Progesterone-induced amoebic liver abscess in guinea-pigs--a new model.

Abstract:

:An experimental model of hepatic amoebiasis in guinea-pigs, simulating the natural infection in man, induced by progesterone following intracaecal inoculation of Entamoeba histolytica has been developed. On Day 3 after infection, 60% of the animals developed amoebic liver abscess, but on Days 7, 11, 15, 20 and 35 after infection liver involvement was recorded in all the animals. No animal in the control group developed hepatic amoebiasis. Severity and frequency of caecal lesions was greater in the control groups than in the experimental group receiving progesterone injections. The antiamoebic antibody levels were slightly higher in the experimental group as compared to the control group.

authors

Gill NJ,Ganguly NK,Mahajan RC,Bhusnurmath SR,Dilawari JB

doi

10.1016/0035-9203(83)90013-5

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

53-8

issue

1

eissn

0035-9203

issn

1878-3503

journal_volume

77

pub_type

杂志文章
  • Dual infections of mice: visceral larva migrans and sublethal infection with Japanese encephalitis virus.

    abstract::Experiments in 3 weeks old albino mice with Toxocara canis and sublethal infection with JE virus established a marked synergestic effect in dually infected mice. The results are discussed to indicate the possible role of visceral larva migrans in creating exploxive outbreaks of "acute encephalopathy syndrome" in indiv...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(75)90018-8

    authors: Pavri KM,Ghalsasi GR,Dastur DK,Goverdhan MK,Lalitha VS

    更新日期:1975-01-01 00:00:00

  • Biological activity of artemisinin-naphthoquine phosphate on Schistosoma haematobium stages and the vector Bulinus truncatus.

    abstract:BACKGROUND:Schistosoma haematobium infection is a major public health problem in most of Africa and the Middle East and praziquantel remains the only drug used for schistosomiasis control, therefore emergence of drug resistance is unavoidable. The antimalarial artemisinin-naphthoquine phosphate combination (co-ArNp) wa...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1093/trstmh/try144

    authors: El-Beshbishi SN,El Bardicy S,Tadros M,Ayoub M,Taman A

    更新日期:2019-06-01 00:00:00

  • Epidemiological features of epidemic cholera (El Tor) in Zimbabwe.

    abstract::Epidemics of cholera have been frequent in southern Africa since the reintroduction of the disease to the continent in 1970. In late 1992, following a severe drought and an influx of refugees from Mozambique, cholera reappeared in Zimbabwe for the first time since 1985 and rapidly spread through the rural areas of the...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(96)90512-x

    authors: Bradley M,Shakespeare R,Ruwende A,Woolhouse ME,Mason E,Munatsi A

    更新日期:1996-07-01 00:00:00

  • Patterns of resistance and DHFR/DHPS genotypes of Plasmodium falciparum in rural Tanzania prior to the adoption of sulfadoxine-pyrimethamine as first-line treatment.

    abstract::A study was carried out to assess the patterns of resistance and occurrence of DHFR/DHPS genotypes of Plasmodium falciparum prior to the adoption of sulfadoxine-pyrimethamine (SP) as first-line treatment for uncomplicated malaria in Tanzania. Children under five years (n = 117) with clinical, uncomplicated malaria wer...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.trstmh.2003.10.010

    authors: Eriksen J,Mwankusye S,Mduma S,Kitua A,Swedberg G,Tomson G,Gustafsson LL,Warsame M

    更新日期:2004-06-01 00:00:00

  • Characterization of Leishmania species from Peru.

    abstract::Twenty-six isolates of Leishmania parasites of Peruvian origin were studied by isoenzyme electrophoresis of four marker enzymes (ASAT, ALAT, G6PD and GPI), kinetoplast DNA hybridization and monoclonal antibody binding and compared with marker strains of the New World organisms L. b. braziliensis, L. b. guyanensis, L. ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(87)90270-7

    authors: Romero GG,Arana M,López M,Montoya I,Bohl R,Campos M,Arévalo J,Llanos A

    更新日期:1987-01-01 00:00:00

  • On the longevity and behaviour of microfilariae of Wuchereria bancrofti, Brugia pahangi and Dirofilaria immitis transfused to laboratory rodents.

    abstract::Microfilariae of Wuchereria bancrofti and Brugia pahangi, which were inoculated into Meriones unguiculatus and Mastomys natalensis respectively, were found in the peripheral blood of the rodents until the ninth day after infection, but no microfilarial periodicity was observed. Microfilariae of W. bancrofti disappeare...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(80)90054-1

    authors: Zielke E

    更新日期:1980-01-01 00:00:00

  • Treatment outcome of patients with smear-negative and smear-positive pulmonary tuberculosis in the National Tuberculosis Control Programme, Malawi.

