Abstract:
:Cosmeceuticals are used for nourishing and improving the appearance of the skin and are also documented as effective agents for treating various dermatologic conditions. Cosmeceutical preparations from herbal origin are most popular among consumers because these agents are mostly nontoxic and possess strong antioxidant activity. Because oxidative stress is one of the major mechanisms for skin aging and dermatologic conditions, phytochemicals with proven antioxidant activity, such as silibinin, could be useful for treating many dermatologic conditions as well as skin aging. Silibinin is a flavonolignan compound from Silybum marianum (milk thistle plant) that possesses strong antioxidant activity and also modulates many molecular changes caused by xenobiotics and ultraviolet radiation to protect the skin. This contribution reviews the evidence generated from laboratory studies to support the scientific rationale for the effective use of silibinin in cosmeceutical preparations.
journal_name
Clin Dermatoljournal_title
Clinics in dermatologyauthors
Singh RP,Agarwal Rdoi
10.1016/j.clindermatol.2009.05.012subject
Has Abstractpub_date
2009-09-01 00:00:00pages
479-84issue
5eissn
0738-081Xissn
1879-1131pii
S0738-081X(09)00127-8journal_volume
27pub_type
杂志文章,评审abstract::Although dermatology does not lead the list of specialties most commonly sued for malpractice, anyone who has been the recipient of a malpractice claim is often traumatized both personally and professionally. Every day dermatologists must address various ethical concerns that have legal implications. Herein, we chose ...
journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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abstract::Since the introduction of botulinum toxin (BTX) as a therapeutic tool in the 1970s, the number of uses for this substance has increased exponentially. BTX's mechanism of action involves degrading the SNARE proteins blockading the release of acetylcholine into the neuromuscular junction. In many body systems, decrease ...
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