Abstract：
:Breast-conserving surgery combined with subsequent radiation therapy is a standard procedure in breast cancer treatment. The disadvantage of whole-breast beam irradiation is that it requires 20-25 treatment days, which is inconvenient for patients with limited mobility or who reside far from the treatment center. However, interstitial high-dose-rate (HDR) brachytherapy is an irradiation method requiring only 5 treatment days and that delivers a lower radiation dose to the surrounding healthy tissue. It involves delivering radiation through 192Ir seeds placed inside the catheters, which are inserted into the breast. The catheters are attached to a HDR afterloader, which controls the seed placement within the catheters and irradiation times to deliver the proper radiation dose. One disadvantage of using HDR brachytherapy is that it requires performing at least one CT scan during treatment planning. The procedure at our institution involves the use of two CT scans. Performing CT scans requires moving the patient from the brachytherapy suite with catheters inserted in their breasts. One alternative is using three-dimensional ultrasound (3DUS) to image the patient. In this study, the authors developed a 3DUS translation scanning system for use in breast brachytherapy. The new system was validated using CT, the current clinical standard, to image catheters in a breast phantom. Once the CT and 3DUS images were registered, the catheter trajectories were then compared. The results showed that the average angular separation between catheter trajectories was 2.4 degrees, the average maximum trajectory separation was 1.0 mm, and the average mean trajectory separation was found to be 0.7 mm. In this article, the authors present the 3DUS translation scanning system's capabilities as well as its potential to be used as the primary treatment planning imaging modality in breast brachytherapy.
journal_name
Med Physjournal_title
Medical physicsauthors
De Jean P,Beaulieu L,Fenster Adoi
10.1118/1.3243865subject
Has Abstractpub_date
2009-11-01 00:00:00pages
5099-106issue
11eissn
0094-2405issn
2473-4209journal_volume
36pub_type
杂志文章相关文献
MEDICAL PHYSICS文献大全abstract：:The method of magnetic resonance imaging (MRI) was an extension of nuclear magnetic resonance (NMR) spectroscopy that was enabled by computational systems capable of performing the Fast Fourier Transform. Initially, a diverse group of methods were proposed for producing images with NMR, with the multi-slice spin-warp ...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4736176
更新日期：2012-06-01 00:00:00
abstract：:The dosimetry protocols DIN 6800-2 and AAPM TG-51, both based on the absorbed dose to water concept, are compared in their theoretical background and in their application to electron dosimetry. The agreement and disagreement in correction factors and energy parameters used in both protocols will be shown and discussed...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.1414008
更新日期：2001-11-01 00:00:00
abstract：:Rotational angiography (RA) gantries are used routinely to acquire sequences of projection images of patients from which 3D renderings of vascular structures are generated using Feldkamp cone-beam reconstruction algorithms. However, these systems have limited resolution (<4 lp/mm). Micro-computed tomography (micro-CT)...