    abstract::National tuberculosis control programmes (NTPs) in sub-Saharan Africa do not routinely record or report treatment outcome data on smear-negative pulmonary tuberculosis (PTB) patients. Twelve-month treatment outcome on patients with smear-negative PTB registered in all district and mission hospitals in Malawi during th...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(99)90153-0

    authors: Harries AD,Nyirenda TE,Banerjee A,Boeree MJ,Salaniponi FM

    更新日期:1999-07-01 00:00:00

  • Concurrence of dermatological and ophthalmological morbidity in onchocerciasis.

    abstract::Prevalence of skin and eye disorders in African onchocerciasis (river blindness) is well documented. However, less is known about their joint occurrence. Information on concurrence may improve our understanding of disease pathogenesis and is required to estimate the disease burden of onchocerciasis. We analysed data f...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.trstmh.2011.12.006

    authors: Coffeng LE,Fobi G,Ozoh G,Bissek AC,Nlatté BO,Enyong P,Olinga JM,Zouré HG,Habbema JD,Stolk WA,de Vlas SJ,Boussinesq M,Noma M

    更新日期:2012-04-01 00:00:00

  • A trial of Fansidar plus chloroquine or Fansidar alone for the treatment of uncomplicated malaria in Gambian children.

    abstract::Chloroquine can no longer be recommended as the first-line treatment for uncomplicated malaria in several parts of Africa because of the increasing prevalence of chloroquine resistance. However, chloroquine was a highly effective treatment for malaria not only because of its ability to kill parasites quickly but also ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0035-9203(98)90962-2

    authors: Bojang KA,Schneider G,Forck S,Obaro SK,Jaffar S,Pinder M,Rowley J,Greenwood BM

    更新日期:1998-01-01 00:00:00

  • Evaluation of perinatal and intrafamilial hepatitis B prevention programmes in a well child clinic: 9-year follow-up study in Turkey.

    abstract::Evaluating the performance of well child clinics on adherence to recommended perinatal hepatitis B prevention programmes as well as assessing the outcome of infants living with hepatitis B surface antigen (HBsAg)-positive parents is important. A retrospective study was performed of 336 babies who had at least one HBsA...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2010.12.001

    authors: Polat S,Camurdan AD,Aksakal N,Agladioglu S,Beyazova U,Sahin F,Atak A,Er A

    更新日期:2011-04-01 00:00:00

  • A randomized double-blind placebo-controlled field trial of ivermectin and albendazole alone and in combination for the treatment of lymphatic filariasis in Ghana.

    abstract::The efficacy and safety of single-dose ivermectin (150-200 micrograms/kg) and albendazole (400 mg) treatment administered separately or in combination for Wuchereria bancrofti infections were assessed in 1996-98 in a randomized double-blind placebo-controlled field trial in Ghana: 1425 individuals from 4 lymphatic fil...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0035-9203(00)90278-5

    authors: Dunyo SK,Nkrumah FK,Simonsen PE

    更新日期:2000-03-01 00:00:00

  • High prevalence of toxinogenic Clostridium difficile in Nigerian adult HIV patients.

    abstract::Clostridium difficile is the most commonly identified bacterial cause of nosocomial and HIV-related diarrhea. In many developing countries, antibiotic access is unregulated. Nigeria has the third highest HIV burden worldwide. Due to perceptions of low prevalence and resource incapacity, patients with diarrhea are not ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.trstmh.2011.07.014

    authors: Onwueme K,Fadairo Y,Idoko L,Onuh J,Alao O,Agaba P,Lawson L,Ukomadu C,Idoko J

    更新日期:2011-11-01 00:00:00

  • Arboviruses as aetiological agents of encephalitis in the People's Republic of China.

    abstract::A serological study was undertaken to determine the role of arboviruses as etiological agents of encephalitis in the People's Republic of China (PRC). Paired sera were collected during mosquito seasons in 1988-1990 from 614 patients with possible viral encephalitis in 15 regions of PRC and tested for haemagglutination...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(92)90569-x

    authors: Gu HX,Artsob H,Lin YZ,Wang DM,Zhao BY,Long QZ

    更新日期:1992-03-01 00:00:00

  • Cultivation of fertile Plasmodium falciparum gametocytes in semi-automated systems. 1. Static cultures.

    abstract::A semi-automated cultivation apparatus for the in vitro culture of Plasmodium falciparum gametocytes is described. This apparatus has been designed to produce large numbers of fertile sexual stages for use in the development of a gamete vaccine or for the infection of suitable mosquitoes. These mosquitoes in turn may ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(82)90116-x

    authors: Ponnudurai T,Lensen AH,Leeuwenberg AD,Meuwissen JH

    更新日期:1982-01-01 00:00:00

  • Causal prophylactic efficacy of atovaquone-proguanil (Malarone) in a human challenge model.

