Evaluation of a new Plasmodium lactate dehydrogenase assay (OptiMAL-IT) for the detection of malaria.

abstract：:A purified 200-kDa antigenic fraction from Leishmania donovani axenic amastigotes was evaluated by ELISA for the detection of antibody response in visceral leishmaniasis (VL) patients, post kala-azar dermal leishmaniasis (PKDL) patients and controls, for the diagnosis of visceral leishmaniasis. A positive antibody res...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kaul P,Malla N,Kaur S,Mahajan RC,Ganguly NK

更新日期：2000-03-01 00:00:00

abstract：:Skin disease is among the most frequent causes of morbidity in Ethiopia, showing high prevalence in the general population and being the sixth most frequent cause of outpatient visits nationwide to health facilities. This study was aimed at describing skin disease patterns in Tigray region, northern Ethiopia through a...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Accorsi S,Barnabas GA,Farese P,Padovese V,Terranova M,Racalbuto V,Morrone A

更新日期：2009-05-01 00:00:00

abstract：:The precise function of Plasmodium falciparum histidine-rich protein II (HRPII) is not known, but in vitro studies have indicated its immunomodulatory function. The host immune response to HRPII was measured and compared with the response to P. falciparum merozoite surface protein 1 (MSP1) in four groups of study subj...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Das P,Grewal JS,Chauhan VS

更新日期：2010-05-01 00:00:00

abstract：:261 individuals were skin tested with leishmanin from Leishmania donovani and with an antigen from a lizard trypanosome isolated in an area endemic for kala-azar in Ethiopia. 83 of the 261 responded positively, with indurations of 5 mm or greater, to one antigen but negatively to the other, and 42 reacted positively t...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Fuller GK,Lemma A,Haile T

更新日期：1980-01-01 00:00:00

abstract：:An improved enzyme immunoassay technique (EIA) was used in the diagnosis of 311 suspected Russell's viper bite cases in Myanmar [Burma], 181 of whom (58%) had systemic envenoming. Russell's viper venom was detected in the sera of 175 (56.3%), cobra or green pit viper venoms in 4 (1.3%), and no venom in the remaining 1...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Tun-Pe,Ba-Aye,Aye-Aye-Myint,Tin-Nu-Swe,Warrell DA

更新日期：1991-11-01 00:00:00

abstract：:Burkitt's lymphoma (BL) accounts for the majority of childhood malignancies seen in sub-Saharan Africa. In Malawi, cyclophosphamide (CPM), the mainstay of treatment for endemic BL, is effective in around 50% of cases. Evidence exists in support of an association between activation of replication of Epstein-Barr virus ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Phillips JA,Griffin BE

更新日期：2007-12-01 00:00:00

abstract：:TB remains a very significant global health burden. There is an urgent need for better tools for TB control, which include an effective vaccine. Bacillus Calmette-Guérin (BCG), the currently licensed vaccine, confers highly variable protection against pulmonary TB, the main source of TB transmission. Replacing BCG com...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Manjaly Thomas ZR,McShane H

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Cryptosporidium spp. are enteric parasites that infect humans and animals. In immunocompromised patients infection can be fatal. This study was conducted to identify sub-populations of Cryptosporidium hominis and C. parvum isolates from HIV-seropositive patients in Equatorial Guinea. METHODS:In a previous s...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Blanco MA,Montoya A,Iborra A,Fuentes I

更新日期：2014-09-01 00:00:00

abstract：:A case-control study was carried out in Kassala and Medani Maternity Hospitals in Sudan to investigate acute-phase proteins [haptoglobin, C-reactive protein (CRP), ferritin and albumin] in three groups of pregnant women (32 in each arm) comprising those with severe Plasmodium falciparum malaria or uncomplicated P. fal...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Saad AA,Mohamed OE,Ali AA,Bashir AM,Ali NI,Elbashir MI,Adam I

更新日期：2012-09-01 00:00:00

abstract：:Leishmanial antigen in circulating immune complexes (CIC) from sera of cotton-rats experimentally infected with Leishmania donovani and visceral leishmaniasis patients (VLP) was detected using a polyethylene glycol (PEG) enzyme-linked immunosorbent assay (PEG-ELISA). The immune complexes were precipitated in the cold ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Azazy AA,Devaney E,Chance ML

