Functional connections with foreign muscles made by a target-deprived insect motorneuron.

abstract：:The genetic and developmental bases for trait expression and variation in adults are largely unknown. One system in which genes and cell behaviors underlying adult traits can be elucidated is the larval-to-adult transformation of zebrafish, Danio rerio. Metamorphosis in this and many other teleost fishes resembles amp...

journal_title：Developmental biology

authors： Parichy DM,Turner JM

更新日期：2003-04-15 00:00:00

abstract：:Neural crest cells have broad migratory and differentiative ability that differs according to their axial level of origin. However, their transient nature has limited understanding of their stem cell and self-renewal properties. While an in vitro culture method has made it possible to maintain cranial neural crest cel...

journal_title：Developmental biology

authors： Mohlin S,Kunttas E,Persson CU,Abdel-Haq R,Castillo A,Murko C,Bronner ME,Kerosuo L

更新日期：2019-03-15 00:00:00

abstract：:The Egr family of zinc-finger transcription factors, consisting of Egr1, Egr2, Egr3, and Egr4, are involved in cellular growth and differentiation. Adult Egr3-deficient mice are ataxic and lack muscle spindle proprioceptors that normally develop at the sites of Ia afferent-myotube contacts during embryogenesis. To res...

journal_title：Developmental biology

authors： Tourtellotte WG,Keller-Peck C,Milbrandt J,Kucera J

更新日期：2001-04-15 00:00:00

abstract：:The current picture of embryonic development in nematodes is essentially shaped by Caenorhabditis elegans and its close relatives. As their pattern of embryogenesis is rather similar, it is often considered to be representative for the taxon Nematoda as a whole. Here we give for the first time a comprehensive descript...

journal_title：Developmental biology

authors： Schulze J,Schierenberg E

更新日期：2009-10-01 00:00:00

abstract：:A mutant gene dose-dependent inhibition of cerebellar granule cell neuron survival and neurite growth in dissociated cultures of cerebellum from 7-day-old heterozygous (+/wv) and homozygous (wv/wv) weaver mutant mice (M. Willinger, D. M. Margolis, and R. L. Sidman. (1981), J. Supramol. Struc. 17, 79-86) has previously...

journal_title：Developmental biology

authors： Willinger M,Margolis DM

更新日期：1985-01-01 00:00:00

abstract：:Morphogenesis of the anterior metatarsal skin (scutate scale region), from 9.5 to 12 days of development, results in the formation of orderly patterned scale ridges. It is after the initial formation of the Definitive Scale Ridge that the characteristic outer and inner epidermal surfaces differentiate. The hard, plate...

journal_title：Developmental biology

authors： Shames RB,Jennings AG,Sawyer RH

更新日期：1991-09-01 00:00:00

abstract：:Wnt-4, a member of the Wnt family of secreted signaling molecules, is essential for nephrogenesis, but its expression in the presumptive medulla suggests additional developmental roles in kidney organogenesis. We demonstrate here that Wnt-4 signaling plays also a role in the determination of the fate of smooth muscle ...

journal_title：Developmental biology

authors： Itäranta P,Chi L,Seppänen T,Niku M,Tuukkanen J,Peltoketo H,Vainio S

更新日期：2006-05-15 00:00:00

abstract：:Pulses of ecdysteroids induce dramatic changes in gene expression that direct the early stages of Drosophila metamorphosis. This gene activity is reflected by the appearance of early and late puffs in the salivary gland polytene chromosomes. Curiously, the early puff genes that have been studied to date are induced by...

journal_title：Developmental biology

authors： Baehrecke EH,Thummel CS

更新日期：1995-09-01 00:00:00

abstract：:Accumulating evidence indicates that the endometrial extracellular matrix (ECM) modulates trophoblast adhesion during mouse blastocyst implantation. In previous studies of adhesion-competent mouse blastocysts, we have demonstrated that integrin-mediated fibronectin (FN)-binding activity on the apical surface of tropho...

journal_title：Developmental biology

authors： Wang J,Mayernik L,Armant DR

更新日期：2002-05-15 00:00:00

abstract：:Much of boundary formation during development remains to be understood, despite being a defining feature of many animal taxa. Axial patterning of Hydra, a member of the ancient phylum Cnidaria which diverged prior to the bilaterian radiation, involves a steady-state of production and loss of tissue, and is dependent o...

