Fibroblast stimulating activity of extracts of hepatic granulomata of Schistosoma mansoni-infected rodents with marked or slight hepatic fibrosis.

abstract：:This paper reports the isolation and characterization of a complementary deoxyribonucleic acid clone showing sequence homology with genes coding for the eukaryotic elongation factor 1 gamma (EF-1 gamma). The clone encodes an open reading frame of 404 amino acids corresponding to a deduced molecular mass of 46.2 kDa. D...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Cañavate C,el Bali M,Montoya Y,Barker DC,Alvar J

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Despite the widespread use of multidrug therapy, leprosy remains an important public health concern in many regions. Detection is generally limited to clinical exam. METHODS:As a two-tiered active case finding strategy, we used the LID-1 (leprosy IDRI diagnostic-1), and PADL (protein advances for the diagno...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： de Souza MM,Netto EM,Nakatani M,Duthie MS

更新日期：2014-08-01 00:00:00

abstract：:A recently described simple kit for isolating African trypanosomes in vitro (KIVI) was tested further with blood samples from man and other animals in Côte d'Ivoire and République du Congo. A high rate of success was achieved, with positive cultures being found 5-36 d after inoculation. The method was also of value in...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Truc P,Aerts D,McNamara JJ,Claes Y,Allingham R,Le Ray D,Godfrey DG

更新日期：1992-11-01 00:00:00

abstract：:Three strains of Trypanosoma cruzi, used previously as prototypes for a classification based on the host-parasite relationships, as well as several stocks isolated from different geographical areas in Brazil, were submitted to isoenzymic analysis. Their isoenzyme patterns revealed a clear correlation with the biologic...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Andrade V,Brodskyn C,Andrade SG

更新日期：1983-01-01 00:00:00

abstract：:Four cases manifesting features characteristic of epidemic dropsy following body massage with contaminated mustard oil are reported. A transcutaneous route of absorption for the toxin (sanguinarine) resulting in epidemic dropsy has not been documented previously in man. Oil used for body massage was found to be adulte...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sood NN,Sachdev MS,Mohan M,Gupta SK,Sachdev HP

更新日期：1985-01-01 00:00:00

abstract：:The natural host of Plasmodium knowlesi is the kra monkey, Macaca fascicularis, but this parasite, initially mistaken for P. malariae, is now infecting humans in some areas of Southeast Asia. Here we present data from experiments performed in the 1970s in which sera from a few naive M. fascicularis, taken in the cours...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Butcher GA,Mitchell GH,Cohen S

更新日期：2010-01-01 00:00:00

abstract：:A man bitten by a large coral snake (Micrurus lemniscatus helleri) in the Amazon basin of Ecuador developed persistent excruciating pain in the bitten arm. On admission to hospital less than 30 min later, he had a polymorphonuclear leucocytosis, thrombocytopenia and mildly prolonged prothrombin time/partial thrombopla...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Manock SR,Suarez G,Graham D,Avila-Aguero ML,Warrell DA

更新日期：2008-11-01 00:00:00

abstract：:Mefloquine is an antimalarial drug with a 3-week elimination half-life, which has led to concerns that toxic accumulation may occur during weekly administration for long-term malaria chemoprophylaxis. Despite the endorsement of weekly mefloquine by the World Health Organization and the United States Centers for Diseas...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pennie RA,Koren G,Crevoisier C

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:The state of Rio de Janeiro has been important since 1986 as a portal for the introduction of dengue virus (DENV) into Brazil and dissemination of the virus throughout the country. This study describes an active surveillance of DENV in the state of Rio de Janeiro from 2004 to 2008. METHOD:A total of 14 408 ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Macedo GA,de Araújo JM,Schatzmayr HG,Costa FA,de Filippis AM,Santos FB,Nogueira RM

更新日期：2013-03-01 00:00:00

abstract：:The importance of enterotoxigenic Escherichia coli (ETEC) as a cause of diarrhoea in eastern Indonesia was investigated in 74 children during the dry season in Ujung Pandang. Six of the children less than five years old with diarrhoea were infected with ETEC. One child was infected with tetracycline-resistant bacteria...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Maidin MA

