Preoperative systemic inflammatory markers are prognostic indicators in recurrent adrenocortical carcinoma.

Abstract:

BACKGROUND:Recurrent adrenocortical carcinoma (ACC) has a poor prognosis with minimal clinical and biochemical factors to guide management. The aim of this study was to evaluate the prognostic significance of systemic inflammatory response in patients with recurrent ACC. METHODS:Patients who underwent resection for recurrent ACC were retrospectively analyzed. Preoperative neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio (LMR), and mean platelet volume were calculated. RESULTS:Twenty-five patients (age at operation 52.2 ± 9.5 years) were identified. We observed a statistically significant shorter disease-specific survival (DSS) in patients with LMR less than 4 (41 ± 7.4 months vs 71 ± 12.3, P = .023) and male sex (26.6 ± 4.2 months vs 57.6 ± 9.5 months, P = .079), while time-to-recurrence (TTR) less than 12 months (40 ± 7.7 months vs 70.3 ± 13.1 months, P = .059) had a trend on univariate analysis for worse DSS. On multivariable analysis, LMR < 4 (hazard ratio [HR] 4.18; 95% confidence interval [CI]: 1.18-14.76; P = .027) and TTR less than 12 months (HR 2.77 95% CI: 1-7.62; P = .049) were found to be significantly associated with worse DSS. CONCLUSION:Preoperative LMR greater than 4 and TTR greater than 12 months are associated with longer DSS. Patients with LMR greater than 4 and TTR greater than 12 months may benefit from a more aggressive therapeutic approach and may require less frequent surveillance.

journal_name

J Surg Oncol

authors

Gaitanidis A,Wiseman D,El Lakis M,Nilubol N,Kebebew E,Patel D

doi

10.1002/jso.25760

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

1450-1455

issue

8

eissn

0022-4790

issn

1096-9098

journal_volume

120

pub_type

杂志文章
  • The efficacy of systematic lymph node dissection in advanced epithelial ovarian cancer during interval debulking surgery performed after neoadjuvant chemotherapy.

    abstract:BACKGROUND AND OBJECTIVE:The therapeutic role of systematic lymph node dissection (LND) remains unclear in advanced epithelial ovarian cancer (EOC), especially during interval debulking surgery (IDS) performed after neoadjuvant chemotherapy (NAC). We analyzed the therapeutic and prognostic roles of systematic LND in ad...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24669

    authors: Eoh KJ,Yoon JW,Lee I,Lee JY,Kim S,Kim SW,Kim YT,Nam EJ

    更新日期:2017-09-01 00:00:00

  • Acute appendicitis as a sign of a colorectal carcinoma.

    abstract::The relationship of acute appendicitis occurring previous to cancer in colon and rectum was studied in the consecutive records of 561 patients, of 40 years of age and older, operated upon with an appendectomy because of acute appendicitis. Sixteen (2.9%) of these patients were readmitted within three years because of ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930200105

    authors: Arnbjörnsson E

    更新日期:1982-05-01 00:00:00

  • Treatment of gastric cancer with peritoneal carcinomatosis by cytoreductive surgery and HIPEC: a systematic review of survival, mortality, and morbidity.

    abstract::Gastric cancer with peritoneal carcinomatosis has an extremely poor prognosis, which may be improved with cytoreductive surgery (CRS) combined with heated intraperitoneal chemotherapy (HIPEC). We systematically reviewed the literature regarding the efficacy of CRS + HIPEC in these patients. Electronic databases were s...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.22017

    authors: Gill RS,Al-Adra DP,Nagendran J,Campbell S,Shi X,Haase E,Schiller D

    更新日期:2011-11-01 00:00:00

  • Asymptomatic retroperitoneal dermoid cyst (benign cystic teratoma) in a 64-year-old male: an autopsy case report.

    abstract::A primary retroperitoneal dermoid cyst (benign cystic teratoma) is described in a 64-year-old male, who died postoperatively of a leaking grafted abdominal aortic aneurysm. The asymptomatic tumor, measuring 12 cm in greatest diameter, showed an extensive sclerosing lipogranulomatous reaction in its wall and wide-sprea...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930140102

    authors: Honoré LH

    更新日期:1980-01-01 00:00:00

  • Diagnosis and treatment of primary and recurrent retroperitoneal liposarcoma.