journal_title：Developmental biology

authors： López-Quintero JA,Torres GG,Neme R,Bosch TCG

更新日期：2020-02-15 00:00:00

abstract：:Stimulation of epithelial cell cycling by the neuropeptide head activator was analyzed in Hydra magnipapillata and compared with the action of head activator on bud formation and tentacle formation during head regeneration. The results obtained indicate that head activator treatment stimulates epithelial cell division...

journal_title：Developmental biology

authors： Hobmayer B,Holstein TW,David CN

更新日期：1997-03-01 00:00:00

abstract：:We have isolated two related Xenopus homologues of the homeotic zinc finger protein Teashirt1 (Tsh1), XTsh1a and XTsh1b. While Drosophila teashirt specifies trunk identity in the fly, the developmental relevance of vertebrate Tsh homologues is unknown. XTsh1a/b are expressed in prospective trunk CNS throughout early n...

journal_title：Developmental biology

authors： Koebernick K,Kashef J,Pieler T,Wedlich D

更新日期：2006-10-01 00:00:00

abstract：:We have studied the differentiation of the oocyte vitelline coat (VC) and jelly coat (JC) of the starfish, Astropecten aurantiacus. The precursor material of both envelopes is secreted by the oocyte while the follicle cells do not appear to participate in the secretory process. The first indication of differentiation ...

journal_title：Developmental biology

authors： Santella L,Monroy A,Rosati F

更新日期：1983-10-01 00:00:00

abstract：:Extracellular modulators of cell-cell signaling control numerous aspects of organismal development. The Twisted gastrulation (Twsg1) gene product is a small, secreted cysteine-rich protein that has the unusual property of being able to either enhance or inhibit signaling by the bone morphogenetic protein (BMP) subfami...

journal_title：Developmental biology

authors： Petryk A,Anderson RM,Jarcho MP,Leaf I,Carlson CS,Klingensmith J,Shawlot W,O'Connor MB

更新日期：2004-03-15 00:00:00

abstract：:In warm-blooded vertebrates it is generally accepted that after early stages of development new neurons are not added to the retina. Contrary to this belief, we show here that hatched chickens have a zone of proliferating cells at the peripheral margin of the retina, similar to that of fish and amphibians. We found th...

journal_title：Developmental biology

authors： Fischer AJ,Reh TA

更新日期：2000-04-15 00:00:00

abstract：:To determine whether low oxygen is a stimulus for endothelial cell differentiation and vascular development in the kidney, we examined the effect of low oxygen on rat metanephric organ culture, a model known to recapitulate nephrogenesis in the absence of vessels. After 6 days in culture in standard (20% O2) or low ox...

journal_title：Developmental biology

authors： Tufro-McReddie A,Norwood VF,Aylor KW,Botkin SJ,Carey RM,Gomez RA

更新日期：1997-03-15 00:00:00

abstract：:Despite 30 years of Hox gene study, we have a remarkably limited knowledge of the downstream target genes that Hox transcription factors regulate to confer regional identity. Here, we have used a microarray approach to identify genes that function downstream of a single vertebrate Hox gene, zebrafish hoxb1a. This gene...

journal_title：Developmental biology

authors： Rohrschneider MR,Elsen GE,Prince VE

更新日期：2007-09-15 00:00:00

abstract：:Heart valve structures derived from mesenchymal cells of the endocardial cushions (ECs) are composed of highly organized cell lineages and extracellular matrix. Sox9 is a transcription factor required for both early and late stages of cartilage formation that is also expressed in the developing valves of the heart. Th...

journal_title：Developmental biology

authors： Lincoln J,Kist R,Scherer G,Yutzey KE

更新日期：2007-05-01 00:00:00

abstract：:XX gonads differentiate into ovaries, a morphologic event evident by embryonic day 13.5 (E13.5) in mice. To identify early markers of oogenesis, sex-specific urogenital ridge cDNA libraries were constructed from E12-13 embryos. After mass excision and isolation of plasmid DNA, approximately 4800 expressed sequence tag...

journal_title：Developmental biology

authors： Takasaki N,McIsaac R,Dean J

更新日期：2000-07-01 00:00:00

abstract：:Congenital diseases caused by abnormal development of the cranial neural crest usually present craniofacial malformations and heart defects while the precise mechanism is not fully understood. Here, we show that the zebrafish eif3ba mutant caused by pseudo-typed retrovirus insertion exhibited a similar phenotype due t...

