Sarcoidosis and malignancy.


:Malignancy in patients with sarcoidosis occurs in 3 settings. The first setting relates to patients with hematologic malignancies. It includes the sarcoidosis-lymphoma syndrome, which refers to the development of lymphoma at least 1 to 2 years after the diagnosis of sarcoidosis. It also includes patients with sarcoidosis who develop other hematologic malignancies. In addition, this subset of individuals includes patients with cancer and hematologic malignancies who subsequently develop sarcoidosis. The second setting consists of patients with sarcoidosis who develop solid tumors and oncologic patients in whom sarcoidosis subsequently appears; in addition to melanoma and nonmelanoma skin cancer, the neoplasms most commonly associated involve the cervix, liver, lung, testicles, and uterus. The third setting of malignancy-related sarcoidosis occurs when sarcoidosis presents as a paraneoplastic syndrome for the associated cancer, specifically when the discovery of cancer is concurrent with or within 1 year of the diagnosis of sarcoidosis or vis-a-vis. Antineoplastic treatment of either the hematologic malignancy or the solid tumor has also been observed to either induce the initial onset or flare the activity of sarcoidosis. Malignancy can also be associated with the occurrence of sarcoid reactions that typically are restricted to the regional lymph nodes or the visceral organ of tumor origin; rarely, the sarcoid reaction can also be observed in the skin or is only limited to the skin.


Clin Dermatol


Clinics in dermatology


Cohen PR,Kurzrock R




Has Abstract


2007-05-01 00:00:00














  • Personality disorders and the "difficult" dermatology patient: Maximizing patient satisfaction.

    abstract::Personality disorders (PDs) are stable and enduring patterns of thought, feeling, and behavior that deviate from one's cultural norms and cause impairment in functionality. Patients with PDs are commonly encountered in the dermatologic setting and can be perceived by providers as "difficult." Given that PDs are chroni...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Nakamura M,Koo J

    更新日期:2017-01-01 00:00:00

  • Retirement: An idiosyncratic vade mecum.

    abstract::Many physicians tend to regard their upcoming retirement with great trepidation. They are worried that after years of productive activity they will become useless and lose all their connections with medicine. This essay will try to impress on readers that this way of thinking is absolutely incorrect, and it will provi...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Rudolph RI

    更新日期:2020-01-01 00:00:00

  • Treatment of alopecia areata with squaric acid dibutylester.

    abstract::Squaric acid dibutylester is a topical sensitizing agent utilized for the treatment of alopecia areata. The mechanism of action is not fully understood, but is believed to redirect the inflammatory response by invoking allergic contact dermatitis. Several studies have compared the efficacy of squaric acid dibutylester...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Hill ND,Bunata K,Hebert AA

    更新日期:2015-05-01 00:00:00

  • Diseases of the tongue.

    abstract::The tongue is a complex organ involved in speech and expression as well as in gustation, mastication, and deglutition. The oral cavity, along with the tongue, are sites of neoplasms, reactive processes, and infections, and may be a harbinger of systemic diseases. This review includes both common and rare diseases that...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Mangold AR,Torgerson RR,Rogers RS 3rd

    更新日期:2016-07-01 00:00:00

  • Skin bank organization.

    abstract::Skin allografts were first used at the end of the last century by Girdner [Girdner JH. Skin grafting with graft taken from the dead subject. Med Rec (NY) 1881;20:119-20]; however, routine storage of human tissue developed only in the 1930s to 1940s [Webster JP. Refrigerated skin grafts. Ann Surg 1944;120:431-49] when ...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Pianigiani E,Ierardi F,Cherubini Di Simplicio F,Andreassi A

    更新日期:2005-07-01 00:00:00

  • Economic considerations in psoriasis management.

    abstract::With a prevalence of 2% to 3%, psoriasis is a very common chronic disease worldwide and generates therapy costs and continuing cost for health insurance and patients and their families. Cost-political changes in health care and the ever increasing health-economic demands in all areas of the health system make it neces...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Radtke MA,Augustin M

    更新日期:2008-09-01 00:00:00

  • Alterations of skin innate immunity in lymphedematous limbs: Correlations with opportunistic diseases.

    abstract::Lymphedematous areas are sites of regional immune destabilization depicting a typical example of an immunocompromised cutaneous district (ICD). This study evaluates the expression of some components of the skin innate immunity on lymphedematous limbs with the aim to clarify some facets of the ICD. Patients selected un...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Baroni A,Buommino E,Piccolo V,Chessa MA,Russo T,Cozza V,Ruocco V

    更新日期:2014-09-01 00:00:00

  • Complications of decorative tattoo.

    abstract::Decorative tattoo is a popular practice that is generally safe when performed in the professional setting but can be associated with a variety of inflammatory, infectious, and neoplastic complications, risks that may be increased with current trends in home tattooing. Modern tattoo inks contain azo dyes and are often ...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Shinohara MM