    abstract::We retrospectively reviewed 16 patients in whom primary retroperitoneal liposarcoma was diagnosed and treated. These patients were classified according to the first definitive surgical procedure employed: complete excision with or without radiotherapy; partial excision followed by radiotherapy; only biopsy of tumor fo...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930470110

    authors: Witz M,Shapira Y,Dinbar A

    更新日期:1991-05-01 00:00:00

  • Identification of a single nucleotide polymorphism in the MMP-1 promoter in chondrosarcoma.

    abstract::Matrix metalloproteinases (MMPs) are a group of at least 26 enzymes that facilitate cellular invasion via the degradation of the extracellular matrix. Specifically, the ability to degrade collagen types III and I is important in tumor invasion and metastasis. Over expression of the MMP-1 gene has been shown to correla...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20100

    authors: Dickey ID,Scully SP

    更新日期:2004-09-01 00:00:00

  • Autologous diaphragm reconstruction with the pedicled latissimus dorsi flap.

    abstract::The latissimus dorsi (LD) muscle has been previously described to repair diaphragmatic defects, but as a "reverse" flap, relying on secondary blood supply from the perforating lumbar vessels rather than primary inflow from the dominant thoracodorsal artery. We report resection of a retroperitoneal synovial sarcoma, wi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20317

    authors: McConkey MO,Temple CL,McFadden S,Temple WJ

    更新日期:2006-09-01 00:00:00

  • Lung resection for metastatic sarcomas: total survival from primary treatment.

    abstract::The results of surgical management of 63 cases of pulmonary metastases from bone and soft tissue sarcomas, admitted at the Istituto Nazionale Tumori of Milan, between 1970 and 1987, are reviewed in this paper. To estimate the relative impact of metastasectomy on the overall performance of treatment, survival curves we...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930400414

    authors: Pastorino U,Valente M,Gasparini M,Azzarelli A,Santoro A,Alloisio M,Ongari M,Tavecchio L,Ravasi G

    更新日期:1989-04-01 00:00:00

  • Outcome after reconstruction of proximal femoral tumors: A systematic review.

    abstract::Tumor resection followed by reconstruction with a proximal femoral endoprosthesis or an allograft-prosthesis composite are the two main alternatives for treatment of proximal femoral malignancies. This review describes the revision rate, implant survival, limb salvage rate, and function. Overall revision rates are hig...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,meta分析

    doi:10.1002/jso.25297

    authors: Janssen SJ,Langerhuizen DWG,Schwab JH,Bramer JAM

    更新日期:2019-01-01 00:00:00

  • Therapeutic value of lymph node dissection for esophageal squamous cell carcinoma after neoadjuvant chemotherapy.

    abstract:BACKGROUND AND OBJECTIVES:The optimal extent of lymphadenectomy in patients with esophageal cancer is controversial. This study aimed to examine the therapeutic value of lymph node (LN) dissection for each LN station in patients with esophageal squamous cell carcinoma (ESCC) who receive neoadjuvant chemotherapy. METHO...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23965

    authors: Miyata H,Yamasaki M,Makino T,Miyazaki Y,Takahashi T,Kurokawa Y,Nakajima K,Takiguchi S,Mori M,Doki Y

    更新日期:2015-07-01 00:00:00

  • When to start an aromatase inhibitor: now or later?

    abstract::Among women who have undergone surgery for breast cancer, the risk of recurrence, especially distant metastases, peaks 1-2 years postsurgery. Recent clinical trial evidence suggests that initial adjuvant therapy with an aromatase inhibitor (AI) can reduce this early risk of recurrence. According to the recently update...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.21801

    authors: Doughty JC

    更新日期:2011-06-01 00:00:00

  • Robot-assisted retroperitoneal lymph node dissection in testicular cancer.

    abstract::Robotic surgical techniques are now being applied in the setting of retroperitoneal lymphadenectomy (RPLND) for testicular cancer. While laparoscopic RPLND has not been widely accepted, reports of robot assisted RPLND (RARPLND) are emerging. This manuscript will review the application of RPLND for testicular cancer, e...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.24018

    authors: Abdul-Muhsin HM,L'esperance JO,Fischer K,Woods ME,Porter JR,Castle EP

    更新日期:2015-12-01 00:00:00

  • Biodistribution of monoclonal antibody A7 and its F(ab')2 fragment in athymic nude mice bearing human pancreatic carcinoma.

    abstract::Xenografts of a human pancreatic carcinoma cell line, HPC-YS, which reacted with the monoclonal antibody (MAb) A7, were used to investigate the in vivo localization of radioiodinated MAb A7 after intraperitoneal injection. MAb A7 localized to the tumor 4 days and 8 days after injection with a tissue/blood ratio of 1.4...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930500309

    authors: Otsuji E,Yamaguchi T,Yamaoka N,Yamaguchi N,Imanishi J,Takahashi T

    更新日期:1992-07-01 00:00:00

  • Mastectomy in the management of patients with inflammatory breast cancer.

