A confirmation study of Russian and Ukrainian data on effects of 2450 MHz microwave exposure on immunological processes and teratology in rats.

Abstract:

:In a series of Russian and Ukrainian papers published from 1974-1986, it was reported that 30-day whole-body exposures to continuous-wave (CW) radiofrequency (RF) radiation at 2375 MHz and 5 W/m(2) disrupted the antigenic structure of rat brain tissue. The authors suggested that this action caused an autoimmune response in exposed animals. Moreover, these studies reported that blood serum from exposed rats injected into intact nonexposed female rats on the 10th day of pregnancy led to increased postimplantation embryo mortality and decreased fetus size and body weight. Because the results of these studies served in part as the basis for setting exposure limits in the former USSR, it was deemed necessary to perform confirmation studies, using modern dosimetric and biological methods. In our study, a new system was constructed to expose free-moving rats under far-field conditions. Whole-body and brain-averaged specific absorption rates (SARs) were calculated. All results, using ELISA and classic teratology end points, were negative in our laboratory. On the basis of this investigation, we conclude that, under these exposure conditions (2450 MHz, CW, 7 h/day, 30 days, 0.16 W/kg whole-body SAR), RF-radiation exposure had no influence on several immune and degenerative parameters or on prenatal development.

journal_name

Radiat Res

journal_title

Radiation research

authors

de Gannes FP,Taxile M,Duleu S,Hurtier A,Haro E,Geffard M,Ruffié G,Billaudel B,Lévêque P,Dufour P,Lagroye I,Veyret B

doi

10.1667/RR1541.1

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

617-24

issue

5

eissn

0033-7587

issn

1938-5404

journal_volume

172

pub_type

杂志文章
  • The micronucleus assay of lymphocytes is a useful predictive assay of the radiosensitivity of normal tissue: a study of three inbred strains of mice.

    abstract::Radiation sensitivity was measured by the micronucleus assay in T lymphocytes of the spleen and in fibroblasts derived from three inbred strains of mice, BALB/c, A/J and C3H/He. A linear correlation between the surviving fraction and the micronucleus frequency was obtained. There were clear differences in the radiosen...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Kinashi Y,Ono K,Abe M

    更新日期:1997-10-01 00:00:00

  • Total Body Irradiation in the "Hematopoietic" Dose Range Induces Substantial Intestinal Injury in Non-Human Primates.

    abstract::The non-human primate has been a useful model for studies of human acute radiation syndrome (ARS). However, to date structural changes in various parts of the intestine after total body irradiation (TBI) have not been systematically studied in this model. Here we report on our current study of TBI-induced intestinal s...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/RR14191.1

    authors: Wang J,Shao L,Hendrickson HP,Liu L,Chang J,Luo Y,Seng J,Pouliot M,Authier S,Zhou D,Allaben W,Hauer-Jensen M

    更新日期:2015-11-01 00:00:00

  • Cancer mortality following radium treatment for uterine bleeding.

    abstract::Cancer mortality in relation to radiation dose was evaluated among 4153 women treated with intrauterine radium (226Ra) capsules for benign gynecologic bleeding disorders between 1925 and 1965. Average follow up was 26.5 years (maximum = 59.9 years). Overall, 2763 deaths were observed versus 2687 expected based on U.S....

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Inskip PD,Monson RR,Wagoner JK,Stovall M,Davis FG,Kleinerman RA,Boice JD Jr

    更新日期:1990-09-01 00:00:00

  • Exposure of Daudi cells to low-frequency magnetic fields does not elevate MYC steady-state mRNA levels.

    abstract::The effect of extremely low-frequency electromagnetic field (ELF EMF) exposures to human health has been widely debated. Epidemiological studies have found a possible correlation between increased cancer incidence and environmental ELF EMF exposures. Results from in vitro studies performed to examine the possible unde...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/0033-7587(2000)153[0663:eodctl]2.0.co;2

    authors: Morehouse CA,Owen RD

    更新日期:2000-05-01 00:00:00

  • Modulation of intercellular communication during radiation and chemical carcinogenesis.

    abstract::Carcinogenesis is a multistep process, involving the irreversible conversion of a stem cell to a terminal-differentiation-resistant cell ("initiation"), followed by the clonal expansion of this cell ("promotion") and by the acquisition of other genetic alterations leading to malignancy ("progression"). The initiation ...

    journal_title:Radiation research

    pub_type: 杂志文章,评审

    doi:

    authors: Trosko JE,Chang CC,Madhukar BV

    更新日期:1990-09-01 00:00:00

  • Human glioblastoma U87MG cells transduced with a dominant negative p53 (TP53) adenovirus construct undergo radiation-induced mitotic catastrophe.

