Improvement of direct agglutination test (DAT) for laboratory diagnosis of visceral leishmaniasis in Brazil.

abstract：:Sera of 173 individuals living in a malaria endemic region in Upper Volta (Donsé village) were screened for the presence of 14 auto-antibodies by the indirect immunofluorescent and/or passive haemagglutination techniques. At least one auto-antibody (AAb) was detected in sera of 72% (124 out of 173) subjects. No differ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Daniel-Ribeiro C,Druilhe P,Monjour L,Homberg JC,Gentilini M

更新日期：1983-01-01 00:00:00

abstract：:In Malawi, where high levels of chloroquine resistance were shown using a modified 7-day in vivo test, amodiaquine and pyrimethamine-sulfadoxine were evaluated as alternative initial therapies for Plasmodium falciparum infections in children under 5 years old. Therapy success rates, judged by parasite clearance by day...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Heymann DL,Khoromana CO,Wirima JJ,Campbell CC

更新日期：1987-01-01 00:00:00

abstract：:Persistent diarrhoea is a major cause of morbidity and mortality in AIDS patients, and consequently an important public health problem in sub-Saharan Africa. Although intestinal protozoa and bacteria are detected in many of these patients, a substantial proportion of disease remains unexplained even after intensive in...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kelly P,Hicks S,Oloya J,Mwansa J,Sikakwa L,Zulu I,Phillips A

更新日期：2003-09-01 00:00:00

abstract：:Information on the prevalence, incidence, and geographical distribution of malaria in Zimbabwe is reviewed. Malaria control operations carried out during the last 30 years are briefly described together with available information of their impact on malaria. From 1972 to 1981, 51,962 positive blood slides were submitte...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Taylor P,Mutambu SL

更新日期：1986-01-01 00:00:00

abstract：:Recent investigations on the distribution of human and canine leishmaniasis, and on the vectors and wild reservoirs of the disease in foci in Tuscany have stimulated a retrospective evaluation of human leishmaniasis of the whole region. From a study of the literature, of statistical reports (ISTAT) and of unpublished ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Bettini S,Maroli M,Gradoni L

更新日期：1981-01-01 00:00:00

abstract：:Malaria remains an important health problem in Bangladesh, with approximately 14 million people at risk. Antimalarial drug resistance is a major obstacle to the control of malaria in endemic countries. In 2012, Bangladesh reported an estimated 29 522 malaria episodes, of which 94% were reported as being caused by Plas...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Haque U,Glass GE,Haque W,Islam N,Roy S,Karim J,Noedl H

更新日期：2013-12-01 00:00:00

abstract：:To help to elucidate the changes induced by Trypanosoma brucei gambiense in the central nervous system (CNS) in advanced sleeping sickness patients, levels of interleukin-1 (IL-1) and prostaglandins D2 (PGD2) and E2 (PGE2) were measured by radioimmunoassay in the cerebrospinal fluid (CSF) from 24 patients diagnosed on...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pentreath VW,Rees K,Owolabi OA,Philip KA,Doua F

更新日期：1990-11-01 00:00:00

abstract：:Mice immunized with purified antigen preparations produced in Escherichia coli and containing the glutathione S-transferase (GST) isoenzyme of Schistosoma japonicum (Sj26) can be partially resistant to infection with this parasite. Maximum resistance was approximately 50% and no protection was obtained in BALB/c mice,...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mitchell GF,Garcia EG,Davern KM,Tiu WU,Smith DB

更新日期：1988-01-01 00:00:00

abstract：:Infantile visceral leishmaniasis (VL) was first reported from north Pakistan over 3 decades age in the remote valleys of the western Himalayas. These foci were reported as being completely devoid of domestic dogs. The later emergence of sporadic cases of infantile VL in the sub-Himalayan region of the country, where d...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Rab MA,Frame IA,Evans DA

更新日期：1995-11-01 00:00:00

abstract：:Central nervous system involvement due to toxoplasmosis in an immunocompetent host is very rare. We report a case of an immunocompetent patient who presented with suspected tuberculous meningoencephalitis but showed no clinical response to antitubercular therapy. Later, toxoplasmic meningoencephalitis was proved by po...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kaushik RM,Mahajan SK,Sharma A,Kaushik R,Kukreti R