    abstract::Plasmodia infect the liver for about 7 days before subsequently infecting the blood. Present prophylaxis against Plasmodium falciparum malaria employs agents that primarily kill blood stages and must be continued for 28 days after the last exposure. Atovaquone-proguanil (Malarone) is a new antimalarial agent that is l...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0035-9203(01)90206-8

    authors: Berman JD,Nielsen R,Chulay JD,Dowler M,Kain KC,Kester KE,Williams J,Whelen AC,Shmuklarsky MJ

    更新日期:2001-07-01 00:00:00

  • Development of antibody to Rickettsia tsutsugamushi in soldiers in Malaysia.

    abstract::Malaysian, British and New Zealand soldiers were tested for evidence of infection with Rickettsia tsutsugamushi after several weeks' exposure to the infection during field exercises in Malaysia. 39 (5.0%) of 787 British and New Zealand soldiers developed immunofluorescent antibody (IFA) to R. tsutsugamushi to a titre ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(83)90079-2

    authors: Brown GW,Shirai A,Groves MG

    更新日期:1983-01-01 00:00:00

  • Predisposition of individuals and families in Mexico to heavy infection with Ascaris lumbricoides and Trichuris trichiura.

    abstract::Stool specimens from 90% of the population of 2 marginal communities in Coatzacoalcos, Mexico, were examined by the Kato-Katz technique for the estimation of eggs per gram of faeces (epg). Average epg values for Ascaris lumbricoides and Trichuris trichiura were calculated for each family in the community, based on the...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(90)90284-l

    authors: Forrester JE,Scott ME,Bundy DA,Golden MH

    更新日期:1990-03-01 00:00:00

  • Enteropathogenic and enterotoxigenic Escherichia coli as aetiological factors of infantile diarrhoea in rural and urban Ghana.

    abstract::There are 4 recognized classes of Escherichia coli that cause diarrhoeal disease in humans: enteropathogenic (EPEC), enterotoxigenic (ETEC), enteroinvasive (EIEC), and enterohaemorrhagic E. coli (EHEC). Preliminary analysis of enterotoxin production in a rural community in Ghana showed a prevalence of 11.0% LT-ST+, 9....

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(88)90173-3

    authors: Agbodaze D,Abrahams CA,Arai S

    更新日期:1988-01-01 00:00:00

  • Problems of chemotherapy in multiply-infected AIDS patients.

    abstract::Potential multiple opportunistic infections in patients with the acquired immune deficiency syndrome (AIDS) cause the clinician considerable problems. Firstly there is the problem of the correct diagnosis of which organism is producing symptoms and there is the possibility of more than one organism being responsible. ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章,评审

    doi:10.1016/0035-9203(90)90452-k

    authors: Gazzard BG

    更新日期:1990-01-01 00:00:00

  • Prevalence and clinical presentation of glucose-6-phosphate dehydrogenase deficiency in Pakistani Pathan and Afghan refugee communities in Pakistan; implications for the use of primaquine in regional malaria control programmes.

    abstract::Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency surveys in Afghan refugees and a local community in the North-West Frontier Province, Pakistan, showed that this trait was most common among Pathan and Uzbak refugees (15.8% and 9.1% respectively). The prevalence among Pakistani Pathans was 7.0%, and that in Tajik ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(95)90661-4

    authors: Bouma MJ,Goris M,Akhtar T,Khan N,Khan N,Kita E

    更新日期:1995-01-01 00:00:00

  • The sickle cell gene is widespread in India.

    abstract::The sickle cell gene was first described in India in a tribal population in the south, leading to the belief that it was confined to tribal groups. The present study confirms that it is widespread in the state of Orissa and spreads throughout Hindu society, being more common in upper and scheduled castes than in triba...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(87)90239-2

    authors: Kar BC,Devi S,Dash KC,Das M

    更新日期:1987-01-01 00:00:00

  • Serological and blood culture investigations of Nepalese fever patients.

    abstract::Serological testing of paired (i.e. admission and convalescent) sera from 103 fever patients in Kathmandu, Nepal, was performed to estimate the prevalence rates of scrub typhus, murine typhus, Leptospira and dengue virus antibodies and to determine their role in the cause of active infections. Blood cultures from 15 p...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2007.02.015

    authors: Blacksell SD,Sharma NP,Phumratanaprapin W,Jenjaroen K,Peacock SJ,White NJ,Pukrittayakamee S,Day NP

