Ethylene oxide sensitivity in hemodialysis patients.

Abstract:

:Sera from 138 patients who had experienced hypersensitivity-type reactions while on hemodialysis (reactors) were examined retrospectively by the radioallergosorbent test (RAST) for specific IgE antibody to ethylene oxide (ETO). Seventy-eight hemodialysis patients without a history of reaction were also evaluated as controls. Elevated serum RAST values (greater than 2.0) were more common in reactors (63%) than in controls (11%, p less than 0.001). In a second study, RAST assays were performed using human serum albumin conjugated to ETO (HSA-ETO) as antigen and also using a concentrate of fluid used to rinse ETO-sterilized dialyzers ("dialyzer extract") as antigen. The RAST ratios obtained with HSA-ETO were similar to those obtained using the dialyzer extract (rank order correlation coefficient = 0.829, p less than 0.001). In a third study, RAST inhibition was demonstrated both by HSA-ETO and dialyzer extract. Our results, extending previously published reports, suggest that hypersensitivity to ETO might play an important role in hemodialysis-associated hypersensitivity-type reactions.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Pearson F,Bruszer G,Lee W,Sagona M,Sargent H,Woods E,Dolovich J,Caruana R

doi

10.1111/j.1525-1594.1987.tb02638.x

subject

Has Abstract

pub_date

1987-04-01 00:00:00

pages

100-3

issue

2

eissn

0160-564X

issn

1525-1594

journal_volume

11

pub_type

杂志文章
  • Optimal continuous retrograde coronary perfusion flow rate with beating heart in normal temperature.

    abstract:PURPOSE:We were led to the premise that with retrograde oxygenated blood perfusion, it would be possible to perform operations on the beating heart. METHODS:The experiment consisted of two stages: procedure 1 and 2. In procedure 1, six pigs were used. Retrograde perfusion flow was controlled to be in the range of 5.0-...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2004.47279.x

    authors: Tsukioka T,Tomita S,Watanabe G,Takemura H

    更新日期:2004-03-01 00:00:00

  • Heparin coating of small-caliber decellularized xenografts reduces macrophage infiltration and intimal hyperplasia.

    abstract::Small-caliber decellularized xenografts with surface heparin coating are known to reduce in vivo thrombogenicity. This study was performed to examine whether heparin coating on the small-caliber decellularized xenografts would reduce macrophage infiltration and intimal hyperplasia. In a rabbit model of bilateral carot...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00748.x

    authors: Cai WW,Gu YJ,Wang XN,Chen CZ

    更新日期:2009-06-01 00:00:00

  • Effect of age on calcification of poly(hydroxyethyl methacrylate) in animals.

    abstract::The effect of age on the calcification of biomaterials was studied by the subcutaneous implantation of poly(hydroxyethyl methacrylate) hydrogel in rats. The hydrogel sheets were implanted in rats 6, 12, 24, and 52 weeks (1 year) of age. The retrieved implants were compared and the percentage weight increase by mineral...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1985.tb04388.x

    authors: Imai Y

    更新日期:1985-08-01 00:00:00

  • Usability and safety of ventricular assist devices: human factors and design aspects.

    abstract::The purpose of this study was the investigation of the usability and ergonomics of ventricular assist devices (VADs) in everyday usage. Patients with four different VAD types were observed. After implantation, instruction, and discharge from the hospital, the patients returned on a regular basis to the outpatient clin...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00844.x

    authors: Geidl L,Zrunek P,Deckert Z,Zimpfer D,Sandner S,Wieselthaler G,Schima H

    更新日期:2009-09-01 00:00:00

  • Cell adhesive and antifouling polyvinyl chloride surfaces via wet chemical modification.

    abstract::Polyvinyl chloride (PVC) is one of the most frequently used polymers for the manufacturing of medical devices. Limitations for its usage are based upon unfavorable surface properties of the polymer including its hydrophobicity and lack of functionalities in order to increase its versatility. To address this issue, wet...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2012.01462.x

    authors: Gabriel M,Strand D,Vahl CF

    更新日期:2012-09-01 00:00:00

  • Termination of extracorporeal membrane oxygenation for cardiac support.

    abstract::The determination of when to stop extracorporeal membrane oxygenation (ECMO) rests upon demonstration of the return of adequate cardiac function to support vital organs and permit subsequent recovery. In general, patients with myocardial stun will recover function within several days. Factors that limit recovery inclu...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1999.06445.x

    authors: Steinhorn DM

    更新日期:1999-11-01 00:00:00

  • Effects of hemodynamic conditions and valve sizing on leaflet bending stress in self-expanding transcatheter aortic valve: An in vitro study.

