Abstract:
:Heinrich Koebner (1838-1904) presented in a meeting in 1872 and reported in 1877 the emergence of psoriatic lesions following trauma to healthy skin areas of patients with psoriasis. Since then, the Koebner phenomenon has been the subject of research, as it offers a unique opportunity in the investigation of the disease, especially in experimental studies, when this dermatosis may be observed in all its phases. Establishing the differences between Koebner, Wolf, Renbök, reverse Koebner, pseudo-Koebner phenomena, and pathergy is sometimes unclear. We review the various aspects of the Koebner phenomenon's clinical description and presentation, pathophysiology, histopathology, reverse phenomenon, therapeutic treatments, and prevention.
journal_name
Clin Dermatoljournal_title
Clinics in dermatologyauthors
Camargo CM,Brotas AM,Ramos-e-Silva M,Carneiro Sdoi
10.1016/j.clindermatol.2013.05.012subject
Has Abstractpub_date
2013-11-01 00:00:00pages
741-9issue
6eissn
0738-081Xissn
1879-1131pii
S0738-081X(13)00079-5journal_volume
31pub_type
杂志文章abstract::Alopecia is a skin condition of great social and psychologic impact. Primary alopecia originates from the hair follicles and usually does not have systemic manifestations; however, secondary alopecia can affect the hair follicles in the setting of systemic diseases, medications, and external trauma. Connective tissue ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2019.07.026
更新日期:2019-01-01 00:00:00
abstract::Somatic symptom disorder (SSD) is defined by the prominence of somatic symptoms associated with abnormal thoughts, feelings, and behaviors related to the symptoms, resulting in significant distress and impairment. Individuals with these disorders are more commonly encountered in primary care and other medical settings...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2017.01.010
更新日期:2017-01-01 00:00:00
abstract::From the Eskimo in Greenland to the tribes in Polynesia-the whole world knows the art of tattoo. Despite their wide popularity the relation between the skin diseases and the tattooed pictures aren't studied in depth. With the appearance of professional tattoo studios, the risk of infectious complications was reduced. ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2007.05.012
更新日期:2007-07-01 00:00:00
abstract::The development of immunotherapy has led to a paradigm shift in the treatment of both solid and hematologic malignancies. As immunomodulatory therapies are employed with increasing frequency, a greater number of immune-related adverse reactions are being reported, and the majority of these involve the skin. As a resul...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2020.06.011
更新日期:2020-01-01 00:00:00
abstract::Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are uncommon but extremely serious and often life-threatening mucocutaneous reactions characterized by extensive epithelial sloughing and systemic symptoms. There is no effective evidence-based treatment for severe cutaneous adverse reactions (SCAR) t...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2009.06.020
更新日期:2010-05-01 00:00:00
abstract::Cutaneous zygomycosis is a fungal infection caused by zygomycetes that affects the skin. It occurs in uncontrolled diabetic patients and immunosuppressed individuals. It has 2 clinical forms: primary cutaneous zygomycosis and secondary cutaneous zygomycosis. The first is characterized by necrotic lesions and the fungu...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2011.09.013
更新日期:2012-07-01 00:00:00
abstract::Patient education programs are beneficial in the treatment of chronic diseases. In Germany, France, and other countries worldwide, educating children, adolescents, and adults plus the parents of children with atopic dermatitis (AD) leads to better coping with the skin disease, as well as to a reduction in the severity...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2018.05.006
更新日期:2018-01-01 00:00:00
abstract::The introduction of sentinel lymph node biopsy (SLNB) has been an important development in the management of malignant melanoma. Lymph nodes have long been known to play a key role in melanoma metastasis. The importance of nodal staging accounted for the previous surgical practice of elective lymph node dissection (EL...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2003.12.011
更新日期:2004-05-01 00:00:00
abstract::Tattoos have gained worldwide popularity in recent years, and vaccinations are universal preventive measures designed to minimize morbidity associated with specific pathogens. Both dermal tattoos and vaccine injections may alter local immune responses, creating an immunocompromised district on or near the site of plac...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2014.04.016
更新日期:2014-09-01 00:00:00
abstract::The relationship between pregnancy and diseases of the elastic fibers, such as pseudoxanthoma elasticum, cutis laxa, and anetoderma, is discussed in this article. Dermatologists and other physicians must be aware that these problems may be present in pregnant women and must also know how to counsel those who suffer fr...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2005.10.005
更新日期:2006-03-01 00:00:00
abstract::In the ever-aging population of the world, the field of geriatrics continues to grow in importance. As human beings age, the skin undergoes a unique array of changes that predispose it to a specific set of dermatoses, infections, and neoplasms. Some of these physiologic alterations are comparable to the changes that h...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2017.10.017
更新日期:2018-01-01 00:00:00
abstract::Optimal management of full-thickness wounds requires a thorough knowledge of wound-healing principles and practices. In the absence of underlying disease, almost every full-thickness wound will heal with minimal intervention; however, the process can be enhanced by judicious wound management. The first clinical decisi...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2006.10.001
更新日期:2007-01-01 00:00:00
abstract::There are numerous barriers to conducting clinical research in pregnancy, including ethical considerations, logistical difficulties, and federal regulations. Due to these challenges, there is a paucity of data on the safe and appropriate use of dermatologic therapies in pregnancy, even for easily accessed over-the-cou...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2016.02.014
更新日期:2016-05-01 00:00:00
abstract::Skin phototyping refers to a skin classification scheme based on how the skin responds to sun exposure. The Fitzpatrick classification is the most widely accepted method of skin phototyping, based on a person's tendency to sunburn and ability to tan. Apart from estimating the initial therapeutic dose of UV light, skin...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2019.07.010
