Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration.

abstract：:The optimum treatment for louse-borne relapsing fever (LBRF) has not been fully established. Eliminating spirochetes is often associated with the potentially lethal Jarisch-Herxheimer reaction (JHR). The objective of this meta-analysis was to review the evidence supporting the use of antibiotics usually employed for t...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Guerrier G,Doherty T

更新日期：2011-09-01 00:00:00

abstract：:In order to help primary health care (PHC) workers in developing countries in the care of common skin diseases, an algorithm for the management of pyoderma, scabies, superficial mycoses, contact dermatitis and referral of early leprosy cases (based on the identification of diseases through the presence of objective ke...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mahé A,Faye O,N'Diaye HT,Ly F,Konaré H,Kéita S,Traoré AK,Hay R

更新日期：2005-01-01 00:00:00

abstract：:Mice immunized with purified antigen preparations produced in Escherichia coli and containing the glutathione S-transferase (GST) isoenzyme of Schistosoma japonicum (Sj26) can be partially resistant to infection with this parasite. Maximum resistance was approximately 50% and no protection was obtained in BALB/c mice,...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mitchell GF,Garcia EG,Davern KM,Tiu WU,Smith DB

更新日期：1988-01-01 00:00:00

abstract：:We describe here a method, potentially suitable for field applications, for semi-quantitative detection of Mycobacterium leprae antigens in skin scrapings, which are taken normally for smear microscopy. Thirty acid-fast bacilli-negative paucibacillary (PB) leprosy patients comprised the main study group; eight acid-fa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Chaturvedi V,Girdhar BK,Sengupta U,Sinha S

更新日期：2007-07-01 00:00:00

abstract：:Arboviruses are maintained and transmitted through an alternating biological cycle in arthropods and vertebrates, with largely incidental disease in humans and animals. As such, they provide excellent examples of One Health, as their health impact is inextricably linked to their vertebrate hosts, their arthropod vecto...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mackenzie JS,Lindsay MDA,Smith DW,Imrie A

更新日期：2017-06-01 00:00:00

abstract：:The influence of haptoglobin polymorphisms on severe malaria occurrence was assessed in 1183 individuals from The Gambia. No significant association was found between severe malaria and either haptoglobin genotypes or phenotypes. The advantages of using a deoxyribonucleic acid-based haptoglobin typing method are discu...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Aucan C,Walley AJ,Greenwood BM,Hill AV

更新日期：2002-05-01 00:00:00

abstract：:Both northern and southern Sudan are deploying artemisinin-based combinations against uncomplicated Plasmodium falciparum malaria (artesunate+sulfadoxine-pyrimethamine [AS+SP] in the north, artesunate+amodiaquine [AS+AQ] in the south). In 2003, we tested the efficacy of 3 day AS+SP and AS+AQ regimens in vivo in the is...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Hamour S,Melaku Y,Keus K,Wambugu J,Atkin S,Montgomery J,Ford N,Hook C,Checchi F

更新日期：2005-07-01 00:00:00

abstract：:The polymerase chain reaction was applied to capillary blood spots dried on filter paper from 20 parasitologically proved cases of visceral leishmaniasis (VL), 21 subclinical cases, and 11 healthy controls in a longitudinal study of anthroponotic VL in Baringo District, Kenya. Leishmania deoxyribonucleic acid (DNA) wa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Schaefer KU,Schoone GJ,Gachihi GS,Muller AS,Kager PA,Meredith SE

更新日期：1995-09-01 00:00:00

abstract：:A total of 1,197 wild animals from Pará State north Brazil, were examined for haematozoa. Trypanosoma cruzi-like parasites were found in 13 different species, and were particularly common in a variety of marsupials (Didelphidae), porcupines (Coendou spp.), armadillos (Dasypus novemcinctus) and coatimundis(Nasua nasua)...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Lainson R,Shaw JJ,Fraiha H,Miles MA,Draper CC

更新日期：1979-01-01 00:00:00

abstract：:Subclinical mastitis, defined as raised milk sodium/potassium (Na/K) ratio is common and associated with poor infant growth and increased mother-to-child HIV transmission. In 1996-97, we conducted a randomized controlled trial of multiple micronutrient supplementation, at recommended daily allowance levels, from 22 to...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Gomo E,Filteau SM,Tomkins AM,Ndhlovu P,Michaelsen KF,Friis H

