Abstract：
BACKGROUND AND OBJECTIVES:Variability in melanoma management has prompted concerns about equitable and timely treatment. We investigated patterns of melanoma diagnosis and treatment using population-level data. METHODS:Patients with invasive cutaneous melanoma were identified retrospectively from the Ontario Cancer Registry (2003-2012) and deterministically linked with administrative databases to identify incidence, disease characteristics, geographic origin, and multimodal treatment within a year of diagnosis. Melanoma treatment was categorized as inadequate or adequate based on multidisciplinary clinical algorithms. Multivariable logistic regression was used to model factors associated with treatment adequacy. RESULTS:From 2003 to 2012, 22 918 patients with invasive melanoma were identified with annual age/sex standardized incidence rates of 11.7-14.3/100 000 for females and 13.4-15.9/100 000 for males. Melanoma occurred at median age of 62 and primarily on extremities (43.9%). Within 1 year after diagnosis, 86.7% of patients received surgery as primary therapy. A total of 2312 (10.6%) patients received inadequate or no treatment after diagnosis. Receiving adequate treatment was associated with consultation with dermatology (OR 1.92, CI 1.71-2.14), plastic surgery (OR 4.80, CI 4.32-5.34), or general surgery (OR 2.15, CI 1.94-2.38). CONCLUSIONS:Significant variation exists in melanoma management and nearly one in nine patients is inadequately treated. Referral to sub-specialized providers is critical for ensuring appropriate care.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Look Hong NJ,Cheng SY,Baxter NN,Wright FCdoi
10.1002/jso.24936subject
Has Abstractpub_date
2018-03-01 00:00:00pages
597-617issue
4eissn
0022-4790issn
1096-9098journal_volume
117pub_type
杂志文章abstract：:A case of renal cell carcinoma arising in a horseshoe kidney and presenting with a pathologic fracture of humerus is reported. Relevant literature is discussed. ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930260116
更新日期：1984-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Reports of clinicopathological features and prognosis in patients with mucinous gastric carcinoma (MGC) are conflicting. The aim was to describe the clinicopathological features and prognosis of patients with MGC in comparison with nonmucinous gastric carcinoma (NMGC). METHODS:We reviewed the...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.21533
更新日期：2010-07-01 00:00:00
abstract：:Intraperitoneal (IP) cisplatin administered at the time of intraabdominal malignancies such as gastric cancer may prevent or delay intraabdominal recurrence. Perioperative IP cisplatin raises concerns regarding systemic toxicity and retardation of wound healing. Systemic cisplatin toxicity may be reduced by administer...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930520415
更新日期：1993-04-01 00:00:00
abstract：:The Author describes criteria for selection of patients who might be eligible for entry into a clinical trial of definitive Radiation Therapy for adenocarcinoma of the pancreas. Most emphasis is placed on careful surgical staging, target volume and location, and the use of bypass procedures when appropriate. ...
