Risk assessment of symptomatic intracerebral hemorrhage after thrombolysis using DWI-ASPECTS.

abstract：BACKGROUND:The method described provides a rational means for determining whether to institute chronic anticoagulation to prevent stroke in patients with chronic atrial fibrillation under a variety of clinical circumstances. SUMMARY OF COMMENT:The concept of expected value is used in conjunction with data from clinica...

journal_title：Stroke

authors： Nadeau SE

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Experimental and clinical data suggest that insonation of echo-contrast agents with high acoustical power produces disintegration of microbubbles, resulting in a pseudo-Doppler phenomenon called stimulated acoustic emission (SAE). The purpose of this study was to investigate whether SAE might be ...

journal_title：Stroke

authors： Pohl C,Tiemann K,Schlosser T,Becher H

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is increasing interest in defining stroke lesion volume thresholds to predict poststroke outcome. However, there is a paucity of data on factors that impact the association between critical infarct thresholds volume and outcome. We sought to determine whether lesion thresholds best predicti...

journal_title：Stroke

authors： Patti J,Helenius J,Puri AS,Henninger N

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to validate the diagnosis of self-reported stroke. METHODS:During 1994-1995, 27 159 people attended a population health survey in the community of Tromso, Norway, a response rate of 77%. A total of 418 attenders reported a history of stroke. In 1997, all individuals wit...

journal_title：Stroke

authors： Engstad T,Bonaa KH,Viitanen M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preclinical data suggest that cell-based therapies have the potential to improve stroke outcomes. METHODS:Eighteen patients with stable, chronic stroke were enrolled in a 2-year, open-label, single-arm study to evaluate the safety and clinical outcomes of surgical transplantation of modified bon...

journal_title：Stroke

authors： Steinberg GK,Kondziolka D,Wechsler LR,Lunsford LD,Coburn ML,Billigen JB,Kim AS,Johnson JN,Bates D,King B,Case C,McGrogan M,Yankee EW,Schwartz NE

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Exogenous delivery of vascular endothelial growth factor gene (VEGF) may provide a useful approach to the treatment of brain ischemia. We investigated the use of a hypoxia-responsive element to control VEGF expression given for neuroprotection. METHODS:Three groups (n=36) of mice received AAVH9-...

journal_title：Stroke

authors： Shen F,Su H,Fan Y,Chen Y,Zhu Y,Liu W,Young WL,Yang GY

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke produces diaschisis in adjacent and connected regions. The sequential changes in diaschisis over time and the relationship of regions of diaschisis to functional cortical areas and regions of poststroke neuroplasticity have not been determined. METHODS:Small cortical strokes were produced...

journal_title：Stroke

authors： Carmichael ST,Tatsukawa K,Katsman D,Tsuyuguchi N,Kornblum HI

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The extent of cardiac investigation required in patients with coexistent symptomatic carotid and cardiac disease is unsettled. This study compared the outlook for patients symptomatic from carotid stenosis with and without a history of symptomatic ischemic heart disease (IHD). METHODS:The risk o...

journal_title：Stroke

authors： Gates PC,Eliasziw M,Algra A,Barnett HJ,Gunton RW,North American Symptomatic Carotid Endarterectomy Trial Group.

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Purinergic nucleoside inosine elicits protection and regeneration during various injuries. The purpose of this study was to examine the protective effects of inosine against cerebral ischemia. METHODS:Adult Sprague-Dawley rats were anesthetized. Inosine, hypoxathine, or vehicle was administered ...

journal_title：Stroke

authors： Shen H,Chen GJ,Harvey BK,Bickford PC,Wang Y

更新日期：2005-03-01 00:00:00

abstract：:This investigation tests the hypothesis that the normal cerebral image obtained non-invasively during continuous inhalation of C15O2 is related to cerebral blood flow. Trace amounts of CO2 labeled with the positron-emitting radionuclide 15O were administered to 4 normal subjects at normo- and hypocapnia and to 2 of th...

journal_title：Stroke

authors： Ackerman RH,Subramanyam R,Correia JA,Alpert NM,Taveras JM

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke-associated immunosuppression is an increasingly recognized factor triggering infections and thus potentially influencing outcome after stroke. Specifically, lymphocytopenia after intracerebral hemorrhage (ICH) has only been addressed in small-sized retrospective studies of mixed intracrani...