    abstract::Transcatheter aortic valve (TAV) replacement has become a viable alternative to surgery for high and intermediate risk patients with severe aortic stenosis. This technology may extend to the younger and lower risk patients. In this population, long-term durability of the TAV is key. Increased leaflet mechanical stress...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13654

    authors: Stanová V,Zenses AS,Thollon L,Kadem L,Barragan P,Rieu R,Pibarot P

    更新日期:2020-07-01 00:00:00

  • Treatment of thyrotoxic crisis with plasmapheresis and single pass albumin dialysis: a case report.

    abstract::Thyrotoxic crisis (thyroid storm) is a life-threatening condition. Standard therapy is based on thiamazole, prednisolone, and nonselective beta-blockers. Extracorporeal plasmapheresis is an additional tool for removing circulating thyroxine in patients who do not respond quickly to conventional standard therapy. As th...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00924.x

    authors: Koball S,Hickstein H,Gloger M,Hinz M,Henschel J,Stange J,Mitzner S

    更新日期:2010-02-01 00:00:00

  • Numerical modeling of blood flow in the ventricular cavity of the artificial heart.

    abstract::The flow of blood as a viscous, Newtonian, incompressible liquid in an expanding spherical cavity with a ball-type inlet valve was examined. This type of flow can serve as a model of the phase of ventricular diastole in a sac-type artificial heart. The critical values of Reynolds numbers at which flow interruption beh...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1983.tb04170.x

    authors: Starobin IM,Zaĭko VM

    更新日期:1983-02-01 00:00:00

  • Intestinal tissue oxygenation and tumor necrosis factor-alpha release during systemic blood flow changes in pigs with left ventricular assist devices.

    abstract::We previously demonstrated that tumor necrosis factor-alpha (TNF-alpha) increased following a reduction in systemic blood flow to 60% or less of the original cardiac output using a left ventricular assist device (LVAD). The aim of this study was to investigate the effect of reducing systemic blood flow on tissue oxyge...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2001.025001053.x

    authors: Uozaki Y,Dihmis WC,Yamauchi H,Moczar M,Miyama M,Pasteau F,Tixier D,Bambang SL,Loisance DY

    更新日期:2001-01-01 00:00:00

  • Risk factor forlung infection in recipients after liver transplantation:a meta-analysis.

    abstract:OBJECTIVE:Lung infection (LI) often occurs in patients with liver transplantation (LT). This meta-analysis was conducted to determine the risk factors associated with LI after LT. METHODS:We retrieved relevant research published as of February 2020 from 8 electronic databases. The studieswere reviewed against the incl...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13826

    authors: Zhang J,He Q,Du L,Ji R,Yuan L,Zhang H,Yuan X,Shen L,Li Y

    更新日期:2020-09-26 00:00:00

  • Remote monitoring of left ventricular assist device parameters after HeartAssist-5 implantation.

    abstract::Although several left ventricular assist devices (LVADs) have been used widely, remote monitoring of LVAD parameters has been available only recently. We present our remote monitoring experience with an axial-flow LVAD (HeartAssist-5, MicroMed Cardiovascular, Inc., Houston, TX, USA). Five consecutive patients who were...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12144

    authors: Pektok E,Demirozu ZT,Arat N,Yildiz O,Oklu E,Eker D,Ece F,Ciftci C,Yazicioglu N,Bayindir O,Kucukaksu DS

    更新日期:2013-09-01 00:00:00

  • Multifunctional implantable nerve stimulator for cardiac assistance by skeletal muscle.

    abstract::Different methods are used, clinically and experimentally, to assist severely impaired heart function by means of skeletal muscle. The efficiency of these methods is restricted by skeletal muscle losing strength after transpositioning and during conditioning and not being sufficiently resistant to fatigue. This is mai...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1999.06258.x

    authors: Lanmüller H,Sauermann S,Unger E,Schnetz G,Mayr W,Bijak M,Girsch W

    更新日期:1999-04-01 00:00:00

  • The use of electrolyzed solutions for the cleaning and disinfecting of dialyzers.

    abstract::Recently, the use of electrolyzed solutions has attracted considerable interest in Japan. This study investigates the efficiency of electrolyzed solutions as disinfecting agents (DA) in the reuse of dialyzers and compares their efficiency to that of other disinfectants currently in use. The following 3 methods were em...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2000.06611.x

    authors: Tanaka N,Tanaka N,Fujisawa T,Daimon T,Fujiwara K,Yamamoto M,Abe T

    更新日期:2000-12-01 00:00:00

  • Magnetic suspension of the rotor of a ventricular assist device of mixed flow type.

