Abstract：
:Tuberculosis (TB) of the breast is a very rare pathology. The clinical presentations of this disease are manifold, often mimicking carcinoma of the breast. We conducted a retrospective analysis of 20 women with TB of the breast receiving care at the mastology clinic at Getúlio Vargas Hospital, PI, Brazil, between 1994 and 2007. The clinical presentation of the disease, the diagnosis and the response to specific treatment were analyzed. Most of the patients were of reproductive age, with the disease affecting the right breast in eleven patients (55%) and the left breast in nine patients (45%). Palpable nodules were present in five patients (25%) and fistulae in 15 (75%). The mean time between onset of symptoms and diagnosis was 7.7 months (range 3-12 months). Skin testing with purified protein derivative of tuberculin was strongly reactive in all patients, six (30%) of whom were breastfeeding. Diagnosis was confirmed by histopathology and all patients were satisfactorily treated with a combination of rifampicin, isoniazid and pyrazinamide. In the present study, TB of the breast presented predominantly as breast abscesses and fistulae and responded satisfactorily to treatment with anti-TB drugs.
journal_name
Trans R Soc Trop Med Hygauthors
da Silva BB,Lopes-Costa PV,Pires CG,Pereira-Filho JD,dos Santos ARdoi
10.1016/j.trstmh.2009.02.005subject
Has Abstractpub_date
2009-06-01 00:00:00pages
559-63issue
6eissn
0035-9203issn
1878-3503pii
S0035-9203(09)00047-9journal_volume
103pub_type
杂志文章,评审abstract：:Active community and self-reporting surveillance techniques have been used to describe the dynamics of febrile illness and associated malaria infection in children aged 2 to 15 years from a rural area of Madang Province, Papua New Guinea (PNG). Both history of fever and fever in association with parasitaemia appeared ...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(94)90292-5
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:Schistosoma haematobium infection is a major public health problem in most of Africa and the Middle East and praziquantel remains the only drug used for schistosomiasis control, therefore emergence of drug resistance is unavoidable. The antimalarial artemisinin-naphthoquine phosphate combination (co-ArNp) wa...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1093/trstmh/try144
更新日期：2019-06-01 00:00:00
abstract：:Severe anaemia in pregnancy is an important preventable cause of maternal and perinatal morbidity and mortality. Different methods of screening for severe anaemia in pregnancy were evaluated in a 2-phased study conducted in Kilifi, Kenya. In phase 1 (in 1994/95), pallor testing was evaluated alone and in addition to r...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章,多中心研究
doi：10.1016/s0035-9203(01)90227-5
更新日期：2001-05-01 00:00:00
abstract：:A meta-analysis of rapid (
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.trstmh.2005.10.018
更新日期：2006-08-01 00:00:00
abstract：:The new OptiMAL-IT(R) rapid diagnostic test for malaria was evaluated in 271 patients in Thailand with uncomplicated malaria between June and July 2002. The sensitivity and specificity for the diagnosis of Plasmodium falciparum parasites were 88% and 92%, respectively. For species other than P. falciparum, the sensiti...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(03)80100-1
更新日期：2003-11-01 00:00:00
abstract：:Isoenzyme profiles of 28 stocks of Leishmania aethiopica were compared with those of reference strains of L. aethiopica, L. tropica and L. major using starch-gel electrophoresis of 13 enzymes (GPI, GD, ES, PGM, PEPD, NH, ASAT, ALAT, PK, MPI, 6PGD, SOD, MDH). 13 zymodemes were seen. L. aethiopica showed some infraspeci...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(86)90318-4
更新日期：1986-01-01 00:00:00
abstract：:Immune reactions to the surface of microfilariae (mff) of Wuchereria bancrofti were investigated among persons living in an endemic filariasis area of Tanzania. The sera from a proportion of mff-negative persons contained antibodies to the microfilarial sheath, and a clear correlation was seen between presence of anti...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(85)90137-3
更新日期：1985-01-01 00:00:00
abstract：:There is a need for a specific, sensitive, and practical diagnostic test to monitor onchocerciasis elimination campaigns. In April 2001, an enzyme-linked immunosorbent assay (ELISA) using 3 recombinant antigens and a rapid-format antibody card test (immunochromatographic test; ICT) using an individual antigen were com...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(03)80018-4