    abstract::Human gliomas are among the most aggressive tumors, and they respond poorly to treatment. The efficacy of surgical, radiation and chemotherapy treatment of these tumors is limited by the development of resistance. Interventions aimed at altering the response of these tumors to radiation or chemotherapy treatments are ...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/0033-7587(2007)168[183:HGUCTW]2.0.CO;2

    authors: Ianzini F,Domann FE,Kosmacek EA,Phillips SL,Mackey MA

    更新日期:2007-08-01 00:00:00

  • Biological effects of radiofrequency fields: does modulation matter?

    abstract::This commentary considers modulation as a factor of potential biological importance in assessment of risk of radiofrequency (RF) energy emitted by communications systems and other technologies. Modulation introduces a spread of frequencies into a carrier waveform, but in nearly all cases this spread is small compared ...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/rr3191

    authors: Foster KR,Repacholi MH

    更新日期:2004-08-01 00:00:00

  • The role of thiols in cellular response to radiation and drugs.

    abstract::Cellular nonprotein thiols (NPSH) consist of glutathione (GSH) and other low molecular weight species such as cysteine, cysteamine, and coenzyme A. GSH is usually less than the total cellular NPSH, and with thiol reactive agents, such as diethyl maleate (DEM), its rate of depletion is in part dependent upon the cellul...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Biaglow JE,Varnes ME,Clark EP,Epp ER

    更新日期:1983-09-01 00:00:00

  • Identification of radiation-induced expression changes in nonimmortalized human T cells.

    abstract::In the event of a radiation accident or attack, it will be imperative to quickly assess the amount of radiation exposure to accurately triage victims for appropriate care. RNA-based radiation dosimetry assays offer the potential to rapidly screen thousands of individuals in an efficient and cost-effective manner. Howe...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/rr1977.1

    authors: Pogosova-Agadjanyan EL,Fan W,Georges GE,Schwartz JL,Kepler CM,Lee H,Suchanek AL,Cronk MR,Brumbaugh A,Engel JH,Yukawa M,Zhao LP,Heimfeld S,Stirewalt DL

    更新日期:2011-02-01 00:00:00

  • CBLB613: a TLR 2/6 agonist, natural lipopeptide of Mycoplasma arginini , as a novel radiation countermeasure.

    abstract::To date, there are no safe and effective drugs available for protection against ionizing radiation damage. Therefore, a great need exists to identify and develop non-toxic agents that will be useful as radioprotectors or postirradiation therapies under a variety of operational scenarios. We have developed a new pharma...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/rr2657.1

    authors: Singh VK,Ducey EJ,Fatanmi OO,Singh PK,Brown DS,Purmal A,Shakhova VV,Gudkov AV,Feinstein E,Shakhov A

    更新日期:2012-05-01 00:00:00

  • Wavelength dependence of inactivation and membrane damage to Saccharomyces cerevisiae cells by monochromatic synchrotron vacuum-uv radiation (145-190 nm).

    abstract::Using an electron storage ring as a source of radiation, the wavelength dependence of inactivation and membrane damage in yeast cells (Saccharomyces cerevisiae) was investigated in the range from 145 to 254 nm, with special reference to the effects of vacuum-uv radiation. The cells were irradiated on a Millipore filte...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Ito T,Ito A,Hieda K,Kobayashi K

    更新日期:1983-12-01 00:00:00

  • The in vitro and in vivo antitumor effects of pepleomycin alone or in combination with radiation.

    abstract::Pepleomycin is a derivative of bleomycin, which is less toxic to the host but possesses greater antitumor activity. Experiments are described here in which Chinese hamster V-79 cells in culture and a murine squamous cell carcinoma in vivo have been used to obtain survival curves for pepleomycin alone or in combination...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Sakamoto K,Komatsu K,Matsumoto Y

    更新日期:1985-05-01 00:00:00

  • Effect of gavaged chemical form of 241Am on its retention in mice.

    abstract::The retention of 241Am in mice 48 h after administration by gavage is reported here. The 241Am was given to mice in the form of either 241Am nitrate or 241Am citrate. The 241Am was also injected into rats in the same form. The homogenized livers of those rats were subsequently administered by gavage to another group o...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Hisamatsu S,Takizawa Y

    更新日期:1987-08-01 00:00:00

  • Analysis of boron distribution in vivo for boron neutron capture therapy using two different boron compounds by secondary ion mass spectrometry.

    abstract::The efficiency of boron neutron capture therapy (BNCT) for malignant gliomas depends on the selective and absolute accumulation of (10)B atoms in tumor tissues. Only two boron compounds, BPA and BSH, currently can be used clinically. However, the detailed distributions of these compounds have not been determined. Here...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/RR0501.1

    authors: Yokoyama K,Miyatake S,Kajimoto Y,Kawabata S,Doi A,Yoshida T,Okabe M,Kirihata M,Ono K,Kuroiwa T