    abstract::This work presents results of preliminary studies concerning application of magnetic bearing in a ventricular assist device (VAD) being developed by Dante Pazzanese Institute of Cardiology-IDPC (São Paulo, Brazil). The VAD-IDPC has a novel architecture that distinguishes from other known VADs. In this, the rotor has a...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2008.00551.x

    authors: Horikawa O,de Andrade AJ,da Silva I,Bock EG

    更新日期:2008-04-01 00:00:00

  • Kinetics of group IB and IIA phospholipase A2 during low-volume continuous hemodiafiltration in severe acute pancreatitis.

    abstract::Continuous hemodiafiltration (CHDF) has been performed for the treatment of severe acute pancreatitis. Phospholipase A2 (PLA2) is one of the important mediators which exacerbate acute pancreatitis, but whether PLA2 can be removed by CHDF is unclear. In this study, the kinetics of group IB and group IIA PLA2 was examin...

    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1525-1594.2007.00398.x

    authors: Suzuki M,Okahisa T,Sogabe M,Iwaki H,Okita Y,Ohnishi Y,Ito S

    更新日期:2007-05-01 00:00:00

  • Hepatocyte growth factor-transfected skeletal myoblasts to limit the development of postinfarction heart failure.

    abstract::Stem cells transplanted to an injured heart affect the host myocardium indirectly. The cytokine hepatocyte growth factor (HGF) may play a key role in this paracrine activity. We hypothesized that HGF-overexpressing stem cells would restore cardiac function after myocardial infarction (MI). Because there is a high rate...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2011.01328.x

    authors: Poppe A,Golsong P,Blumenthal B,von Wattenwyl R,Blanke P,Beyersdorf F,Schlensak C,Siepe M

    更新日期:2012-03-01 00:00:00

  • Physiologic control of cardiac assist devices.

    abstract::Total artificial hearts (TAHs) and biventricular assist devices (BVADs) have varying levels of acceptance and reliability, and the research on both focuses on their control mechanisms. Efforts generally aim to achieve a response to physiologic demand and left/right output balance, and beneficial cardiac output (CO) an...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1996.tb04438.x

    authors: Hall AW,Soykan O,Harken AH

    更新日期:1996-03-01 00:00:00

  • Dialysate and blood temperature during hemodialysis: comparing isothermic dialysis with a single-pass batch system.

    abstract::The Genius is a convenient single-pass batch hemodialysis system. Dialysate is heated during the preparation phase. Once the container is filled at one of the three available starting temperatures, dialysate cools spontaneously. As dialysate temperature plays an important role in hemodynamic stability, knowledge of th...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00981.x

    authors: Dhondt A,Eloot S,Verbeke F,Vanholder R

    更新日期:2010-12-01 00:00:00

  • Modified DALI LDL-apheresis using trisodium citrate anticoagulation plus bicarbonate or lactate-buffered hemofiltration substitution fluids as primers.

    abstract:BACKGROUND:DALI (direct adsorption of lipids) is the first LDL-apheresis technique able to adsorb low-density lipoprotein (LDL) and lipoproteina) directly from whole blood. In the standard procedure, acid citrate dextrose (ACD-A) is used as anticoagulation and the adsorber is rinsed with a specially manufactured primin...

    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1525-1594.2003.07104.x

    authors: Bosch T,Wendler T,Maschke H

    更新日期:2003-06-01 00:00:00

  • Comparison of a New Miniaturized Extracorporeal Membrane Oxygenation System With Integrated Rotary Blood Pump to a Standard System in a Porcine Model of Acute Lung Injury.

    abstract::Extracorporeal membrane oxygenation (ECMO) is used for severe acute respiratory distress syndrome. However, available ECMO systems are large and not well designed for fast delivery, emergency implantation, and interhospital transfer. Therefore, a new miniaturized oxygenator with integrated rotary blood pump (ILIAS) wa...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12611

    authors: Pilarczyk K,Heckmann J,Lyskawa K,Strauß A,Haake N,Wiese I,Jakob H,Kamler M,Pizanis N

    更新日期:2016-07-01 00:00:00

  • Paracorporeal artificial heart in postoperative heart failure.

    abstract::A pneumatically driven artificial heart with a tubular silicone rubber membrane and disc valves was used for functional heart replacement in the paracorporeal mode. A fluidic drive system allows adjustment of the heart rate, positive and negative pressures and systole/diastole ratio. Since August, 1977, the artificial...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1978.tb03465.x

    authors: Turina MT,Bosio R,Senning A

    更新日期:1978-08-01 00:00:00

  • Fluid-Structure Interactions Analysis of Shear-Induced Modulation of a Mesenchymal Stem Cell: An Image-Based Study.