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:We aimed to estimate and compare the ability of clinical tools for dengue diagnosis in a pediatric population. METHODS:We prospectively evaluated episodes of acute febrile syndrome identified during the follow-up of a population-based cohort of children and adolescents residing in a dengue endemic city. We ...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1093/trstmh/try135
更新日期：2019-04-01 00:00:00
abstract：:A retrospective cohort study of mortality rates and potential predictors of death was conducted in public-sector patients initiating highly active antiretroviral therapy (HAART) between October 2005 and September 2007 in a rural, under-resourced region of South Africa. The aims were to determine the relative contribut...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2008.10.001
更新日期：2009-06-01 00:00:00
abstract：:One hundred and eighteen patients with acute falciparum malaria were randomized into treatment with either intramuscular or oral sulfadoxine-pyrimethamine (Fansidar, Roche) and the results were compared with those from 68 patients treated in parallel with chloroquine. Parasitological cure rate was 97% with oral sulfad...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0035-9203(90)90131-w
更新日期：1990-09-01 00:00:00
abstract：:Quinine (n = 246) was used to treat uncomplicated Plasmodium falciparum and chloroquine (n = 130) was used to treat P. vivax, in a total of 376 episodes of malaria in the first trimester of pregnancy, in 300 Karen women (Thailand, 1995-2000). Parasites were still present on day 6 or 7 in 4.7% (11/234) of episodes trea...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(02)90297-x
更新日期：2002-03-01 00:00:00
abstract：:A study was carried out to assess the patterns of resistance and occurrence of DHFR/DHPS genotypes of Plasmodium falciparum prior to the adoption of sulfadoxine-pyrimethamine (SP) as first-line treatment for uncomplicated malaria in Tanzania. Children under five years (n = 117) with clinical, uncomplicated malaria wer...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.trstmh.2003.10.010
更新日期：2004-06-01 00:00:00
abstract：:A new microplate assay for the determination of activity in vitro against Giardia intestinalis has been developed in which viability is measured by soluble formazan production from a tetrazolium reagent. Metabolic reduction of the latter gives rise to a coloured product which may be determined directly by optical dens...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(92)90093-r
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:Large numbers of tuberculosis (TB) patients seek care from private for-profit providers. This study aimed to assess and compare TB control activities in the private for-profit and public sectors in Kenya between 2013 and 2017. METHODS:We conducted a retrospective cross-sectional study using routinely collec...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1093/trstmh/trz062
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Leptospirosis is a zoonotic disease known to have wide-ranging clinical manifestations. Despite a number of published case series, culture-confirmed series are few and there is a paucity of data on Jarisch-Herxheimer reaction (JHR) associated with treatment of leptospirosis. Our objective was to describe the...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1093/trstmh/trw061
更新日期：2016-09-01 00:00:00
abstract：:This paper reports on adverse reactions following a 12-day course of 6 mg/kg diethylcarbamazine (DEC) therapy in brugian filariasis patients in Indonesia. Microfilaria-positive individuals (n = 26), 'endemic normals' (n = 12) and elephantiasis patients (n = 17) were included in the study. Fever, headache and body ache...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(99)90194-3
更新日期：1999-01-01 00:00:00
abstract：:The possible depression of cell-mediated immunity by long-term Brugia malayi infection in jirds (Meriones unguiculatus) was investigated. Different groups of infected jirds were sensitized with dinitrofluorobenzene, sheep red blood cells, Dirofilaria immitis adult antigens and B. malayi adult antigens. The 24-hour del...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(80)90070-x
更新日期：1980-01-01 00:00:00
abstract：:Helicobacter pylori is strongly associated with peptic ulcer and gastric cancer and may be the most common human bacterial infection. The epidemiology of H. pylori has been poorly studied in Africa, where its relevance to disease has not been fully appreciated. Following a cross-sectional study design, H. pylori infec...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2007.05.003
更新日期：2007-09-01 00:00:00