    更新日期:2007-01-01 00:00:00

  • MRI Study on the Changes of Bone Marrow Microvascular Permeability and Fat Content after Total-Body X-Ray Irradiation.

    abstract::In this study, we investigated microvascular perfusion status, changes to fat content and fatty acid composition in the bone marrow of rat femurs after total-body irradiation by quantitative permeability parameters of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and ex vivo high-resolution magic angl...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/RR14865.1

    authors: Wang K,Zha Y,Lei H,Xu X

    更新日期:2018-02-01 00:00:00

  • Effects of reoxygenation on repair of potentially lethal radiation damage in cultured MG-63 osteosarcoma cells.

    abstract::The effects of reoxygenation on repair of potentially lethal radiation damage were investigated using MG-63 human osteosarcoma cells in vitro. When exponentially growing MG-63 cells were cultured under hypoxic conditions for 24 h, cells stopped growing and remained at a low density. The hypoxic cells were then reoxyge...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Iizuka M,Ando K,Aruga T,Furusawa Y,Itsukaichi H,Fukutsu K,Nagasawa H,Moriya H

    更新日期:1997-02-01 00:00:00

  • Suramin sensitizing cells to ionizing radiation by inactivating DNA-dependent protein kinase.

    abstract::Here we report that suramin sensitizes LM217, MDA-MB-468, T98G and A431 cells to ionizing radiation. Suramin sensitized cells to X radiation in a dose-dependent fashion, and longer exposure to suramin before X irradiation resulted in more efficient sensitization. The dose-modifying factors calculated from the survival...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/rr3217

    authors: Hosoi Y,Matsumoto Y,Enomoto A,Morita A,Green J,Nakagawa K,Naruse K,Suzuki N

    更新日期:2004-09-01 00:00:00

  • A comparison of the natural survival of beagle dogs injected intravenously with low levels of 239Pu, 226Ra, 228Ra, 228Th, or 90Sr.

    abstract::The natural survival, relative to properly chosen controls, of 26 beagle dogs injected once intravenously with an average of 0.58 +/- 0.04 kBq 239Pu/kg, 23 dogs injected with 2.31 +/- 0.43 kBq 226Ra/kg, 13 dogs injected with 1.84 +/- 0.26 kBq 228Ra/kg, 12 dogs injected with 0.56 +/- 0.030 kBq 228Th/kg, and 12 dogs inj...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Bruenger FW,Miller SC,Lloyd RD

    更新日期:1991-06-01 00:00:00

  • Hiroshima-like neutrons from A-bomb replica: physical basis for their use in biological experiments.

    abstract::The lineal energy distribution and several other dosimetric parameters were measured for the neutrons emitted from a replica of the Hiroshima bomb to determine their usefulness in biological experiments designed to estimate the effectiveness of actual Hiroshima neutrons. The "Little-Boy" replica (LBR) was constructed ...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Straume T,McDonald JC,Pederson RA,Brenner DJ,Dobson RL

    更新日期:1991-11-01 00:00:00

  • Prevention and treatment of the gastric symptoms of radiation sickness.

    abstract::Currently available treatments for radiation-induced nausea and vomiting either are ineffective or reduce performance. The new antiemetic and gastrokinetic agent zacopride was tested in rhesus monkeys to assess its behavioral toxicity and its ability to inhibit radiation-induced emesis. Zacopride (intragastric, 0.3 mg...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Dubois A,Fiala N,Boward CA,Bogo V

    更新日期:1988-09-01 00:00:00

  • Radiation abolishes inducer binding to lactose repressor.

    abstract::The lactose operon functions under the control of the repressor-operator system. Binding of the repressor to the operator prevents the expression of the structural genes. This interaction can be destroyed by the binding of an inducer to the repressor. If ionizing radiations damage the partners, a dramatic dysfunction ...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/rr3336

    authors: Gillard N,Spotheim-Maurizot M,Charlier M

    更新日期:2005-04-01 00:00:00

  • Evidence of the formation of different hydroperoxides in irradiated gamma-linolenate solutions: effect of micelle formation.

    abstract::Peroxidation of unconjugated polyunsaturated fatty acids such as linolenic acid proceeds through a free radical chain mechanism and is accompanied by the formation of conjugated dienes such as hydroperoxides. In an investigation of radiation-induced oxidation of aqueous linolenate, we have measured two indexes of pero...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/0033-7587(2000)153[0201:eotfod]2.0.co;2

    authors: Hindo J,Hauville C,Rémita S,Thérond P,Couturier M,Jore D,Gardès-Albert M

    更新日期:2000-02-01 00:00:00

  • 50 Years of the Radiological Research Accelerator Facility (RARAF).

