Filarial selenium glutathione peroxidase: a probable immunodiagnostic marker for lymphatic filariasis.

abstract：BACKGROUND:Artemisinin-based combination therapies (ACTs) have proven highly effective in reducing malaria morbidity in sub-Saharan Africa. Artemether-lumefantrine (AL) was introduced in 2005 as a first-line ACT for the treatment of uncomplicated malaria in Rwanda. Monitoring the therapeutic efficacy of ACTs is necessa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Uwimana A,Penkunas MJ,Nisingizwe MP,Warsame M,Umulisa N,Uyizeye D,Musanabaganwa C,Munyaneza T,Ntagwabira E,Hakizimana D,Muvunyi CM,Kayobotsi C,Kabera M,Murindahabi M,Mbituyumuremyi A

更新日期：2019-06-01 00:00:00

abstract：:Accurate identification of Leishmania species is important for monitoring clinical outcome, adequately targeting treatment, and evaluation of epidemiological risk in tegumentary leishmaniasis. This is especially the case in regions where several species coexist and for travel medicine where the geographical source of ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Victoir K,De Doncker S,Cabrera L,Alvarez E,Arevalo J,Llanos-Cuentas A,Le Ray D,Dujardin JC

更新日期：2003-01-01 00:00:00

abstract：:Mice immunized with purified antigen preparations produced in Escherichia coli and containing the glutathione S-transferase (GST) isoenzyme of Schistosoma japonicum (Sj26) can be partially resistant to infection with this parasite. Maximum resistance was approximately 50% and no protection was obtained in BALB/c mice,...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mitchell GF,Garcia EG,Davern KM,Tiu WU,Smith DB

更新日期：1988-01-01 00:00:00

abstract：:Nutritional deficiency and malaria are 2 major causes of anaemia during pregnancy in tropical areas. The relationship between anaemia, its treatment with iron and folate, and malaria was studied in a prospective cohort of 2112 pregnant Karen women on the north-western border of Thailand between 1993 and 1997. The deve...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Nacher M,McGready R,Stepniewska K,Cho T,Looareesuwan S,White NJ,Nosten F

更新日期：2003-05-01 00:00:00

abstract：:Lysophospholipid analogues (LPAs) comprise a class of metabolically stable compounds that have been developed as anticancer agents for over two decades, but which have also potent and selective antiparasitic activity, particularly against trypanosomatid parasites such as Leishmania and Trypanosoma cruzi, both in vitro...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Urbina JA

更新日期：2006-12-01 00:00:00

abstract：:Manifestations of cysticercosis in 11 children (mean age 9.5 years) are presented. Features of raised intracranial pressure dominated the clinical picture (10 cases), followed by seizures (7 cases). Subretinal cysts occurred in three children. Focal signs were infrequent and often not attributable to anatomical lesion...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kalra V,Paul VK,Marwah RK,Kochhar GS,Bhargava S

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Dengue fever (DF) is an urban vector-borne disease transmitted by Aedes aegypti and Aedes albopictus. Both species deposit their eggs in favorable breeding sites either in natural or artificial containers. An understanding of their habitat characteristics is crucial in curbing DF outbreaks METHODS:A search ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Dom NC,Faiz Madzlan M,Nadira Yusoff SN,Hassan Ahmad A,Ismail R,Nazrina Camalxaman S

更新日期：2016-04-01 00:00:00

abstract：:WHO recommends that anthelmintic treatment be included in strategies to improve maternal nutrition in areas where hookworms are endemic and anaemia is prevalent. At present, few countries have adopted this recommendation, partly owing to the lack of data to support the adverse effects of hookworms on maternal health. ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Torlesse H,Hodges M

更新日期：2001-03-01 00:00:00

abstract：:The commercial dot-blot enzyme-linked immunosorbent assay Dip-S-Ticks dipstick test was compared with the indirect immunoperoxidase (IIP) and Weil-Felix (WF) tests for the diagnosis of scrub typhus, using the indirect immunofluorescent antibody test (IFA) as the reference standard. With a panel of 117 positive and 75 ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pradutkanchana J,Silpapojakul K,Paxton H,Pradutkanchana S,Kelly DJ,Strickman D