更新日期:2019-01-01 00:00:00
abstract::This contribution, which is somewhat of a departure from the usual format, will focus on dermatologic conditions that are consequences of the patients' choices of employment, hobby, or even other forms of recreation. Most of the cutaneous changes involve the hands and feet, and each is labeled according to the anatomi...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2016.09.002
更新日期:2017-01-01 00:00:00
abstract::Psoriasis is a chronic inflammatory disorder characterized by substantial psychiatric comorbidity. Historically, anecdotal observations have suggested that psychosocial distress can trigger flares of psoriasis, but over the past several decades, high-quality data from experimental studies support the assertion that st...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2018.08.009
更新日期:2018-01-01 00:00:00
abstract::The presence of a true melanoma epidemic has been a controversial topic for the past decade. A dramatic increase in the incidence of cutaneous malignant melanoma in developed countries is well documented, but mortality rates have not risen as rapidly. This has generated much discussion about whether there is a true in...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2009.06.021
更新日期:2010-05-01 00:00:00
abstract::Hailey-Hailey disease, also called benign familial pemphigus, is a late-onset blistering disorder that affects the flexures. There are typically painful erosions and cracks in affected areas. Lesions generally begin between 20 and 40 years of age. In two third of all cases, positive family history is detected. In path...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2015.04.006
更新日期:2015-07-01 00:00:00
abstract::There is a high demand for facial aesthetic enhancement, and the periorbital region is one of the first areas to show signs of aging. Many nonsurgical therapies exist to tackle these problems. These therapies are becoming more efficacious while reducing postprocedural recovery time. The goal is to restore the natural ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2014.10.012
更新日期:2015-03-01 00:00:00
abstract::Nail surgery is a special branch of hand and dermatologic surgery. It is not widely performed, and many physicians do not feel at ease to perform it. The objective of this contribution is to give a short overview of the most important surgical procedures in clinical practice. References from the literature and the aut...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2013.06.012
更新日期:2013-09-01 00:00:00
abstract::With a prevalence of 2% to 3%, psoriasis is a very common chronic disease worldwide and generates therapy costs and continuing cost for health insurance and patients and their families. Cost-political changes in health care and the ever increasing health-economic demands in all areas of the health system make it neces...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2007.10.024
更新日期:2008-09-01 00:00:00
abstract::A new or changing melanocytic nevus in a child or adolescent often leads to concern in parents and physicians. To avoid undue alarm and unnecessary procedures, dermatologists should be aware of the natural history and clinical spectrum of nevi in pediatric patients, as well as findings that are potentially worrisome i...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2014.12.015
更新日期:2015-05-01 00:00:00
abstract::Obesity is associated with a number of dermatoses. It affects cutaneous sensation, temperature regulation, foot shape, and vasculature. Acanthosis nigricans is the most common dermatological manifestation of obesity. Skin tags are more commonly associated with diabetes than with obesity. Obesity increases the incidenc...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2004.01.001
更新日期:2004-07-01 00:00:00
abstract::All patients with leprosy have some degree of nerve involvement. Perineural inflammation is the histopathologic hallmark of leprosy, and this localization may reflect a vascular route of entry of Mycobacterium leprae into nerves. Once inside nerves, M. leprae are ingested by Schwann cells, with a wide array of consequ...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2014.07.008
更新日期:2015-01-01 00:00:00
abstract::Shortly after syphilis appeared in Europe at the time of Columbus' voyage to the New World, the big pox, as it was often known, became a serious issue in Russia for diagnosis, treatment, and prevention. Members of the Russian royal family were made aware of the disease from adolescence onward. Czar Peter the Great had...
journal_title:Clinics in dermatology
pub_type: 历史文章,杂志文章
doi:10.1016/j.clindermatol.2019.09.002
更新日期:2020-01-01 00:00:00
abstract::The recognition of botulinum toxin as a therapeutic tool has revolutionized the approach to facial esthetics. In the 1970s, Dr. Alan B. Scott pioneered the use of botulinum toxin type A (BTX-A) for strabismus. This discovery led to further studies examining other clinical applications of BTX-A and, more recently, botu...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2003.11.009
更新日期:2003-11-01 00:00:00
abstract::Topical corticosteroids are effective for the treatment of seborrheic dermatitis. The duration of treatment with mid- to high-potency formulations is limited by the well-known side effects associated with their long-term use; further, topical corticosteroids treat only the inflammation associated with the disease. Thi...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2009.09.004
更新日期:2009-11-01 00:00:00
abstract::About 5% of all cancers worldwide can be attributed to human papillomaviruses (HPVs); namely, six sites are strongly associated with HPV infections: cervix, penis, vulva, vagina, anus, and oropharynx. Nonmelanoma skin cancers (NMSC), basal cell carcinoma (BCC), and squamous cell carcinoma (SCC) are the most common mal...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2013.08.009
更新日期:2014-03-01 00:00:00
abstract::José Maria Vargas, (1786-1854), who was born on March 10, 1796, graduated with a Doctor of Medicine degree from the Central University of Venezuela in 1808. He was subsequently imprisoned in 1813 by the Spanish authorities for his independence activities. When finally freed, he traveled to Edinburgh for postgraduate m...
journal_title:Clinics in dermatology
pub_type: 传,历史文章,杂志文章
doi:10.1016/j.clindermatol.2019.07.004
更新日期:2020-01-01 00:00:00
abstract::Abstract Jan Mikulicz-Radecki (1850-1905) was the cofounder of modern surgery, aseptic techniques,and the inventor of gastroscopy, but his professional accomplishments go far beyond the field of surgical treatment. Various medical achievements are named in his honor, including the name of the cells that he discovered ...
journal_title:Clinics in dermatology
pub_type: 传,历史文章,杂志文章
doi:10.1016/j.clindermatol.2011.05.004
更新日期:2012-01-01 00:00:00