    abstract::The Radiological Research Accelerator Facility (RARAF) is in its 50th year of operation. It was commissioned on April 1, 1967 as a collaboration between the Radiological Research Laboratory (RRL) of Columbia University, and members of the Medical Research Center of Brookhaven National Laboratory (BNL). It was initiall...

    journal_title:Radiation research

    pub_type: 历史文章,杂志文章

    doi:10.1667/RR002CC.1

    authors: Marino SA

    更新日期:2017-04-01 00:00:00

  • Extremely low-frequency electromagnetic fields do not affect DNA damage and gene expression profiles of yeast and human lymphocytes.

    abstract::We studied the effects of extremely low-frequency (50 Hz) electromagnetic fields (EMFs) on peripheral human blood lymphocytes and DBY747 Saccharomyces cerevisiae. Graded exposure to 50 Hz magnetic flux density was obtained with a Helmholtz coil system set at 1, 10 or 100 microT for 18 h. The effects of EMFs on DNA dam...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/rr3426.1

    authors: Luceri C,De Filippo C,Giovannelli L,Blangiardo M,Cavalieri D,Aglietti F,Pampaloni M,Andreuccetti D,Pieri L,Bambi F,Biggeri A,Dolara P

    更新日期:2005-09-01 00:00:00

  • Environmental effects on primary radical formation in guanine: solid-state ESR and ENDOR of guanine hydrobromide monohydrate.

    abstract::Single crystals of guanine hydrobromide monohydrate, in which the guanine base is protonated at N7, were X-irradiated at 8 and 65 K. Using K-band ESR, ENDOR, and field-swept-ENDOR (FSE) techniques, the crystals were studied between 8 K and room temperature. There was evidence for five different radicals, RI-RV, immedi...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Hole EO,Sagstuen E,Nelson WH,Close DM

    更新日期:1991-02-01 00:00:00

  • Oncogenic transformation of C3H 10T1/2 cells by acute and protracted exposures to monoenergetic neutrons.

    abstract::An in vitro assay was used to assess cell killing and induction of neoplastic transformation in C3H 10T1/2 cells exposed to X rays and a range of monoenergetic neutrons administered at various dose rates. Curves for cell survival and induction of neoplastic transformation showed nonlinearity for cells exposed to acute...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Miller RC,Hall EJ

    更新日期:1991-10-01 00:00:00

  • Effects of extracellular and intracellular pH on repair of potentially lethal damage, chromosome aberrations and DNA double-strand breaks in irradiated plateau-phase A549 cells.

    abstract::Plateau-phase A549 cells exhibit a high capacity for repair of potentially lethal radiation damage (PLD). Previously it was found that PLD repair could be partially inhibited by increasing the extracellular pH (pHe) of the spent medium from its normal value of 6.7-6.8 to 7.6 during postirradiation holding. The present...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Jayanth VR,Bayne MT,Varnes ME

    更新日期:1994-08-01 00:00:00

  • Recovery from effects of heat on DNA synthesis in Chinese hamster ovary cells.

    abstract::The hyperthermic inhibition of cellular DNA synthesis, i.e., reduction in replicon initiation and delay in DNA chain elongation, was previously postulated to be involved in the induction of chromosomal aberrations believed to be largely responsible for killing S-phase cells. Utilizing asynchronous Chinese hamster ovar...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:

    authors: Wong RS,Thompson LL,Dewey WC

    更新日期:1988-04-01 00:00:00

  • Fruit Flies Provide New Insights in Low-Radiation Background Biology at the INFN Underground Gran Sasso National Laboratory (LNGS).

    abstract::Deep underground laboratories (DULs) were originally created to host particle, astroparticle or nuclear physics experiments requiring a low-background environment with vastly reduced levels of cosmic-ray particle interference. More recently, the range of science projects requiring an underground experiment site has gr...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/RR15083.1

    authors: Morciano P,Cipressa F,Porrazzo A,Esposito G,Tabocchini MA,Cenci G

    更新日期:2018-09-01 00:00:00

  • Accumulation of DNA damage and cell death after fractionated irradiation.

    abstract::The purpose of this work was to determine how fractionated radiation used in the treatment of tumors affects the ability of cancer as well as normal cells to repair induced DNA double-strand breaks (DSBs) and how cells that have lost this ability die. Lymphocytic leukemia cells (MOLT4) were used as an experimental mod...

    journal_title:Radiation research

    pub_type: 杂志文章

    doi:10.1667/RR2478.1

    authors: Rezáčová M,Rudolfová G,Tichý A,Bačíková A,Mutná D,Havelek R,Vávrová J,Odrážka K,Lukášová E,Kozubek S

    更新日期:2011-06-01 00:00:00