Abstract:
:Gallbladder adenocarcinoma (GBA) postresection 5-year survival rates are less than 5%, but when histologically confined to the mucosa or submucosa, survival rates of 64% (5 years) and 44% (10 years) have been reported. Whether any other histologic features of GBA have prognostic significance is unknown. This investigation was conducted to determine if GBA histologic grade correlates with survival. Thirty patients with advanced stage GBA participating in Eastern Cooperative Oncology Group (ECOG) treatment protocol EST-2273 served as the study material. Using glandular tumor grade criteria recommended by others, a panel of 7 ECOG pathologists categorized the GBA as either predominantly low or high histologic grade. Each patient's GBA histologic section measured no less than 1.0 X 1.0 cm. Predominant grade was defined as being that grade present in greater than 75% of the histologic section. Patient survival times by grade were calculated from date of initiation of chemotherapy until date of death. The 13-week low grade GBA patient survival was significantly longer than the 7-week high grade GBA patient survival (p less than 0.01). Stratification of patients by either high or low predominant histologic grade is recommended in future GBA treatment studies.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Johnson LA,Lavin PT,Dayal YY,Geller SA,Doos WG,Cooper HS,Gerber JE,Masse SR,Weiland LH,Moertel CGdoi
10.1002/jso.2930340105subject
Has Abstract,Author List Incompletepub_date
1987-01-01 00:00:00pages
16-8issue
1eissn
0022-4790issn
1096-9098journal_volume
34pub_type
杂志文章abstract::A comparative study of breast cancer was made among black and white populations admitted to two inner-city hospitals from 1971 through 1976, inclusive. There were 306 patients in the study group of which 162 were black and 144 were white. Age, sex, color, duration of illness, different quadrants of breast involved, st...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930150104
更新日期:1980-01-01 00:00:00
abstract:PURPOSE:To present the clinical data of 35 patients with T3 unresectable hepatocellular carcinoma (HCC) that were treated with (90)Y with the specific intent of downstaging to resection, radiofrequency ablation (RFA) candidate, United Network for Organ Sharing (UNOS) stage T2 or liver transplantation. MATERIALS AND ME...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20609
更新日期:2006-12-01 00:00:00
abstract::A longitudinal osteotomy of lateral sacrum for malignant iliac tumors using modified threadwire saw is conducted. This procedure issignificantly wide, rapid and safe. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20646
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Certain tumor-related factors like thickness increases the risk of nodal metastasis and may affect survival in patients with oral tongue cancers. The objective of this study is to identify those tumor-related prognostic predictors that can potentially influence decision for adjuvant radiothera...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23583
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the effect of age on CAL and its associated mortality. METHODS:Data were derived from the Dutch ColoRectal Audit. All patients undergoing resection for colorectal cancer in the Netherlands between January 2011 and December 2016 were included. Univariable and multivar...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25108
更新日期:2018-07-01 00:00:00
abstract::This study comprises 27 cases of male breast cancer treated at the University Hospital from 1966 through 1978. Its incidence was 0.53% of all cancer in males and 3.2% of all mammary cancers. Mean age was 52 years old. Lump in the breast was the commonest presenting feature in all patients followed by skin ulceration i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930160206
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The optimal management of symptomatic advanced peritoneal carcinomatosis of non-gynecologic origin is not defined. Historic controls of surgical efforts report high postoperative mortality and morbidity rates with equivocal palliation. Novel surgical procedures need to be tested in terms of th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10270
更新日期:2003-08-01 00:00:00
abstract::Tumor-associated antigen(s) from a specimen of human malignant melanoma and from spent culture medium of a melanoma cell line were extracted and purified. The incidence of antibody activity to these antigens, in sera from cancer patients with neoplasms of various histologic types, was higher (65--83%) than normal dono...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130112
更新日期:1980-01-01 00:00:00
abstract::Twenty cases of neoplasms in skin and subcutaneous tissue over the breast were reviewed. There were 17 women, from 15 to 70 years of age, and three men, from 25 to 66 years of age. Among the benign skin neoplasms, superficial leiomyoma, granular cell tumor, and eccrine acrospiroma were misdiagnosed clinically as prima...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930310312
更新日期:1986-03-01 00:00:00
abstract::In our previous study on liposome-mediated transfection of the human interferon-beta (HuIFN-beta) gene into subcutaneously implanted human gliomas in nude mice, we found that HuIFN-beta was produced and secreted by the tumor cells and that the growth of solid tumors was completely inhibited. The present study investig...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930590207
更新日期:1995-06-01 00:00:00
abstract::A transplantable mammary adenocarcinoma, grown in Balb/c mice, with a marked enhancement in its draining lymph node metastatic ability (MM3LN), was obtained through an in vivo procedure from a variant tumor moderately metastatic to lymph nodes (MM3). Both MM3 and MM3LN presented a similar latency and tumor growth rate...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930450312
更新日期:1990-11-01 00:00:00
abstract:BACKGROUND:The object of the current study was to review the outcomes of hepatic resection for hepatocellular carcinoma (HCC) ≥ 10 cm. METHODS:Between 1995 and 2007, fifty-three patients with HCC ≥ 10 cm underwent hepatic resection, and clinical data were compared to those of patients with non-surgical treatment (n = ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21931
更新日期:2011-09-01 00:00:00
abstract::A case of synovial sarcoma in the abdominal wall of a 50-year-old Iraq female is reported. The ultrastructure of the tumor has been studied. Eight other cases of synovial sarcoma in the abdominal wall which reported in the English literature up to 1978 have been reviewed. Synovial sarcomas in the abdominal wall tend t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930180403
更新日期:1981-01-01 00:00:00
