The sickle cell gene is widespread in India.

abstract：:Eighty-seven Egyptians with Schistosoma haematobium infection (current or past) and chronic dysuria seen at the Theodor Bilharz Research Institute outpatient urology clinic in Imbaba, Cairo, Egypt were investigated for Chlamydia trachomatis infection. Direct fluorescent antibody tests (DFAT) showed 30 urethral swabs (...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Haberberger RL Jr,Mokhtar S,Badawy H,Abu-Elyazeed R

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the impact of sputum quality and quantity on smear and culture positivity for Mycobacterium tuberculosis. METHODS:A total of 14 708 sputum specimens, collected from respiratory symptomatics in a TB prevalence survey, were evaluated for gross appearance and volume of...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Bhat J,Rao V,Muniyandi M,Yadav R,Karforma C,Luke C

更新日期：2014-01-01 00:00:00

abstract：:A hypervariable deoxyribonucleic acid (DNA) probe was isolated by screening a Leishmania donovani genomic DNA library with L. donovani total DNA. The probe was used to characterize L. donovani stocks on the basis of restriction fragment length polymorphisms (RFLPs). The molecular karyotype of the same stocks was exami...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Bishop RP,Akinsehinwa F

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Bacteria are sources of numerous molecules used in treatment of infectious diseases. We investigated effects of molecules produced by 26 Pseudomonas aeruginosa strains against infection of mammalian cell cultures with Trypanosoma cruzi, the aetiological agent of Chagas disease. METHODS:Vero cells were infec...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sass G,Miller Conrad LC,Nguyen TH,Stevens DA

更新日期：2020-07-01 00:00:00

abstract：:Immune responsiveness of schistosomiasis patients was assayed longitudinally, before and for two years after chemotherapeutic treatment with praziquantel, by in vitro peripheral blood mononuclear cell (PBMN) proliferation upon exposure to phytohaemagglutinin (PHA), or soluble schistosomal antigenic preparations from e...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Colley DG,Barsoum IS,Dahawi HS,Gamil F,Habib M,el Alamy MA

更新日期：1986-01-01 00:00:00

abstract：:We describe here a method, potentially suitable for field applications, for semi-quantitative detection of Mycobacterium leprae antigens in skin scrapings, which are taken normally for smear microscopy. Thirty acid-fast bacilli-negative paucibacillary (PB) leprosy patients comprised the main study group; eight acid-fa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Chaturvedi V,Girdhar BK,Sengupta U,Sinha S

更新日期：2007-07-01 00:00:00

abstract：:Mebendazole, a benzimidazole carbamate compound, is currently in use for human medical practice against soil-transmitted helminthiasis (STH) and enterobiasis. However, it has been demonstrated that its spectrum of activity is broad and goes beyond those infections. Several studies provide evidence that this drug, take...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Cañete R,Escobedo AA,Almirall P,González ME,Brito K,Cimerman S

更新日期：2009-05-01 00:00:00

abstract：:A study was carried out to assess the patterns of resistance and occurrence of DHFR/DHPS genotypes of Plasmodium falciparum prior to the adoption of sulfadoxine-pyrimethamine (SP) as first-line treatment for uncomplicated malaria in Tanzania. Children under five years (n = 117) with clinical, uncomplicated malaria wer...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Eriksen J,Mwankusye S,Mduma S,Kitua A,Swedberg G,Tomson G,Gustafsson LL,Warsame M

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Cryptosporidium spp. are enteric parasites that infect humans and animals. In immunocompromised patients infection can be fatal. This study was conducted to identify sub-populations of Cryptosporidium hominis and C. parvum isolates from HIV-seropositive patients in Equatorial Guinea. METHODS:In a previous s...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Blanco MA,Montoya A,Iborra A,Fuentes I

更新日期：2014-09-01 00:00:00

abstract：:The severity and consequences of human Trichuris infection vary widely. This may reflect differences in immune response. T. muris is a natural parasite of mice which provides a close, well defined, easily manipulated model for otherwise uninvestigatable aspects of this response. Normal mice reject the parasite in 3 we...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Jenkins D,Wakelin D

更新日期：1994-05-01 00:00:00

abstract：:A semi-automated cultivation apparatus for the in vitro culture of Plasmodium falciparum gametocytes is described. This apparatus has been designed to produce large numbers of fertile sexual stages for use in the development of a gamete vaccine or for the infection of suitable mosquitoes. These mosquitoes in turn may ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ponnudurai T,Lensen AH,Leeuwenberg AD,Meuwissen JH

