Sentinel lymph node biopsy.


:The introduction of sentinel lymph node biopsy (SLNB) has been an important development in the management of malignant melanoma. Lymph nodes have long been known to play a key role in melanoma metastasis. The importance of nodal staging accounted for the previous surgical practice of elective lymph node dissection (ELND) even with its controversial impact on final outcomes and associated morbidity. Although this morbidity has been reduced with the ability to identify the SLN, numerous questions have subsequently surfaced with respect to this procedure's utility and therapeutic efficacy. This chapter will focus on the indications for SLNB, as well as the current controversies surrounding this procedure.


Clin Dermatol


Clinics in dermatology


Lee KK,Vetto JT,Mehrany K,Swanson NA




Has Abstract


2004-05-01 00:00:00














  • Therapeutic herbs confirmed by evidence-based medicine.

    abstract::Mucocutaneous diseases and conditions, including aging, are known to be the result of multiple pathophysiologic anomalies induced by various environmental insults. Creating therapeutic products for these multifactorial diseases and conditions is challenging. Although safety testing is not required for cosmetics and co...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Thornfeldt CR

    更新日期:2018-01-01 00:00:00

  • Retirement: An idiosyncratic vade mecum.

    abstract::Many physicians tend to regard their upcoming retirement with great trepidation. They are worried that after years of productive activity they will become useless and lose all their connections with medicine. This essay will try to impress on readers that this way of thinking is absolutely incorrect, and it will provi...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Rudolph RI

    更新日期:2020-01-01 00:00:00

  • Mechanisms of nerve injury in leprosy.

    abstract::All patients with leprosy have some degree of nerve involvement. Perineural inflammation is the histopathologic hallmark of leprosy, and this localization may reflect a vascular route of entry of Mycobacterium leprae into nerves. Once inside nerves, M. leprae are ingested by Schwann cells, with a wide array of consequ...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Scollard DM,Truman RW,Ebenezer GJ

    更新日期:2015-01-01 00:00:00

  • The rash that presents as a red swollen face.

    abstract::A red swollen face can be a skin sign of a potentially life-threatening condition. We present in detail the main clinical presentations, diagnostic tests, and management of some of the most severe conditions that can frequently present as a red and swollen face: acute or recurrent angioedema, mast cell-driven or brady...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Batista M,Gonçalo M

    更新日期:2020-01-01 00:00:00

  • Feedback practices in dermatology residency programs: building a culture for millennials.

    abstract::Corporate studies have consistently shown that millennials prefer more frequent and detailed feedback in the workplace. With most dermatology residents fitting the description of a millennial, we sought to study their preferences in feedback and then compare this to current feedback practices and cultures. Our study s...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Wang JV,O'Connor M,McGuinn K,Albornoz CA,Keller M

    更新日期:2019-01-01 00:00:00

  • Teledermatology: Kids are not just little people.

    abstract::Teledermatology has emerged as a promising solution for pediatric and adult patients accessing dermatologic care in a health care environment fraught with barriers to access. Teledermatology has been extensively evaluated in terms of diagnostic accuracy, clinical outcomes, patient and provider satisfaction, and costs,...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Naka F,Makkar H,Lu J

    更新日期:2017-01-01 00:00:00

  • Chronic immunosuppression in the mature patient.

    abstract::In the ever-aging population of the world, the field of geriatrics continues to grow in importance. As human beings age, the skin undergoes a unique array of changes that predispose it to a specific set of dermatoses, infections, and neoplasms. Some of these physiologic alterations are comparable to the changes that h...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Sergeyenko AM,Rosenfeld DJ,Tsoukas MM

    更新日期:2018-01-01 00:00:00

  • Phototherapy for atopic dermatitis.

    abstract::Phototherapy is a second-line treatment for moderate to severe atopic dermatitis (AD) that effectively decreases cutaneous inflammation with minimal or no systemic side effects. Children in grade school, adolescents, and adults may benefit from phototherapy, when they have chronic AD refractory to first-line topical t...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Rodenbeck DL,Silverberg JI,Silverberg NB

    更新日期:2016-09-01 00:00:00

  • Gene therapy approaches for epidermolysis bullosa.

    abstract::Human epidermis consists of a stratified epithelium mainly composed of keratinocytes and relies on a stem cell compartment to undergo constant regeneration. Genetic mutations affecting the capacity of basal keratinocytes to adhere firmly to the epidermal basement membrane lead to severe, and very often lethal, blister...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Ferrari S,Pellegrini G,Mavilio F,De Luca M

    更新日期:2005-07-01 00:00:00

  • Cutaneous zygomycosis.

