Abstract：
:The attractiveness of the human body has always been an important issue in the fields of sociology, psychology, and psychiatry and also in the field of dermatology. In psychodermatology, one often discovers how all these fields intermingle to produce elaborate situations and extreme human difficulties. Perfect skin is widely adored in literature, poetry, and biblical texts, as well as in advertisements, movies, and television. Because in most societies the face is the body part that is visible, imperfections of the skin are also visible; therefore, its flawed appearance bears the potential to become a source of misery to some.
journal_name
Clin Dermatoljournal_title
Clinics in dermatologyauthors
Orion E,Wolf Rdoi
10.1016/j.clindermatol.2014.02.016subject
Has Abstractpub_date
2014-11-01 00:00:00pages
767-71issue
6eissn
0738-081Xissn
1879-1131pii
S0738-081X(14)00050-9journal_volume
32pub_type
杂志文章,评审abstract：:Mucocutaneous diseases and conditions, including aging, are known to be the result of multiple pathophysiologic anomalies induced by various environmental insults. Creating therapeutic products for these multifactorial diseases and conditions is challenging. Although safety testing is not required for cosmetics and co...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2018.03.003
更新日期：2018-01-01 00:00:00
abstract：:While autoimmunity as cause of disease is well-established, other categories of immune-mediated diseases that are not produced by targeting of self-antigens by antibodies is in the process of being described. These so-called autoinflammatory diseases arise when an inappropriate activation of antigen-independent mechan...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2014.02.004
更新日期：2014-07-01 00:00:00
abstract：:Pyoderma gangrenosum (PG) is a rare, inflammatory, noninfective, nonneoplastic skin disorder, which is often associated with systemic diseases. These include inflammatory bowel disease, rheumatoid arthritis, paraproteinaemia, or hematologic malignancy, which can be found in up to 50% of patients with some variants of ...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2005.01.014
更新日期：2005-11-01 00:00:00
abstract：:There is a high demand for facial aesthetic enhancement, and the periorbital region is one of the first areas to show signs of aging. Many nonsurgical therapies exist to tackle these problems. These therapies are becoming more efficacious while reducing postprocedural recovery time. The goal is to restore the natural ...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2014.10.012
更新日期：2015-03-01 00:00:00
abstract：:Major gaps still exist in the knowledge about leprosy, particularly with regard to how it spreads. Leprosy epidemiology remains complicated due to the specific characteristics of Mycobacterium leprae. To describe epidemiologic trends for the 21st century, the first part of this paper gives an overview of the epidemiol...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/j.clindermatol.2015.11.001
更新日期：2016-01-01 00:00:00
abstract：:Many authors recognize the beneficial effects of using protein-rich substances in formulations of various topical applications. Proteins quickly were considered useful ingredients for creating a suitable environment for healthy skin and hair because of their ability to bind water with the horny layer of skin and its a...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2008.04.004
更新日期：2008-07-01 00:00:00
abstract：:Any infectious illness presenting with an eruption in a pregnant patient may be associated with an increased risk of fetal loss. The viruses that can infect the placenta during maternal infection and can be transmitted to the fetus and cause congenital disease include the rubella virus, the measles virus, the varicell...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/j.clindermatol.2019.10.020
更新日期：2020-01-01 00:00:00
abstract：:More than 127 loci are actually known to affect pigmentation in mouse when they are mutated. From embryogenesis to transfer of melanin to the keratinocytes or melanocytes survival, any defect is able to alter the pigmentation process. Many gene mutations are now described, but the function of their product protein and...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2004.09.013
更新日期：2005-01-01 00:00:00
abstract：:Facial erythema (the "red face") is a straightforward clinical finding, and it is evident even to the untrained eye; however, a red face does not represent a single cutaneous entity. It may be due to a plethora of distinct underlying conditions of varying severity, including rosacea, demodicosis, dermatomyositis, lupu...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2016.10.015
更新日期：2017-01-01 00:00:00
abstract：:Many studies have investigated cutaneous reactions to antitumor drugs and found them to be quite numerous. We describe drug eruptions that may be associated with different therapies by class: antimetabolite chemotherapeutics, genotoxic agents, spindle inhibitors, signal transduction inhibitors, and immunotherapies. Me...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2019.10.006
更新日期：2020-01-01 00:00:00
abstract：:Human papillomaviruses (HPV) are clearly responsible for the induction of genital lesions like condylomata acuminata, bowenoid papules, and flat condylomas. Moreover, the DNA of particular virus types (HPV 16 and 18) is found in a substantial number of invasively growing squamous cell carcinomas of the genital tract, ...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/0738-081x(85)90056-2
更新日期：1985-10-01 00:00:00
abstract：:The two main uses of antimicrobials in dermatologic surgery include prophylaxis for bacteremia and prevention of localized surgical skin infection (LSSI). Bacteremia can result in hematogenous surgical infections such as infective endocarditis and prosthetic joint infection. Comprehensive guidelines from the American ...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/j.clindermatol.2010.03.007
更新日期：2010-09-01 00:00:00
abstract：:There is an almost innate urge in human beings to represent reality in a visual form. From rock art in the Paleolithic to images of galaxies, the quotidian and the extraordinary have been visually represented through the ages. Medical and scientific disciplines are no exception. Accurate representation of the human bo...
journal_title：Clinics in dermatology
pub_type： 历史文章,杂志文章
doi：10.1016/j.clindermatol.2018.09.008
更新日期：2019-01-01 00:00:00
abstract：:Mal de Meleda is an hereditary palmoplantar keratoderma named for the Mljet Island in Croatia. The lives of those affected by this disease represent a complex situation that encompasses members of a vulnerable group. They require enlightenment and should be approached with awareness, taking into account their overall ...
