An epidemic of meningococcal infection at Zaria, Northern Nigeria. 2. The changing clinical pattern.

abstract：:Geophagy has been associated with iron deficiency and anaemia, but no causal relationship has been established. To clarify this, we conducted a two-by-two factorial randomised, controlled trial on the effect of iron and multimicronutrient supplementation on geophagy in Zambian schoolchildren in Lusaka, from February t...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Nchito M,Geissler PW,Mubila L,Friis H,Olsen A

更新日期：2004-04-01 00:00:00

abstract：:In order to estimate the importance as a public health problem of skin diseases, we investigated the prevalence and severity of skin diseases in a representative sample of children in Mali. 1817 children were randomly selected in 30 clusters by probability-proportional-to-size sampling in Koulikoro region. The mean pr...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mahé A,Prual A,Konaté M,Bobin P

更新日期：1995-09-01 00:00:00

abstract：:Trypanosoma cruzi (Brazil strain) was maintained in liver infusion tryptose and medium supplemented with 5 or 10% foetal calf serum at 27 degrees C on a rotating shaker platform. 85 to 95% of the organisms under these conditions are epimastigotes and the medium supported logarithmic growth for up to 24 hours. The effe...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Nadler JP,Lederer E,Wittner M,Baum SG,Tanowitz HB

更新日期：1982-01-01 00:00:00

abstract：:In 2005-2006, a large outbreak of Chikungunya (CHIK) fever occurred on the western Indian Ocean Islands. In Mayotte, concurrent with an enhanced passive case notification system, we carried out two surveys. A seroprevalence survey designed to document recent CHIK infection was conducted on serum samples collected from...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sissoko D,Malvy D,Giry C,Delmas G,Paquet C,Gabrie P,Pettinelli F,Sanquer MA,Pierre V

更新日期：2008-08-01 00:00:00

abstract：:Visceral leishmaniasis (VL) was experimentally induced in rhesus macaques (Macaca mulatta) by intravenously inoculating 2 x 10(7)amastigotes/kg of body weight of Leishmania infantum. The macaques developed a systemic disease showing characteristic features of human VL such as fever, diarrhoea, body weight loss, anaemi...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Porrozzi R,Pereira MS,Teva A,Volpini AC,Pinto MA,Marchevsky RS,Barbosa AA Jr,Grimaldi G Jr

更新日期：2006-10-01 00:00:00

abstract：:A survey was conducted for serum neutralizing antibodies against 3 members of the Lyssavirus group (rabies, Lagos bat and Mokola viruses) in Nigerian dogs and humans. Of 463 unvaccinated dogs sampled, 142 (30.7%) had antibodies against rabies; 39.2% of the stray dogs were positive. Of 241 dogs tested, 17.4% had antibo...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ogunkoya AB,Beran GW,Umoh JU,Gomwalk NE,Abdulkadir IA

更新日期：1990-11-01 00:00:00

abstract：:The extensively drug-resistant tuberculosis (XDR-TB) categorisation has been developed as a phenotypic description of those TB strains that are resistant to most conventional anti-TB drugs. While widely accepted to have significant incidence in those areas, such as Eastern Europe, that have high levels of multidrug re...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Jones KD,Hesketh T,Yudkin J

更新日期：2008-03-01 00:00:00

abstract：:In 25 cases of pellagra and 10 healthy controls, the blood pyruvic acid levels in the fasting stage and after 60 and 90 minutes of glucose load were estimated by the technique of Friedmann & Haugen (1943). The blood pyruvic acid levels after 60 and 90 minutes of glucose load were significantly higher in pellagrins as ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Bedi HK,Bomb BS,Agarwal MP,Bhatnagar LK

更新日期：1977-01-01 00:00:00

abstract：:Data on malaria transmission intensity and prevalences of asexual parasites and of gametocytes were obtained in an urban district of Yaoundé, Cameroon. The transmission level from mosquito to human was determined by indoor night capture of mosquitoes on human volunteers, revealing a calculated entomological inoculatio...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： van der Kolk M,Tebo AE,Nimpaye H,Ndombol DN,Sauerwein RW,Eling WM

更新日期：2003-07-01 00:00:00

abstract：:Hungry Anopheles funestus females were caught in CDC light traps positioned overnight in village houses in which the occupants were protected by bed nets. The sampling was performed in six huts near Muheza, in North-eastern Tanzania, September to November 1972. Parous, unfed mosquitoes were carefully examined, usually...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Krafsur ES,Garrett-Jones C