    更新日期:2016-03-01 00:00:00

  • Metastatic melanoma in the older patient: special considerations.

    abstract::Cancer is a disease of older age where genomic instability, impaired DNA repair, and weakened immune surveillance against cancer are recognized to play a causative role. Because the incidence of melanoma is increasing at a very fast pace in the elderly and there is a rapid expansion of the aging population, a large nu...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Hegde UP,Grant-Kels JM

    更新日期:2013-05-01 00:00:00

  • Perfluoropolyether phosphate: a non-irritating acidic agent of cosmeceutical use.

    abstract::Formulating at acidic pH is a route to improve the chemical or biological stability and the performances of cosmeceuticals. Unfortunately, its potential is limited by the poor differentiation of available acidic agents, and by the risk of skin irritation. Recently, a perfluoropolyether phosphate was proposed to formul...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Pantini G

    更新日期:2008-07-01 00:00:00

  • The modern paradigm of phototherapy.

    abstract::The recognition of medical benefits obtained with suberythemogenic doses of natural sunlight extends back centuries. Modern medical application of phototherapy has been in place for over 100 years. It is the nature of scientific discovery to depend upon the use of new investigational methods or new devices to gain a b...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Zanolli M

    更新日期:2003-09-01 00:00:00

  • Dermatologic manifestations of parathyroid-related disorders.

    abstract::Dermatologic manifestations of parathyroid-related disorders, although rare in sporadic cases, are not uncommon in familial syndromes. Patients with familial hyperparathyroidism have several types of skin lesions. In multiple endocrine neoplasia 1, patients commonly have angiofibromas (85%) and collagenomas (70%), les...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Fuleihan Gel-H,Rubeiz N

    更新日期:2006-07-01 00:00:00

  • Mechanisms of nerve injury in leprosy.

    abstract::All patients with leprosy have some degree of nerve involvement. Perineural inflammation is the histopathologic hallmark of leprosy, and this localization may reflect a vascular route of entry of Mycobacterium leprae into nerves. Once inside nerves, M. leprae are ingested by Schwann cells, with a wide array of consequ...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Scollard DM,Truman RW,Ebenezer GJ

    更新日期:2015-01-01 00:00:00

  • Psoriasis: epidemiology.

    abstract::Psoriasis is a chronic, inflammatory and hyperproliferative skin disease with a genetic basis. While epidermal hyperplasia and altered keratinocyte differentiation are prominent features, considerable evidence indicates that psoriasis is immunologically mediated. Recently, the identification of HLA-Cw6 as the disease ...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Gudjonsson JE,Elder JT

    更新日期:2007-11-01 00:00:00

  • Systemic therapies in atopic dermatitis: The pipeline.

    abstract::Atopic dermatitis (AD), the most prevalent inflammatory skin disease, is characterized by robust T-cell activation. The disease has several subtypes, all having a common T helper type 2 (Th2)/Th22 polarization, but it also displays differential immune skewing, such as increased Th17/interleukin 23 skewing in the skin ...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Renert-Yuval Y,Guttman-Yassky E

    更新日期:2017-01-01 00:00:00

  • Systemic drug reactions with skin involvement: Stevens-Johnson syndrome, toxic epidermal necrolysis, and DRESS.

    abstract::Skin is often affected in adverse drug reactions. Although the majority of cutaneous adverse drug reactions are benign and self-limiting, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug rash with eosinophilia and systemic symptoms (DRESS), affecting multiple organs and systems, are potential...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Darlenski R,Kazandjieva J,Tsankov N

    更新日期:2015-09-01 00:00:00

  • The skin in the gym: a comprehensive review of the cutaneous manifestations of community-acquired methicillin-resistant Staphylococcus aureus infection in athletes.

    abstract::Community-acquired methicillin-resistant Staphylococcus aureus (CAMRSA) infection is currently a problem of epidemic proportion. Athletes represent a specific group of individuals who are at increased risk to develop CAMRSA skin infections. In this article, the previously published reports of cutaneous CAMRSA infectio...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Cohen PR

    更新日期:2008-01-01 00:00:00

  • Scleroderma: nomenclature, etiology, pathogenesis, prognosis, and treatments: facts and controversies.

    abstract::Scleroderma refers to a heterogeneous group of autoimmune fibrosing disorders. The nomenclature of scleroderma has changed dramatically in recent years, with morphea (localized scleroderma), limited cutaneous systemic sclerosis, diffuse cutaneous systemic sclerosis, and systemic sclerosis sine scleroderma encompassing...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Fett N

    更新日期:2013-07-01 00:00:00

  • Intrahepatic cholestasis of pregnancy: Recent advances.

    abstract::Intrahepatic cholestasis of pregnancy, also known as obstetric cholestasis, is a pruritic condition of pregnancy characterized by an underlying elevation in circulating bile acids and liver derangement, and associated with adverse fetal outcomes, such as preterm labor and stillbirth. Limited understanding of the under...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Ovadia C,Williamson C

