Initial liver involvement in acute GVHD is predictive for nonrelapse mortality.

abstract：BACKGROUND:Many models of transplant tolerance have been found to depend on the induction of regulatory T cells (Tregs). Innate immune signals are known to suppress Tregs thereby augmenting immunity by abrogating Treg function. Such signals may also provide a barrier to transplantation tolerance mediated by Tregs. A nu...

journal_title：Transplantation

authors： Sonawane SB,Kim JI,Lee MK,Lee SH,Duff PE,Moore DJ,Lian MM,Deng S,Choi Y,Yeh H,Caton AJ,Markmann JF

更新日期：2009-11-27 00:00:00

abstract：:Uncontrolled donation after circulatory death (uDCD) refers to donation from persons who die following an unexpected and unsuccessfully resuscitated cardiac arrest. Despite the large potential for uDCD, programs of this kind only exist in a reduced number of countries with a limited activity. Barriers to uDCD are of a...

journal_title：Transplantation

authors： Coll E,Miñambres E,Sánchez-Fructuoso A,Fondevila C,Campo-Cañaveral de la Cruz JL,Domínguez-Gil B

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Posttransplant anemia and its association with transplant outcomes have not been properly studied. METHODS:We examined 530 renal allograft recipients transplanted at our center and followed up for 31.0±14.1 months. Hemoglobin (Hb), serum bicarbonate, and creatinine; use of erythropoiesis-stimulating agent...

journal_title：Transplantation

authors： Jones H,Talwar M,Nogueira JM,Ugarte R,Cangro C,Rasheed H,Klassen DK,Weir MR,Haririan A

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:Given growth in kidney transplant waitlists and discard rates, donor kidney acceptance is an important problem. We used network analysis to examine whether organ procurement organization (OPO) network centrality affects discard and outcomes. METHODS:We identified 106,160 deceased donor kidneys recovered for...

journal_title：Transplantation

authors： Butala NM,King MD,Reitsma W,Formica RN,Abt PL,Reese PP,Parikh CR

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The authors have investigated the effectiveness of virus detection from bronchoalveolar lavage (BAL) samples for the identification of symptomatic cytomegalovirus (CMV) infection in lung transplant recipients. METHODS:Thus, 275 BAL samples taken from 105 lung transplant recipients during follow-up were anal...

journal_title：Transplantation

authors： Zedtwitz-Liebenstein K,Jaksch P,Bauer C,Popow T,Klepetko W,Hofmann H,Puchhammer-Stöckl E

更新日期：2004-06-27 00:00:00

abstract：BACKGROUND:The long-term outcome of lung transplantation is impeded by the development of obliterative bronchiolitis (OB). We sought to investigate the relationship between the apoptosis of tracheal epithelial cells and bone marrow-derived myofibroblasts in the process of OB. METHODS:The mouse orthotopic tracheal tran...

journal_title：Transplantation

authors： Wang C,Xia T,Jiang K,Qiao X,Zhang X,Li J,Wang J,Nie J

更新日期：2016-09-01 00:00:00

abstract：:Donor graft major histocompatibility complex class I antigens are targets for both allogeneic and xenogeneic rejection. Mice homozygous for beta 2-microglobulin gene disruption express reduced amounts of surface MHC class I antigens. Liver cells from such mutant mice were transplanted into isogeneic, allogeneic, and x...

journal_title：Transplantation

authors： Li X,Faustman D

更新日期：1993-04-01 00:00:00

abstract：:The pig has been considered unsuitable for experimental pancreatic transplantation. In order to develop a model for segmental transplantation, the vascular anatomy was studied in 41 pigs. No variation in venous drainage of the pancrease was found. In contrast, 3 variations of arterial supply were noted. In 29 of the p...

journal_title：Transplantation

authors： Shokouh-Amiri MH,Rahimi-Saber S,Andersen HO

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Thromboembolism has been reported as a frequent complication after cardiac transplantation. Many risk factors for thrombosis may explain this, such as metabolic alterations and the use of cyclosporine. In the general population, two single nucleotide polymorphisms (SNPs), factor V Leiden and prothrombin G202...

journal_title：Transplantation

authors： Miriuka SG,Langman LJ,Evrovski J,Miner SE,Kozuszko S,D'Mello N,Delgado DH,Wong BY,Ross HJ,Cole DE

更新日期：2005-09-15 00:00:00

abstract：BACKGROUND:Elastase released from activated neutrophils is an important mediator of inflammatory tissue damage. We investigated the effect of human neutrophil elastase (NE) inhibitor (ONO-5046) on reperfusion injury after pancreaticoduodenal transplantation in rats by measuring the expression of intercellular adhesion ...

journal_title：Transplantation

authors： Yamaguchi Y,Matsumura F,Wang FS,Akizuki E,Liang J,Matsuda T,Okabe K,Ohshiro H,Horiuchi T,Yamada S,Mori K,Ogawa M

