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Dengue epidemic in the State of Rio Grande do Norte, Brazil, in 1997.

Abstract：

:During 1997 a large dengue epidemic occurred in Rio Grande do Norte, a State in north-east Brazil. The co-circulation of dengue virus type 1 and dengue virus type 2 was demonstrated by virus isolation in Aedes albopictus clone C6/36 cell-line and by reverse transcriptase-polymerase chain reaction (RT-PCR). IgM capture enzyme-linked immunosorbent assay confirmed 52.3% of the 8105 studied cases and dengue antigen was demonstrated by immunohistochemical reaction on hepatocytes from 2 out of 5 fatal cases studied. Individual risk factors for development of dengue haemorrhagic fever/dengue shock syndrome, such as hypertension, diabetes mellitus and bronchial asthma, are discussed.

journal_name

Trans R Soc Trop Med Hyg

journal_title

Transactions of the Royal Society of Tropical Medicine and Hygiene

authors

Cunha RV,Schatzmayr HG,Miagostovich MP,Barbosa AM,Paiva FG,Miranda RM,Ramos CC,Coelho JC,dos Santos FB,Nogueira RM

doi

10.1016/s0035-9203(99)90008-1

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

247-9

issue

3

eissn

0035-9203

issn

1878-3503

journal_volume

93

pub_type

杂志文章

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