journal_title：Journal of surgical oncology
pub_type： 临床试验,杂志文章
doi：10.1002/jso.2930070208
更新日期：1975-01-01 00:00:00
abstract：:We report a case of transitional cell carcinoma of the anterior male urethra. Unlike squamous cell carcinoma of the anterior urethra, which usually requires partial penectomy, transitional cell carcinoma of this location can be managed with conservative local resection and preservation of the penis. Possible explanati...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930210212
更新日期：1982-10-01 00:00:00
abstract：OBJECTIVE:Gastrointestinal stromal tumors (GISTs) occur rarely in the duodenum. The characteristics of duodenal GIST have not been well clarified. The aim of this study is to clarify the characteristics and surgical prognosis of patients with primary duodenal GIST. METHODS:Data of patients with surgically treated prim...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.21378
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Use of hospice services among patients with pancreatic cancer following pancreatic resection remains unknown. METHODS:Patients with pancreatic cancer who underwent resection were identified in the Medicare Standard Analytic Files. Outcomes included overall hospice use, early hospice enrollment (≥4 weeks bef...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.25623
更新日期：2019-09-01 00:00:00
abstract：:Fibronectin (FN) was investigated in 75 stroma from lung adenocarcinoma patients. Distribution of FN was classified into three patterns based on immunohistochemical evidence: dense, moderate, and sparse distribution. The incidence of the sparse pattern in both stage I and stage III disease was significantly greater in...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930430208
更新日期：1990-02-01 00:00:00
abstract：BACKGROUND:HER family is an attractive target for the treatment of esophageal cancer. The clinical relevance of HER-4 has not been yet characterized. METHODS:The expression of HER-4 was immunohistochemically examined in 61 surgically resected esophageal squamous cell carcinomas (ESCC), and the prognostic significance ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.20892
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The genetic alterations involved in extrahepatic bile duct (EHBD) cancer are poorly understood. Our aim was to identify aberrations of the K-ras, p53, and APC genes in EHBD cancer. METHODS:We investigated aberrations of these genes in 52 EHBD cancers using polymerase chain reaction (PCR) sing...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/(sici)1096-9098(200003)73:3<158::aid-jso9>
更新日期：2000-03-01 00:00:00
abstract：:A patient-specific 3-dimensional printed model (3DPM) of a woman with breast cancer was created. Mastectomy was favored as BCS would necessitate significant breast size alteration due to the extent of disease. After review of the 3D printed model, the patient and surgeon agreed on breast-conserving surgery. Use of pat...
journal_title：Journal of surgical oncology
pub_type：
doi：10.1002/jso.25680
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Patients chosen for liver resection of colorectal liver metastases are a select group with minimal disease, favorable tumor biology and earlier presentation when compared to unresectable patients. Despite intense preoperative assessments, operative detection of occult unresectable disease is inevitable for a...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.20341
更新日期：2005-10-01 00:00:00
abstract：:The hanging liver maneuver is a useful technique to guide the transection of liver parenchyma by lifting a tape passed between the anterior surface of the inferior vena cava and the liver. Modified hanging liver maneuvers have been described in different types of liver resection. Surgical resection of hilar cholangioc...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.24154
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:There is currently debate about the optimal timing and frequency of mammography follow-up after breast-conserving therapy (BCT). The purpose of this study was to determine if 6-month intervals for the first 2 years following BCT offer benefit over annual screening. METHODS:Three hundred ninet...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.23298
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Although race and socioeconomic status have been shown to affect outcomes in pancreatic ductal adenocarcinoma (PDAC), the impact of rural residence on the delivery of adjuvant therapy (AT) has not been studied. METHODS:Patients with resected PDAC were identified using the National Cancer Data...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.25060
更新日期：2018-06-01 00:00:00
abstract：INTRODUCTION:The number of incidentally discovered adrenal lesions is increasing due to the widespread use of abdominal imaging. Although most incidentalomas are benign, larger suspicious lesions will require adrenalectomy. The aim of this study is to determine the risk of malignancy in patients undergoing surgery for ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.21553
更新日期：2010-10-01 00:00:00
abstract：:Gallbladder adenocarcinoma (GBA) postresection 5-year survival rates are less than 5%, but when histologically confined to the mucosa or submucosa, survival rates of 64% (5 years) and 44% (10 years) have been reported. Whether any other histologic features of GBA have prognostic significance is unknown. This investiga...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930340105