更新日期：1994-01-01 00:00:00

abstract：:Major endemic areas of visceral leishmaniasis in Brazil are located in the drier, poorly forested regions, principally in the northeastern States such as Ceará and Bahia. Cases of the human disease in the Amazon Region are rare, very sporadic, and seldom present opportunities for epidemiological study. Following the r...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Silveira FT,Lainson R,Shaw JJ,Póvoa MM

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:To investigate the spatial distribution of congenital syphilis (CS) and its association to social vulnerability indexes in northeast Brazil. METHODS:This was an ecological study referring to all cases of CS and CS deaths recorded in the northeast region of Brazil from 2008 to 2015. Data were obtained from t...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： de Souza CDF,Machado MF,Correia DS,do Carmo RF,Cuevas LE,Santos VS

更新日期：2020-09-01 00:00:00

abstract：:A study was conducted in Mathias Hospital, Yeji, an area of Ghana, where snake bite cases are an important cause of morbidity and mortality, with a case fatality rate of 11% (8/72). Case management difficulties included uncertainty about the assessment of the severity of envenoming, the dosage of antivenom, and the re...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Visser LE,Kyei-Faried S,Belcher DW

更新日期：2004-05-01 00:00:00

abstract：:Diabetic patients, and especially elderly patients in a low-nutritional or immunocompromised state, are prone to a variety of opportunistic infections. 'Myiasis' is a term that refers to non-iatrogenic infestation of tissues by larvae, commonly known as maggots, of dipterous flies. Myiasis as a complication of fractur...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Verettas DA,Chatzipapas CN,Drosos GI,Xarchas KC,Staikos C,Chloropoulou P,Kazakos KI,Ververidis A

更新日期：2008-09-01 00:00:00

abstract：:A range of animal models of Burkholderia pseudomallei infection have been reported, and the host species differ widely both in their susceptibility to infection and in the pathogenesis of disease. In mice, and depending on the route of infection, dose, and mouse strain, the disease can range from a chronic, and in som...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Titball RW,Russell P,Cuccui J,Easton A,Haque A,Atkins T,Sarkar-Tyson M,Harley V,Wren B,Bancroft GJ

更新日期：2008-12-01 00:00:00

abstract：:Because background seroepidemiological data are required before nationwide vaccination against hepatitis B virus (HBV) is attempted, the rate of exposure to HBV was investigated in two high-risk Saudi groups: patients on haemodialysis and patients with congenital bleeding disorders. Although the HBsAg carrier rate was...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Arif M,al-Momen AK,Huraib S,Ramia S

更新日期：1989-03-01 00:00:00

abstract：:Central nervous system involvement due to toxoplasmosis in an immunocompetent host is very rare. We report a case of an immunocompetent patient who presented with suspected tuberculous meningoencephalitis but showed no clinical response to antitubercular therapy. Later, toxoplasmic meningoencephalitis was proved by po...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kaushik RM,Mahajan SK,Sharma A,Kaushik R,Kukreti R

更新日期：2005-11-01 00:00:00

abstract：:Bacteraemia associated with severe malaria in childhood is a sporadically reported phenomenon but its incidence and clinical importance are unknown. We have reviewed clinical and laboratory data from 783 Kenyan children sequentially admitted with a primary diagnosis of severe malaria. The overall incidence of bacterae...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Berkley J,Mwarumba S,Bramham K,Lowe B,Marsh K

更新日期：1999-05-01 00:00:00

abstract：:From the early 1900s, visceral leishmaniasis (VL; kala-azar) has been among the most important health problems in Sudan, particularly in the main endemic area in the eastern and central regions. Several major epidemics have occurred, the most recent--in Western Upper Nile province in southern Sudan, detected in 1988--...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Zijlstra EE,el-Hassan AM

更新日期：2001-04-01 00:00:00

abstract：:A serological study was undertaken to determine the role of arboviruses as etiological agents of encephalitis in the People's Republic of China (PRC). Paired sera were collected during mosquito seasons in 1988-1990 from 614 patients with possible viral encephalitis in 15 regions of PRC and tested for haemagglutination...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Gu HX,Artsob H,Lin YZ,Wang DM,Zhao BY,Long QZ

