Abstract:
:Local recurrence rates after either low anterior resection or abdominoperineal resection were compared in 109 patients undergoing curative surgery for adenocarcinoma of the rectum between 1979 and 1984. Follow-up information was available for 99 patients (91%). The overall recurrence rate was 19%; ten recurrences (26.3%) for low anterior resections and nine (14.7%) for abdominoperineal resections. (P less than .08). Recurrences were confirmed by biopsy or at reoperation. No significant difference in size of the lesion was evident at initial resection (average largest dimension 4.8 cm for low anterior and 5.5 cm for abdominoperineal resection). The average time to recurrence after resection was 18 months (16.5 months in the low anterior group vs. 19 months in the abdominoperineal group). Mean survival after recurrence was shorter for the abdominoperineal (3.4 months) as compared to the low anterior group (9.5 months) (P = .10). The overall median survival was 21 months (range 0-75 months) in both groups, and 38 patients were alive. Risk factors for recurrence were Dukes C lesions in patients who had a low anterior resection (8/18 or 44% recurrence) and poor histologic differentiation in patients who had either operation (3/6 or 50% recurrence).
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Vlasak JW,Wagner D,Passaro E Jr,Wilson SEdoi
10.1002/jso.2930410409subject
Has Abstractpub_date
1989-08-01 00:00:00pages
236-9issue
4eissn
0022-4790issn
1096-9098journal_volume
41pub_type
杂志文章abstract:BACKGROUND:Immunoreactivity for p53 tumor suppressor gene product is commonly found in human malignancies and some premalignant lesions, but its role in cancer development and its value as a marker of tumor biologic behavior is still unclear. OBJECTIVES:This study was undertaken to assess p53 immunoexpression in esoph...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199705)65:1<3::aid-jso2>3.
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:One of the reasons for the poor prognosis of pancreatic carcinoma is the difficulty of obtaining an early diagnosis of pancreatic carcinoma. One possibility is the application of radioimmunoscintigraphy using radiolabeled monoclonal antibodies (Mabs). METHODS:We labeled chimeric (human/mouse) Fab fragments ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10311
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Little data regarding the selection of nonsurgical therapies for localized intrahepatic cholangiocarcinoma (ICC) are available. METHODS:A cohort of nonsurgically managed patients with American Joint Commission on Cancer clinical stage I/II ICC in the United States from 2004 to 2013 were identified in the Na...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25736
更新日期:2019-12-01 00:00:00
abstract::Reconstructive procedures following chest wall resection pose a special surgical challenge. With modern surgical technique, a wide range of reconstructive options are at the surgeon's disposal and, hence it is imperative that the appropriate procedure be selected in a given patient. A total of 64 patients underwent re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930550311
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Open surgery for hilar cholangiocarcinoma (HCCA) has already been widely reported and analyzed. However, the laparoscopic technique for treating HCCA remains controversial because of the lack of radicality and poor assessment of the resectability of hilar structures without direct palpation. The aim of this ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25739
更新日期:2019-12-01 00:00:00
abstract::The complications of percutaneous intraarterial infusion chemotherapy of the head-and-neck-cancer patient has dampened enthusiasm for this approach. A totally implantable infusion pump system circumvents many of these complications and will in the long term enhance the opportunity to expand upon the advantages of infu...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930210213
更新日期:1982-10-01 00:00:00
abstract:OBJECTIVE:Significant controversy exists concerning the factors affecting survival after secondary cytoreduction (SCR) in recurrent ovarian cancer. This study aims to identify factors independently associated with survival after SCR. METHODS:We retrospectively retrieved 39 patients with recurrent ovarian cancer. All p...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21686
更新日期:2010-11-01 00:00:00
abstract::The clinicopathologic features of a case of malignant Brenner tumor with bilateral ovarian involvement are described. The tumor was apparently confined within the ovaries at initial laparotomy. However, multiple skeletal metastases developed 4 months later and the patient died of the disease 6 months after diagnosis. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260312
更新日期:1984-07-01 00:00:00
abstract::Superficially metastatic melanoma still represents a challenging situation for oncologists and a distressing condition for patients. In this circumstance, local treatment by electrochemotherapy, that is, the combination of brief permeabilizing electric pulses with a low‐toxicity anticancer drug, can be a valuable trea...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23512
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To compare the local recurrence rate and overall survival between patients with circumferential resection margin (CRM) involvement by direct tumor spread and by a tumor within a lymph node. METHODS:A total of 776 patients diagnosed with rectal cancer underwent rectal resection. Patients with CRM involvement by...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25252
更新日期:2018-12-01 00:00:00
abstract::Prevention of cancer is now divided into primary and secondary prevention. Primary prevention is that set of interventions that keeps a cancerous process from ever developing and includes health counseling and education, environmental controls. and product safety as examples. Secondary prevention is that set of interv...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930180302
更新日期:1981-01-01 00:00:00
abstract::The serum copper/zinc ratio was measured in 44 patients bearing primary large bowel malignancies. Measurements were repeated following removal of the primary tumour and again at the time of development of clinical evidence of cancer recurrence in order to evaluate the clinical value of the ratio to accurately reflect ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930210407
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND:Increased activity of Src has been found in several human cancers, and often is associated with poor clinical outcome. The present study aimed to determine whether Src activity is increased in gastrointestinal stromal tumors (GIST), and whether it correlates with established tumor or patient characteristics ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23544
更新日期:2014-05-01 00:00:00
abstract::Remote access approaches for thyroid surgery using surgical incisions placed outside the neck, including the axillary, chest and the retro-auricular region have gained interest due to the social stigmatization of young females with a visible neck scar. These novel approaches have been reported to be safe and feasible ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23955
更新日期:2015-09-01 00:00:00
abstract::A patient-specific 3-dimensional printed model (3DPM) of a woman with breast cancer was created. Mastectomy was favored as BCS would necessitate significant breast size alteration due to the extent of disease. After review of the 3D printed model, the patient and surgeon agreed on breast-conserving surgery. Use of pat...