journal_title：Medical physics
pub_type： 信件
doi：10.1118/1.2989989
更新日期：2008-10-01 00:00:00
abstract：PURPOSE:Couch-mounted cone-beam computed tomography (CBCT) imaging devices with independently rotatable x-ray source and flat-panel detector arms for acquisitions of arbitrary regions of interest (ROI) have recently been introduced in image-guided radiotherapy (IGRT). This work analyzes mechanical limitations and gravi...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.12033
更新日期：2017-01-01 00:00:00
abstract：:Total scalp irradiation is a treatment technique used for a variety of superficial malignancies. Helical tomotherapy is an effective technique used for total scalp irradiation. Recent published work has shown the TomoTherapy planning system to overestimate the superficial dose. In this study, the superficial doses for...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.2996288
更新日期：2008-11-01 00:00:00
abstract：PURPOSE:Liver segmentation is an important prerequisite for the assessment of liver cancer treatment options like tumor resection, image-guided radiation therapy (IGRT), radiofrequency ablation, etc. The purpose of this work was to evaluate a new approach for liver segmentation. METHODS:A graph cuts segmentation metho...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.3682171
更新日期：2012-03-01 00:00:00
abstract：PURPOSE:Dual-energy computed tomography and dual-energy cone-beam computed tomography (DE-CBCT) are promising modalities for applications ranging from vascular to breast, renal, hepatic, and musculoskeletal imaging. Accordingly, the optimization of imaging techniques for such applications would benefit significantly fr...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4736420
更新日期：2012-08-01 00:00:00
abstract：PURPOSE:Brachytherapy with 106 Ru/106 Rh plaques offers good outcomes for small-to-medium choroidal melanomas and retinoblastomas. The dose measurement of the plaques is challenging, due to the small range of the emitted beta particles and steep dose gradients involved. The scarce publications on film dosimetry of 106 ...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.12777
更新日期：2018-04-01 00:00:00
abstract：:In intensity modulated radiation treatments (IMRT), the position of the field edges and the modulation within the beam are often achieved with a multileaf collimator (MLC). During the MLC calibration process, due to the finite accuracy of leaf position measurements, a systematic error may be introduced to leaf positio...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.2335490
更新日期：2006-09-01 00:00:00
abstract：:Interstitial brachytherapy for carcinoma of the prostate is achieved through the use of a configuration of radioactive seeds placed in a manner that delivers a customized, reasonably uniform dose to the target volume. Accurate dose delivery depends on both precise seed placement and reliable seed strength in the impla...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.598877
更新日期：2000-01-01 00:00:00
abstract：:The modulation transfer function (MTF) and the noise power spectrum (NPS) are widely recognized as the most relevant metrics of resolution and noise performance in radiographic imaging. These quantities have commonly been measured using various techniques, the specifics of which can have a bearing on the accuracy of t...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.2188816
更新日期：2006-05-01 00:00:00
abstract：:Positron emission tomography (PET) is increasingly considered as an effective imaging method to support several stages of radiation therapy. The combined usage of functional and morphological imaging in state-of-the-art PET/CT scanners is rapidly emerging to support the treatment planning process in terms of improved ...
journal_title：Medical physics
pub_type： 杂志文章,评审
doi：10.1118/1.4935869
更新日期：2015-12-01 00:00:00
abstract：PURPOSE:In prostate radiotherapy, dose distribution may be calculated on CT images, while the MRI can be used to enhance soft tissue visualization. Therefore, a registration between MR and CT images could improve the overall treatment planning process, by improving visualization with a demonstrated interobserver deline...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.12629
更新日期：2017-12-01 00:00:00
abstract：PURPOSE:Ultrasound-induced mild hyperthermia has advantages for noninvasive, localized and controlled drug delivery. In this study, a tissue-mimicking agarose-based phantom with a thermally sensitive indicator was developed for studying the spatial drug delivery profile using ultrasound-induced mild hyperthermia. METH...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4813299
更新日期：2013-08-01 00:00:00
abstract：:System modeling is used to investigate the effect of various system parameters on the image quality in CCD-based x-ray imaging systems. The systems considered consist of a typical phosphor-based scintillating screen coupled to a CCD through lens or fiberoptic taper. Two applications, chest radiography and mammography,...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.598072
更新日期：1997-02-01 00:00:00
abstract：PURPOSE:Periodic MV∕KV radiographs taken during volumetric modulated arc therapy (VMAT) for hypofractionated treatment provide guidance in intrafractional motion management. The choice of imaging frequency and timing are key components in delivering the desired dose while reducing associated overhead such as imaging do...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4742846
更新日期：2012-09-01 00:00:00
abstract：PURPOSE:The purposes of this study is to measure the low frequency drop (LFD) of the modulation transfer function (MTF), associated with the long tails of the detector point spread function (PSF) of an on-board flat panel imager and study its impact on cone-beam CT (CBCT) image quality and scatter measurement accuracy....
