Identification of Cryptosporidium subtype isolates from HIV-seropositive patients in Equatorial Guinea.

Abstract:

BACKGROUND:Cryptosporidium spp. are enteric parasites that infect humans and animals. In immunocompromised patients infection can be fatal. This study was conducted to identify sub-populations of Cryptosporidium hominis and C. parvum isolates from HIV-seropositive patients in Equatorial Guinea. METHODS:In a previous study conducted in Equatorial Guinea, faecal samples from 171 HIV patients with gastrointestinal symptoms were analyzed. Of these, 13 and 17 were positive for C. hominis and C. parvum, respectively. The isolates were characterized using gp60 gene analysis. RESULTS:The gp60 gene could only be detected in 57% (17/30) of cases (10 C. parvum and 7 C. hominis). Three C. hominis (Ia, Ib and Id) and two C. parvum (IIc and IIe) subtype families were detected, including several subtypes. CONCLUSIONS:The study identified a high diversity of Cryptosporidium subtypes, suggesting that anthroponotic transmission plays an important role in the epidemiology of Cryptosporidium spp. in HIV-seropositive patients in Equatorial Guinea.

authors

Blanco MA,Montoya A,Iborra A,Fuentes I

doi

10.1093/trstmh/tru108

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

594-6

issue

9

eissn

0035-9203

issn

1878-3503

pii

tru108

journal_volume

108

pub_type

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