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Aedes aegypti rapid larval surveys are mandatory in Brazil. Here, we retrospectively examined whether the house index estimated by larval surveys served as a useful tool in anticipating epidemics within Brazilian municipalities from 2009-2015. METHODS:We used correlation indices and classification analysis ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Enslen AW,Lima Neto AS,Castro MC

更新日期：2020-07-01 00:00:00

abstract：:An estimated 129 million people are infected with urogenital schistosomiasis in sub-Saharan Africa. Current control recommendations endorse mass administration of praziquantel. Health education is an important component of effective schistosomiasis prevention and control, but there has been limited research on its eff...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Price A,Verma A,Welfare W

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Mumbai is a hot spot for drug-resistant TB, and private practitioners trained in AYUSH systems (Ayurveda, yoga, Unani, Siddha and homeopathy) are major healthcare providers. It is important to understand how AYUSH practitioners manage patients with TB or presumptive TB. METHODS:We conducted semi-structured ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： McDowell A,Pai M

更新日期：2016-03-01 00:00:00

abstract：:Thirty-eight patients with beri-beri (13 dry, 14 wet and 11 mixed type) were seen at the Royal Victoria Hospital, Banjul, The Gambia, in 1990-1991, with a peak in September-October (25 cases) during the latter half of the rainy season. They were all non-confined residents of urban areas. Overt risk factors were pregna...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Rolfe M,Walker RW,Samba KN,Cham K

更新日期：1993-01-01 00:00:00

abstract：:The incidence and progression of coagulation abnormalities were studied in 52 patients with acute falciparum malaria. The patients were prospectively divided into 3 groups; severe (parasitaemia greater than or equal to 5% or vital organ dysfunction), 12 patients; moderate (parasitaemia 1%- less than 5% without complic...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pukrittayakamee S,White NJ,Clemens R,Chittamas S,Karges HE,Desakorn V,Looareesuwan S,Bunnag D

更新日期：1989-11-01 00:00:00

abstract：:Four cases manifesting features characteristic of epidemic dropsy following body massage with contaminated mustard oil are reported. A transcutaneous route of absorption for the toxin (sanguinarine) resulting in epidemic dropsy has not been documented previously in man. Oil used for body massage was found to be adulte...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sood NN,Sachdev MS,Mohan M,Gupta SK,Sachdev HP

更新日期：1985-01-01 00:00:00

abstract：Background:Chronic hepatitis B infection affects 240 million people, with the highest prevalence in Africa and Asia, and results in 700 000 deaths annually. Access to diagnostics, particularly for hepatitis B virus viral load quantification (HBV DNA), is a major barrier to treatment. We aimed to test World Health Organ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Laing N,Tufton H,Ochola E,P'Kingston OG,Maini MK,Easom N

更新日期：2019-01-01 00:00:00

abstract：:Difluoromethylornithine (DFMO), a specific, irreversible inhibitor of polyamine biosynthesis shown to be curative in animal models inoculated with various Trypanosoma spp., was evaluated in the Southern Sudan in a preliminary open clinical field trial in patients infected with Trypanosoma brucei gambiense. 20 patients...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Van Nieuwenhove S,Schechter PJ,Declercq J,Boné G,Burke J,Sjoerdsma A

更新日期：1985-01-01 00:00:00

abstract：:A population-based study of the clinical, laboratory and ultrasonographic findings in patients suffering from mild or moderate opisthorchiasis in Prachinburi province, Thailand was conducted in 1990-1992. The effectiveness of treatment with praziquantel at 40 mg/kg body weight was evaluated. After treatment, a long-la...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pungpak S,Chalermrut K,Harinasuta T,Viravan C,Schelp PF,Hempfling A,Schlattmann P,Bunnag D

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Early identification of patients at risk of severe dengue disease (DD) is critical to guide its management. We evaluated whether the atypical lymphocyte count (ALC), generated from the Sysmex automated full blood count analyzer, is predictive of severe thrombocytopenia secondary to Dengue infection. METHODS...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Abeysuriya V,Choong CSH,Thilakawardana BU,de Mel P,Shalindi M,de Mel C,Chandrasena L,Seneviratne SL,Yip C,Yap ES,de Mel S