更新日期：1983-01-01 00:00:00

abstract：:We report the successful treatment of envenoming by the Gaboon viper (Bitis gabonica) and include results of in vitro investigations of the haemostatic properties of the whole venom. The patient was admitted to casualty soon after the bite with chest tightness, dizziness, nausea and swelling at the site of the bite an...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： McNally T,Conway GS,Jackson L,Theakston RD,Marsh NA,Warrell DA,Young L,Mackie IJ,Machin SJ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Immunoepidemiologic studies have shown a relationship between IgE and IgG4 antibodies with age and with resistance and susceptibility to infection. It is believed that the IgE and IgG4 responses to soluble egg antigen (SEA) can be used for serological analysis of infection and post-treatment status. This stu...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Matoso LF,Oliveira-Prado R,Abreu MN,Fujiwara RT,Loverde PT,Kloos H,Gazzinelli A,Correa-Oliveira R

更新日期：2013-12-01 00:00:00

abstract：:We performed pulsed-field gel electrophoresis (XbaI) on 114 bloodstream isolates of Salmonella enterica serotype Paratyphi A and S. enterica serotype Typhi collected from febrile patients in Kathmandu, Nepal. Of the 56 S. Paratyphi A isolates, 51 (91%) were indistinguishable, which suggests the emergence of a single c...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Woods CW,Murdoch DR,Zimmerman MD,Glover WA,Basnyat B,Wolf L,Belbase RH,Reller LB

更新日期：2006-11-01 00:00:00

abstract：:The leishmanin skin test was used in four different areas of the Italian Adriatic coast (Emilia Romagna, Marche, San Marino and Abruzzi), old endemic areas for cutaneous leishmaniasis. The test was found to be postitive in 80% of past infections, the 20% negative reactions being found in those who had been infected 20...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pampiglione S,Manson-Bahr PE,La Placa M,Borgatti MA,Micheloni F

更新日期：1976-01-01 00:00:00

abstract：:The effect of levamisole hydrochloride and mebendazole on Angiostrongylus malaysiensis infection in albino rats was studied. Animals at different stages of infection were treated with various oral doses of levamisole and mebendazole with the aim of finding an effective treatment regime. Levamisole was most effective f...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ambu S,Kwa BH,Mak JW

更新日期：1982-01-01 00:00:00

abstract：:Tuberculosis (TB) of the breast is a very rare pathology. The clinical presentations of this disease are manifold, often mimicking carcinoma of the breast. We conducted a retrospective analysis of 20 women with TB of the breast receiving care at the mastology clinic at Getúlio Vargas Hospital, PI, Brazil, between 1994...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： da Silva BB,Lopes-Costa PV,Pires CG,Pereira-Filho JD,dos Santos AR

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Leptospirosis is a zoonotic disease known to have wide-ranging clinical manifestations. Despite a number of published case series, culture-confirmed series are few and there is a paucity of data on Jarisch-Herxheimer reaction (JHR) associated with treatment of leptospirosis. Our objective was to describe the...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Tsuha S,Taniguchi T,Shiiki S,Narita M,Leung DT

更新日期：2016-09-01 00:00:00

abstract：:Difluoromethylornithine (DFMO), a specific, irreversible inhibitor of polyamine biosynthesis shown to be curative in animal models inoculated with various Trypanosoma spp., was evaluated in the Southern Sudan in a preliminary open clinical field trial in patients infected with Trypanosoma brucei gambiense. 20 patients...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Van Nieuwenhove S,Schechter PJ,Declercq J,Boné G,Burke J,Sjoerdsma A

更新日期：1985-01-01 00:00:00

abstract：:Quinine (n = 246) was used to treat uncomplicated Plasmodium falciparum and chloroquine (n = 130) was used to treat P. vivax, in a total of 376 episodes of malaria in the first trimester of pregnancy, in 300 Karen women (Thailand, 1995-2000). Parasites were still present on day 6 or 7 in 4.7% (11/234) of episodes trea...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： McGready R,Thwai KL,Cho T,Samuel,Looareesuwan S,White NJ,Nosten F

更新日期：2002-03-01 00:00:00

abstract：:A range of animal models of Burkholderia pseudomallei infection have been reported, and the host species differ widely both in their susceptibility to infection and in the pathogenesis of disease. In mice, and depending on the route of infection, dose, and mouse strain, the disease can range from a chronic, and in som...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Titball RW,Russell P,Cuccui J,Easton A,Haque A,Atkins T,Sarkar-Tyson M,Harley V,Wren B,Bancroft GJ