    abstract::Cutaneous zygomycosis is a fungal infection caused by zygomycetes that affects the skin. It occurs in uncontrolled diabetic patients and immunosuppressed individuals. It has 2 clinical forms: primary cutaneous zygomycosis and secondary cutaneous zygomycosis. The first is characterized by necrotic lesions and the fungu...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Bonifaz A,Vázquez-González D,Tirado-Sánchez A,Ponce-Olivera RM

    更新日期:2012-07-01 00:00:00

  • Robert Koch (1843-1910) and dermatology on his 171st birthday.

    abstract::Robert Koch (1843-1910) received the Nobel Prize in Medicine in 1905 for his studies of tuberculosis. He contributed significantly to microbiology, isolating also cholera and anthrax pathogens, and introducing several postulates in this field. In addition, he developed staining methods, as well as culturing and micros...

    journal_title:Clinics in dermatology

    pub_type: 传,历史文章,杂志文章


    authors: Grzybowski A,Pietrzak K

    更新日期:2014-05-01 00:00:00

  • Psoriasis: Psychosomatic, somatopsychic, or both?

    abstract::Psoriasis is a chronic inflammatory disorder characterized by substantial psychiatric comorbidity. Historically, anecdotal observations have suggested that psychosocial distress can trigger flares of psoriasis, but over the past several decades, high-quality data from experimental studies support the assertion that st...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Kwon CW,Fried RG,Nousari Y,Ritchlin C,Tausk F

    更新日期:2018-01-01 00:00:00

  • Autoinflammatory syndromes for the dermatologist.

    abstract::While autoimmunity as cause of disease is well-established, other categories of immune-mediated diseases that are not produced by targeting of self-antigens by antibodies is in the process of being described. These so-called autoinflammatory diseases arise when an inappropriate activation of antigen-independent mechan...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Dávila-Seijo P,Hernández-Martín A,Torrelo A

    更新日期:2014-07-01 00:00:00

  • Chronic urticaria as a systemic disease.

    abstract::Urticaria is one of the most common diseases seen in everyday dermatologic practice, characterized by the development of wheals, angioedema, or both. While acute urticaria is mostly related to allergic or pseudoallergic reaction to food, drugs, or infections, chronic urticaria is a more complex disease with different ...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Darlenski R,Kazandjieva J,Zuberbier T,Tsankov N

    更新日期:2014-05-01 00:00:00

  • Thermage: the nonablative radiofrequency for rejuvenation.

    abstract::Thermage is a noninvasive nonablative device that uses monopolar radiofrequency energy to bulk heat underlying skin while protecting the epidermis to produce skin tightening. It is used for the treatment of rhytids on the face including the periorbital region and lower face, and more recently, for off-face application...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Sukal SA,Geronemus RG

    更新日期:2008-11-01 00:00:00

  • Dermatologic manifestations of parathyroid-related disorders.

    abstract::Dermatologic manifestations of parathyroid-related disorders, although rare in sporadic cases, are not uncommon in familial syndromes. Patients with familial hyperparathyroidism have several types of skin lesions. In multiple endocrine neoplasia 1, patients commonly have angiofibromas (85%) and collagenomas (70%), les...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Fuleihan Gel-H,Rubeiz N

    更新日期:2006-07-01 00:00:00

  • Morphologic grading and treatment of facial actinic keratosis.

    abstract::Actinic keratoses (AKs) represent the earliest stage in the development of squamous cell carcinoma (SCC) and represent important biomarkers for individuals at risk for development of invasive SCC. Based on clinical morphology, AK can be subdivided into three different grades, which correspond to specific dermatoscopic...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Zalaudek I,Piana S,Moscarella E,Longo C,Zendri E,Castagnetti F,Pellacani G,Lallas A,Argenziano G

    更新日期:2014-01-01 00:00:00

  • Sjögren's syndrome in dermatology.

    abstract::Sjogren's Syndrome (SS) is a systemic autoimmune disease characterized by dry eyes (keratoconjunctivis sicca) and dry mouth (xerostomia). To fulfill diagnostic criteria, patients must have objective signs of dryness on examination and laboratory confirmation of an autoimmune process as evidenced by a positive autoanti...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Fox RI,Liu AY

    更新日期:2006-09-01 00:00:00

  • The Ubangi misnomer.

    abstract::Lip plates are a form of body modification practiced today by several tribes in Africa and Amazonia. In 1930, the American people were introduced to lip plates in a most spectacular fashion, when the Ringling Bros. and Barnum & Bailey Circus brought in 13 Congolese natives to star as the newest attraction in their sid...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Hoenig LJ

    更新日期:2020-01-01 00:00:00

  • Inflammatory ulcers.

    abstract::Skin ulcerations may develop as a manifestation of a variety of different diseases or may result from some nondisease phenomena. Inflammatory ulcers refer specifically to those ulcerations in which inflammation is the primary pathologic process resulting in lesion formation; that is, inflammation is the cause rather t...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Hoffman MD