更新日期：1998-06-27 00:00:00

abstract：:CD2 is a 50-kDa transmembrane glycoprotein that plays an important role in T and natural killer (NT) lymphocyte functions. CD2 serves as both an adhesion molecule and as a costimulatory molecule through interactions with its ligand, CD58, on antigen presenting or target cells. Consistent with earlier studies using a r...

journal_title：Transplantation

authors： Branco L,Barren P,Mao SY,Pfarr D,Kaplan R,Postema C,Langermann S,Koenig S,Johnson S

更新日期：1999-11-27 00:00:00

abstract：:A total of 151 potential recipients of kidney grafts from one-HLA-haplotype-mismatched MLC-positive (RR greater than 20%) donors treated during 1980-1984 was investigated. The recipients were divided retrospectively into four groups: (A) 42 patients who received pretransplant donor-specific transfusions (DST) and post...

journal_title：Transplantation

authors： Leivestad T,Albrechtsen D,Flatmark A,Thorsby E

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:A regimen consisting of antilymphocyte serum (ALS), sirolimus, and donor bone-marrow-cell (BMC) infusion induces indefinite skin allograft survival across fully mismatched mouse strain combinations. We investigated the role of chimerism in this transplantation tolerance model. MATERIALS:B10.A (H-2a) mice we...

journal_title：Transplantation

authors： Kanamoto A,Monaco AP,Maki T

更新日期：2004-09-27 00:00:00

abstract：:A retrospective study of the 99 surviving heart and lung transplant (HLT) recipients at one center showed that 31% had significant anemia (hemoglobin less than 100g/L) six months after transplantation. Chronic anemia persisted in 18% of HLT recipients two years posttransplantation. A similar study of 100 heart transpl...

journal_title：Transplantation

authors： Hunt BJ,Amin S,Halil O,Yacoub M

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:This study evaluated zoom endoscopic findings according to four components in comparison with the histologic findings of acute cellular rejection (ACR) in a living-related small bowel transplantation (SBTx) patient. METHODS:A 16-year-old boy with microvillus inclusion disease underwent SBTx with a 150-cm-lo...

journal_title：Transplantation

authors： Sasaki T,Hasegawa T,Nakai H,Kimura T,Okada A,Musiake S,Doi R

更新日期：2002-02-27 00:00:00

abstract：BACKGROUND:The hepatic arteries (HAs) in a hepatic graft are usually reconstructed using the recipient's left or right HAs in living donor liver transplantation (LDLT). There have been no apparent selection criteria concerning which of the recipient's HAs should be used. This study retrospectively investigated whether ...

journal_title：Transplantation

authors： Uchiyama H,Ikegami T,Soejima Y,Ninomiya M,Kayashima H,Taketomi A,Shirabe K,Maehara Y

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:While previous surveys have demonstrated the psychological impact on living-related liver transplantation (LRLT) donors, such as anxiety, depression, ambivalence and anger, the details regarding the relevant factors that affect donors' psychological status have not been well described. METHODS:To evaluate e...

journal_title：Transplantation

authors： Hayashi A,Noma S,Uehara M,Kuwabara H,Tanaka S,Furuno Y,Hayashi T

更新日期：2007-11-27 00:00:00

abstract：BACKGROUND:This study aims to verify the condition of recipients of solid organs from donors with central nervous system (CNS) tumors and determine the risk of disease transmission due to transplantation. METHODS:Twenty-eight brain-dead organ donors with CNS tumors and 91 recipients who received solid organs from Janu...

journal_title：Transplantation

authors： Lee MS,Cho WH,Ha J,Yu ES,Jeong YS,Oh JS,Lee JR,Lee JM

更新日期：2020-03-01 00:00:00

abstract：:The new class of immunosuppressants--inhibitors of the mammalian target of rapamycin--has no nephrotoxicity and the capacity to inhibit vascular smooth cell proliferation. These characteristics may afford considerable clinical advantages in the transplantation of kidneys from expanded criteria donors (ECD). Six clinic...

journal_title：Transplantation

authors： Rigotti P,Kahan BD

更新日期：2009-04-27 00:00:00

abstract：:A major impediment to the wider application of clinical liver transplantation is the paucity of acceptable organs. Most centers refuse organs that come from donors who are hepatitis B core antibody positive because of a fear of transmission of hepatitis B virus (HBV) infection to the recipient. The risk related to the...

journal_title：Transplantation

authors： Van Thiel DH,De Maria N,Colantoni A,Friedlander L

更新日期：1999-08-27 00:00:00

abstract：BACKGROUND:Umbilical cord blood transplantation (UCBT) is increasingly used and produces similar results to matched unrelated donor transplantation. METHODS:We performed a retrospective single-center analysis of 50 umbilical cord blood transplantations UCBTs performed from 2001 to 2010, including 37 single and 13 doub...

