Abstract:
:There are numerous barriers to conducting clinical research in pregnancy, including ethical considerations, logistical difficulties, and federal regulations. Due to these challenges, there is a paucity of data on the safe and appropriate use of dermatologic therapies in pregnancy, even for easily accessed over-the-counter topical products, as well as for commonly prescribed medications. Given the lack of human safety data, the Food and Drug Administration pregnancy labeling system previously placed a high priority on animal data but was recently revised to highlight human data and pregnancy registries. The latter can provide prospective observational data on medication use in pregnant women, while avoiding many of the pitfalls of conducting clinical trials in this population; nevertheless, registry enrollment for dermatologic drugs remains low. Dermatologists must increase awareness of pregnancy registries and encourage patient enrollment to close this knowledge gap.
journal_name
Clin Dermatoljournal_title
Clinics in dermatologyauthors
Hartman RI,Kimball ABdoi
10.1016/j.clindermatol.2016.02.014subject
Has Abstractpub_date
2016-05-01 00:00:00pages
410-5issue
3eissn
0738-081Xissn
1879-1131pii
S0738-081X(16)30029-3journal_volume
34pub_type
杂志文章abstract::Although dermatology does not lead the list of specialties most commonly sued for malpractice, anyone who has been the recipient of a malpractice claim is often traumatized both personally and professionally. Every day dermatologists must address various ethical concerns that have legal implications. Herein, we chose ...
journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
pub_type: 杂志文章
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2009.02.005
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journal_title:Clinics in dermatology
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