    更新日期:2007-01-01 00:00:00

  • An open-label, single-center pilot study to determine the antifungal activity of a new nonsteroidal cream (Promiseb Topical Cream) after 7 days of use in healthy volunteers.

    abstract::Topical corticosteroids are effective for the treatment of seborrheic dermatitis. The duration of treatment with mid- to high-potency formulations is limited by the well-known side effects associated with their long-term use; further, topical corticosteroids treat only the inflammation associated with the disease. Thi...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Kircik L

    更新日期:2009-11-01 00:00:00

  • Alterations of skin innate immunity in lymphedematous limbs: Correlations with opportunistic diseases.

    abstract::Lymphedematous areas are sites of regional immune destabilization depicting a typical example of an immunocompromised cutaneous district (ICD). This study evaluates the expression of some components of the skin innate immunity on lymphedematous limbs with the aim to clarify some facets of the ICD. Patients selected un...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Baroni A,Buommino E,Piccolo V,Chessa MA,Russo T,Cozza V,Ruocco V

    更新日期:2014-09-01 00:00:00

  • Jan Mikulicz-Radecki (1850-1905): his impact on modern medicine.

    abstract::Abstract Jan Mikulicz-Radecki (1850-1905) was the cofounder of modern surgery, aseptic techniques,and the inventor of gastroscopy, but his professional accomplishments go far beyond the field of surgical treatment. Various medical achievements are named in his honor, including the name of the cells that he discovered ...

    journal_title:Clinics in dermatology

    pub_type: 传,历史文章,杂志文章


    authors: Grzybowski A,Sak J

    更新日期:2012-01-01 00:00:00

  • Mosaicism in genodermatoses.

    abstract::Genodermatoses are inherited disorders presenting with cutaneous manifestations with or without the involvement of other systems. The majority of these disorders, particularly in cases that present with a cutaneous patterning, may be explained in the context of genetic mosaicism. Despite the barriers to the genetic an...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Cheraghlou S,Lim Y,Choate KA

    更新日期:2020-01-01 00:00:00

  • No more pens: what the 2009 Pharmaceutical Research and Manufacturer's Association code changes really mean.

    abstract::In 2002, new guidelines for interactions with the pharmaceutical industry and physicians were published as an official code of conduct. Adherence to the guidelines was voluntary, and there were no provisions for discipline to companies who did not subscribe to the code or who subscribed but did not comply. Many of the...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Meffert JJ

    更新日期:2009-07-01 00:00:00

  • Injectable neurotoxins and fillers: there is no free lunch.

    abstract::Injection of neurotoxins and filling agents for the treatment of facial aesthetics has increased dramatically during the past few decades due to an increased interest in noninvasive aesthetic improvements. An aging but still youth-oriented population expects effective treatments with minimal recovery time and limited ...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Emer J,Waldorf H

    更新日期:2011-11-01 00:00:00

  • Ocular changes induced by drugs commonly used in dermatology.

    abstract::The use of many drugs in dermatologic diseases may cause ocular side effects. Some may regress after discontinuation of the therapy, but others persist or progress even after the cessation of treatment. This review presents four groups of commonly prescribed drugs-antimalarial medicines, glucocorticoids, retinoids, an...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Turno-Kręcicka A,Grzybowski A,Misiuk-Hojło M,Patryn E,Czajor K,Nita M

    更新日期:2016-03-01 00:00:00

  • Intrahepatic cholestasis of pregnancy: Recent advances.

    abstract::Intrahepatic cholestasis of pregnancy, also known as obstetric cholestasis, is a pruritic condition of pregnancy characterized by an underlying elevation in circulating bile acids and liver derangement, and associated with adverse fetal outcomes, such as preterm labor and stillbirth. Limited understanding of the under...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Ovadia C,Williamson C

    更新日期:2016-05-01 00:00:00

  • Perfluoropolyether phosphate: a non-irritating acidic agent of cosmeceutical use.

    abstract::Formulating at acidic pH is a route to improve the chemical or biological stability and the performances of cosmeceuticals. Unfortunately, its potential is limited by the poor differentiation of available acidic agents, and by the risk of skin irritation. Recently, a perfluoropolyether phosphate was proposed to formul...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Pantini G

    更新日期:2008-07-01 00:00:00

  • Joint hypermobility and skin elasticity: the hereditary disorders of connective tissue.

    abstract::The hereditary disorders of connective tissues (HDCTs) encompass a spectrum of conditions linked pathophysiologically by abnormalities of collagen, fibrillin, and matrix proteins. The clinical picture ranges from morbidity because of musculoskeletal, skin, ocular and visceral pathologies to mortality from acute vascul...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Hakim AJ,Sahota A

    更新日期:2006-11-01 00:00:00