更新日期：1997-07-01 00:00:00

abstract：:The identification of early markers that predict the response to anti-tuberculosis treatment would facilitate evaluation of new drugs and improve patient management. This study aimed to determine whether selected acute phase proteins and micronutrients measured at the time of diagnosis and during the first weeks of tr...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Almeida ML,Barbieri MA,Gurgel RQ,Abdurrahman ST,Baba UA,Hart CA,Shenkin A,Silva AM,de Souza L,Cuevas LE

更新日期：2009-06-01 00:00:00

abstract：:The spread of chloroquine-resistant malaria has led to a resurgence of quinine in clinical use. One of the well-known side effects of quinine, reversible hearing loss, is closely related to the plasma concentration. We suggest that this hearing effect could be used as an aid in therapy control when quinine drug assay ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Karlsson KK,Hellgren U,Alván G,Rombo L

更新日期：1990-11-01 00:00:00

abstract：:Young African children with severe malaria are given quinine using a regimen designed for Thai adults. We measured quinine in the blood, plasma and plasma water of young children in Kenya after rapid intravenous and intramuscular dosing, and calculated the therapeutic range of unbound quinine. The peak plasma quinine ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Winstanley P,Newton C,Watkins W,Mberu E,Ward S,Warn P,Mwangi I,Waruiru C,Pasvol G,Warrell D

更新日期：1993-03-01 00:00:00

abstract：:Bone marrow cultures in 15 Plasmodium falciparum patients were studied both during and after parasitaemia. Abnormalities were observed only in the group during parasitaemia. These abnormalities included: (1) decreased normoblastic number and cellular iron incorporation in all cases; (2) premature death of normoblasts ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Srichaikul T,Siriasawakul T,Poshyachinda M

更新日期：1976-01-01 00:00:00

abstract：:Ciprofloxacin (20 mg/kg/d) or ofloxacin (12 mg/kg/d) given for a median of 15 weeks (range 12-40) were used for maintenance treatment of 57 adult patients with melioidosis. The median duration of follow-up in the 45 patients who complied with treatment and were followed for at least 6 months was 28 months (range 6-65)...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Chaowagul W,Suputtamongkul Y,Smith MD,White NJ

更新日期：1997-09-01 00:00:00

abstract：:Peripheral blood mononuclear cells (PBMC) of patients with Indian visceral leishmaniasis (VL) suppressed the natural killer cell (NK) activity of normal human PBMC in vitro in a dose-dependent manner. Adherent monocytes, but not the non-adherent lymphocytes of VL patients suppressed NK activity through soluble mediato...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Chakrabarti G,Basu A,Manna PP,Bhattacharya S,Sen S,Bandyopadhyay S

更新日期：1996-09-01 00:00:00

abstract：:The COVID-19 pandemic has exposed health system weaknesses of economically wealthy countries with advanced technologies. COVID-19 is now moving fast across Africa where small outbreaks have been reported so far. There is a concern that with the winter transmission will grow rapidly. Despite efforts of African Governme...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Vilakati PN,Villa S,Alagna R,Khumalo B,Tshuma S,Quaresima V,Nieman NR,Cirillo DM,Raviglione MC

更新日期：2020-10-05 00:00:00

abstract：:The safety and tolerability of primaquine (PQ) administered as a short higher-dose (30mg twice daily for 7 days) regimen in 203 Australian Defence Force personnel was evaluated in an open-label presumptive anti-relapse therapy study. No clinically significant differences were measured in the subjects' haematological a...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ebringer A,Heathcote G,Baker J,Waller M,Shanks GD,Edstein MD

更新日期：2011-10-01 00:00:00

abstract：:The clinical occurrence of Pneumocystis carinii and Mycobacterium tuberculosis was investigated in patients infected with human immunodeficiency virus (HIV) who had clinical pneumonia of unknown aetiology in Lusaka, Zambia. The results were compared with a similar group of patients in Stockholm, Sweden. Induced sputum...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Elvin KM,Lumbwe CM,Luo NP,Björkman A,Källenius G,Linder E

更新日期：1989-07-01 00:00:00

abstract：:A possible association between nutritional status and Schistosoma mansoni infection or morbidity was investigated by comparing anthropometric indices among 362 children from 3 primary schools in Machakos District, Kenya. Matithini was a prosperous school in an area (Kangundo) of moderate intensity of schistosome infec...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Corbett EL,Butterworth AE,Fulford AJ,Ouma JH,Sturrock RF

