Studies on the experimental chemotherapy of Angiostrongylus malaysiensis infection in rats with mebendazole and levamisole.

Abstract:

:The effect of levamisole hydrochloride and mebendazole on Angiostrongylus malaysiensis infection in albino rats was studied. Animals at different stages of infection were treated with various oral doses of levamisole and mebendazole with the aim of finding an effective treatment regime. Levamisole was most effective for treating rats seven days after infection but its efficacy dropped as infection progressed. Mebendazole given at a dose of 1 mg/kg for five days was more effective against early larval stages (97.39% efficacy). At 5 mg/kg for five days mebendazole was more effective than levamisole against all stages of the infection.

authors

Ambu S,Kwa BH,Mak JW

doi

10.1016/0035-9203(82)90135-3

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

458-62

issue

4

eissn

0035-9203

issn

1878-3503

journal_volume

76

pub_type

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