Abstract：
:About 5% of all cancers worldwide can be attributed to human papillomaviruses (HPVs); namely, six sites are strongly associated with HPV infections: cervix, penis, vulva, vagina, anus, and oropharynx. Nonmelanoma skin cancers (NMSC), basal cell carcinoma (BCC), and squamous cell carcinoma (SCC) are the most common malignancies in Caucasians. In fact, there is an intense connection between sunlight exposure, fair skin, HPV, and development of NMSC. We have conducted a pilot study that included tissue samples from 26 carcinoma patients, of which there were 13 BCC and 13 SCC. HPV detection and typing was done with DNA amplification and sequencing, respectively. In total, 23.1% of SCC samples (3/13) and 7.7% of BCC samples (1/13) were positive for HPV DNA. The importance of understanding all aspects of NMSC carcinogenesis may be to reveal novel therapeutic options or preventive measures for HPV containing NMSC patients.
journal_name
Clin Dermatoljournal_title
Clinics in dermatologyauthors
Drvar DL,Lipozenčić J,Sabol I,Mokos ZB,Ilic I,Grce Mdoi
10.1016/j.clindermatol.2013.08.009subject
Has Abstractpub_date
2014-03-01 00:00:00pages
248-52issue
2eissn
0738-081Xissn
1879-1131pii
S0738-081X(13)00159-4journal_volume
32pub_type
杂志文章abstract：:Pediatric melanoma is rare but increasing in incidence. Because early diagnosis and treatment improves prognosis, clinicians need to include it as a possible diagnosis when evaluating a pigmented lesion in a pediatric patient. Some risk factors for melanoma include xeroderma pigmentosum, giant congenital melanocytic n...
journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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abstract：:Medical clinicians are used to being consulted by patients who want to restore their youthful appearance. Although structural changes to the face and body may be achieved with surgery, for example, face lifts, the impression of youth also relies heavily on young-looking skin. It is desirable to have thicker and tighte...
journal_title：Clinics in dermatology
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abstract：:Oral manifestations of nutritional deficiencies can affect the mucous membranes, teeth, periodontal tissue, salivary glands, and perioral skin. This contribution reviews how the water-soluble vitamins (B(2), B(3), B(6), B(12), C, and folic acid), fat-soluble vitamins (A, D, and E), and minerals (calcium, fluoride, iro...
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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doi：10.1016/j.clindermatol.2007.10.006
更新日期：2008-01-01 00:00:00
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journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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journal_title：Clinics in dermatology
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abstract：:The hereditary disorders of connective tissues (HDCTs) encompass a spectrum of conditions linked pathophysiologically by abnormalities of collagen, fibrillin, and matrix proteins. The clinical picture ranges from morbidity because of musculoskeletal, skin, ocular and visceral pathologies to mortality from acute vascul...
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abstract：:Different physical treatments may be used in acne therapy. The main indications are for treating retentional lesions (open and comedones), inflamed lesions, and scars. ...
journal_title：Clinics in dermatology
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