abstract::Staging of bladder tumors is based primarily on the depth of tumor invasion (T-category). Stage is important to treatment planning and prognosis. The problem is that clinical evaluation by T-category alone often understages the pathologic extent of disease and does not reliably predict treatment results. The current a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930510403
更新日期:1992-12-01 00:00:00
abstract::The clinical records and treatment results of 163 patients with Hodgkin's disease, who were seen at Ellis Fischel State Cancer Hospital (EFSCH) between 1940 and 1971, were reviewed and analyzed. More than 200 clinical and histological variables were recorded for each case of Hodgkin's disease, including details of rad...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930070402
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Accumulating epidemiological and molecular evidence suggests that inflammation is an important component in the etiology of PCa. Macrophage migration inhibitory factor (MIF) plays an important role in the pro- and anti-inflammatory response to infection. This study is aimed at investigating th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21304
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Radical surgery is the only curative treatment for carcinoma of gallbladder. This study aimed to evaluate the outcome of patients with carcinoma of gallbladder managed in a single institution over 16 years. METHODS:From April 1988 to November 2003, 86 patients (29 males, 57 females) were diagnosed to have c...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20885
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Rates of nonoperative management of acute appendicitis and appendiceal adenocarcinoma have increased over a decade, but the presentation and outcomes of appendiceal adenocarcinoma over this period is not well-characterized. METHODS:Patients with surgically resected Stage I-III appendiceal adenocarcinoma wer...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26295
更新日期:2020-11-10 00:00:00
abstract:BACKGROUND:Giant cell tumor of bone (GCTB) is an aggressive benign bone tumor with poor prognosis whose neoplastic component is stromal cells (SCs). Tumor stem-like cells (TSCs) have been demonstrated as precursors for tumor genesis and growth. The aim of this study is to identify TSCs in GCTB. METHODS:Stro-1(+) and S...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23151
更新日期:2012-12-01 00:00:00
abstract::Carcinoma of the lung should be considered in the search for an unknown primary lesion when there is evidence of cervical lymph node involvement. Of 1,686 patients with a final diagnosis of bronchogenic carcinoma seen during a 10-year period at the University of Louisville Hospitals, 26 presented one or more clinicall...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930090513
更新日期:1977-01-01 00:00:00
abstract::Evaluation of 135 consecutive patients was made for breast masses by the same surgeon and the patients were subsequently referred for ultrasound mammography of the breast after xeromammography revealed a "dysplastic" (DY) pattern only, with no evidence of malignancy. Three patients had carcinoma of the breast detected...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930190203
更新日期:1982-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The study of pathology and prognosis for patients with ovarian tumors of low malignant potential (LMP) has been well documented. The treatment, particularly the secondary surgery, for recurrent disease is less documented. This study was conducted to investigate the role of secondary surgical c...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20280
更新日期:2005-07-01 00:00:00
abstract::Distribution of Leu-7+ cells in cancer tissues and regional lymph nodes was immunohistochemically examined to estimate the role of NK cells in colorectal cancer patients. Leu-7+ cells were rarely observed both in the primary and distant metastatic lesions, but the number of these cells was large in the germinal center...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930450406
更新日期:1990-12-01 00:00:00
abstract::Ten patients with Stage III-IV ovarian adenocarcinoma were treated with the drug combination etoposide (VP-16) plus cisplatin (DDP). All patients were in relapse following prior vigorous, uninterrupted treatment with three or more lines of chemotherapy that included (1) courses of weekly 1-mg/kg single-agent DDP, (2) ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930320112
更新日期:1986-05-01 00:00:00
abstract:INTRODUCTION:Irreversible electroporation (IRE) has shown promise for ablation of lesions in proximity to vital structures in the preclinical setting. This study aims to evaluate the safety and efficacy of IRE for hepatic tumors in the clinical setting. METHODS:An IRB approved prospective registry of patients undergoi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23280
更新日期:2013-04-01 00:00:00
abstract::Depending on the local extension of primary non-small cell lung cancer (NSCLC) and invaded T4 structure(s), 49 patients underwent complete (CR, n = 14) or palliative (PR, n = 13) resection of exploratory thoracotomy (ET, n = 22) between January 1982 and June 1988. Thoracic radiotherapy (TR) was given to all patients r...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930470402
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:Identification of functional lymphatic vessels and localization of lymphatic vessels are important for lymphaticovenular anastomosis (LVA). Indocyanine green (ICG) lymphography is useful for localization of superficial lymphatic vessels where dermal backflow is not observed, but not for lymphatic vessels in ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24812
更新日期:2018-02-01 00:00:00
abstract::The clinical experience is reviewed in 597 Norwegian testicular cancer patients (age range: 15-45 years) treated from 1979 to 1986. During this period, computer tomography, determination of serum AFP/HCG, and cisplatin-based chemotherapy represented the modern diagnostic and therapeutic modalities. Before orchiectomy ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930390110
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:This study aimed to evaluate treatment outcomes of acral melanoma (AM) based on the excision margin. METHODS:A retrospective cohort study was conducted for patients with primary AM, analyzing recurrence rates, local and in-transit recurrence-free survival (LITRFS), disease-free survival (DFS)...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24442
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:To investigate predictors of occult nipple-areolar complex (NAC) involvement in patients with carcinoma in situ (CIS) and to validate an online probability calculator (CancerMath; www.lifemath.net/cancer/breastcancer/nipplecalc/index.php). METHODS:Mastectomized patients with CIS (n = 104) were retrospective...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24768
更新日期:2017-12-01 00:00:00