    更新日期:2016-05-01 00:00:00

  • Robert Koch (1843-1910) and dermatology on his 171st birthday.

    abstract::Robert Koch (1843-1910) received the Nobel Prize in Medicine in 1905 for his studies of tuberculosis. He contributed significantly to microbiology, isolating also cholera and anthrax pathogens, and introducing several postulates in this field. In addition, he developed staining methods, as well as culturing and micros...

    journal_title:Clinics in dermatology

    pub_type: 传,历史文章,杂志文章


    authors: Grzybowski A,Pietrzak K

    更新日期:2014-05-01 00:00:00

  • Acne: physical treatment.

    abstract::Different physical treatments may be used in acne therapy. The main indications are for treating retentional lesions (open and comedones), inflamed lesions, and scars. ...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Dreno B

    更新日期:2004-09-01 00:00:00

  • Nutrition and oral mucosal diseases.

    abstract::Oral manifestations of nutritional deficiencies can affect the mucous membranes, teeth, periodontal tissue, salivary glands, and perioral skin. This contribution reviews how the water-soluble vitamins (B(2), B(3), B(6), B(12), C, and folic acid), fat-soluble vitamins (A, D, and E), and minerals (calcium, fluoride, iro...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Thomas DM,Mirowski GW

    更新日期:2010-07-01 00:00:00

  • Occupational acral dermatitis and where the twain shall meet.

    abstract::This contribution, which is somewhat of a departure from the usual format, will focus on dermatologic conditions that are consequences of the patients' choices of employment, hobby, or even other forms of recreation. Most of the cutaneous changes involve the hands and feet, and each is labeled according to the anatomi...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Wolf R,Parish LC,Tüzün Y

    更新日期:2017-01-01 00:00:00

  • Cosmeceuticals and silibinin.

    abstract::Cosmeceuticals are used for nourishing and improving the appearance of the skin and are also documented as effective agents for treating various dermatologic conditions. Cosmeceutical preparations from herbal origin are most popular among consumers because these agents are mostly nontoxic and possess strong antioxidan...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Singh RP,Agarwal R

    更新日期:2009-09-01 00:00:00

  • Psychologic consequences of facial dermatoses.

    abstract::The attractiveness of the human body has always been an important issue in the fields of sociology, psychology, and psychiatry and also in the field of dermatology. In psychodermatology, one often discovers how all these fields intermingle to produce elaborate situations and extreme human difficulties. Perfect skin is...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Orion E,Wolf R

    更新日期:2014-11-01 00:00:00

  • Role of protein in cosmetics.

    abstract::Many authors recognize the beneficial effects of using protein-rich substances in formulations of various topical applications. Proteins quickly were considered useful ingredients for creating a suitable environment for healthy skin and hair because of their ability to bind water with the horny layer of skin and its a...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Secchi G

    更新日期:2008-07-01 00:00:00

  • Ethical issues in inpatient consultative dermatology.

    abstract::Ethical issues commonly arise in inpatient dermatology consultations. We describe the case of an inpatient suffering from a severe, undiagnosable skin condition that raises key principles of medical ethics. The four principles include autonomy, nonmaleficence, beneficence, and justice. Ethical situations faced by inpa...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章


    authors: Hansra NK,Shinkai K,Fox LP

    更新日期:2012-09-01 00:00:00

  • Skin typing: Fitzpatrick grading and others.

    abstract::Skin phototyping refers to a skin classification scheme based on how the skin responds to sun exposure. The Fitzpatrick classification is the most widely accepted method of skin phototyping, based on a person's tendency to sunburn and ability to tan. Apart from estimating the initial therapeutic dose of UV light, skin...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Gupta V,Sharma VK

    更新日期:2019-01-01 00:00:00

  • Chronic immunosuppression in the mature patient.

    abstract::In the ever-aging population of the world, the field of geriatrics continues to grow in importance. As human beings age, the skin undergoes a unique array of changes that predispose it to a specific set of dermatoses, infections, and neoplasms. Some of these physiologic alterations are comparable to the changes that h...

    journal_title:Clinics in dermatology

    pub_type: 杂志文章,评审


    authors: Sergeyenko AM,Rosenfeld DJ,Tsoukas MM

    更新日期:2018-01-01 00:00:00

  • Mal de Meleda: A great imitator.

    abstract::Mal de Meleda is an hereditary palmoplantar keratoderma named for the Mljet Island in Croatia. The lives of those affected by this disease represent a complex situation that encompasses members of a vulnerable group. They require enlightenment and should be approached with awareness, taking into account their overall ...

    journal_title:Clinics in dermatology

    pub_type: 历史文章,杂志文章,评审


    authors: Bakija-Konsuo A,Zitinski M,Fatovic-Ferencic S

    更新日期:2019-01-01 00:00:00