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4747260
更新日期：2012-09-01 00:00:00
abstract：:In computer simulations of x-ray CT systems one can either use continuous geometrical descriptions for phantoms or a voxelized representation. The voxelized approach allows arbitrary phantoms to be defined without being confined to geometrical shapes. The disadvantage of the voxelized approach is that inherent errors ...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.1461841
更新日期：2002-04-01 00:00:00
abstract：:A method is developed to smooth intensity-modulated beam delivery while considering hardware constraints. The method uses matrix algebra to model MLC leaf motion and hardware constraints such as interleaf digitization, synchronization requirements, and intersegment field abutment to deliver intensity modulated beam se...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.1521121
更新日期：2002-12-01 00:00:00
abstract：:An analytic representation proposed for the relative intensity distribution of the extra-focal source in a two-component x-ray source model serves as the basis for calculation. From this representation, a closed-form expression for head scatter factors defined on the central beam axis is derived by integrating over th...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.597494
更新日期：1995-12-01 00:00:00
abstract：PURPOSE:The extensive use of computed tomography (CT) in diagnostic procedures is accompanied by a growing need for more accurate and patient-specific dosimetry techniques. Optically stimulated luminescent dosimeters (OSLDs) offer a potential solution for patient-specific CT point-based surface dosimetry by measuring a...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4914398
更新日期：2015-04-01 00:00:00
abstract：:The fast imaging method named skipped phase encoding and edge deghosting (SPEED) has been demonstrated to reduce scan time considerably with typical magnetic resonance imaging data. In this work, SPEED is simplified with improved efficiency to accelerate the scan of sparse objects; we refer to this method as S-SPEED. ...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.2750966
更新日期：2007-08-01 00:00:00
abstract：:The effects of small cavities on dose in water and the dose in a homogeneous nonunit density medium illustrate that inhomogeneities do not act independently in photon dose perturbation, and serve as two constraints which should be satisfied by approximate methods of computed tomography (CT) pixel-based dose calculatio...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.595294
更新日期：1983-03-01 00:00:00
abstract：PURPOSE:The measurement of malignant pleural mesothelioma is critical to the assessment of tumor response to therapy. Current response assessment standards utilize summed linear measurements acquired on three computed tomography (CT) sections. The purpose of this study was to evaluate manual area measurements as an alt...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4810940
更新日期：2013-08-01 00:00:00
abstract：PURPOSE:The thermoluminescence dosimeter (TLD) has desirable features including low cost, reusability, small size, and relatively low energy dependence. However, the commonly available poly-crystal TLDs (e.g., TLD-100) exhibit high interdetector variability that requires individual calibration for high detection accura...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.13895
更新日期：2020-01-01 00:00:00
abstract：:Nuclear magnetic resonance (NMR) imaging of perfluorocarbon (PFC) emulsions and neat liquids has shown potential for in vivo oxygen imaging in blood and organ tissue. PFC compounds exhibit complicated NMR spectra caused by chemical shifts and spin-spin couplings which can lead to artifacts and degraded spatial resolut...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.595960
更新日期：1986-07-01 00:00:00
abstract：:Inherent in the line-spread function approach in modulation transfer function (MTF) determinations is the use of a microdensitometer to scan the density pattern resulting from the line exposure. In such a procedure, loss of fidelity in the distribution being scanned is expected. This loss is due in part to the use of ...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.594187
更新日期：1975-09-01 00:00:00
abstract：:In a recent paper of Miller et al. (Med. Phys. 43(5), 2141-2152 (2016), the voltage dependence polarity effect of microionization chambers was studied. It was identified that polarity effect arises from the difference in electric potential between the collecting electrode and the guard electrode, which in turn deforms...
journal_title：Medical physics
pub_type： 信件
doi：10.1002/mp.12019
更新日期：2017-03-01 00:00:00
abstract：:Over the past decade, computed tomography (CT) theory, techniques and applications have undergone a rapid development. Since CT is so practical and useful, undoubtedly CT technology will continue advancing biomedical and non-biomedical applications. In this outlook article, we share our opinions on the research and de...
journal_title：Medical physics
pub_type： 杂志文章,评审
doi：10.1118/1.2836950
更新日期：2008-03-01 00:00:00
abstract：:In this work, we present a calcification-detection scheme that automatically localizes calcifications in a previously detected cluster in order to generate the input for a cluster-classification scheme developed in the past. The calcification-detection scheme makes use of three pieces of a priori information: the loca...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.1559884
更新日期：2003-05-01 00:00:00