journal_title：Clinics in dermatology
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.clindermatol.2019.01.003
更新日期：2019-01-01 00:00:00
abstract：:In recent years, a bewildering array of emerging rickettsial pathogens have been described throughout the world, including in the tropics. Here we present an updated overview of scrub typhus, murine typhus, and epidemic typhus. We also present an update on the emerging spotted fever group rickettsioses described in th...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2005.11.007
更新日期：2006-05-01 00:00:00
abstract：:Acne is the most common of skin diseases, being characterized as a chronic inflammatory disease of the pilosebaceous unit. Although acne is usually straightforward to diagnose and treat, some patients have difficult or rare forms of acne. What seems to be "nonresponding acne" in a patient may be caused by another acne...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/j.clindermatol.2016.10.005
更新日期：2017-01-01 00:00:00
abstract：:In summary, there is much overlap among the three types of localized cutaneous pemphigoid discussed. They all tend to affect the same age group, in general. They all may remain regional or be associated with a generalized eruption consistent with bullous pemphigoid. These three variants of subepidermal blistering dise...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/0738-081x(87)90048-4
更新日期：1987-01-01 00:00:00
abstract：:Since the introduction of botulinum toxin (BTX) as a therapeutic tool in the 1970s, the number of uses for this substance has increased exponentially. BTX's mechanism of action involves degrading the SNARE proteins blockading the release of acetylcholine into the neuromuscular junction. In many body systems, decrease ...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2003.12.030
更新日期：2004-01-01 00:00:00
abstract：:Formulating at acidic pH is a route to improve the chemical or biological stability and the performances of cosmeceuticals. Unfortunately, its potential is limited by the poor differentiation of available acidic agents, and by the risk of skin irritation. Recently, a perfluoropolyether phosphate was proposed to formul...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2008.04.005
更新日期：2008-07-01 00:00:00
abstract：:Evidence-based medicine is a redundant term to the extent that doctors have always claimed they practiced medicine on the basis of evidence. They have, however, disagreed about what exactly constitutes legitimate evidence and how to synthesize the totality of evidence in a way that supports clinical action. Despite cl...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/j.clindermatol.2013.06.004
更新日期：2013-11-01 00:00:00
abstract：:An important feature in the etiology of acne is the presence of pilosebaceous ductal hypercornification, which can be seen histologically as microcomedones (Fig 1) and clinically as blackheads, whiteheads, and other forms of comedones, such as macrocomedones. There is a significant correlation between the severity of ...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2004.03.011
更新日期：2004-09-01 00:00:00
abstract：:Optimal management of full-thickness wounds requires a thorough knowledge of wound-healing principles and practices. In the absence of underlying disease, almost every full-thickness wound will heal with minimal intervention; however, the process can be enhanced by judicious wound management. The first clinical decisi...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2006.10.001
更新日期：2007-01-01 00:00:00
abstract：:Heinrich Koebner (1838-1904) presented in a meeting in 1872 and reported in 1877 the emergence of psoriatic lesions following trauma to healthy skin areas of patients with psoriasis. Since then, the Koebner phenomenon has been the subject of research, as it offers a unique opportunity in the investigation of the disea...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/j.clindermatol.2013.05.012
更新日期：2013-11-01 00:00:00
abstract：:Less than 20 of the hundreds of carotenoids found in nature are found in the human body. These carotenoids are present in the body from the foods or dietary supplements that humans consume. The body does not synthesize them. Among the carotenoids present in the body, only lutein and its coexistent isomer, zeaxanthin, ...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2008.01.011
更新日期：2009-03-01 00:00:00
abstract：:Decorative tattoo is a popular practice that is generally safe when performed in the professional setting but can be associated with a variety of inflammatory, infectious, and neoplastic complications, risks that may be increased with current trends in home tattooing. Modern tattoo inks contain azo dyes and are often ...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/j.clindermatol.2015.07.003
更新日期：2016-03-01 00:00:00
abstract：:The development of immunotherapy has led to a paradigm shift in the treatment of both solid and hematologic malignancies. As immunomodulatory therapies are employed with increasing frequency, a greater number of immune-related adverse reactions are being reported, and the majority of these involve the skin. As a resul...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2020.06.011
更新日期：2020-01-01 00:00:00
abstract：:In 2002, new guidelines for interactions with the pharmaceutical industry and physicians were published as an official code of conduct. Adherence to the guidelines was voluntary, and there were no provisions for discipline to companies who did not subscribe to the code or who subscribed but did not comply. Many of the...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/j.clindermatol.2009.02.005
更新日期：2009-07-01 00:00:00
abstract：:Several antiepileptic drugs (AEDs) are approved by the US Food and Drug Administration for the treatment of bipolar disorder (valproic acid, divalproex, lamotrigine, carbamazepine) and some cutaneous neuropathic pain syndromes (carbamazepine, gabapentin, pregabalin). The AEDs may be effective in the management of (1) ...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2018.08.005
更新日期：2018-01-01 00:00:00
abstract：:With a prevalence of 2% to 3%, psoriasis is a very common chronic disease worldwide and generates therapy costs and continuing cost for health insurance and patients and their families. Cost-political changes in health care and the ever increasing health-economic demands in all areas of the health system make it neces...
journal_title：Clinics in dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.clindermatol.2007.10.024
更新日期：2008-09-01 00:00:00
abstract：:Dr. Ida Lystic completed her MD degree at the prestigious Harvey Medical School (which has since been renamed the Harvey Provider School) and her residency in internal medicine and gastroenterology fellowship at the OTHER (Owen T. Henry and Eugene Rutherford) Medical Center. She was subsequently hired as an assistant ...
journal_title：Clinics in dermatology
pub_type： 杂志文章
doi：10.1016/j.clindermatol.2017.03.002
更新日期：2017-01-01 00:00:00
