当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Effect of Fe2+ -induced lipid peroxidation upon microsomal steroidogenic enzyme activities of porcine adrenal cortex.

Effect of Fe2+ -induced lipid peroxidation upon microsomal steroidogenic enzyme activities of porcine adrenal cortex.

Abstract：

:When porcine adrenocortical microsomes were treated with Fe2+, enhanced production of malondialdehyde was observed as a result of membrane lipid peroxidation. By treatment of the microsomes with Fe2+, the activity of delta 5-3 beta-hydroxysteroid dehydrogenase coupled with delta 5-delta 4 isomerase, concentration of cytochrome P-450 and the activity of the cytochrome-involving enzyme systems such as 17 alpha- and 21-hydroxylases were significantly reduced. 17 alpha-Hydroxylase activity was more effectively decreased by Fe2+ than that of 21-hydroxylase. On the other hand, activity of NADH- and NADPH-cytochrome c reductases remained unchanged or somewhat increased. Both the induction of lipid peroxidation and the decrease of the enzyme activities were prevented by alpha-tocopherol and N,N' -diphenyl-rho-phenylenediamine.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Imataka H,Suzuki K,Tamaoki B

doi

10.1016/0006-291x(85)90096-8

subject

Has Abstract

pub_date

1985-04-30 00:00:00

pages

657-63

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(85)90096-8

journal_volume

128

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Characterization of a new lignin peroxidase gene (GLG6) from Phanerochaete chrysosporium.

    abstract：:Sequence analysis of a new lignin peroxidase (LIP) gene, GLG6, from P. chrysosporium showed that it encodes a mature LIP protein with a predicted Mr of 36,454. A 28 aa signal peptide precedes the mature protein. The coding region of GLG6 is interrupted by nine introns ranging in size from 50-57 bp. GLG6 encoded-LIP ha...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80884-8

    authors： Naidu PS,Zhang YZ,Reddy CA

    更新日期：1990-12-31 00:00:00

  • Biochemical deficiencies of coenzyme Q10 in HIV-infection and exploratory treatment.

    abstract：:AIDS patients (2 groups) had a blood deficiency (p less than 0.001) of coenzyme Q10 vs. 2 control groups. AIDS patients had a greater deficiency (p less than 0.01) than ARC patients. ARC patients had a deficiency (p less than 0.05) vs. control. HIV-infected patients had a deficiency (p less than 0.05) vs. control. The...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)81179-3

    authors： Folkers K,Langsjoen P,Nara Y,Muratsu K,Komorowski J,Richardson PC,Smith TH

    更新日期：1988-06-16 00:00:00

  • Rhodamine 123 inhibits import of rat liver mitochondrial transhydrogenase.

    abstract：:Rhodamine 123, a laser dye, has been demonstrated to inhibit import of the precursor to pyridine dinucleotide transhydrogenase into mitochondria in rat liver cells. When rat hepatocytes were labeled with 35[S] methionine in the presence of 0.4 mM rhodamine 123, the precursor to transhydrogenase was found to have a hal...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(87)80534-x

    authors： Lubin IM,Wu LN,Wuthier RE,Fisher RR

    更新日期：1987-04-14 00:00:00

  • R-spondin 2 facilitates differentiation of proliferating chondrocytes into hypertrophic chondrocytes by enhancing Wnt/β-catenin signaling in endochondral ossification.

    abstract：:Endochondral ossification is a crucial process for longitudinal growth of bones. Differentiating chondrocytes in growth cartilage form four sequential zones of proliferation, alignment into column, hypertrophy, and substitution of chondrocytes with osteoblasts. Wnt/β-catenin signaling is essential for differentiation ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.03.089

    authors： Takegami Y,Ohkawara B,Ito M,Masuda A,Nakashima H,Ishiguro N,Ohno K

    更新日期：2016-04-22 00:00:00

  • Purification and characterization of human recombinant insulin-like growth factor binding protein 3 expressed in Chinese hamster ovary cells.

    abstract：:Recombinant human insulin-like growth factor binding protein 3 (hIGFBP-3) stably expressed in chinese hamster ovary cells (CHO cells) has been purified to homogeneity from serum-free culture media. The purified protein migrates as a doublet (45/43 kDa) upon SDS-PAGE. The purified recombinant hIGFBP-3 is fully active a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)90154-y

    authors： Tressel TJ,Tatsuno GP,Spratt K,Sommer A

    更新日期：1991-07-31 00:00:00

  • Identification of an arginine vasopressin-like diuretic hormone from Locusta migratoria.