更新日期：2020-06-01 00:00:00

abstract：:Onchocercal skin disease was measured in 72 onchocerciasis patients from western Uganda, where Simulium neavei is the main transmitting vector of Onchocerca volvulus. The onchocerciasis patients who were HIV-positive had a higher onchocercal skin score compared with those who were HIV-negative (33.7 vs. 19.4, P < 0.00...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kipp W,Bamuhiiga J,Rubaale T

更新日期：2003-05-01 00:00:00

abstract：:An improved enzyme immunoassay technique (EIA) was used in the diagnosis of 311 suspected Russell's viper bite cases in Myanmar [Burma], 181 of whom (58%) had systemic envenoming. Russell's viper venom was detected in the sera of 175 (56.3%), cobra or green pit viper venoms in 4 (1.3%), and no venom in the remaining 1...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Tun-Pe,Ba-Aye,Aye-Aye-Myint,Tin-Nu-Swe,Warrell DA

更新日期：1991-11-01 00:00:00

abstract：:alpha, beta-Arteether is an ethyl ether derivative of artemisinin which is an efficient schizontocidal drug in mild falciparum malaria. The present study reports the efficacy of the drug in severe falciparum malaria. Fifty patients with severe falciparum malaria were given intramuscular arteether, 150 mg, once daily o...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mohanty S,Mishra SK,Satpathy SK,Dash S,Patnaik J

更新日期：1997-05-01 00:00:00

abstract：:The health and human rights communities have much in common. Recently, the international community has begun to devote more attention to the right to the highest attainable standard of health ("the right to health"). Today, this human right presents health and human rights professionals with a range of new opportuniti...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Hunt P

更新日期：2006-07-01 00:00:00

abstract：:From the early 1900s, visceral leishmaniasis (VL; kala-azar) has been among the most important health problems in Sudan, particularly in the main endemic area in the eastern and central regions. Several major epidemics have occurred, the most recent--in Western Upper Nile province in southern Sudan, detected in 1988--...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Zijlstra EE,el-Hassan AM

更新日期：2001-04-01 00:00:00

abstract：:We report the successful treatment of envenoming by the Gaboon viper (Bitis gabonica) and include results of in vitro investigations of the haemostatic properties of the whole venom. The patient was admitted to casualty soon after the bite with chest tightness, dizziness, nausea and swelling at the site of the bite an...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： McNally T,Conway GS,Jackson L,Theakston RD,Marsh NA,Warrell DA,Young L,Mackie IJ,Machin SJ

更新日期：1993-01-01 00:00:00

abstract：:The availability of a defined medium (STEIGER & STEIGER, 1976) has enabled studies on the nutritional requirements of promastigotes of L. donovani and L. braziliensis (STEIGER & STEIGER, 1977). As outlined elsewhere (STEIGER & MESHNICK, 1977), the present paper describes preliminary experiments dealing with the utiliz...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Steiger RF,Meshnick SR

更新日期：1977-01-01 00:00:00

abstract：:Observations on canine leishmaniasis in Morocco (clinical symptoms, diagnosis, evolution, haematology, development of serum proteins, pathology and histopathology) are reported from dogs examined during 1979/80. Special reference is made to infantile kala-azar and its increasing incidence. The public health importance...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kirmse P,Mahin L,Lahrech TM

更新日期：1987-01-01 00:00:00

abstract：:Vector competence of Aedes aegypti populations from six locations in different bioclimatic zones and habitats of Senegal was assessed for sylvatic (ArD 140875) and epidemic (ArA 6894) dengue 2 virus (DENV-2) isolates. F1 generation mosquitoes were fed with a blood meal containing 10(6.5) and 1.6 x 10(7) tissue culture...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Diallo M,Ba Y,Faye O,Soumare ML,Dia I,Sall AA

更新日期：2008-05-01 00:00:00

abstract：:368 strains of Shigella were recovered from stool specimens in the Department of Medical Microbiology, Ahmadu Bello University Teaching Hospital, Zaria, during the period January 1980 to December 1984. S. flexneri was found to be the most common (60%) followed by S. boydii (20.7%), S. dysenteriae (14.1%) and S. sonnei...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Lawande RV,Joshi RM

更新日期：1987-01-01 00:00:00