更新日期：1992-03-01 00:00:00

abstract：:Epidemiological data gathered by the Onchocerciasis Control Programme from 66 villages in West Africa have been analysed. All of these villages were surveyed twice and 10 a third time. The first surveys were conducted around the time when control activities started and provide baseline data against which to assess the...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kirkwood B,Smith P,Marshall T,Prost A

更新日期：1983-01-01 00:00:00

abstract：:The diagnostic performance of procalcitonin and neopterin as markers for bacterial and viral causes of fever was evaluated in a cohort of 69 febrile travellers with known etiological agents. Our aim was to establish a decision rule to minimize empirical antibiotic treatment. Compared with C-reactive protein (CRP) and ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： te Witt R,Hassing RJ,Petit PP,van Belkum A,van Genderen PJ

更新日期：2012-04-01 00:00:00

abstract：:The development and application of interventions for the control of vector-borne zoonoses requires broad understanding of epidemiological linkages between vector, animal infection and human infection. However, there are significant gaps in our understanding of these linkages and a lack of appropriate data poses a cons...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Wardrop NA

更新日期：2016-02-01 00:00:00

abstract：:There is an urgent need for a non-toxic and low-cost treatment for cutaneous leishmaniasis. We synthesised and tested in vivo an amphotericin B-poly(methacrylic acid) drug (AmB-PMA) that had previously shown in-vitro activity against Leishmania major and L. donovani parasites. Efficacy was determined using L. major fo...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Corware KD,Rogers M,Teo I,Müller I,Shaunak S

更新日期：2010-11-01 00:00:00

abstract：:Lymphatic filariasis (LF) caused by Wuchereria bancrofti is widely prevalent in tropical and subtropical countries. Night blood film examination is most commonly used for diagnosis of filariasis but is cumbersome and labour intensive. In order to develop an indirect ELISA-based immunodiagnostic test, the importance of...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Singh A,Kamal S,Rathaur S

更新日期：2010-08-01 00:00:00

abstract：:A new antihookworm compound, C.9333 Go./CGP 4540, was evaluated clinically in 65 adult patients with hookworm infection. Several dosage schedules were evaluated to determine an effective, well tolerated and convenient regime. The lowest effective dose was 125 mg administered at four-hourly intervals for three doses. T...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Vakil BJ,Dalal NJ,Shah PN

更新日期：1977-01-01 00:00:00

abstract：:Tinea imbricata, also known as 'Tokelau', is an uncommon superficial mycosis caused by the anthropophilic dermatophyte Trichophyton concentricum. Cutaneous lesions appear characteristically as scaly and concentric rings that may cover all parts of the body. Often acquired in childhood, tinea imbricata is a chronic dis...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pihet M,Bourgeois H,Mazière JY,Berlioz-Arthaud A,Bouchara JP,Chabasse D

更新日期：2008-04-01 00:00:00

abstract：:Allopurinol and allopurinol ribonucleoside tested in vitro and in vivo for activity against Leishmania donovani. Activity in vitro was low against the amastigote form of this parasite with ED50 values of the order of 54 and 96 microM and 86 and 213 microM respectively for the two compounds. In vivo inhibition of up to...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Neal RA,Croft SL,Nelson DJ

更新日期：1985-01-01 00:00:00

abstract：:Difluoromethylornithine (DFMO), a specific, irreversible inhibitor of polyamine biosynthesis shown to be curative in animal models inoculated with various Trypanosoma spp., was evaluated in the Southern Sudan in a preliminary open clinical field trial in patients infected with Trypanosoma brucei gambiense. 20 patients...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Van Nieuwenhove S,Schechter PJ,Declercq J,Boné G,Burke J,Sjoerdsma A

更新日期：1985-01-01 00:00:00

abstract：:The spread of HIV-1 infection among women of childbearing age has led to increasing numbers of children at risk of vertical transmission. This study aimed to assess child outcomes among HIV-positive (n=19) and AIDS (n=22) mothers from Central West Brazil. CD4(+) T-cell counts (FACScount, BD) and viral loads (HIV-1 RT-...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Alcântara KC,Pereira GA,Albuquerque M,Stefani MM

更新日期：2009-06-01 00:00:00