journal_title：Stroke

authors： Giede-Jeppe A,Bobinger T,Gerner ST,Madžar D,Sembill J,Lücking H,Kloska SP,Keil T,Kuramatsu JB,Huttner HB

更新日期：2016-05-01 00:00:00

abstract：:Both platelet activating factor and eicosanoids participate in the cerebrovascular response to ischemia. Eicosanoids also modulate cerebrovascular tone under normal physiologic circumstances, but a similar role for platelet activating factor has not been investigated. Therefore, using 16 rats, we studied the effects o...

journal_title：Stroke

authors： Kochanek PM,Melick JA,Schoettle RJ,Magargee MJ,Evans RW,Nemoto EM

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Astrocytes are potent regulators of brain capillary endothelial cell function. Recently, astrocytes were shown to regulate brain capillary endothelial expression of the fibrinolytic enzyme tissue plasminogen activator (tPA) and the anticoagulant thrombomodulin (TM). To study the mechanism of this...

journal_title：Stroke

authors： Tran ND,Correale J,Schreiber SS,Fisher M

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To increase the reliability of 99mTc-hexamethyl propyleneamine oxime (HMPAO) single photon emission computed tomography (SPECT) study in the evaluation of hemodynamic change with balloon test occlusion (BTO) of the internal carotid artery, we attempted to clarify the usefulness of additional moni...

journal_title：Stroke

authors： Kaminogo M,Ochi M,Onizuka M,Takahata H,Shibata S

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We evaluated the impact of admission hyperglycemia (HG) on stroke outcome in relation to the timing of reperfusion in patients treated with tissue plasminogen activator (tPA). METHODS:We studied 138 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with...

journal_title：Stroke

authors： Alvarez-Sabín J,Molina CA,Ribó M,Arenillas JF,Montaner J,Huertas R,Santamarina E,Rubiera M

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Rates of development of de novo intracranial aneurysms and of growth of untreated additional aneurysms are largely unknown. We performed MRA in a large patient cohort with coiled aneurysms at 5-year follow-up. METHODS:In 276 patients with coiled intracranial aneurysms and 5±0.5 years of follow-u...

journal_title：Stroke

authors： Ferns SP,Sprengers ME,van Rooij WJ,van den Berg R,Velthuis BK,de Kort GA,Sluzewski M,van Zwam WH,Rinkel GJ,Majoie CB

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Current US guideline statements regarding primary and secondary cardiovascular risk prediction and prevention use absolute risk estimates to identify patients who are at high risk for vascular disease events and who may benefit from specific preventive interventions. These guidelines do not expli...

journal_title：Stroke

authors： Lackland DT,Elkind MS,D'Agostino R Sr,Dhamoon MS,Goff DC Jr,Higashida RT,McClure LA,Mitchell PH,Sacco RL,Sila CA,Smith SC Jr,Tanne D,Tirschwell DL,Touzé E,Wechsler LR,American Heart Association Stroke Council.,Council on

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined the relationship of carotid artery lesions (CALs), with and without acoustic shadowing (AS), to incident ischemic stroke events in the Atherosclerosis Risk in Communities study cohort. METHODS:The study population consisted of 13 123 men and women aged 45 to 64 years, and free of str...

journal_title：Stroke

authors： Hunt KJ,Evans GW,Folsom AR,Sharrett AR,Chambless LE,Tegeler CH,Heiss G

更新日期：2001-05-01 00:00:00

abstract：:Background and Purpose- We aimed to compare outcomes of ischemic stroke patients with nonvalvular atrial fibrillation between earlier and later initiation of direct oral anticoagulants (DOACs) after stroke onset. Methods- From data for 1192 nonvalvular atrial fibrillation patients with acute ischemic stroke or transie...

journal_title：Stroke

authors： Mizoguchi T,Tanaka K,Toyoda K,Yoshimura S,Itabashi R,Takagi M,Todo K,Shiozawa M,Yagita Y,Yoshimoto T,Terasaki T,Yamagami H,Takizawa S,Inoue M,Kamiyama K,Ihara M,Okada Y,Kitazono T,Koga M,SAMURAI Study Investigators.