更新日期：1992-05-01 00:00:00

abstract：:A prospective seroepidemiological survey for latent congenital toxoplasmosis was carried out among 4,136 women and 3,787 of their offspring in and around Montreal. The indirect immunofluorescent antibody test was used to titrate specific IgG and IgM antibodies and results were standardized in international units. The ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Viens P,Auger P,Villeneuve R,Stefanescu-Soare I

更新日期：1977-01-01 00:00:00

abstract：:The first case of Sarcocystis infection is reported from West Malaysia. A cyst was seen as an incidental finding in a biopsy specimen from the larynx of the patient. The cyst and the cystozoites were of the small size with no evidence of cytophaneres or compartments. ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kutty MK,Dissanaike AS

更新日期：1975-01-01 00:00:00

abstract：:Cholera remains a grave public health problem in Africa. It is endemic with seasonal variations around the central African Great Lakes. Along the coasts, it occurs mostly in rapidly expanding epidemics, with intercalated 3-5 year lull-periods. Case-fatality ratios remain high at 2–5% against the global declining trend...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mengel MA

更新日期：2014-07-01 00:00:00

abstract：:In helminthology, the mean number of eggs per gram of faeces (EPG) is a commonly used indicator for the severity of the infection in a population. The example presented here shows that, in my opinion, mean EPG (either calculated as arithmetic or geometric means) is not the best way to evaluate the impact of control me...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Montresor A

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:We aimed to characterise the genetic determinants and context of two meropenem-resistant clinical isolates of Acinetobacter baumannii isolated from children hospitalised with bloodstream infections in Dar es Salaam, Tanzania. METHODS:Antimicrobial susceptibility was determined by disc diffusion E-test and b...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Moyo SJ,Manyahi J,Hubbard ATM,Byrne RL,Masoud NS,Aboud S,Manji K,Blomberg B,Langeland N,Roberts AP

更新日期：2021-01-27 00:00:00

abstract：:Community treatment with ivermectin was implemented in Opoa, French Polynesia from April 1991 to October 1993. All consenting inhabitants aged 3 years or more were treated with twice-yearly single doses of ivermectin, pregnant women excepted. A dosage of 100 microgram/kg was used for the 3 first treatments and then ab...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Nguyen NL,Moulia-Pelat JP,Cartel JL

更新日期：1996-11-01 00:00:00

abstract：:Yellow fever (YF), an arthropod-borne viral disease, occurs in regions of tropical America and Africa. Sylvatic YF is endemic in the north and west of Brazil. Urban YF, on the other hand, has not been reported in the country since 1942. However, the widespread presence of the YF urban vector in Brazil has lead to conc...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Codeço CT,Luz PM,Struchiner CJ

更新日期：2004-12-01 00:00:00

abstract：:A survey at Richards Bay, the site of a new international harbour on the east coast of South Africa, revealed the presence of 11 anthropophilic mosquito species. These are discussed in relation to their known medical importance and to a complementary survey of arbovirus antibodies among residents of the area. Mansonia...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sharp BL,Appleton CC,Thompson DL,Meenehan G

更新日期：1987-01-01 00:00:00

abstract：:Fifty surgically confirmed cases of hydatid disease in Eastern Libya were investigated. Of these, 30 had cysts of the liver, five had extra-hepatic abdominal cysts and 15 had cysts in the chest, including the lungs. Ten cases of malignancy of the liver and five cases of malignancy of the lung were used as controls. Di...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Taguri S,Dar FK

更新日期：1978-01-01 00:00:00

abstract：:The direct agglutination test (DAT) has been assessed as a diagnostic procedure for visceral leishmaniasis. Fifty-six of 58 sera (96.5%) from confirmed cases of visceral leishmaniasis, whose bone marrow aspirates contained Leishmania donovani amastigotes, had agglutinating antibodies above the cut-off titre of 1:800. ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Singla N,Singh GS,Sundar S,Vinayak VK

更新日期：1993-05-01 00:00:00

abstract：:Between July 1989 and December 1990, 4504 new adult patients with tuberculosis were screened for antibodies to human immunodeficiency viruses (HIV) 1 and 2 in Abidjan's 2 tuberculosis treatment centres. The prevalence levels of HIV-1 and HIV-2 infections were 30.2% and 4.2% respectively, a further 9.3% of patients rea...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Gnaore E,Sassan-Morokro M,Kassim S,Ackah A,Yesso G,Adjorlolo G,Digbeu H,Coulibaly D,Coulibaly IM,Doorly R

更新日期：1993-01-01 00:00:00