journal_title:Journal of surgical oncology
pub_type:
doi:10.1002/jso.25680
更新日期:2019-11-01 00:00:00
abstract::Dramatic improvements in morbidity and mortality rates following liver resections have been reported in the past decade. Consequently, the indications for hepatectomy are becoming more liberal. Many techniques of liver resection with or without vascular clamping have been reported with excellent clinical results. Tota...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/(sici)1096-9098(199909)72:1<50::aid-jso14>
更新日期:1999-09-01 00:00:00
abstract::Sentinel lymph node (sN) biopsy has gained special attention among surgical and medical oncologists as it represents an accepted technique for detecting occult nodal disease in regional lymph nodes of patients with melanoma and breast cancer. The histopathologic examination of the sN may well predict regional lymph no...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20031
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Proper tip position is a major determinant of totally implantable venous access device (TIVAD) outcome. The aim of this study is to analyze the potential utilization of intravenous electrocardiography (IV-ECG) to help inexperienced operators for TIVAD placement. PATIENTS AND METHODS:This is a retrospective,...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.23000
更新日期:2012-06-15 00:00:00
abstract::There are a number of retroperitoneal pathologies that may be confused with adrenal tumors. It is important to suspect and recognize these conditions as their management and work up might be different than adrenal tumors. This review will go in to the differential diagnosis and unique features of these conditions. A m...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23133
更新日期:2012-10-01 00:00:00
abstract::The majority of patients with pulmonary metastases from primary soft tissue sarcomas have peripheral lesions that can be removed by wedge excision. A subset of these patients, however, present with, or develop, clinically significant endobronchial metastases. These patients require a preoperative evaluation that inclu...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930320305
更新日期:1986-07-01 00:00:00
abstract:OBJECTIVE:To compare outcomes between thoracoscopic and thoracotomy lobectomy for patients with cN0-pN2 NSCLC. METHODS:One hundred eighty-two cN0 patients (including 29 pN2) underwent VATS lobectomy between September 2006 and December 2009, and 204 cN0 patients (including 47 pN2) underwent thoracotomy lobectomy betwee...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23104
更新日期:2012-09-15 00:00:00
abstract::Twelve women who developed breast cancer at the site of old surgical scars in the breast are presented. Six had had former breast biopsies, 3 drainage of breast abscesses, and 3 developed breast cancer in old thoracotomy scars transversing the breast. The combination of trauma as an oncogen and scar tissue as a functi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930080606
更新日期:1976-01-01 00:00:00
abstract::Little information is available regarding acute upper gastrointestinal bleeding as a presenting sign of gastric carcinoma. Of 427 patients with gastric cancer, 36 (8.4%) underwent early endoscopy due to hematemesis. The hemorrhage was self-limited in 16 patients (44.4%), most of whom underwent elective surgery. Twenty...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930360212
更新日期:1987-10-01 00:00:00
abstract:AIM:To evaluate the efficacy of stereotactic body radiation therapy (SBRT) in small hepatocellular carcinoma (HCC) patients. METHODS:From March 2009 to April 2015, we treated 132 small HCC patients with SBRT. Eligibility criteria included longest tumor diameter ≤5.0 cm; Child-Turcotte-Pugh (CTP) Class A or B; unfeasib...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24128
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In highly selected patients with peritoneal carcinomatosis, cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) can be an aggressive but worthwhile treatment regimen. Resection of the rectosigmoid is frequently performed with CRS. The aim of the study wa...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25189
更新日期:2018-09-01 00:00:00
abstract::Patients with primary squamous cell epitheliomas of the oral cavity, pharynx, and larynx were stratified according to stage and site and randomized to receive either intratumoral immunotherapy with Corynebacterium parvum followed 2 weeks later by surgery and postoperative C parvum for 2 years or surgery alone. There w...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/jso.2930280215
更新日期:1985-02-01 00:00:00
abstract::This article reviews immediate and delayed breast reconstruction with prosthetic implants, and the effect of irradiation therapy. Despite widespread use of breast conserving surgery for early breast cancer, many breast cancer patients still undergo mastectomy. Some of these patients choose breast reconstruction. Over ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20484
更新日期:2006-11-01 00:00:00
abstract::In settings when it is biologically plausible that some patients are cured after definitive treatment, cure models present an alternative to conventional survival analysis. Cure models can inform on the group of patients cured, by estimating the probability of cure, and identifying factors that influence it; while sim...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23411
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) can offer long-term survival to patients with resectable peritoneal metastasis (PM) from colorectal cancer (CRC), a condition with otherwise dismal prognosis. This study describes short- and long-term outcome in ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24290
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:The median survival for patients with stage IV metastatic melanoma is usually limited to approximately 1 year. In the case of liver metastasis, resection and ablation can achieve long-term survival. This study aimed to describe the outcomes after liver resection or ablation for metastatic melanoma to the liv...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23929
更新日期:2015-06-01 00:00:00