abstract：:The leishmanin skin test was used in four different areas of the Italian Adriatic coast (Emilia Romagna, Marche, San Marino and Abruzzi), old endemic areas for cutaneous leishmaniasis. The test was found to be postitive in 80% of past infections, the 20% negative reactions being found in those who had been infected 20...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(76)90009-2
更新日期：1976-01-01 00:00:00
abstract：:Mice immunized with purified antigen preparations produced in Escherichia coli and containing the glutathione S-transferase (GST) isoenzyme of Schistosoma japonicum (Sj26) can be partially resistant to infection with this parasite. Maximum resistance was approximately 50% and no protection was obtained in BALB/c mice,...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(88)90027-2
更新日期：1988-01-01 00:00:00
abstract：:ELISA AND IFAT have been applied to the sero-diagnosis of cutaneous and visceral leishmaniasis and the levels of leishmanial antibody detected by Leishmania donovani antigens in both tests have been compared. From the results it appears that ELISA is a little more sensitive than IFAT, but IFAT seems to be more specifi...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(79)90084-1
更新日期：1979-01-01 00:00:00
abstract：:Three strains of Trypanosoma cruzi, used previously as prototypes for a classification based on the host-parasite relationships, as well as several stocks isolated from different geographical areas in Brazil, were submitted to isoenzymic analysis. Their isoenzyme patterns revealed a clear correlation with the biologic...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(83)90292-4
更新日期：1983-01-01 00:00:00
abstract：:A study was undertaken to assess the role of cockroaches as potential carriers of human intestinal parasites in Addis Ababa and Ziway, Ethiopia. A total of 6480 cockroaches were trapped from the two localities from October 2006 to March 2007. All the cockroaches trapped in Addis Ababa (n=2240) and almost 50% (2100/424...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2008.05.009
更新日期：2008-11-01 00:00:00
abstract：:A cohort of 48 Gambian children was protected against malaria by fortnightly administration of Maloprim (pyrimethamine and dapsone) for 2 years between their 3 and 5 birthdays. A matched cohort of 47 children received placebo. During the year following the termination of prophylaxis there was no increase in the freque...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 临床试验,杂志文章
doi：10.1016/0035-9203(88)90263-5
更新日期：1988-01-01 00:00:00
abstract：:Infantile visceral leishmaniasis (VL) was first reported from north Pakistan over 3 decades age in the remote valleys of the western Himalayas. These foci were reported as being completely devoid of domestic dogs. The later emergence of sporadic cases of infantile VL in the sub-Himalayan region of the country, where d...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(95)90409-3
更新日期：1995-11-01 00:00:00
abstract：:Manifestations of cysticercosis in 11 children (mean age 9.5 years) are presented. Features of raised intracranial pressure dominated the clinical picture (10 cases), followed by seizures (7 cases). Subretinal cysts occurred in three children. Focal signs were infrequent and often not attributable to anatomical lesion...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(87)90138-6
更新日期：1987-01-01 00:00:00
abstract：:In helminthology, the mean number of eggs per gram of faeces (EPG) is a commonly used indicator for the severity of the infection in a population. The example presented here shows that, in my opinion, mean EPG (either calculated as arithmetic or geometric means) is not the best way to evaluate the impact of control me...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2007.04.008
更新日期：2007-08-01 00:00:00
abstract：:Lymphatic filariasis (LF) caused by Wuchereria bancrofti is widely prevalent in tropical and subtropical countries. Night blood film examination is most commonly used for diagnosis of filariasis but is cumbersome and labour intensive. In order to develop an indirect ELISA-based immunodiagnostic test, the importance of...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2010.02.007
更新日期：2010-08-01 00:00:00
abstract：:The genetic polymorphism of Leishmania (Viannia) braziliensis detected in cases of mucosal leishmaniasis (ML) from HIV-infected and non HIV-infected patients was evaluated. Nine samples from three HIV-infected patients and five samples from five non HIV-infected patients were analysed by polymerase chain reaction (PCR...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2012.07.007
更新日期：2012-11-01 00:00:00
