Abstract:
BACKGROUND:Preoperative prognostic information to select a treatment strategy is important especially in patients who need highly aggressive surgery, such as those with biliary cancer. We evaluated various prognostic factors and non-curative surgical factors using multidetector computed tomography (MDCT). METHODS:We retrospectively analyzed 71 patients who underwent MDCT preoperatively and were scheduled for surgical resection of biliary cancer. For MDCT diagnosis, we used MDCT-based classification equivalent to the surgical and pathological classification of the Japanese Society of Biliary Surgery. We evaluated MDCT-related prognostic factors and non-curative surgical factors and compared these factors with pathological results. RESULTS:MDCT-diagnosed category T (primary tumor invasion) included both prognostic factors and non-curative surgical factors but not category N (lymph node metastasis). Multivariate analysis identified MDCT-based suspected arterial invasion as an independent prognostic factor. In patients suspected of arterial invasion by MDCT, the 3-year overall survival rate was only 39% and the curative resection ratio was only 33%, because of the high positive surgical dissected margin. CONCLUSION:MDCT-based suspected arterial invasion is a predictor of poor prognosis after surgery for biliary cancer and represents a non-curative surgical factor associated with positive dissected margin.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Kobayashi S,Nagano H,Marubashi S,Wada H,Eguchi H,Takeda Y,Tanemura M,Kim T,Doki Y,Mori Mdoi
10.1002/jso.21501subject
Has Abstractpub_date
2010-04-01 00:00:00pages
376-83issue
5eissn
0022-4790issn
1096-9098journal_volume
101pub_type
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