更新日期：1982-01-01 00:00:00

abstract：:The harmful effects of malaria are most pronounced during first pregnancies and chemoprophylaxis is most effective when given at this time. However, restriction of chemoprophylaxis to first pregnancies might lead to enhanced susceptibility to malaria during second pregnancies. We have investigated this possibility by ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Greenwood AM,Menendez C,Alonso PL,Jaffar S,Langerock P,Lulat S,Todd J,M'Boge B,Francis N,Greenwood BM

更新日期：1994-11-01 00:00:00

abstract：:We investigated whether the polymerase chain reaction (PCR) performed with aspirates of bone marrow or lymph node can be used as a test of cure of visceral leishmaniasis (VL). Sixty-one VL patients who had received supervised treatment with sodium stibogluconate in the health centre of Médecins sans Frontières (MSF) H...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Osman OF,Oskam L,Zijlstra EE,el-Hassan AM,el-Naeim DA,Kager PA

更新日期：1998-07-01 00:00:00

abstract：:We have studied the distribution of rheumatoid factor isotypes amongst patients with loiasis with and without accompanying glomerulonephritis to determine the possible role of rheumatoid factor antiglobulins in this disease. Our findings indicate an increase in both immunoglobulin (Ig) G and IgM rheumatoid factor isot...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Adebajo AO,Akinsola A,Maizels RM,Cawston TE,Hazleman BL

更新日期：1992-11-01 00:00:00

abstract：:Although diethylcarbamazine (DEC) and albendazole are recommended to interrupt transmission of Wuchereria bancrofti, little is known about the macrofilaricidal effect of this drug combination. Forty-seven men with W. bancrofti infection were randomly assigned to receive a single dose of either DEC alone (6 mg/kg) (n=2...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Dreyer G,Addiss D,Williamson J,Norões J

更新日期：2006-12-01 00:00:00

abstract：:This article reviews peer-reviewed publications and book chapters on the history, epidemiology, genetics, ecology, pathogenesis, pathology and management of podoconiosis (endemic non-filarial elephantiasis). Podoconiosis is a non-infectious geochemical elephantiasis caused by exposure of bare feet to irritant alkalic ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Davey G,Tekola F,Newport MJ

更新日期：2007-12-01 00:00:00

abstract：:An evaluation of the performance of the Kersey Nutrition Rehabilitation Centre in Nigeria was undertaken with particular focus on mortality, rate of weight gain, and the management strategy. During 1987-1991 the total number of admissions for protein-energy malnutrition (PEM) was 803. The age group most commonly repre...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ibekwe VE,Ashworth A

更新日期：1994-09-01 00:00:00

abstract：:Response to treatment with organic pentavalent antimonials, the standard first-line treatment for visceral leishmaniasis (VL), has been decreasing since their introduction into India. Combining sodium stibogluconate (SB) with paromomycin (PM) may be an efficient alternative to single-agent therapy. This trial was desi...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Thakur CP,Kanyok TP,Pandey AK,Sinha GP,Zaniewski AE,Houlihan HH,Olliaro P

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:To investigate the spatial distribution of congenital syphilis (CS) and its association to social vulnerability indexes in northeast Brazil. METHODS:This was an ecological study referring to all cases of CS and CS deaths recorded in the northeast region of Brazil from 2008 to 2015. Data were obtained from t...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： de Souza CDF,Machado MF,Correia DS,do Carmo RF,Cuevas LE,Santos VS

更新日期：2020-09-01 00:00:00

abstract：:This paper is a report of the first year of follow-up on 250 pre-school children in a village in Ghana. The mean weight for age and the mean height for age at the start of the study, ranged between 81 and 97% and 91 and 101.4% of the median WHO reference standards respectively. Classified according to Waterlow (1973) ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Biritwum RB,Isomura S,Assoku A,Torigoe S

更新日期：1986-01-01 00:00:00

abstract：:Following the successful eradication of Brucella abortus infection in cattle, human brucellosis in England and Wales has become an uncommon imported disease. Culture of the organism presents a major laboratory hazard, and difficulties in identification may occur using a biochemical test-strip method. An overview of re...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Luzzi GA,Brindle R,Sockett PN,Solera J,Klenerman P,Warrell DA