    abstract：:We have identified two neuropeptides (F1 and F2) from suboesophageal and thoracic ganglia of Locusta migratoria, which we isolated earlier based on their immunological similarity to arginine vasopressin. The more abundant and hydrophilic factor, F1, has sequence Cys-Leu-Ile-Thr-Asn-Cys-Pro-Arg-Gly-NH2, but its biologi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)91621-4

    authors： Proux JP,Miller CA,Li JP,Carney RL,Girardie A,Delaage M,Schooley DA

    更新日期：1987-11-30 00:00:00

  • Multi-strand binding of nuclear factors to a repressor of mouse mammary tumor virus transcription can be distinguished kinetically.

    abstract：:NRE1 is a DNA sequence element in the long terminal repeat of mouse mammary tumor virus that represses viral transcription in mature T cells. In addition to double-stranded binding activity, factors in Jurkat T cell nuclear extracts bind specifically to each of the two single-strands of NRE1. Here we show that binding...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.1514

    authors： Rodda DJ,Giffin W,Haché RJ

    更新日期：1995-04-06 00:00:00

  • Salmon cartilage proteoglycan modulates cytokine responses to Escherichia coli in mouse macrophages.

    abstract：:Proteoglycans (PGs) are complex glycohydrates, which are composed of core proteins and glycosaminoglycans and widely distributed in connective tissues and on the cell surface of mammalian tissues. We investigated the effect of PG extracted from salmon cartilage on cytokine responses to stimulation with heat-killed Esc...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.10.146

    authors： Sashinami H,Takagaki K,Nakane A

    更新日期：2006-12-29 00:00:00

  • H1-histaminergic activation stimulates inositol-1-phosphate accumulation in chromaffin cells.

    abstract：:Adrenal medullary chromaffin cells maintained in vitro were prelabeled with [3H]inositol and the accumulation of [3H]inositol-1-phosphate, was determined following stimulation with a variety of pharmacological agents. Carbachol, bradykinin, and histamine produced significantly greater accumulation of [3H] inositol-1-p...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(86)90031-8

    authors： Noble EP,Bommer M,Sincini E,Costa T,Herz A

    更新日期：1986-03-13 00:00:00

  • Implication of novel biochemical property of beta-amyloid.

    abstract：:Alzheimer disease (AD) is a heterogeneous disorder with a variety of molecular pathologies converging predominantly on abnormal amyloid deposition particularly in the brain. beta-Amyloid aggregation into senile plaques is one of the pathological hallmarks of AD. beta-Amyloid is generated by a proteolytic cleavage of a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1999.2024

    authors： Elbaum D,Brzyska M,Bacia A,Alkon DL

    更新日期：2000-01-27 00:00:00

  • Expression and characterization of the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II using the baculovirus expression system.

    abstract：:Sf9 cells infected with the recombinant mouse CaMKII-alpha (Ca2+/calmodulin dependent kinase II) baculovirus expressed 12-15 mg of MCaMKII-alpha per liter of cells. Approximately 50% of the MCaMKII-alpha activity could be purified using a CaM-Sepharose affinity column. The purified MCaMKII-alpha had a M(rapp) of 50 kD...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80074-9

    authors： Brickey DA,Colbran RJ,Fong YL,Soderling TR

    更新日期：1990-12-14 00:00:00

  • Heparin increases mRNA levels of thrombospondin but not fibronectin in human vascular smooth muscle cells.

    abstract：:The effects of heparin (180 micrograms/ml) on steady state mRNA levels for fibronectin, thrombospondin, actin and collagen types I and III were investigated in human umbilical artery smooth muscle cells. Heparin caused a 120% increase in thrombospondin mRNA levels and a 60% and 180% increase in the mRNA levels of proc...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)90786-9

    authors： Lyons-Giordano B,Brinker JM,Kefalides NA

    更新日期：1989-08-15 00:00:00

  • The role of wogonin in controlling SOCS3 expression in neuronal cells.

    abstract：:The mechanism underlying the wogonin-mediated increase in the expression of suppressor of cytokine signaling 3 (SOCS3) is unclear. Promoter deletion assay results revealed that wogonin-induced SOCS3 expression is dependent on the AP-1 consensus sequences and two STAT responsive elements (TTACAAGAA and TTCCAGGAA) in th...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.07.018

    authors： Nam KW,Chae S,Song HY,Mar W,Han MD

    更新日期：2014-08-08 00:00:00

  • Alpha7 nicotinic acetylcholine receptor activation protects against myocardial reperfusion injury through modulation of autophagy.

    abstract：:Alpha7 nicotinic acetylcholine receptor (α7nAChR) activation alleviates myocardial ischemia/reperfusion (MI/R) injury. However, the underlying mechanisms remain unclear. Here, we investigated the role of autophagy in α7nAChR-mediated cardioprotection and the molecular mechanisms involved. Activating α7nAChR with PNU-2...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.04.077

    authors： Hou Z,Zhou Y,Yang H,Liu Y,Mao X,Qin X,Li X,Zhang X,Hu Y

    更新日期：2018-06-02 00:00:00

  • TSPA as a novel ATF6α translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice.

