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High prevalence of toxinogenic Clostridium difficile in Nigerian adult HIV patients.

Abstract：

:Clostridium difficile is the most commonly identified bacterial cause of nosocomial and HIV-related diarrhea. In many developing countries, antibiotic access is unregulated. Nigeria has the third highest HIV burden worldwide. Due to perceptions of low prevalence and resource incapacity, patients with diarrhea are not tested for toxinogenic C. difficile infection (CDI). In this pilot study which included 97 HIV-positive patients at two hospitals in Nigeria, the estimated prevalence of CDI was 43% and 14% for in-patients and out-patients respectively. HIV-positive out-patients were more likely to have toxinogenic CDI than non-HIV out-patients (P=0.007, Fisher's exact test).

journal_name

Trans R Soc Trop Med Hyg

journal_title

Transactions of the Royal Society of Tropical Medicine and Hygiene

authors

Onwueme K,Fadairo Y,Idoko L,Onuh J,Alao O,Agaba P,Lawson L,Ukomadu C,Idoko J

doi

10.1016/j.trstmh.2011.07.014

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

667-9

issue

11

eissn

0035-9203

issn

1878-3503

pii

S0035-9203(11)00147-7

journal_volume

105

pub_type

杂志文章,多中心研究

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