disease and superimposed environmental and genetic factors. We investigated the association of polymorphisms in the genes for angiotensin-converting enzyme (ACE), angiotensinogen (AGT), angiotensin II receptor type 1 (ATR...

journal_title：Transplantation

authors： Akcay A,Sezer S,Ozdemir FN,Arat Z,Atac FB,Verdi H,Colak T,Haberal M

更新日期：2004-09-27 00:00:00

abstract：:Acute rejection episodes still occur after kidney transplantation in spite of modern immunosuppressive protocols including combined tacrolimus, mycophenolate mofetil, and prednisolone. The authors present seven cases of biopsy-proven acute rejection after kidney transplantation refractory to conventional rejection the...

journal_title：Transplantation

authors： Kumlien G,Genberg H,Shanwell A,Tydén G

更新日期：2005-01-15 00:00:00

abstract：:The properties of rat liver dendritic cells (DC) were analyzed after collagenase digestion of the tissue and enrichment with density gradient centrifugation. The liver macrophages (Kupffer cells) were eliminated by adherence before the gradient centrifugation. The morphology of isolated DC in May-Grunwald-Giemsa (MGG)...

journal_title：Transplantation

authors： Lautenschlager I,Halttunen J,Häyry P

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Adult orthotopic liver transplantation is associated with significant use of allogenic blood products, which places considerable demands on finite resources. This could be reduced by autologous red cell salvage use, and we evaluated its cost effectiveness in this prospective study. METHODS:Intraoperative au...

journal_title：Transplantation

authors： Phillips SD,Maguire D,Deshpande R,Muiesan P,Bowles MJ,Rela M,Heaton ND

更新日期：2006-02-27 00:00:00

abstract：:The effect of cyclosporine and metabolite 17 (M17) as well as other CsA-related compounds (CsG, dihydro-CsC, dihydro-CsD, CsH, B5.49, and H7.94) was tested on T lymphocyte clone proliferation. In these experiments, antigen and interleukin 2 (IL-2) dependent long-term T lymphocyte clones derived from a rejected human k...

journal_title：Transplantation

authors： Chabannes D,Moreau JF,Soulillou JP

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Detection of markers predicting allograft rejection is important for risk assessment before kidney transplantation, as well as to minimize posttransplantation immunosuppression. METHODS:We studied the expression of CD25, HLA-DR, CD134, CD62L, and CD44 by flow cytometry in CD4, CD8, and CD3 cells, from pretr...

journal_title：Transplantation

authors： Hueso M,Mestre M,Benavente Y,Bas J,Grinyó JM,Navarro E

更新日期：2011-09-15 00:00:00

abstract：BACKGROUND:Centrilobular necrosis is not an uncommon finding after isolated liver transplantation. In this study, we sought to describe hepatic centrilobular necrosis in children after combined liver and small bowel transplantation (LSBT), and to assess the predictive factors, possible causes, and prognosis. METHODS:S...

journal_title：Transplantation

authors： Lacaille F,Canioni D,Fournet JC,Revillon Y,Cezard JP,Goulet O

更新日期：2002-01-27 00:00:00

abstract：OBJECTIVE:The purpose of this study was to identify pretransplantation and posttransplantation indicators for the development of diabetes mellitus in the first 2 months after renal transplantation and to examine the influence of a cyclosporine A (CsA)-based versus a tacrolimus-based immunosuppressive regimen on these r...

journal_title：Transplantation

authors： Sato T,Inagaki A,Uchida K,Ueki T,Goto N,Matsuoka S,Katayama A,Haba T,Tominaga Y,Okajima Y,Ohta K,Suga H,Taguchi S,Kakiya S,Itatsu T,Kobayashi T,Nakao A

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:Although the value of duodenal histology as a means to diagnose acute rejection in pancreaticoduodenal allografts has been validated, it is not known how the duodenum responds to antirejection treatment in comparison with the pancreas. METHODS:Diabetic Lewis rats received a pancreaticoduodenal allograft. Cy...

journal_title：Transplantation

authors： Mark W,Hechenleitner P,Dietze O,Klima G,Schneeberger S,Steurer W,Candinas D,Margreiter R,Königsrainer A

更新日期：2002-01-27 00:00:00

abstract：:Histoincompatible-complete radiation chimeras, after resolving acute graft-versus-host disease (GVHD), establish specific tolerance to host and donor alloantigens. This tolerance can be perturbed with immunosuppressive agents and infusions of small numbers of donor-type cells, with infusions of massive numbers of dono...

journal_title：Transplantation

authors： Tutschka PJ,Hess AD,Beschorner WE,Santos GW

更新日期：1981-09-01 00:00:00

abstract：OBJECTIVES:To retrospectively compare the accuracy of pretransplant panel of reactivity antibodies (PRA) and serum level of soluble CD30 (sCD30) in predicting early (<6 months) acute rejection (AR) in living-donor and deceased-donor kidney-transplant (KT) patients. METHODS:Pretransplant sera of 24 KT recipients were r...

journal_title：Transplantation

authors： Cinti P,Pretagostini R,Arpino A,Tamburro ML,Mengasini S,Lattanzi R,De Simone P,Berloco P,Molajoni ER

更新日期：2005-05-15 00:00:00

abstract：:We describe a patient transfused with 200 ml of donor fresh whole blood three times at 2-week intervals. Three weeks after the last transfusion, transplantation and splenectomy were done at the same time. Splenic cells from this DST pretreated patient were fused with murine myeloma cells (X63-Ag8, 653). With DST pretr...

journal_title：Transplantation

authors： Kawamura T,Sakagami K,Haisa M,Morisaki F,Takasu S,Inagaki M,Oiwa T,Orita K

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:To stimulate organ donation, an organ procurement organization (OPO)-wide effort was undertaken to increase donors after cardiac death (DCD) over a 5-year period. This included commonality of protocols, pulsatile perfusion of kidneys, centralization of data and a regional allocation variance designed to mini...

journal_title：Transplantation

authors： Whiting JF,Delmonico F,Morrissey P,Basadonna G,Johnson S,Lewis WD,Rohrer R,O'Connor K,Bradley J,Lovewell TD,Lipkowitz G

更新日期：2006-05-27 00:00:00

abstract：:In a canine model of acute ischemic lung injury, a hypertonic citrate solution (HTC) widely used for renal preservation in the United Kingdom, was compared with modified Euro-Collins' solution (ECS) currently the most widely clinically used pulmonary perfusate. Ten beagle dogs underwent left thoracotomy and exclusion ...

journal_title：Transplantation

authors： Hooper TL,Jones MT,Thomson DS,Cook L,Owen S,Wilkes S,Woodcock A,Webster AH,Hasleton P,McGregor CG

更新日期：1991-05-01 00:00:00

abstract：:The effects of in vivo administration of monoclonal antibodies directed against the two major mature T cell subsets of miniature swine have been examined. Antibody 76-2-11, specific for the porcine CD8 cell-surface antigen, caused elimination of CD8+ T cells from the peripheral lymphocyte pool by 4-6 days following a ...

journal_title：Transplantation

authors： Suzuki T,Sundt TM 3rd,Mixon A,Sachs DH

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Longest bipolar length of the kidney graft is routinely measured for ultrasonographic assessment of graft size (GS), although the value of the graft length remains unclear. METHODS:In a single-center, observational study involving 319 deceased-donor kidney transplant recipients, we assessed variations in ab...

journal_title：Transplantation

authors： Černe S,Arnol M,Kandus A,Buturović-Ponikvar J

更新日期：2016-08-01 00:00:00