    abstract：:Activating transcription factor 6α (ATF6α) as a transducer in unfolded protein response (UPR), plays an important role in liver glucose metabolism and insulin resistance. Thus, targeting ATF6α activation has been proposed to be a potential strategy for anti-T2DM drug discovery. Here, we determined that small molecule ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.04.025

    authors： Zhou T,Cheng Y,Yan W,Shi X,Xu X,Zhou J,Li J,Chen J,Shen X

    更新日期：2018-05-23 00:00:00

  • Transcriptomic and cellular analyses of CRISPR/Cas9-mediated edition of FASN show inhibition of aggressive characteristics in breast cancer cells.

    abstract：:Several genes are significantly mutated in breast cancer but only a small percentage of mutations are well-known to contribute to cancer development. FASN is involved in de novo lipogenesis and the regulation of ERα signaling. However, the effect of genetic mutations affecting FASN in breast cancer has not thoroughly ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2020.05.172

    authors： Gonzalez-Salinas F,Rojo R,Martinez-Amador C,Herrera-Gamboa J,Trevino V

    更新日期：2020-08-20 00:00:00

  • Expression of PrP mRNA is regulated by a fragment of MRP8 in human fibroblasts.

    abstract：:Prion protein (PrPc) is expressed in many tissues, both in human and animals. The scrapie isoform of PrPc has been shown to cause neurodegeneration. In other studies it has been demonstrated that overexpression of the PrP gene can result in nonneuronal tissue degradation. Little is known, however, about the normal fun...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.6575

    authors： Kniazeva M,Orman R,Terranova VP

    更新日期：1997-05-08 00:00:00

  • Probing a CMP-Kdn synthetase by 1H, 31P, and STD NMR spectroscopy.

    abstract：:CMP-Kdn synthetase catalyses the reaction of sialic acids (Sia) and cytidine-5'-triphosphate (CTP) to the corresponding activated sugar nucleotide CMP-Sia and pyrophosphate PP(i). STD NMR experiments of a recombinant nucleotide cytidine-5'-monophosphate-3-deoxy-d-glycero-d-galacto-nonulosonic acid synthetase (CMP-Kdn ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.12.040

    authors： Haselhorst T,Münster-Kühnel AK,Stolz A,Oschlies M,Tiralongo J,Kitajima K,Gerardy-Schahn R,von Itzstein M

    更新日期：2005-02-11 00:00:00

  • Methylene blue induces an analgesic effect by significantly decreasing neural firing rates and improves pain behaviors in rats.

    abstract：:Methylene blue (MB) is a blue cationic thiazine dye and currently used in different medical settings. Notably, there have been several attempts to introduce MB for attenuating pain in the last decade. Some clinical studies reported remarkable results, which, however, have been much debated. In addition, accumulating e...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2021.01.008

    authors： Lee SW,Moon SW,Park JS,Suh HR,Han HC

    更新日期：2021-01-16 00:00:00

  • Identification of a sphingosine-sensitive Ca2+ channel in the plasma membrane of Leishmania mexicana.

    abstract：:The disruption of the intracellular Ca(2+) homeostasis of Leishmania mexicana represents a major target for the action of drugs, such as amiodarone and miltefosine. However, little is known about the mechanism of Ca(2+) entry to these cells. Here we show the presence of a Ca(2+) channel in the plasma membrane of these...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.12.033

    authors： Benaim G,García-Marchán Y,Reyes C,Uzcanga G,Figarella K

    更新日期：2013-01-18 00:00:00

  • Retardation of cell growth by avian reovirus p17 through the activation of p53 pathway.

    abstract：:The second open reading frame of avian reovirus S1 gene segment encodes a 17 kDa non-structural protein, named p17. The biological role of p17 is fully unknown so far. Using trypan blue dye exclusion and MTT assay, we demonstrated that the ectopic expression of p17 results in the reduction of viable cell number and ce...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.08.149

    authors： Liu HJ,Lin PY,Lee JW,Hsu HY,Shih WL

    更新日期：2005-10-21 00:00:00

  • LncRNA PCAT6 promotes tumor progression in osteosarcoma via activation of TGF-β pathway by sponging miR-185-5p.

    abstract：:Long noncoding RNAs (lncRNAs) play crucial roles in tumor development of osteosarcoma (OS). LncRNA PCAT6 was involved in the progression of multiple human cancers. However, the biological function of PCAT6 in OS remains largely unknown. We found that PCAT6 was elevated in OS tissues relative to that in their adjacent ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.10.136

    authors： Zhu C,Huang L,Xu F,Li P,Li P,Hu F

    更新日期：2020-01-08 00:00:00

  • Heterogeneity of insulin-like growth factor-I affinity for the insulin-like growth factor-II receptor: comparison of natural, synthetic and recombinant DNA-derived insulin-like growth factor-I.