journal_title：Developmental biology

authors： Xia Z,Tong X,Liang F,Zhang Y,Kuok C,Zhang Y,Liu X,Zhu Z,Lin S,Zhang B

更新日期：2013-09-01 00:00:00

abstract：:NK genes are related pan-metazoan homeobox genes. In the fruitfly, NK genes are clustered and involved in patterning various mesodermal derivatives during embryogenesis. It was therefore suggested that the NK cluster emerged in evolution as an ancestral mesodermal patterning cluster. To test this hypothesis, we cloned...

journal_title：Developmental biology

authors： Saudemont A,Dray N,Hudry B,Le Gouar M,Vervoort M,Balavoine G

更新日期：2008-05-15 00:00:00

abstract：:In previous studies we found that two glycoproteins of 220 and 180 kDa account for 80-90% of the material dissolved from the vitelline coat (VC) of Unio elongatulus egg (Focarelli and Rosati, 1993). The two glycoproteins were purified by electroelution and used to raise the corresponding polyclonal antibodies. Immunof...

journal_title：Developmental biology

authors： Focarelli R,Rosati F

更新日期：1995-10-01 00:00:00

abstract：:To investigate the mechanism by which the hormone 17 alpha,20 beta-dihydroxy-4-pregnen-3-one(17 alpha,20 beta-DP) acts on a receptor on the external surface of rainbow trout oocytes to induce maturation, the interaction between 17 alpha,20 beta-DP receptors and G-proteins was examined. Pertussis toxin (PT) catalyzed t...

journal_title：Developmental biology

authors： Yoshikuni M,Nagahama Y

更新日期：1994-12-01 00:00:00

abstract：:The Hedgehog (Hh) and Notch signal transduction pathways control a variety of developmental processes including cell fate choice, differentiation, proliferation, patterning and boundary formation. Because many components of these pathways are conserved, it was predicted and confirmed that pathway components are largel...

journal_title：Developmental biology

authors： Walton KD,Croce JC,Glenn TD,Wu SY,McClay DR

更新日期：2006-12-01 00:00:00

abstract：:The rise of evolutionary developmental biology was not the progressive isolation and characterization of developmental genes and gene networks. Many obstacles had to be overcome: the idea that all genes were more or less involved in development; the evidence that developmental processes in insects had nothing in commo...

journal_title：Developmental biology

authors： Morange M

更新日期：2011-09-01 00:00:00

abstract：:The vertebrate eye anlage grows out of the brain and folds into bilayered optic cups. The eye is patterned along multiple axes, precisely controlled by genetic programs, to delineate neural retina, pigment epithelium, and optic stalk tissues. Pax genes encode developmental regulators of key morphogenetic events, with ...

journal_title：Developmental biology

authors： Bosze B,Suarez-Navarro J,Soofi A,Lauderdale JD,Dressler GR,Brown NL

更新日期：2021-01-09 00:00:00

abstract：:We have investigated the imprinting status of two insulin genes using an interspecific recombinant congenic mouse strain carrying Ins1 and Ins2 alleles from Mus spretus on a C57BL/6 genetic background. At Days 12.5, 13.5, and 14.5 of gestation, expression of both parental alleles of both Ins1 and Ins2 was detected in ...

journal_title：Developmental biology

authors： Deltour L,Montagutelli X,Guenet JL,Jami J,Páldi A

更新日期：1995-04-01 00:00:00

abstract：:Ligands of the transforming growth factor beta (TGFbeta) superfamily, like Nodal and bone morphogenetic protein (BMP), are pivotal to establish left-right (LR) asymmetry in vertebrates. However, the receptors mediating this process are unknown. Here we identified two new type II receptors for BMPs in zebrafish termed ...

journal_title：Developmental biology

authors： Monteiro R,van Dinther M,Bakkers J,Wilkinson R,Patient R,ten Dijke P,Mummery C

更新日期：2008-03-01 00:00:00

abstract：:The development of germ cells is a highly ordered process that begins during fetal growth and is completed in the adult. Epigenetic modifications that occur in germ cells are important for germ cell function and for post-fertilization embryonic development. We have previously shown that male germ cells in the adult mo...

journal_title：Developmental biology

authors： Oakes CC,La Salle S,Smiraglia DJ,Robaire B,Trasler JM

更新日期：2007-07-15 00:00:00

abstract：:Previous studies suggest that sensory innervation of muscles is patterned by motor innervation. Muscle afferent projections mirror motor projections after various experimental manipulations and muscle afferents fail to project to muscle in the absence of motoneurons. It is not known, however, whether muscle afferents ...

journal_title：Developmental biology

authors： Wang G,Scott SA

更新日期：1997-06-01 00:00:00