    abstract::Inflammatory carcinoma of the breast is rare and lethal. Since the early 1940s, operation except for biopsy has been contraindicated in patients with inflammatory breast cancer. Results with radiotherapy alone and with radiotherapy and chemotherapy are reviewed. Results of treating patients with initial chemotherapy a...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930230408

    authors: Morris DM

    更新日期:1983-08-01 00:00:00

  • Spontaneous regression of breast carcinoma: follow-up report and literature review.

    abstract::A case of spontaneous complete regression of metastatic breast carcinoma (malignant pleural effusion and bone metastases) with previously reported from M. D. Anderson Hospital and Tumor Institute. The patient did not receive any form of hormonal manipulation or systemic chemotherapy. This patient has now relapsed afte...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930190107

    authors: Ross MB,Buzdar AU,Hortobagyi GN,Lukeman JM

    更新日期:1982-01-01 00:00:00

  • The role and value of surgery in metastatic renal adenocarcinoma: a retrospective clinical study of 106 nephrectomized cases.

    abstract::The results of treatment of 106 consecutive nephrectomized cases with metastatic renal adenocarcinoma were analyzed. Over 50% of the patients were dead at 1 year and more than 80% at 2 years from the first metastases. The corresponding 5-year survival rate was 7.3%. Fourteen patients demonstrated a response to radioth...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930260213

    authors: Appelqvist P

    更新日期:1984-06-01 00:00:00

  • Hexamethylmelamine and melphalan as salvage therapy in advanced ovarian carcinoma.

    abstract::Ten patients with advanced ovarian carcinoma were treated with hexamethylmelamine and melphalan after failing first-line combination chemotherapy. In eight patients residual disease was evident only at second-look laparotomy. Surgical debulking was accomplished in four patients but only two patients had residual disea...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930210305

    authors: Tempero MA,Kessinger A

    更新日期:1982-11-01 00:00:00

  • Experimental study and clinical application of a single-row suturing esophagogastrostomy.

    abstract::A single-row suturing anastomosis (SRA) for an esophagogastrostomy was experimentally investigated in dogs. SRA not only shortened operating time, but also led to better pathological results when compared with double-row suturing anastomosis. Wide-brim suturing and equal distance between the sutures, providing increas...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930430309

    authors: Gao SZ,Wang TS,Yao Z,Cheng BC,Tu ZF,Ling DM,Peng SY

    更新日期:1990-03-01 00:00:00

  • Survival analysis of patients with chondrosarcomas of the pelvis.

    abstract:BACKGROUND:Studies for patients with pelvic chondrosarcomas are limited. This study determines the outcome of patients with pelvic chondrosarcomas, and whether there is any association with tumors' grade, type, stage, margins and pelvic location. MATERIALS AND METHODS:We retrospectively studied 215 patients with pelvi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23351

    authors: Mavrogenis AF,Angelini A,Drago G,Merlino B,Ruggieri P

    更新日期:2013-07-01 00:00:00

  • Proton radiation therapy for head and neck cancer.

    abstract::Due to the close spatial relationship of head and neck and skull base tumors to numerous normal anatomical structures, conventional photon radiation therapy can be associated with significant acute and long-term treatment-related toxicities. Superior dose localization properties of proton radiation therapy allow small...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.21013

    authors: Chan AW,Liebsch NJ

    更新日期:2008-06-15 00:00:00

  • Biological reconstruction using massive bone allograft with intramedullary vascularized fibular flap after intercalary resection of humeral malignancy.

    abstract:BACKGROUND:Reconstruction after excision of the humeral malignancy is a challenging issue for the reconstructive surgeon. The combined use of a fibular flap and allograft can provide a reliable reconstructive option. This article describes the authors' experience with this technique for the treatment of segmental bone ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21922

    authors: Li J,Wang Z,Pei GX,Guo Z

    更新日期:2011-09-01 00:00:00

  • Melanoma patterns of care in Ontario: A call for a strategic alignment of multidisciplinary care.