    更新日期:2007-07-01 00:00:00

  • Wuchereria bancrofti in Tanzania: immune reactions to the microfilarial surface, and the effect of diethylcarbamazine upon these reactions.

    abstract::Immune reactions to the surface of microfilariae (mff) of Wuchereria bancrofti were investigated among persons living in an endemic filariasis area of Tanzania. The sera from a proportion of mff-negative persons contained antibodies to the microfilarial sheath, and a clear correlation was seen between presence of anti...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(85)90137-3

    authors: Simonsen PE

    更新日期:1985-01-01 00:00:00

  • An amphotericin B-based drug for treating experimental Leishmania major infection.

    abstract::There is an urgent need for a non-toxic and low-cost treatment for cutaneous leishmaniasis. We synthesised and tested in vivo an amphotericin B-poly(methacrylic acid) drug (AmB-PMA) that had previously shown in-vitro activity against Leishmania major and L. donovani parasites. Efficacy was determined using L. major fo...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2010.08.010

    authors: Corware KD,Rogers M,Teo I,Müller I,Shaunak S

    更新日期:2010-11-01 00:00:00

  • Schistosomiasis prophylaxis in vivo using N,N-diethyl-m-toluamide (DEET).

    abstract::Topical N,N-Diethyl-m-toluamide (DEET) was studied as a schistosomiasis prophylactic in vivo for the use of individuals with limited exposure. Fifteen subjects, on a 3-week expedition to Lake Malawi in September 2001, applied 50% DEET to their skin after exposure to lake water. No subjects developed evidence of a new ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0035-9203(03)90087-3

    authors: Jackson F,Doherty JF,Behrens RH

    更新日期:2003-07-01 00:00:00

  • Presence of antibodies against Leishmania chagasi in haemodialysed patients.

    abstract::In the last decades there has been an increase in cases of visceral leishmaniasis complicating the post-transplant phase, mainly following kidney transplantation. The aim of this study was to evaluate the reactivity of haemodialysed patients using IFAT. Blood samples of 310 individuals from Natal, RN, Brazil, were col...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2009.01.003

    authors: Souza RM,de Oliveira IB,Paiva VC,Lima KC,dos Santos RP,de Almeida JB,Luz KG

    更新日期:2009-07-01 00:00:00

  • Isolation of Trichophyton concentricum from chronic cutaneous lesions in patients from the Solomon Islands.

    abstract::Tinea imbricata, also known as 'Tokelau', is an uncommon superficial mycosis caused by the anthropophilic dermatophyte Trichophyton concentricum. Cutaneous lesions appear characteristically as scaly and concentric rings that may cover all parts of the body. Often acquired in childhood, tinea imbricata is a chronic dis...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2008.01.002

    authors: Pihet M,Bourgeois H,Mazière JY,Berlioz-Arthaud A,Bouchara JP,Chabasse D

    更新日期:2008-04-01 00:00:00

  • Highly pyrimethamine-resistant alleles of dihydrofolate reductase in isolates of Plasmodium falciparum from Tanzania.

    abstract::In 2000 we used a sensitive technique to examine 9 isolates from malaria patients in Muheza, Tanzania who had failed treatment with sulfadoxine-pyrimethamine (SP). Three isolates carried, at low levels, the leucine to isoleucine change at amino acid 164 that is associated with clinical failure of SP. Numerous other hi...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(02)90349-4

    authors: Hastings MD,Bates SJ,Blackstone EA,Monks SM,Mutabingwa TK,Sibley CH

    更新日期:2002-11-01 00:00:00

  • Sero-epidemiology of rubella in Imo State of Nigeria.

    abstract::931 serum samples collected at random from healthy subjects in the four health zones of Imo State were analysed for the presence of rubella haemagglutination inhibition antibodies. Rubella antibodies were present in 625 of the samples giving a prevalence of 66.6%. There was a gradual increase in the prevalence of thes...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(85)90114-2

    authors: Gomwalk NE,Ezeronye OU

    更新日期:1985-01-01 00:00:00

  • An outbreak of plague including cases with probable pneumonic infection, Ecuador, 1998.

    abstract::During February and March of 1998, 12 sudden deaths were reported among residents of a high-Andean community in Ecuador. All 12 fatalities were members of the same extended family and some had apparent exposure to sick guinea-pigs. Following an initial investigation by public health officials, an additional death was ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(00)90114-7

    authors: Gabastou JM,Proaño J,Vimos A,Jaramillo G,Hayes E,Gage K,Chu M,Guarner J,Zaki S,Bowers J,Guillemard C,Tamayo H,Ruiz A

    更新日期:2000-07-01 00:00:00