    abstract::Although effects of biochemical modulation of stem cells have been widely investigated, only recent advances have been made in the identification of mechanical conditioning on cell signaling pathways. Experimental investigations quantifying the micromechanical environment of mesenchymal stem cells (MSCs) are challengi...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12547

    authors: Ghaemi RV,Vahidi B,Sabour MH,Haghighipour N,Alihemmati Z

    更新日期:2016-03-01 00:00:00

  • Effect of Continuous-Flow Mechanical Circulatory Support on Microvasculature Remodeling in the Failing Heart.

    abstract::Left ventricle (LV) unloading caused by a left ventricular assist device (LVAD) has been shown to enhance reverse LV remodeling in end-stage cardiomyopathy. Several reports consistently suggest that a pulsatile-flow LVAD has more profound effects compared to continuous-flow LVAD, though the responsible mechanisms are ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13348

    authors: Saito T,Miyagawa S,Toda K,Yoshikawa Y,Fukushima S,Saito S,Yoshioka D,Sakata Y,Daimon T,Sawa Y

    更新日期:2019-04-01 00:00:00

  • HeartWare Ventricular Assist Device Implantation for Pediatric Heart Failure-A Single Center Approach.

    abstract::While pediatric HeartWare HVAD application has increased, determining candidacy and timing for initiation of pediatric VAD support has remained a challenge. We present our experience with a systematic approach to HVAD implantation as a bridge to pediatric heart transplantation. We performed a retrospective, single cen...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13344

    authors: Nelson McMillan K,Hibino N,Brown EE,Wadia R,Hunt EA,Marshall C,Alvarez-Machado M,Alejo D,Coulson JD,Ravekes W,Vricella LA

    更新日期:2019-01-01 00:00:00

  • Miniaturization of a magnetically levitated axial flow blood pump.

    abstract::This article introduces a unique miniaturization process of a magnetically levitated axial flow blood pump from a functional prototype to a pump suitable for animal trials. Through COMSOL three-dimensional finite element analysis and experimental verification, the hybrid magnetic bearings of the pump have been miniatu...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2010.01077.x

    authors: Cheng S,Olles MW,Olsen DB,Joyce LD,Day SW

    更新日期:2010-10-01 00:00:00

  • Is ionic dialysance a valid parameter for quantification of dialysis efficiency?

    abstract::The on-line measurement during hemodialysis of ionic dialysance provides an estimation of urea clearance with a good and already proven correlation. Some discrepancies remain controversial, and the influence of the dialyzer membrane is still being debated. Eighty-eight measurements of ionic dialysance (ID) were perfor...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1998.06062.x

    authors: Mercadal L,Petitclerc T,Jaudon MC,Béné B,Goux N,Jacobs C

    更新日期:1998-12-01 00:00:00

  • Pump power loss and heat generation in a pivot bearing-supported Gyro centrifugal pump (C1E3).

    abstract::Pump power loss is defined as input power that is not used for the output work of the pump. Less pump power loss means a higher pump efficiency. A common opinion is that the pump power loss is closely related to heat generation of the pump, which may affect not only the endurance of pump materials, but also blood dama...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1996.tb04542.x

    authors: Takami Y,Nakazawa T,Makinouchi K,Glueck J,Ohara Y,Benkowski RJ,Nosé Y

    更新日期:1996-07-01 00:00:00

  • Intravenous prostacyclin mitigates inhaled nitric oxide rebound effect: A case control study.

    abstract::Although extracorporeal membrane oxygenation (ECMO) improves oxygenation, pulmonary vascular resistance may be increased due to endothelial function impairment. Inhaled nitric oxide (iNO) is increasingly used for treatment of pulmonary hypertension after surgical repair of congenital heart defects, with or without ECM...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1999.06448.x

    authors: Hermon M,Golej J,Burda G,Marx M,Trittenwein G,Pollak A

    更新日期:1999-11-01 00:00:00

  • Intra-Aortic Balloon Pump Support in the Isolated Beating Porcine Heart in Nonischemic and Ischemic Pump Failure.

    abstract::The blood pressure changes induced by the intra-aortic balloon pump (IABP) are expected to create clinical improvement in terms of coronary perfusion and myocardial oxygen consumption. However, the measured effects reported in literature are inconsistent. The aim of this study was to investigate the influence of ische...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12470

    authors: Schampaert S,van Nunen LX,Pijls NH,Rutten MC,van Tuijl S,van de Vosse FN,van 't Veer M

    更新日期:2015-11-01 00:00:00