更新日期：1987-01-01 00:00:00
abstract：INTRODUCTION:The ACS-NSQIP surgical risk calculator is an open-access on-line tool that estimates the risk of adverse post-operative outcomes for a wide range of surgical procedures. Wide surgical resection of soft tissue sarcoma (STS) often requires complex reconstructive procedures that can be associated with relativ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.24357
更新日期：2016-10-01 00:00:00
abstract：:Early postoperative intraperitoneal chemotherapy (EPIC) and intraoperative peritoneal hypertermic chemotherapy (IPHC) are used in addition with cytoreductive surgery to treat with curative intent peritoneal carcinomatosis arising from colorectal adenocarcinomas. Three patients with such a disease were treated with per...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.20267
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:The role of postmastectomy radiation therapy (PMRT) after neoadjuvant chemotherapy (NAC) and mastectomy is unclear, especially in patients that have post-treatment tumor negative axillary nodes (ypN0). METHODS:The National Cancer Data Base was used to identify women that had PMRT after NAC and mastectomy fo...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.24551
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:The role of surgical resection in the treatment of patients with metastatic/recurrent gastrointestinal stromal tumors (GIST) is unclear. The aim of this study was to identify preoperative factors associated with oncologic outcomes for recurrent/metastatic GIST after tyrosine kinase inhibitor (TKI) therapy. ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.24988
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Mutation of the KRAS oncogene (mKRAS) in colorectal cancer has been associated with aggressive tumor biology, resistance to epidermal growth factor inhibitors, and decreased overall survival (OS). The aim of the current study was to analyze the association of mKRAS with pathologic complete response (pCR) and...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.26244
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVES:This study investigated disparities in the delivery of definitive therapy for early stage non-small-cell lung cancer (ESNSCLC) between Caucasian (CS) and African American (AA) populations. METHODS:The National Cancer Data Base was queried for AA and CS patients, diagnosed with c stage I Non small cell lung ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.26206
更新日期：2020-12-01 00:00:00
abstract：:The poor outcome associated with surgical resection alone for most patients with locoregional esophageal cancer has generated intensive investigation of combined-modality treatment approaches that include systemic chemotherapy. This review discusses the current role of chemotherapy in the treatment of patients with ad...
journal_title：Journal of surgical oncology
pub_type： 杂志文章,评审
doi：10.1002/jso.20364
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:To evaluate the impact of plasminogen activator (PA) system genes, including urokinase plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms in patients with the cervical neoplasia. METHODS:In total, 336 blood samples were collected...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.23072
更新日期：2012-08-01 00:00:00
abstract：:A 38-year-old woman with early stage invasive breast cancer was treated with wide excision of the tumor, axillary lymph node dissection, and breast irradiation. Three years later, she gave birth to a normal baby. She attempted breast feeding and had full lactation from the untreated breast. The irradiated breast under...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930460214
更新日期：1991-02-01 00:00:00
abstract：:Remote access approaches for thyroid surgery using surgical incisions placed outside the neck, including the axillary, chest and the retro-auricular region have gained interest due to the social stigmatization of young females with a visible neck scar. These novel approaches have been reported to be safe and feasible ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章,评审
doi：10.1002/jso.23955
更新日期：2015-09-01 00:00:00
abstract：:Retroperitoneal sarcomas (RPS) frequently involve major vessels, which either originate from them or secondarily encase or invade them. In this field, major vascular resections result in increased morbidity. However, survival does not seem to be affected by the need for vascular resection or by this higher morbidity. ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章,评审
doi：10.1002/jso.24920
更新日期：2018-01-01 00:00:00
abstract：:Prophylactic intravesical chemotherapy (IVC) reduces recurrence rates of superficial transitional cell carcinoma (TCC) of the urinary bladder. The patient cohort existed of 86 individuals (stage TaN0M0 or T1N0M0) superficial carcinoma of various grades of malignancy. Following initial transuretheral resection or diagn...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930600310
更新日期：1995-11-01 00:00:00
abstract：INTRODUCTION:We sought to validate the commonly used prognostic models and staging systems for intrahepatic cholangiocarcinoma (ICC) in a large multi-center patient cohort. METHODS:The overall (OS) and disease free survival (DFS) prognostic discriminatory ability of various commonly used models were assessed in a larg...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.24759
更新日期：2017-12-01 00:00:00