    abstract:BACKGROUND AND OBJECTIVES:Variability in melanoma management has prompted concerns about equitable and timely treatment. We investigated patterns of melanoma diagnosis and treatment using population-level data. METHODS:Patients with invasive cutaneous melanoma were identified retrospectively from the Ontario Cancer Re...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24936

    authors: Look Hong NJ,Cheng SY,Baxter NN,Wright FC

    更新日期:2018-03-01 00:00:00

  • Transsternal thoracotomy for bilateral pulmonary metastasis.

    abstract::Advances in the surgical treatment of primary malignancies and the recent chemotherapy have led to an expansion of the surgical treatment of metastatic lung tumors. However, multiple pulmonary metastases are often found and may affect both lungs. It is difficult to reach tumors in the posterior parts of the lung when ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930500210

    authors: Shimizu N,Ando A,Matsutani T,Maruyama S,Date H,Teramoto S

    更新日期:1992-06-01 00:00:00

  • Verrucous carcinoma of the foot.

    abstract::A 50-year-old man presented with verrucous carcinoma on the sole of the foot. This unusual tumor, also called an epithelioma cuniculatum plantare, was successfully treated employing wide surgical excision. ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930140407

    authors: Schwartz RA,Burgess GH

    更新日期:1980-01-01 00:00:00

  • Nuclear translocation of HER-4/c-erbB-4 is significantly correlated with prognosis of esophageal squamous cell carcinoma.

    abstract:BACKGROUND:HER family is an attractive target for the treatment of esophageal cancer. The clinical relevance of HER-4 has not been yet characterized. METHODS:The expression of HER-4 was immunohistochemically examined in 61 surgically resected esophageal squamous cell carcinomas (ESCC), and the prognostic significance ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20892

    authors: Xu S,Kitayama J,Yamashita H,Souma D,Nagawa H

    更新日期:2008-01-01 00:00:00

  • Metastatic disease in patients with newly diagnosed malignant melanoma.

    abstract::In patients with stage I Clark's level III and IV malignant melanoma (MM), recurrence rates of 30-60% can be expected after resection of the primary lesion. If metastatic disease could be detected early and treated in such patients, survival might be prolonged. Ninety patients (37 males and 53 females) with newly diag...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930350304

    authors: Zartman GM,Thomas MR,Robinson WA

    更新日期:1987-07-01 00:00:00

  • Assessing cosmetic results after breast conserving surgery.

    abstract::"Taking less treating better" has been one of the major improvements of breast cancer surgery in the last four decades. The application of this principle translates into equivalent survival of breast cancer conserving treatment (BCT) when compared to mastectomy, with a better cosmetic outcome. While it is relatively e...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.23596

    authors: Cardoso MJ,Oliveira H,Cardoso J

    更新日期:2014-07-01 00:00:00

  • Yttrium-90 radiation segmentectomy for hepatic metastases: A multi-institutional study of safety and efficacy.

    abstract:BACKGROUND AND OBJECTIVES:This study assessed the outcomes of Yttrium-90 (90 Y) radiation segmentectomy for hepatic metastases unamenable to resection or ablation. MATERIALS AND METHODS:Over 6 years, 36 patients with 53 tumors underwent segmental radioembolization. Patients were not candidates for surgical resection o...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jso.26223

    authors: Padia SA,Johnson GE,Agopian VG,DiNorcia J,Srinivasa RN,Sayre J,Shin DS

    更新日期:2021-01-01 00:00:00

  • Neoadjuvant chemotherapy or chemoradiotherapy for adenocarcinoma of the esophagus.

    abstract:BACKGROUND:The optimal treatment strategy for patients with esophageal adenocarcinoma (EAC) remains undetermined. This study compared outcomes in patients undergoing neoadjuvant chemotherapy (nCT) and neoadjuvant chemoradiotherapy (nCRT) for EAC. METHODS:Patients who underwent nCT or nCRT followed by surgery for EAC w...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25089

    authors: Visser E,Edholm D,Smithers BM,Thomson IG,Burmeister BH,Walpole ET,Gotley DC,Joubert WL,Atkinson V,Mai T,Thomas JM,Barbour AP

    更新日期:2018-06-01 00:00:00

  • Fractal heterogeneity of peripheral blood flow: implications for hematogenous metastases.

    abstract:BACKGROUND AND OBJECTIVES:To determine how inhomogeneities in blood perfusion might affect the number of metastases that develop within an individual with cancer. METHODS:Experiments with lung metastases in mice, involving 320 treatment groups and 3165 mice, were reviewed. Inhomogeneities in the distribution of metast...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/1096-9098(200006)74:2<116::AID-JSO7>3.0.CO

    authors: Kendal WS

    更新日期:2000-06-01 00:00:00