更新日期：1977-01-01 00:00:00

abstract：:The red fox is considered to be the main reservoir of the present European rabies epizootic which began in Poland in 1939-40. Its usual rate of spread is 20 to 60 km a year. Mortality among rabies-infected fox populations is estimated variously to be 20 to 60%. The infection spreads more rapidly among foxes in the aut...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Lloyd HG

更新日期：1976-01-01 00:00:00

abstract：:To compare the characteristics of women and men with Trypanosoma brucei gambiense trypanosomiasis, all 3231 cases treated in Nioki hospital, Democratic Republic of Congo, from 1982 to 2000 were reviewed for demographic information, date and mode of diagnosis, pre-treatment cerebrospinal fluid (CSF) examination, treatm...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Pépin J,Mpia B,Iloasebe M

更新日期：2002-07-01 00:00:00

abstract：:In the Omdurman Hospital for Tropical Diseases, Sudan, from 6 October to 1 December 1986, 736 patients with cutaneous leishmaniasis (CL) were studied. The duration of the lesions varied from a few days to 4 months, usually (56%) 1-3 months. Multiple lesions ranging from one to 50 (mean = 4) were present in 80% of case...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： el-Safi SH,Peters W,el-Toam B,el-Kadarow A,Evans DA

更新日期：1991-07-01 00:00:00

abstract：:Using the IgG fraction of a monospecific sheep antiserum against the circulating anodic antigen (CAA) of Schistosoma mansoni, an indirect haemagglutination reaction for the determination of this antigen was developed. This is the first time that an IHA has been applied to the detection of circulating antigens in paras...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Deelder AM,Eveleigh PC

更新日期：1978-01-01 00:00:00

abstract：Background:Severe cholera is a life-threatening illness of hypovolemic shock and metabolic acidosis due to rapid and profuse diarrheal fluid loss. Emergency life-saving therapy is i.v. saline, optionally supplemented with potassium and alkali to correct the fluid deficit, potassium losses and acidosis. After this initi...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Butler T

更新日期：2017-05-01 00:00:00

abstract：:Investigations to characterize the in vitro reaction of serum-mediated leucocyte-adherence to microfilariae of Wuchereria bancrofti were carried out in Tanzania. The adherence reaction took place within one hour and at least two serum factors were involved: a heat-labile factor, present also in normal serum (probably ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Simonsen PE

更新日期：1983-01-01 00:00:00

abstract：:A new antihookworm compound, C.9333 Go./CGP 4540, was evaluated clinically in 65 adult patients with hookworm infection. Several dosage schedules were evaluated to determine an effective, well tolerated and convenient regime. The lowest effective dose was 125 mg administered at four-hourly intervals for three doses. T...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Vakil BJ,Dalal NJ,Shah PN

更新日期：1977-01-01 00:00:00

abstract：:The sensitivity specificity of an enzyme-linked immunosorbent assay (ELISA) for the serodiagnosis of strongyloidiasis has been investigated. 45 men with long-standing strongyloidiasis were compared with the same number of age- and sex-matched control subjects. The ELISA detected antibody in 84% of patients with parasi...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Carroll SM,Karthigasu KT,Grove DI

更新日期：1981-01-01 00:00:00

abstract：:Niclosamide was used to interrupt transmission of Schistosoma haematobium by Bulinus senegalensis in seasonal rainwater pools for a period of three years. Snail populations were progressively reduced to approximately 1% of the numbers in untreated pools. There was little or no evidence of acquisition of new infection ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Goll PH,Wilkins HA,Marshall TF

更新日期：1984-01-01 00:00:00

abstract：:Entamoeba histolytica trophozoites isolated in Robinson's medium from faeces containing cysts, transported from India, have been tested in vitro against the drugs furazolidone, iodochlorhydroxyquin, and both drugs combined as Dependal. Results show the levels at which drug action is significant and that interaction be...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sargeaunt PG,Lumsden WH

更新日期：1976-01-01 00:00:00

abstract：:Young African children with severe malaria are given quinine using a regimen designed for Thai adults. We measured quinine in the blood, plasma and plasma water of young children in Kenya after rapid intravenous and intramuscular dosing, and calculated the therapeutic range of unbound quinine. The peak plasma quinine ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Winstanley P,Newton C,Watkins W,Mberu E,Ward S,Warn P,Mwangi I,Waruiru C,Pasvol G,Warrell D