更新日期：1993-03-01 00:00:00

abstract：:In 1991, a study on Wuchereria bancrofti microfilariae (mf) and infection rates was carried out in the human and mosquito populations of a Polynesian village where, 10 years before, the mf prevalence rate was 6.4% and twice-yearly mass treatment with 3 mg/kg of diethylcarbamazine (DEC) was interrupted. Venous blood sa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Cartel JL,Nguyen NL,Spiegel A,Moulia-Pelat JP,Plichart R,Martin PM,Manuellan AB,Lardeux F

更新日期：1992-07-01 00:00:00

abstract：:Between July 1989 and December 1990, 4504 new adult patients with tuberculosis were screened for antibodies to human immunodeficiency viruses (HIV) 1 and 2 in Abidjan's 2 tuberculosis treatment centres. The prevalence levels of HIV-1 and HIV-2 infections were 30.2% and 4.2% respectively, a further 9.3% of patients rea...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Gnaore E,Sassan-Morokro M,Kassim S,Ackah A,Yesso G,Adjorlolo G,Digbeu H,Coulibaly D,Coulibaly IM,Doorly R

更新日期：1993-01-01 00:00:00

abstract：:Accurate identification of Leishmania species is important for monitoring clinical outcome, adequately targeting treatment, and evaluation of epidemiological risk in tegumentary leishmaniasis. This is especially the case in regions where several species coexist and for travel medicine where the geographical source of ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Victoir K,De Doncker S,Cabrera L,Alvarez E,Arevalo J,Llanos-Cuentas A,Le Ray D,Dujardin JC

更新日期：2003-01-01 00:00:00

abstract：:Leishmania mexicana mexicana amastigote proteinase activity was largely inhibited by low concentrations of leupeptin, antipain and two epoxysuccinates, compounds known to affect cysteine proteinases. Of these inhibitors, only two had leishmanicidal activity. trans-Dicyclohexylepoxysuccinate at 10 microgram/ml inhibite...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Coombs GH,Hart DT,Capaldo J

更新日期：1982-01-01 00:00:00

abstract：:Eleven heterogeneous patients with inoperable hydatid disease were treated with high doses of oral mebendazole, up to 200 mg/kg/day for 16 to 48 weeks. Toxicity was not encountered. Despite careful assessment it proved difficult critically to evaluate the efficacy of mebendazole. In four patients chemotherapy appeared...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Bryceson AD,Cowie AG,Macleod C,White S,Edwards D,Smyth JD,McManus DP

更新日期：1982-01-01 00:00:00

abstract：:The vector potential of Culicoides variipennis for Rift Valley fever virus (RVFV) was investigated. Insects from a colony maintained at the Animal Virus Research Institute, Pirbright, were fed through a membrane on a mixture of mouse blood and RVFV (virus concentration of blood meal 7 X 95 log10 MLD50ml). Engorged ins...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Jennings M,Platt GS,Bowen ET

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Characterization of the epidemiology of Escherichia coli bloodstream infection (BSI) in sub-Saharan Africa is lacking. We studied patients with E. coli BSI in northern Tanzania to describe host risk factors for infection and to describe the antimicrobial susceptibility of isolates. METHODS:Within 24 h of ad...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Madut DB,Rubach MP,Kalengo N,Carugati M,Maze MJ,Morrissey AB,Mmbaga BT,Lwezaula BF,Kilonzo KG,Maro VP,Crump JA

更新日期：2020-05-07 00:00:00

abstract：:The market for antimalarial drugs consists of the 2.8 billion (2.8 x 10(9) people living in malaria endemic areas and about 20-30 million people, mainly Europeans and North Americans, who travel or live in malarious areas, and the wealthy elite of malarious developing countries. Some of the largest markets include Chi...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Foster S

更新日期：1994-06-01 00:00:00

abstract：:A population-based study of the clinical, laboratory and ultrasonographic findings in patients suffering from mild or moderate opisthorchiasis in Prachinburi province, Thailand was conducted in 1990-1992. The effectiveness of treatment with praziquantel at 40 mg/kg body weight was evaluated. After treatment, a long-la...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pungpak S,Chalermrut K,Harinasuta T,Viravan C,Schelp PF,Hempfling A,Schlattmann P,Bunnag D

更新日期：1994-09-01 00:00:00