更新日期：2008-12-01 00:00:00

abstract：:A possible association between nutritional status and Schistosoma mansoni infection or morbidity was investigated by comparing anthropometric indices among 362 children from 3 primary schools in Machakos District, Kenya. Matithini was a prosperous school in an area (Kangundo) of moderate intensity of schistosome infec...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Corbett EL,Butterworth AE,Fulford AJ,Ouma JH,Sturrock RF

更新日期：1992-05-01 00:00:00

abstract：:Study of the effects of malaria chemoprophylaxis given during pregnancy on birthweight and investigation of the influence of birthweight on child survival suggest that, in a rural area of The Gambia, chemoprophylaxis given during pregnancy might reduce infant mortality by about one-fifth in the children of primigravid...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Greenwood AM,Armstrong JR,Byass P,Snow RW,Greenwood BM

更新日期：1992-09-01 00:00:00

abstract：Background:After new analysis, Sanofi Pasteur now recommends their dengue vaccine (Dengvaxia) should only be given to individuals previously infected with dengue and the World Health Organization's recommendations regarding its use are currently being revised. As a result, the potential costs of performing large-scale ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Turner HC,Wills BA,Rahman M,Quoc Cuong H,Thwaites GE,Boni MF,Clapham HE

更新日期：2018-08-01 00:00:00

abstract：:We report two patients who presented with a long-lasting febrile illness associated with pancytopenia. Both of them had evidence of hypercellular marrow with haemophagocytosis. They were confirmed as having rickettsial infections by serology and had a rapid haematological recovery with anti-rickettsial antibiotics. We...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Premaratna R,Williams HS,Chandrasena TG,Rajapakse RP,Kularatna SA,de Silva HJ

更新日期：2009-09-01 00:00:00

abstract：:Tungiasis (jigger) is endemic in many impoverished communities in many parts of Brazil. Forty-seven individuals entering an endemic area were followed up for a period of six weeks and regularly examined for the presence of newly embedded sand fleas. At the end of the third week, the attack rate of Tunga penetrans infe...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Heukelbach J,Franck S,Feldmeier H

更新日期：2004-07-01 00:00:00

abstract：:Plasmodium falciparum in Thailand is highly resistant to available antimalarial drugs. Artemether, a derivative of artemisinin, is a promising compound currently used to cope with this situation but the course of treatment has to be at least 5 d. An effective short treatment course of this drug is possible when used i...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Karbwang J,Na-Bangchang K,Thanavibul A,Ditta-in M,Harinasuta T

更新日期：1995-05-01 00:00:00

abstract：:A retrospective analysis of the medical records of 1970 patients admitted to the intensive care unit of the Clinical Research Centre in Dhaka, Bangladesh was made, to identify various complications and outcome. All patients were admitted with a history of diarrhoea. Children under 5 years old comprised 90% of these pa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mitra AK,Khan MR,Alam AN

更新日期：1991-09-01 00:00:00

abstract：:We conducted experiments in vitro to assess the effect of artemether in combination with haemin on adult Schistosoma japonicum, S. mansoni and S. haematobium. When schistosomes were maintained in a medium containing artemether at concentrations of 20 micrograms/mL or less for 72 h, no apparent effect on the schistosom...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Xiao S,Chollet J,Utzinger J,Matile H,Mei J,Tanner M

更新日期：2001-01-01 00:00:00

abstract：:Subclinical mastitis, defined as raised milk sodium/potassium (Na/K) ratio is common and associated with poor infant growth and increased mother-to-child HIV transmission. In 1996-97, we conducted a randomized controlled trial of multiple micronutrient supplementation, at recommended daily allowance levels, from 22 to...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Gomo E,Filteau SM,Tomkins AM,Ndhlovu P,Michaelsen KF,Friis H

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:The objective of study was to estimate the incremental cost-effectiveness ratio (ICER) of diagnostic options for visceral leishmaniasis (VL) in Brazil. METHODS:Six diagnostic tests were considered: IT LEISH, Kalazar Detect, DAT-LPC (DAT made in the Laboratório de Pesquisas Clínicas), IFAT, PCR and direct ex...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Machado de Assis TS,Azeredo-da-Silva AL,Werneck GL,Rabello A

更新日期：2016-08-01 00:00:00