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be ...

journal_title：Stroke

authors： McHutchison C,Blair GW,Appleton JP,Chappell FM,Doubal F,Bath PM,Wardlaw JM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to investigate by means of transcranial Doppler (TCD) ultrasonography how many spontaneous reperfusions of the middle cerebral artery (MCA) occurred during the first week after onset of acute ischemic stroke in the carotid territory. METHODS:TCD examination, computed to...

journal_title：Stroke

authors： Zanette EM,Roberti C,Mancini G,Pozzilli C,Bragoni M,Toni D

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to further analyze the temporal patterns of onset of intracerebral hemorrhage (ICH) and to determine whether or not subgroups with specific clinical characteristics exhibit different patterns of onset. METHODS:The daily, weekly, and yearly variations in occurrence o...

journal_title：Stroke

authors： Passero S,Reale F,Ciacci G,Zei E

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although insulin resistance and hyperinsulinemia play a crucial role in the pathogenesis of atherosclerosis, little is known about their roles in ischemic stroke. The purpose of this study was to clarify whether insulin resistance and hyperinsulinemia are causative factors in the pathogenesis of ...

journal_title：Stroke

authors： Shinozaki K,Naritomi H,Shimizu T,Suzuki M,Ikebuchi M,Sawada T,Harano Y

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The risk of stroke and death in patients with atrial fibrillation is strongly associated with age and concomitant comorbidities. The aim of this study was to examine the age dependence of risk factors for stroke and mortality in young patients with atrial fibrillation. METHODS:This study is a po...

journal_title：Stroke

authors： Melgaard L,Rasmussen LH,Skjøth F,Lip GY,Larsen TB

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Persons with early stages of chronic kidney disease, defined by a decreased glomerular filtration rate (GFR), have an increased risk of cardiovascular disease. It is unclear whether decreased GFR is a risk factor for stroke. We assessed the association between GFR and stroke in a prospective popu...

journal_title：Stroke

authors： Bos MJ,Koudstaal PJ,Hofman A,Breteler MM

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There are few studies analyzing stroke in women, taking into account the vascular risk factors, cause of stroke, clinical picture, and outcome. The purpose of this study was to analyze possible sex differences in patients suffering first-ever acute stroke. METHODS:From December 1995 to January 2...

journal_title：Stroke

authors： Roquer J,Campello AR,Gomis M

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been suggested that the interleukin-1A (IL-1A) allele 2 is a risk factor for Alzheimer's disease (AD). Because cerebral amyloid angiopathy-related hemorrhage (CAAH) often coexists with AD, we examined the IL-1A polymorphism in CAAH. METHODS:In a case-control study, patients with pathologi...

journal_title：Stroke

authors： McCarron MO,Stewart J,McCarron P,Love S,Vinters HV,Ironside JW,Mann DM,Graham DI,Nicoll JA

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:lipoprotein(a) [Lp(a)] level is an established risk factor for coronary artery disease and has been implicated in carotid artery disease (CAAD). The relationship between genetic variation in the LPA gene region and CAAD risk remains unknown. METHODS:we genotyped single nucleotide polymorphisms (...

journal_title：Stroke

authors： Ronald J,Rajagopalan R,Cerrato F,Nord AS,Hatsukami T,Kohler T,Marcovina S,Heagerty P,Jarvik GP

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to investigate whether the combination of blood flow measurements in the major cerebral arteries and measurements of cerebral metabolism can provide new insight into the hemodynamic effect of carotid lesions in patients with severe stenosis (> 70% reduction in diameter) of the internal ...

journal_title：Stroke

authors： van der Grond J,Eikelboom BC,Mali WP

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thromboxane prostaglandin receptors have been implicated to be involved in the atherosclerotic process. We assessed whether Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis, as measured by common carotid intima-media thickness and carotid pla...

journal_title：Stroke

authors： Bots ML,Ford I,Lloyd SM,Laurent S,Touboul PJ,Hennerici MG,Prevention of Cerebrovascular and Cardiovascular Events of Ischemic Origin With Terutroban in Patients With a History of Ischemic Stroke or Transient Ischemic Attack Vascular Ultrasou

更新日期：2014-08-01 00:00:00