New fields of application of the sentinel lymph node biopsy in the pathologic staging of solid neoplasms: review of literature and surgical perspectives.

Abstract:

:Sentinel lymph node (sN) biopsy has gained special attention among surgical and medical oncologists as it represents an accepted technique for detecting occult nodal disease in regional lymph nodes of patients with melanoma and breast cancer. The histopathologic examination of the sN may well predict regional lymph node status in order to define the most suitable loco-regional and systemic treatment. Recently, this technique has also been applied to other solid tumor types such as gynecologic and urologic malignancies, squamous head and neck cancer, thyroid cancer, non-small-cell lung cancer, Merkel cell carcinoma, and gastric cancer. The aim of this literature review is to define the rationale of sN biopsy in these tumor sites, the most effective procedure for sN detection, and the accuracy of the sN in predicting regional nodal status, as well as the surgical perspectives of sN biopsy application.

journal_name

J Surg Oncol

authors

Gipponi M,Solari N,Di Somma FC,Bertoglio S,Cafiero F

doi

10.1002/jso.20031

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

171-9

issue

3

eissn

0022-4790

issn

1096-9098

journal_volume

85

pub_type

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