Phototherapy for atopic dermatitis.

Abstract:

:Phototherapy is a second-line treatment for moderate to severe atopic dermatitis (AD) that effectively decreases cutaneous inflammation with minimal or no systemic side effects. Children in grade school, adolescents, and adults may benefit from phototherapy, when they have chronic AD refractory to first-line topical treatments. This review focuses on six approaches for phototherapy in AD: (1) broadband ultraviolet B (UVB), (2) Goeckerman regimen (coal tar + broadband UVB), (3) narrowband UVB, (4) excimer lasers for targeted areas, (5) combination UVA/UVB, and (6) UVA-1. Phototherapy can be very effective in some individuals, but it is limited by inconvenience and adverse effects, including limited access to in-office treatment, difficulty adhering to thrice-weekly schedule, flaring from excessive heat, and increased risk of skin cancer. Dosing regimen and treatment concerns are reviewed.

journal_name

Clin Dermatol

journal_title

Clinics in dermatology

authors

Rodenbeck DL,Silverberg JI,Silverberg NB

doi

10.1016/j.clindermatol.2016.05.011

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

607-13

issue

5

eissn

0738-081X

issn

1879-1131

pii

S0738-081X(16)30147-X

journal_volume

34

pub_type

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