更新日期：1993-03-01 00:00:00

abstract：:Blood pressure, heart rate and electrocardiographic responses to exercise were compared in a group of 125 subjects with antibodies to Trypanosoma cruzi and in 153 seronegative subjects, randomly selected from persons with no evidence of heart disease in a resting electrocardiogram during a cross-sectional survey among...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Zicker F,Zicker EM,Oliveira JJ,Netto JC,Oliveira RM,Smith PG

更新日期：1990-11-01 00:00:00

abstract：:Manifestations of cysticercosis in 11 children (mean age 9.5 years) are presented. Features of raised intracranial pressure dominated the clinical picture (10 cases), followed by seizures (7 cases). Subretinal cysts occurred in three children. Focal signs were infrequent and often not attributable to anatomical lesion...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kalra V,Paul VK,Marwah RK,Kochhar GS,Bhargava S

更新日期：1987-01-01 00:00:00

abstract：:A purified 200-kDa antigenic fraction from Leishmania donovani axenic amastigotes was evaluated by ELISA for the detection of antibody response in visceral leishmaniasis (VL) patients, post kala-azar dermal leishmaniasis (PKDL) patients and controls, for the diagnosis of visceral leishmaniasis. A positive antibody res...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kaul P,Malla N,Kaur S,Mahajan RC,Ganguly NK

更新日期：2000-03-01 00:00:00

abstract：:Capuchin monkeys were resistant to reinfection with Schistosoma haematobium one year after exposure to 500 cercariae, but worms in these monkeys continued to produce normal numbers of eggs. Monkeys were apparently completely refractory to reinfection when challenged 2-5 years after an initial exposure of 1000 to 2000 ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Cheever AW,Duvall RH,Kuntz RE,Huang TC,Moore JA

更新日期：1988-01-01 00:00:00

abstract：:In a 'blinded' trial (in Sri Lanka, 1996-98) of 47 male asymptomatic microfilaraemic subjects with Wuchereria bancrofti infection, the safety, tolerability and filaricidal efficacy of 3 single-dose combination regimens were compared: albendazole 400 mg with ivermectin 200 micrograms/kg, albendazole 400 mg with diethyl...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ismail MM,Jayakody RL,Weil GJ,Fernando D,De Silva MS,De Silva GA,Balasooriya WK

更新日期：2001-05-01 00:00:00

abstract：:Community treatment with ivermectin was implemented in Opoa, French Polynesia from April 1991 to October 1993. All consenting inhabitants aged 3 years or more were treated with twice-yearly single doses of ivermectin, pregnant women excepted. A dosage of 100 microgram/kg was used for the 3 first treatments and then ab...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Nguyen NL,Moulia-Pelat JP,Cartel JL

更新日期：1996-11-01 00:00:00

abstract：:Pneumocystis carinii occurs in 60-65% of cases of acquired immunodeficiency syndrome (AIDS) in Europe and North America. Its prevalence in Africa is unknown, however, due to a lack of suitable investigative techniques. Initial studies suggest that this parasitic complication may be lower in Africa. An investigation of...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Carme B,Mboussa J,Andzin M,Mbouni E,Mpele P,Datry A

更新日期：1991-01-01 00:00:00

abstract：:Antibody to Ebola virus was found in 14 (1.2%) of 1147 human sera collected in Gabon in 1981-1997. Six seropositive subjects were bled in the northeast in 1991, more than 3 years prior to recognition of the first known outbreak of Ebola haemorrhagic fever (EHF), whilst eight came from the southwest where the disease h...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Lahm SA,Kombila M,Swanepoel R,Barnes RF

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Human T cell lymphotropic virus type 1 (HTLV-1) infection has been associated with recurrent and disseminated strongyloidiasis and adult T cell leukemia/lymphoma (ATLL). METHODS:We compared immunological aspects and markers for ATLL in HTLV-1 patients with or without strongyloidiasis, and evaluated the infl...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Salles F,Bacellar A,Amorim M,Orge G,Sundberg M,Lima M,Santos S,Porto A,Carvalho E

更新日期：2013-08-01 00:00:00