journal_title：Transplantation

authors： Berglund S,Le Blanc K,Remberger M,Gertow J,Uzunel M,Svenberg P,Winiarski J,Ljungman P,Ringdén O,Uhlin M,Mattsson J

更新日期：2012-11-27 00:00:00

abstract：:Graft-versus-host disease (GVHD)* is a frequent complication of allogeneic bone marrow transplantation. The potentially beneficial effect of phototherapy for treatment of cutaneous manifestations of GVHD led us to investigate retrospectively the effect of this therapy in a larger series of patients. Eleven patients wi...

journal_title：Transplantation

authors： Aubin F,Brion A,Deconinck E,Plouvier E,Hervé P,Humbert P,Cahn JY

更新日期：1995-01-15 00:00:00

abstract：:A technique of orthotopic renal transplantation in rabbits is described. The technique has been evolved in an experience of over 400 grafts, and difficulties encountered in producing satisfactory anaesthesia and techniques of anastomosis and in obtaining reliable graft function postoperatively have been defined and ov...

journal_title：Transplantation

authors： Dunn DC

更新日期：1976-11-01 00:00:00

abstract：:Since 1981, when the liver transplantation program was initiated at the University of Pittsburgh, we have been impressed with the prevalence of pancreatitis occurring following liver transplantation in patients transplanted for hepatitis B-related liver disease. To either confirm this clinical impression or refute it,...

journal_title：Transplantation

authors： Alexander JA,Demetrius AJ,Gavaler JS,Makowka L,Starzl TE,Van Thiel DH

更新日期：1988-06-01 00:00:00

abstract：:Pulmonary endothelium is considered the compartment most susceptible to preservation damage. This investigation was designed to analyze the efficacy of an original, University of Parma low-potassium-albumin solution (SPAL UP) on cultured human pulmonary artery endothelial cells (HPAEC) and to compare its effects with ...

journal_title：Transplantation

authors： Spaggiari L,Rusca M,Carbognani P,Alfieri R,Urbani S,Cattelani L,Petronini P,Solli P,Borghetti AF,Bobbio P

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:T-cell activation through T-cell receptor engagement requires co-stimulatory molecules and also adhesion molecules such as ICAM-1. Moreover ICAM-1 mediates leukocyte invasion from the blood into tissue during inflammatory processes. In animal studies using mouse monoclonal antibodies against ICAM-1 (enlimoma...

journal_title：Transplantation

authors： Salmela K,Wramner L,Ekberg H,Hauser I,Bentdal O,Lins LE,Isoniemi H,Bäckman L,Persson N,Neumayer HH,Jørgensen PF,Spieker C,Hendry B,Nicholls A,Kirste G,Hasche G

更新日期：1999-03-15 00:00:00

abstract：:Acute rejection episodes still occur after kidney transplantation in spite of modern immunosuppressive protocols including combined tacrolimus, mycophenolate mofetil, and prednisolone. The authors present seven cases of biopsy-proven acute rejection after kidney transplantation refractory to conventional rejection the...

journal_title：Transplantation

authors： Kumlien G,Genberg H,Shanwell A,Tydén G

更新日期：2005-01-15 00:00:00

abstract：:Predictors of survival after lung transplant were analyzed in a large cohort of 990 lung transplanted patients from a single center. The overall survival was 41.6%, (41.5% in males, and 41.8% in females), the average length of the follow up was 45.84+/-51.98 months (range 0-282.47 months). Females tend to live longer ...

journal_title：Transplantation

authors： Creel M,Studer SM,Schwerha J,Harper J,Ortiz L,Ragin C,Taioli E

更新日期：2008-04-27 00:00:00

abstract：BACKGROUND:Current insulin therapies for control of glucose metabolism in patients with type I diabetes mellitus prevent major metabolic consequences of insulin deficiency, but none prevents or arrests long-term complications. In experimental models of canine diabetes, retinopathy, neuropathy, and nephropathy have been...

journal_title：Transplantation

authors： Hawthorne WJ,Wilson TG,Williamson P,Stewart GJ,Allen RD,Little JM,Deane SA,Ekberg H

更新日期：1997-10-15 00:00:00

abstract：BACKGROUND:Localization of inflammatory stimuli may direct lung allografts to different phenotypes of chronic dysfunction, such as bronchiolitis obliterans syndrome (BOS) or restrictive allograft syndrome (RAS). We hypothesized that airway stimulation with lipopolysaccharide (LPS) in rats leads to airway-centered infla...

journal_title：Transplantation

authors： Takahagi A,Sato M,Chen-Yoshikawa TF,Miyamoto E,Saito M,Gochi F,Hamaji M,Yoshizawa A,Terasaki Y,Urushiyama H,Aoyama A,Sonobe M,Date H

更新日期：2020-06-01 00:00:00