更新日期：2005-11-01 00:00:00

abstract：:Niclosamide was used to interrupt transmission of Schistosoma haematobium by Bulinus senegalensis in seasonal rainwater pools for a period of three years. Snail populations were progressively reduced to approximately 1% of the numbers in untreated pools. There was little or no evidence of acquisition of new infection ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Goll PH,Wilkins HA,Marshall TF

更新日期：1984-01-01 00:00:00

abstract：:Eight weeks following infection with Schistosoma mansoni ICR strain mice showed much more marked hepatic fibrosis than did C57BL/6 mice or hamsters. None the less, extracts of the hepatic granulomata of these animals had similar fibroblast stimulating activity when assayed in vitro. ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Cheever AW,Barral-Netto M

更新日期：1985-01-01 00:00:00

abstract：:The involvement of the lung in 13 cases of human visceral leishmaniasis was studied. Interstitial pneumonitis with mononuclear cells was found in 76.8% of the cases; 53.8% also had foci of septal fibrosis. Leishmania were seen within macrophages in 3 cases only. However, all 10 interstitial pneumonitis cases showed PA...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Duarte MI,da Matta VL,Corbett CE,Laurenti MD,Chebabo R,Goto H

更新日期：1989-01-01 00:00:00

abstract：:The liver fluke Opisthorchis felineus is a member of the triad of epidemiologically important liver fluke species belonging to the family Opisthorchiidae and the major agent causing opisthorchiasis over a vast territory, covering Russia, Kazakhstan and several European countries. The similarity between the diseases ca...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pakharukova MY,Mordvinov VA

更新日期：2016-01-01 00:00:00

abstract：:The development and application of interventions for the control of vector-borne zoonoses requires broad understanding of epidemiological linkages between vector, animal infection and human infection. However, there are significant gaps in our understanding of these linkages and a lack of appropriate data poses a cons...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Wardrop NA

更新日期：2016-02-01 00:00:00

abstract：:The results of an autopsy study of Opisthorchis viverrini infection in 181 accident subjects in northeast Thailand are presented. The age-prevalence profiles were similar whether determined by faecal examination for parasite eggs or by recovery of worms from the liver. The prevalence increased rapidly with age and rea...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sithithaworn P,Tesana S,Pipitgool V,Kaewkes S,Thaiklar K,Pairojkul C,Sripa B,Paupairoj A,Sanpitak P,Aranyanat C

更新日期：1991-11-01 00:00:00

abstract：:Data on malaria transmission intensity and prevalences of asexual parasites and of gametocytes were obtained in an urban district of Yaoundé, Cameroon. The transmission level from mosquito to human was determined by indoor night capture of mosquitoes on human volunteers, revealing a calculated entomological inoculatio...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： van der Kolk M,Tebo AE,Nimpaye H,Ndombol DN,Sauerwein RW,Eling WM

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Bacteria are sources of numerous molecules used in treatment of infectious diseases. We investigated effects of molecules produced by 26 Pseudomonas aeruginosa strains against infection of mammalian cell cultures with Trypanosoma cruzi, the aetiological agent of Chagas disease. METHODS:Vero cells were infec...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sass G,Miller Conrad LC,Nguyen TH,Stevens DA

更新日期：2020-07-01 00:00:00

abstract：:This paper provides an overview of the methods in which geographic information systems (GIS) and remote sensing (RS) technology have been used to visualise and analyse data related to vectorborne diseases (VBD) in West Africa and to discuss the potential for these approaches to be routinely included in future studies ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ratmanov P,Mediannikov O,Raoult D

更新日期：2013-05-01 00:00:00

abstract：:Antibody to Ebola virus was found in 14 (1.2%) of 1147 human sera collected in Gabon in 1981-1997. Six seropositive subjects were bled in the northeast in 1991, more than 3 years prior to recognition of the first known outbreak of Ebola haemorrhagic fever (EHF), whilst eight came from the southwest where the disease h...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Lahm SA,Kombila M,Swanepoel R,Barnes RF

更新日期：2007-01-01 00:00:00

abstract：:We used a recently developed sandwich enzyme-linked immunosorbent assay to determine the kinetics of Schistosoma mansoni circulating soluble egg antigen (CSEA) after chemotherapy and compared these with previously determined levels of circulating cathodic antigen (CCA). Urine samples were collected from 35 Egyptian pa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Nibbeling HA,Van Lieshout L,Deelder AM