    abstract：:Although insulin-like growth factors (IGF) I and II bind with high affinity to structurally discrete receptors, they bind with a lesser affinity to each other's receptor. We have evaluated the affinity of five different IGF-I preparations (three natural IGF-I preparations, one synthetic preparation, and one recombinan...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)90650-4

    authors： Rosenfeld RG,Conover CA,Hodges D,Lee PD,Misra P,Hintz RL,Li CH

    更新日期：1987-02-27 00:00:00

  • The carbohydrate specificity of conglutinin and its homology to proteins in the hepatic lectin family.

    abstract：:Inhibition experiments with D-mannose oligosaccharides establish that conglutinin recognises terminal alpha 1----2 mannobiosyl units present in the glycopeptide of the alpha-chain of the complement component C3b. On the basis of its three domain structure and the homology of its N-terminal amino-acid sequence to that ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)91402-1

    authors： Young NM,Leon MA

    更新日期：1987-03-13 00:00:00

  • Role of p120-catenin in the morphological changes of endothelial cells exposed to fluid shear stress.

    abstract：:p120-Catenin is known to play important roles in cell-cell adhesion stability by binding to cadherin and morphological changes of cells by regulating small RhoGTPase activities. Although the expression and binding states of p120-catenin are thought to dynamically change due to morphological adaptation of endothelial c...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.06.092

    authors： Sakamoto N,Segawa K,Kanzaki M,Ohashi T,Sato M

    更新日期：2010-07-30 00:00:00

  • Morquio disease: isolation, characterization and expression of full-length cDNA for human N-acetylgalactosamine-6-sulfate sulfatase.

    abstract：:We cloned and sequenced a full-length cDNA of human placental N-acetylgalactosamine-6-sulfate sulfatase, the enzyme deficient in Morquio disease. The 2339-nucleotide sequence contained 1566 nucleotides which encoded a polypeptide of 522 amino acid residues. The deduced amino acid sequence was composed of a 26-amino ac...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91244-7

    authors： Tomatsu S,Fukuda S,Masue M,Sukegawa K,Fukao T,Yamagishi A,Hori T,Iwata H,Ogawa T,Nakashima Y

    更新日期：1991-12-16 00:00:00

  • Escherichia coli mRNAs with strong Shine/Dalgarno sequences also contain 5' end sequences complementary to domain # 17 on the 16S ribosomal RNA.

    abstract：:A well-established feature of the translation initiation region, which attracts the ribosomes to the prokaryotic mRNAs, is a purine rich area called Shine/Dalgarno sequence (SD). There are examples of various other sequences, which despite having no similarity to an SD sequence are capable of enhancing and/or initiati...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.02.169

    authors： Golshani A,Krogan NJ,Xu J,Pacal M,Yang XC,Ivanov I,Providenti MA,Ganoza MC,Ivanov IG,AbouHaidar MG

    更新日期：2004-04-16 00:00:00

  • Thermodynamic and NMR analyses of NADPH binding to lipocalin-type prostaglandin D synthase.

    abstract：:Lipocalin-type prostaglandin D synthase (L-PGDS) is one of the most abundant proteins in human cerebrospinal fluid (CSF) with dual functions as a prostaglandin D2 (PGD2) synthase and a transporter of lipophilic ligands. Recent studies revealed that L-PGDS plays important roles in protecting against various neuronal di...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.10.124

    authors： Qin S,Shimamoto S,Maruno T,Kobayashi Y,Kawahara K,Yoshida T,Ohkubo T

    更新日期：2015-12-04 00:00:00

  • Effect of schisanhenol on the antitumor activity of adriamycin.

    abstract：:Schisanhenol (Sal) did not diminish the antitumor activity of adriamycin in mice bearing P388 ascites tumor. Sal did not antagonize the suppressive effect of adriamycin on DNA synthesis and cell proliferation in an L1210 ascitic tumor cell culture. Furthermore, Sal at the concentration of 0.1, 0.25, or 1 mM accelerate...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91800-r

    authors： Lin TJ,Liu GT

    更新日期：1991-07-15 00:00:00

  • Arabidopsis chloroplast chaperonin 10 is a calmodulin-binding protein.

    abstract：:Calcium regulates diverse cellular activities in plants through the action of calmodulin (CaM). By using (35)S-labeled CaM to screen an Arabidopsis seedling cDNA expression library, a cDNA designated as AtCh-CPN10 (Arabidopsis thaliana chloroplast chaperonin 10) was cloned. Chloroplast CPN10, a nuclear-encoded protein...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.3335

    authors： Yang T,Poovaiah BW

    更新日期：2000-08-28 00:00:00