更新日期：1998-11-01 00:00:00

abstract：:A new antihookworm compound, C.9333 Go./CGP 4540, was evaluated clinically in 65 adult patients with hookworm infection. Several dosage schedules were evaluated to determine an effective, well tolerated and convenient regime. The lowest effective dose was 125 mg administered at four-hourly intervals for three doses. T...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Vakil BJ,Dalal NJ,Shah PN

更新日期：1977-01-01 00:00:00

abstract：:Intrathecal cytokine levels and blood-cerebrospinal fluid (CSF) barrier function were studied in 91 Trypanosoma brucei rhodesiense-infected patients. The CSF concentration of the cellular immune activation marker neopterin and the cytokines IL-6 and IL-10 were increased over control and post-treatment levels in all pa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Maclean L,Odiit M,Sternberg JM

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:We sought to determine the prevalence of drug resistant TB among outpatients initiating TB treatment in Lilongwe, Malawi. METHODS:This was a prospective cohort study of patients 18 years and older initiating TB treatment at Martin Preuss Centre, the primary integrated HIV/TB clinic in Lilongwe, Malawi, from...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Barnett B,Gokhale RH,Krysiak R,Kanyemba C,Chikaonda T,Bokosi M,Mukuzunga C,Saidi F,Phiri S,Hoffman IF,Hosseinipour MC

更新日期：2015-12-01 00:00:00

abstract：:The optimum treatment for louse-borne relapsing fever (LBRF) has not been fully established. Eliminating spirochetes is often associated with the potentially lethal Jarisch-Herxheimer reaction (JHR). The objective of this meta-analysis was to review the evidence supporting the use of antibiotics usually employed for t...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Guerrier G,Doherty T

更新日期：2011-09-01 00:00:00

abstract：:We present a case report from 2001 of the first parasitologically confirmed case of acute Chagas disease in Suriname. The patient had never left Suriname, and was probably infected by an adventitious species of Panstrongylus in his house in the capital city, Paramaribo. The patient was treated with nifurtimox, and app...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Oostburg BF,Anijs JE,Oehlers GP,Hiwat HO,Burke-Hermelijn SM

更新日期：2003-03-01 00:00:00

abstract：:In 1991, a study on Wuchereria bancrofti microfilariae (mf) and infection rates was carried out in the human and mosquito populations of a Polynesian village where, 10 years before, the mf prevalence rate was 6.4% and twice-yearly mass treatment with 3 mg/kg of diethylcarbamazine (DEC) was interrupted. Venous blood sa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Cartel JL,Nguyen NL,Spiegel A,Moulia-Pelat JP,Plichart R,Martin PM,Manuellan AB,Lardeux F

更新日期：1992-07-01 00:00:00

abstract：:Young African children with severe malaria are given quinine using a regimen designed for Thai adults. We measured quinine in the blood, plasma and plasma water of young children in Kenya after rapid intravenous and intramuscular dosing, and calculated the therapeutic range of unbound quinine. The peak plasma quinine ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Winstanley P,Newton C,Watkins W,Mberu E,Ward S,Warn P,Mwangi I,Waruiru C,Pasvol G,Warrell D

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Antibiotic resistance is an increasing problem, particularly in countries where antibiotic use is frequently not controlled. The aim of this study was to analyse the prevalence of the molecular mechanisms of quinolone-resistance in E. coli isolated from faeces of healthy Peruvian children or those presenting...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pons MJ,Mosquito S,Gomes C,Del Valle LJ,Ochoa TJ,Ruiz J

更新日期：2014-01-01 00:00:00

abstract：:The commercial dot-blot enzyme-linked immunosorbent assay Dip-S-Ticks dipstick test was compared with the indirect immunoperoxidase (IIP) and Weil-Felix (WF) tests for the diagnosis of scrub typhus, using the indirect immunofluorescent antibody test (IFA) as the reference standard. With a panel of 117 positive and 75 ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pradutkanchana J,Silpapojakul K,Paxton H,Pradutkanchana S,Kelly DJ,Strickman D

更新日期：1997-07-01 00:00:00